GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001018
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Citrus spp. - blond
Trait State in Taxon B
Citrus sinensis - Sicilian blood oranges
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
-
Synonyms
Citrus L., 1753; Eremocitrus Swingle; Fortunella Swingle; Microcitrus Swingle
Rank
genus
Lineage
Show more ... Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Citrus spp. - blond
Taxon B
Common Name
sweet orange
Synonyms
Citrus x sinensis; sweet orange; Valencia orange; apfelsine; naranja; navel orange; Citrus sinensis (L.) Osbeck; Citrtus sinensis
Rank
species
Lineage
Show more ... phytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Citrus sinensis - Sicilian blood oranges
GENOTYPIC CHANGE
Generic Gene Name
Ruby
Synonyms
-
String
-
Sequence Similarities
-
GO - Biological Process
-
GO - Cellular Component
UniProtKB
Citrus sinensis
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Insertion Size
1-10 kb
Molecular Details of the Mutation
TE (Tcs1) insertion triggering cold-dependent expression
Experimental Evidence
Authors
Butelli E; Licciardello C; Zhang Y; Liu J; Mackay S; Bailey P; Reforgiato-Recupero G; Martin C
Abstract
Traditionally, Sicilian blood oranges (Citrus sinensis) have been associated with cardiovascular health, and consumption has been shown to prevent obesity in mice fed a high-fat diet. Despite increasing consumer interest in these health-promoting attributes, production of blood oranges remains unreliable due largely to a dependency on cold for full color formation. We show that Sicilian blood orange arose by insertion of a Copia-like retrotransposon adjacent to a gene encoding Ruby, a MYB transcriptional activator of anthocyanin production. The retrotransposon controls Ruby expression, and cold dependency reflects the induction of the retroelement by stress. A blood orange of Chinese origin results from an independent insertion of a similar retrotransposon, and color formation in its fruit is also cold dependent. Our results suggest that transposition and recombination of retroelements are likely important sources of variation in Citrus.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
1
COMMENTS
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