Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.
If you use Gephebase for your publication, please cite: Martin, A., & Orgogozo, V. (2013). The loci of repeated evolution: a catalog of genetic hotspots of phenotypic variation. Evolution, 67(5), 1235- 1250.
LAST CURATED PAPERS
; Chase CC
; Olson TA
A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the growth hormone gene.
Rothammer S ; Kunz E ; Seichter D et al. 2017.
Detection of two non-synonymous SNPs in SLC45A2 on BTA20 as candidate causal mutations for oculocutaneous albinism in Braunvieh cattle.
Awasthi Mishra N ; Drögemüller C ; Jagannathan V et al. 2017.
A structural variant in the 5'-flanking region of the TWIST2 gene affects melanocyte development in belted cattle.
WHAT'S NEW ?
Gephebase v.3.0 was launched on January 2019.
The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.