GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001352
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Domestic duck ; Wild type non-extended black-(Jingjiang and Shanna and Shaoxing and Youxian and Jinyun and Mallard)
Trait State in Taxon B
Domestic duck-extended black-(Black Putian and Black Jingwu)
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
mallard
Synonyms
Anas boschas; Anas domesticus; Anas platyrhynchos f. domestica; mallard; duck; mallard duck; mallard ducks; Anas platyrhynchos Linnaeus 1758; Anas platyrhynchus
Rank
species
Lineage
Show more ... podomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Anas
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Domestic duck ; Wild type non-extended black-(Jingjiang and Shanna and Shaoxing and Youxian and Jinyun and Mallard)
Taxon B
Common Name
mallard
Synonyms
Anas boschas; Anas domesticus; Anas platyrhynchos f. domestica; mallard; duck; mallard duck; mallard ducks; Anas platyrhynchos Linnaeus 1758; Anas platyrhynchus
Rank
species
Lineage
Show more ... podomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Anas
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Domestic duck-extended black-(Black Putian and Black Jingwu)
GENOTYPIC CHANGE
Presumptive Null
No
Molecular Type
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
c.52G>A p.Glu18Lys
Experimental Evidence
Taxon A Taxon B Position
Codon - - -
Amino-acid - - -
Authors
Yu W; Wang C; Xin Q; Li S; Feng Y; Peng X; Gong Y
Abstract
In this study, we performed a sequence characterization of the duck melanocortin 1 receptor (alpha-melanocyte stimulating hormone receptor) (MC1R) gene to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extended black (E) and non-extended black (e(+) ) allele hypothesis of the duck MC1R gene. Both c.52G>A and c.376G>A substitutions are highly associated with the duck extended black variant (P < 0.01), but the novel c.52G>A substitution is more of a fit for the allele hypothesis of the duck MC1R gene.

© 2012 The Authors, Animal Genetics © 2012 Stichting International Foundation for Animal Genetics.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
the p.Glu18Lys is assumed to have created a hyperactive MC1R protein - it is also mostly associated to c.376G>A
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