GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001007
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Arabidopsis thaliana- Col0 - resistant
Trait State in Taxon B
Arabidopsis thaliana- Ws0 - sensitive
Ancestral State
Data not curated
Taxonomic Status
Taxon A
Common Name
thale cress
Synonyms
thale cress; mouse-ear cress; thale-cress; Arabidopsis thaliana (L.) Heynh.; Arabidopsis thaliana (thale cress); Arabidopsis_thaliana; Arbisopsis thaliana; thale kress
Rank
species
Lineage
Show more ... ; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Arabidopsis thaliana- Col0 - resistant
Taxon B
Common Name
thale cress
Synonyms
thale cress; mouse-ear cress; thale-cress; Arabidopsis thaliana (L.) Heynh.; Arabidopsis thaliana (thale cress); Arabidopsis_thaliana; Arbisopsis thaliana; thale kress
Rank
species
Lineage
Show more ... ; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Arabidopsis thaliana- Ws0 - sensitive
GENOTYPIC CHANGE
Generic Gene Name
RPP4
Synonyms
DL4460C; FCAALL.47; recognition of peronospora parasitica 4; CHS2; At4g16860; dl4460c
Sequence Similarities
-
GO - Cellular Component
-
UniProtKB
Arabidopsis thaliana
GenebankID or UniProtKB
Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
unknown
Experimental Evidence
Authors
van der Biezen EA; Freddie CT; Kahn K; Parker JE; Jones JD
Abstract
In Arabidopsis, RPP4 confers resistance to Peronospora parasitica (P.p.) races Emoy2 and Emwa1 (downy mildew). We identified RPP4 in Col-0 as a member of the clustered RPP5 multigene family encoding nucleotide-binding leucine-rich repeat proteins with Toll/interleukin-1 receptor domains. RPP4 is the orthologue of RPP5 which, in addition to recognizing P.p. race Noco2, also mediates resistance to Emoy2 and Emwa1. Most differences between RPP4 and RPP5 occur in residues that constitute the TIR domain and in LRR residues that are predicted to confer recognition specificity. RPP4 requires the action of at least 12 defence components, including DTH9, EDS1, PAD4, PAL, PBS2, PBS3, SID1, SID2 and salicylic acid. The ndr1, npr1 and rps5-1 mutations partially compromise RPP4 function in cotyledons but not in true leaves. The identification of RPP4 as a TIR-NB-LRR protein, coupled with its dependence on certain signalling components in true leaves, is consistent with the hypothesis that distinct NB-LRR protein classes differentially signal through EDS1 and NDR1. Our results suggest that RPP4-mediated resistance is developmentally regulated and that in cotyledons there is cross-talk between EDS1 and NDR1 signalling and processes regulating systemic acquired resistance.
Additional References
EXTERNAL LINKS
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