GEPHE SUMMARY Print
Gephebase Gene
Kit (type III receptor protein-tyrosine kinase)
Entry Status
Published
GepheID
GP00001328
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Morphology
Trait
Coloration (coat)
Trait State in Taxon A
Red fox-standard silver
Trait State in Taxon B
Red fox-Georgian white (GW)
Ancestral State
Taxon A
Taxonomic Status
Domesticated
Taxon A
Latin Name
Vulpes vulpes
Common Name
red fox
Synonyms
Canis vulpes; red fox; silver fox
Rank
species
Lineage
Show more ... ata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Parent
Vulpes () - (Rank: genus)
NCBI Taxonomy ID
9627
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Vulpes vulpes
Common Name
red fox
Synonyms
Canis vulpes; red fox; silver fox
Rank
species
Lineage
Show more ... ata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Parent
Vulpes () - (Rank: genus)
NCBI Taxonomy ID
9627
is Taxon B an Infraspecies?
Yes
Taxon B Description
Red fox-Georgian white (GW)
GENOTYPIC CHANGE
Generic Gene Name
Kit
Synonyms
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; Sl
String
10090.ENSMUSP00000005815
Sequence Similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
GO - Molecular Function
GO:0004888 : transmembrane signaling receptor activity ... show more
GO - Biological Process
GO:0043066 : negative regulation of apoptotic process ... show more
GO - Cellular Component
GO:0005886 : plasma membrane ... show more
UniProtKB
Mus musculus
P05532
GenebankID or UniProtKB
Presumptive Null
Unknown
Molecular Type
Unknown
Aberration Type
Unknown
Molecular Details of the Mutation
unknown
Experimental Evidence
Association Mapping
Main Reference
Georgian white coat color of red fox (Vulpes vulpes) maps to fox chromosome 2 in the region containing KIT gene. (2016)
Authors
Kukekova AV; Johnson JL; Kharlamova AV; Vladimirova AV; Shepeleva DV; Gulevich RG; Trut LN
Abstract
-
Additional References
RELATED GEPHE
Related Genes
2 (Agouti, MC1R)
Related Haplotypes
1
EXTERNAL LINKS
COMMENTS
GW homozygous die as embryos if not they are almost completely white and die at 1-2 months of age
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