GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001001
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Brassica napus
Trait State in Taxon B
Brassica napus
Ancestral State
Data not curated
Taxonomic Status
Taxon A
Latin Name
Common Name
rape
Synonyms
rape; oilseed rape; rapeseeds; Brassica napus L., 1753
Rank
species
Lineage
Show more ... ina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
rape
Synonyms
rape; oilseed rape; rapeseeds; Brassica napus L., 1753
Rank
species
Lineage
Show more ... ina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
RPM1
Synonyms
DISEASE RESISTANCE PROTEIN RPM1; RESISTANCE TO P. SYRINGAE PV MACULICOLA 1; RESISTANCE TO PSEUDOMONAS SYRINGAE 3; RPS3; At3g07040; F17A9.20
Sequence Similarities
Belongs to the disease resistance NB-LRR family.
UniProtKB
Arabidopsis thaliana
GenebankID or UniProtKB
Presumptive Null
Yes
Molecular Type
Aberration Type
Molecular Details of the Mutation
deletion
Experimental Evidence
Authors
Grant MR; McDowell JM; Sharpe AG; de Torres Zabala M; Lydiate DJ; Dangl JL
Abstract
Plant disease resistance (R) genes confer race-specific resistance to pathogens and are genetically defined on the basis of intra-specific functional polymorphism. Little is known about the evolutionary mechanisms that generate this polymorphism. Most R loci examined to date contain alternate alleles and/or linked homologs even in disease-susceptible plant genotypes. In contrast, the resistance to Pseudomonas syringae pathovar maculicola (RPM1) bacterial resistance gene is completely absent (rpm1-null) in 5/5 Arabidopsis thaliana accessions that lack RPM1 function. The rpm1-null locus contains a 98-bp segment of unknown origin in place of the RPM1 gene. We undertook comparative mapping of RPM1 and flanking genes in Brassica napus to determine the ancestral state of the RPM1 locus. We cloned two B. napus RPM1 homologs encoding hypothetical proteins with approximately 81% amino acid identity to Arabidopsis RPM1. Collinearity of genes flanking RPM1 is conserved between B. napus and Arabidopsis. Surprisingly, we found four additional B. napus loci in which the flanking marker synteny is maintained but RPM1 is absent. These B. napus rpm1-null loci have no detectable nucleotide similarity to the Arabidopsis rpm1-null allele. We conclude that RPM1 evolved before the divergence of the Brassicaceae and has been deleted independently in the Brassica and Arabidopsis lineages. These results suggest that functional polymorphism at R gene loci can arise from gene deletions.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
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