Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.

If you use Gephebase for your publication, please cite: Courtier-Orgogozo, V., Arnoult, L., Prigent, S. R., Wiltgen, S., & Martin, A. (2020). Gephebase, a database of genotype–phenotype relationships for natural and domesticated variation in Eukaryotes. Nucleic acids research, 48(D1), D696-D703.

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Abitbol M ; Bossé P ; Grimard B et al. 2017.
Allelic heterogeneity of albinism in the domestic cat.

Imes DL ; Geary LA ; Grahn RA et al. 2006.
Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation.

Yu Y ; Grahn RA ; Lyons LA 2019.
Mocha tyrosinase variant: a new flavour of cat coat coloration.


Gephebase v.3.0 was launched on January 2019.

The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.