Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.

If you use Gephebase for your publication, please cite: Martin, A., & Orgogozo, V. (2013). The loci of repeated evolution: a catalog of genetic hotspots of phenotypic variation. Evolution, 67(5), 1235- 1250.

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LAST CURATED PAPERS

Palsson A ; Wesolowska N ; Reynisdóttir S et al. 2014.
Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer.

Vontas JG ; Tsakas SC ; Loukas M et al. 2001.
Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat genotoxicity but does not affect near UV radiation damage.

Thomas AM ; Hui C ; South A et al. 2013.
Common variants of Drosophila melanogaster Cyp6d2 cause camptothecin sensitivity and synergize with loss of Brca2.

WHAT'S NEW ?

Gephebase v.3.0 was launched on January 2019.

The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.