GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001210
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Heliconius cydno galanthus - "Ac" melanic patch absent = white hourglass pattern present
Trait State in Taxon B
Heliconius pachinus "Ac" melanic patch present = yellow hourglass pattern absent
Ancestral State
Unknown
Taxonomic Status
Taxon A
Common Name
-
Synonyms
Heliconius cydno Doubleday, 1847
Rank
species
Lineage
Show more ... dylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Papilionoidea; Nymphalidae; Heliconiinae; Heliconiini; Heliconius
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Heliconius cydno galanthus - "Ac" melanic patch absent = white hourglass pattern present
Taxon B
Common Name
-
Synonyms
Heliconius cydno pachinus; Heliconius pachinus Salvin, 1871
Rank
species
Lineage
Show more ... dylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Papilionoidea; Nymphalidae; Heliconiinae; Heliconiini; Heliconius
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Heliconius pachinus "Ac" melanic patch present = yellow hourglass pattern absent
GENOTYPIC CHANGE
Generic Gene Name
WntA
Synonyms
-
String
-
Sequence Similarities
Belongs to the Wnt family.
UniProtKB
Vanessa cardui
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Molecular Details of the Mutation
Complex cis-regulatory haplotype : 170 fixed differences were detected among comparisons of allopatric H. c. galanthus and H. pachinus
Experimental Evidence
Authors
Martin A; Papa R; Nadeau NJ; Hill RI; Counterman BA; Halder G; Jiggins CD; Kronforst MR; et al. ... show more
Abstract
Although animals display a rich variety of shapes and patterns, the genetic changes that explain how complex forms arise are still unclear. Here we take advantage of the extensive diversity of Heliconius butterflies to identify a gene that causes adaptive variation of black wing patterns within and between species. Linkage mapping in two species groups, gene-expression analysis in seven species, and pharmacological treatments all indicate that cis-regulatory evolution of the WntA ligand underpins discrete changes in color pattern features across the Heliconius genus. These results illustrate how the direct modulation of morphogen sources can generate a wide array of unique morphologies, thus providing a link between natural genetic variation, pattern formation, and adaptation.
RELATED GEPHE
Related Genes
Related Haplotypes
1
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