Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.
If you use Gephebase for your publication, please cite: Courtier-Orgogozo, V., Arnoult, L., Prigent, S. R., Wiltgen, S., & Martin, A. (2020). Gephebase, a database of genotype–phenotype relationships for natural and domesticated variation in Eukaryotes. Nucleic acids research, 48(D1), D696-D703.
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LAST CURATED PAPERS
Pischedda A
; Shahandeh MP
; Turner TL
2020.
The Loci of Behavioral Evolution: Evidence That Fas2 and tilB Underlie Differences in Pupation Site Choice Behavior between Drosophila melanogaster and D. simulans.
Mohammadi S
; Yang L
; Harpak A
et al.
2021.
Concerted evolution reveals co-adapted amino acid substitutions in NaK-ATPase of frogs that prey on toxic toads.
Abe G
; Lee SH
; Chang M
et al.
2014.
The origin of the bifurcated axial skeletal system in the twin-tail goldfish.
WHAT'S NEW ?
Gephebase v.3.0 was launched on January 2019.
The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.