Gephebase

Summary Table

Your research retrieved 5 results.

Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference
alcohol dehydrogenase (ADH1B)	Xenobiotic resistance	Coding, SNP	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Li H; Mukherjee N; Soundararajan U ; et al. (2007) Geographically separate increases in the frequency of the derived ADH1B47His allele in eastern and [...] 1 Additional References Li H; Mukherjee N; Soundararajan U (2007)* Geographically separate increases in the frequency of the derived ADH1B*47His allele in eastern and [...]
CYP2C9	Xenobiotic resistance	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Association Mapping	Takeuchi F; McGinnis R; Bourgeois S ; et al. (2009) A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinant[...] 1 Additional References Cha PC; Mushiroda T; Takahashi A (2010) Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanes[...]
CYP4F2	Xenobiotic resistance	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Association Mapping	Takeuchi F; McGinnis R; Bourgeois S ; et al. (2009) A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinant[...] 1 Additional References Cha PC; Mushiroda T; Takahashi A (2010) Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanes[...]
MDR1	Xenobiotic resistance	Coding, SNP	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Kimchi-Sarfaty C; Oh JM; Kim IW ; et al. (2007) A "silent" polymorphism in the MDR1 gene changes substrate specificity.
Vkorc1	Xenobiotic resistance	4 Mutations: Coding, SNP	Homo sapiens human - (species) D	Intraspecific	Mixed	Rost S; Fregin A; Ivaskevicius V ; et al. (2004) Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. 2 Additional References Takeuchi F; McGinnis R; Bourgeois S (2009) A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinant[...] Cha PC; Mushiroda T; Takahashi A (2010) Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanes[...]

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