Gephebase compiles genotype-phenotype relationships, i.e. associations between a mutation and a phenotypic variation. Gephebase consolidates data from the scientific literature about the genes and the mutations responsible for phenotypic variation in Eukaryotes (mostly animals, yeasts and plants). We plan to include non Eukaryote species in the future. For now, genes responsible for human disease and for aberrant mutant phenotypes in laboratory model organisms are excluded and can be found in other databases (OMIM, OMIA, FlyBase, etc.). QTL mapping studies that did not identify single genes are not included in Gephebase.
If you use Gephebase for your publication, please cite: Martin, A., & Orgogozo, V. (2013). The loci of repeated evolution: a catalog of genetic hotspots of phenotypic variation. Evolution, 67(5), 1235- 1250.
LAST CURATED PAPERS
; VanKuren NW
; Zhao R
Hidden genetic variation shapes the structure of functional elements in Drosophila.
Yokoyama S ; Tada T ; Yamato T 2007 Mar-Apr.
Modulation of the absorption maximum of rhodopsin by amino acids in the C-terminus.
Verhaeghen K ; Van Bortel W ; Trung HD et al. 2010.
Knockdown resistance in Anopheles vagus, An. sinensis, An. paraliae and An. peditaeniatus populations of the Mekong region.
WHAT'S NEW ?
Gephebase v.3.0 was launched on January 2019.
The new fields "Related Genes" and "Related Haplotypes" allow you to browse data related to your phenotype and taxon of interest.
We are looking for volunteers to suggest or curate articles in particular research areas (mouse, xenobiotic resistance, etc.) so please contact us if you are interested!