GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00001025
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait
Trait State in Taxon A
Drosophila melanogaster
Trait State in Taxon B
Drosophila melanogaster
Ancestral State
Data not curated
Taxonomic Status
Taxon A
Latin Name
Common Name
fruit fly
Synonyms
Sophophora melanogaster; fruit fly; Drosophila melanogaster Meigen, 1830; Sophophora melanogaster (Meigen, 1830); Drosophila melangaster
Rank
species
Lineage
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Brachycera; Muscomorpha; Eremoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
fruit fly
Synonyms
Sophophora melanogaster; fruit fly; Drosophila melanogaster Meigen, 1830; Sophophora melanogaster (Meigen, 1830); Drosophila melangaster
Rank
species
Lineage
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Brachycera; Muscomorpha; Eremoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
sca
Synonyms
AAA28880; AAF58455; anon-EST:Liang-38; CG17579; clone 38; Dmel\CG17579; FBpp0086968; FBpp0086969; mAb sca1; Sca; Sca1b
String
Sequence Similarities
-
GO - Molecular Function
-
GO - Biological Process
GO:0008407 : chaeta morphogenesis
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GO - Cellular Component
GO:0005576 : extracellular region
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Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
unknown; but different sites than for abdomen association
Experimental Evidence
Main Reference
Authors
Lai C; Lyman RF; Long AD; Langley CH; Mackay TF
Abstract
The association between quantitative genetic variation in bristle number and molecular variation at a candidate neurogenic locus, scabrous, was examined in Drosophila melanogaster. Approximately 32 percent of the genetic variation in abdominal bristle number (21 percent for sternopleural bristle number) among 47 second chromosomes from a natural population was correlated with DNA sequence polymorphisms at this locus. Several polymorphic sites associated with large phenotypic effects occurred at intermediate frequency. Quantitative genetic variation in natural populations caused by alleles that have large effects at a few loci and that segregate at intermediate frequencies conflicts with the classical infinitesimal model of the genetic basis of quantitative variation.
Additional References
RELATED GEPHE
Related Genes
Related Haplotypes
EXTERNAL LINKS
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