Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 20 results.

Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference
Acetylcholinesterase (Ace-2)	Xenobiotic resistance	8 Mutations: Coding, SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	3 References
alcohol dehydrogenase (Adh)	Xenobiotic resistance	10 Mutations:	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Mixed	8 References
Aldehyde dehydrogenase (Aldh)	Xenobiotic resistance	Coding, SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Fry JD; Donlon K; Saweikis M (2008) A worldwide polymorphism in aldehyde dehydrogenase in Drosophila melanogaster: evidence for selectio[...]
CG11699	Xenobiotic resistance	Cis-regulatory, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Association Mapping	Mateo L; Ullastres A; González J (2014) A transposable element insertion confers xenobiotic resistance in Drosophila.
Cyp12d1	Xenobiotic resistance	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Najarro MA; Hackett JL; Smith BR ; et al. (2015) Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in Drosophila.
Cyp28d1	Xenobiotic resistance	2 Mutations: Insertion,	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Mixed	2 References
Cyp28d1-Cyp28d2	Xenobiotic resistance	2 Mutations: Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Mixed	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.
cyp6d2	Xenobiotic resistance	2 Mutations: Coding, SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Mixed	Thomas AM; Hui C; South A ; et al. (2013) Common variants of Drosophila melanogaster Cyp6d2 cause camptothecin sensitivity and synergize with [...]
cyp6g1	Xenobiotic resistance	4 Mutations: Insertion,	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	2 References
glutamate-gated chloride channel (GluCl)	Xenobiotic resistance	Coding, SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Kane NS; Hirschberg B; Qian S ; et al. (2000) Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasit[...]
GSS (glutathione synthetase)	Xenobiotic resistance	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. 1 Additional References Ortiz JG; Opoka R; Kane D (2009) Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for[...]
GSTE1-E10 cluster	Xenobiotic resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Kislukhin G; King EG; Walters KN ; et al. (2013) The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.
kin of irre (kire)	Xenobiotic resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	Montgomery SL; Vorojeikina D; Huang W ; et al. (2014) Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myo[...]
para (kdr)	Xenobiotic resistance	3 Mutations: Coding, SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Pittendrigh B; Reenan R; ffrench-Constant RH ; et al. (1997) Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyr[...] 1 Additional References Dong K; Du Y; Rinkevich F (2014) Molecular biology of insect sodium channels and pyrethroid resistance.
PHGPx	Xenobiotic resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	King EG; Kislukhin G; Walters KN ; et al. (2014) Using Drosophila melanogaster to identify chemotherapy toxicity genes.
resistance to dieldrin	Xenobiotic resistance	3 Mutations:	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	3 References
RnrS	Xenobiotic resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	King EG; Kislukhin G; Walters KN ; et al. (2014) Using Drosophila melanogaster to identify chemotherapy toxicity genes.
SOD1	Xenobiotic resistance	Coding, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Vontas JG; Tsakas SC; Loukas M ; et al. (2001) Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat g[...]
Ugt86Dd	Xenobiotic resistance	Coding, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Association Mapping	Marriage TN; King EG; Long AD ; et al. (2014) Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation inter-cr[...] 1 Additional References Highfill CA; Tran JH; Nguyen SKT (2017) Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanoga[...]
CHKov1	Pathogen resistance Xenobiotic resistance	Coding, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Magwire MM; Bayer F; Webster CL ; et al. (2011) Successive increases in the resistance of Drosophila to viral infection through a transposon inserti[...] 1 Additional References Aminetzach YT; Macpherson JM; Petrov DA (2005) Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila.