Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.

If you use Gephebase for your publication, please cite: Courtier-Orgogozo, V., Arnoult, L., Prigent, S. R., Wiltgen, S., & Martin, A. (2020). Gephebase, a database of genotype–phenotype relationships for natural and domesticated variation in Eukaryotes. Nucleic acids research, 48(D1), D696-D703.

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LAST CURATED PAPERS

Fontaine S ; Caddoux L ; Brazier C et al. 2011.
Uncommon associations in target resistance among French populations of Myzus persicae from oilseed rape crops.

Wu S ; Nomura Y ; Du Y et al. 2017.
Molecular basis of selective resistance of the bumblebee BiNa1 sodium channel to tau-fluvalinate.

Wu Y ; Liu Q ; Qi Y et al. 2021.
Knockdown Resistance (kdr) Mutations I1532T and F1534S Were Identified in Aedes albopictus Field Populations in Zhejiang Province, Central China.

WHAT'S NEW ?

A new review on the genetic loci of pigment pattern evolution in vertebrates, based on Gephebase, is now available in BioRxiv.

The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.