GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001544
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
D. m. malerkotliana with darker male abdominal pigmentation
Trait State in Taxon B
D. m. pallens with light colored male abdominal pigmentation
Ancestral State
Unknown
Taxonomic Status
Taxon A
Common Name
-
Synonyms
-
Rank
species
Lineage
Show more ... remoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; bipectinata species complex
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
D. m. malerkotliana with darker male abdominal pigmentation
Taxon B
Common Name
-
Synonyms
-
Rank
species
Lineage
Show more ... remoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; bipectinata species complex
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
D. m. pallens with light colored male abdominal pigmentation
GENOTYPIC CHANGE
Presumptive Null
No
Molecular Type
Aberration Type
SNP
Molecular Details of the Mutation
5 changes including 4 SNP and 1bp indel in the first intron
Experimental Evidence
Authors
Signor SA; Liu Y; Rebeiz M; Kopp A
Abstract
Convergent evolution provides a type of natural replication that can be exploited to understand the roles of contingency and constraint in the evolution of phenotypes and the gene networks that control their development. For sex-specific traits, convergence offers the additional opportunity for testing whether the same gene networks follow different evolutionary trends in males versus females. Here, we use an unbiased, systematic mapping approach to compare the genetic basis of evolutionary changes in male-limited pigmentation in several pairs of Drosophila species that represent independent evolutionary transitions. We find strong evidence for repeated recruitment of the same genes to specify similar pigmentation in different species. At one of these genes, ebony, we observe convergent evolution of sexually dimorphic and monomorphic expression through cis-regulatory changes. However, this functional convergence has a different molecular basis in different species, reflecting both parallel fixation of ancestral alleles and independent origin of distinct mutations with similar functional consequences. Our results show that a strong evolutionary constraint at the gene level is compatible with a dominant role of chance at the molecular level.

Copyright © 2016 Elsevier Ltd. All rights reserved.
Additional References
RELATED GEPHE
Related Genes
Related Haplotypes
No matches found.
COMMENTS
@ILS or @Introgression - @SexualTrait - A large QTL on 3R (3R1) including ebony; ebony is not expressed in segments that are completely black in darker species while it is expressed in a wider pattern in light colored taxa. Involvement of ebony demonstrated by RNAi experiments and evidence of cis-regulatory differences by sequencing of transcript in F1 hybrid. The causative variants in ebony may be due either to parallel fixation of ancestral alleles or to interspecific introgression (with the couple D. bipectinata-D. parabipectinata). For the light forms (D. bipectinata & D. m. pallens) phylogenetic analysis supports a sorting of ancestral polymorphisms.
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