GEPHE SUMMARY Print
Thalarctos maritimus; polar bear; white bear
Show more ... rata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
NCBI Taxonomy ID
is Taxon A an Infraspecies?
giant panda; Ailuropoda melanoleuca (David, 1869); Ailuropoda melanoleura
Show more ... Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Generic Gene Name
TR1; T1r1; Gpr70; Tr1
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
GO - Molecular Function
GO:0004930 : G protein-coupled receptor activity ... show more
GO - Biological Process
GO - Cellular Component
Molecular Details of the Mutation
pseudogene due to three indel mutations in the third and sixth exons. The giant panda has one 2-bp insertion on the third exon and two deletions (6-bp and 4-bp) on the sixth exon,
Li R; Fan W; Tian G; Zhu H; He L; Cai J; Huang Q; Cai Q; et al. ... show more
Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% of the whole genome, and the remaining gaps (0.05 Gb) seem to contain carnivore-specific repeats and tandem repeats. Comparisons with the dog and human showed that the panda genome has a lower divergence rate. The assessment of panda genes potentially underlying some of its unique traits indicated that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition. We also identified more than 2.7 million heterozygous single nucleotide polymorphisms in the diploid genome. Our data and analyses provide a foundation for promoting mammalian genetic research, and demonstrate the feasibility for using next-generation sequencing technologies for accurate, cost-effective and rapid de novo assembly of large eukaryotic genomes.
Note that the derived phenotype may have appeared during evolution due to another mutation; and that the mutation described here might have occurred subsequently; as a neutral mutation.
YOUR FEEDBACK is welcome!