GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001408
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
early flowering Domesticated sorghum line TX623
Trait State in Taxon B
Late flowering wild sorghum & Domesticated sorghum from Ethiopia Yemen Germany & China
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
sorghum
Synonyms
Andropogon sorghum; Sorghum bicolor subsp. bicolor; Sorghum nervosum; Sorghum saccharatum; Sorghum vulgare; sorghum; broomcorn; milo; Andropogon sorghum (L.) Brot.; Sorghum bicolor (L.) Moench; Sorghum nervosum Besser ex Schult.; Sorghum saccharatum (L.) Moench; Sorghum vulgare Pers.; Sorghum bicolor milo; Sorghum_bicolor
Rank
species
Lineage
Show more ... yta; Euphyllophyta; Spermatophyta; Magnoliopsida; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
early flowering Domesticated sorghum line TX623
Taxon B
Common Name
-
Synonyms
Sorghum bicolor var. virgatum; Sorghum bicolor var. virgatum (Hack.) de Wet & Huckabay, nom. inval.; Sorghum virgatum (Hack.) Stapf
Rank
species
Lineage
Show more ... yta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Late flowering wild sorghum & Domesticated sorghum from Ethiopia Yemen Germany & China
GENOTYPIC CHANGE
UniProtKB
Arabidopsis thaliana
GenebankID or UniProtKB
Presumptive Null
Yes
Molecular Type
Aberration Type
Deletion Size
1-9 bp
Molecular Details of the Mutation
5bp deletion in the coding sequence leading to gene frameshift
Experimental Evidence
Authors
Liu H; Liu H; Zhou L; Zhang Z; Zhang X; Wang M; Li H; Lin Z
Abstract
Flowering time is one of the key determinants of crop adaptation to local environments during domestication. However, the genetic basis underlying flowering time is yet to be elucidated in most cereals. Although staple cereals, such as rice, maize, wheat, barley, and sorghum, have spread and adapted to a wide range of ecological environments during domestication, it is yet to be determined whether they have a common genetic basis for flowering time. In this study, we show, through map-based cloning, that flowering time in sorghum is controlled by a major quantitative trait locus (QTL) Heading Date 1 (HD1), located on chromosome 10. The causal gene encodes the CONSTANS gene family which contains a CCT domain. A 5-bp deletion of a minor allele present in the coding sequence leads to a gene frameshift that delays flowering in sorghum. In contrast, in foxtail millet, association mapping of HD1 showed a common causal site with a splicing variant from "GT" to "AT" that was highly correlated with flowering time. In addition, the rice HD1 gene is known to harbor several causal variants controlling flowering time. These data indicate that the major flowering time QTL HD1 was under parallel domestication in sorghum, foxtail millet, and rice. The pattern of common mixed minor, or even rare, causal alleles in HD1 across different species may be representative of the genetic basis of the domestication syndrome. Furthermore, large DNA sequence analysis of HD1 revealed multiple origins for domesticated sorghum and a single origin for domesticated foxtail millet.

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Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
it is unclear in which allele is the mutation and paper is confusing wether wild type is early or late flowering
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