GEPHE SUMMARY Print
Gephebase Gene
ABCC2
Entry Status
Published
GepheID
GP00000013
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (insecticide)
Trait State in Taxon A
Plutella xylostella -Bt susceptible
Trait State in Taxon B
Plutella xylostella -Bt resistant
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Plutella xylostella
Common Name
diamondback moth
Synonyms
diamondback moth; cabbage moth; Plutella xylostella (Linnaeus, 1758); Putella xylostella
Rank
species
Lineage
Show more ... a; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Yponomeutoidea; Plutellidae; Plutella
Parent
Plutella () - (Rank: genus)
NCBI Taxonomy ID
51655
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Plutella xylostella
Common Name
diamondback moth
Synonyms
diamondback moth; cabbage moth; Plutella xylostella (Linnaeus, 1758); Putella xylostella
Rank
species
Lineage
Show more ... a; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Yponomeutoidea; Plutellidae; Plutella
Parent
Plutella () - (Rank: genus)
NCBI Taxonomy ID
51655
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
ABCC2
Synonyms
-
String
-
Sequence Similarities
-
GO - Molecular Function
GO:0005524 : ATP binding ... show more
GO - Biological Process
-
GO - Cellular Component
GO:0016021 : integral component of membrane
UniProtKB
Plutella xylostella
A0A0E3ZDK3
GenebankID or UniProtKB
KM245561
Presumptive Null
Yes
Molecular Type
Coding
Aberration Type
Deletion
Deletion Size
10-99 bp
Molecular Details of the Mutation
30bp deletion
Experimental Evidence
Linkage Mapping
Main Reference
Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera. (2011)
Authors
Baxter SW; Badenes-Pérez FR; Morrison A; Vogel H; Crickmore N; Kain W; Wang P; Heckel DG; et al. ... show more
Abstract
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
Additional References
RELATED GEPHE
Related Genes
10 (Acetylcholinesterase (Ace-1), Chitin synthase 1 (CHS1), CYP6BG1, FMO2, glutamate-gated chloride channel (GluCl), MAP4K4, nAChR, para (kdr), resistance to dieldrin, RYR)
Related Haplotypes
No matches found.
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