GEPHE SUMMARY
Entry Status
Published
GepheID
GP00001563
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Chinese Spring (CS) wheat susceptible
Trait State in Taxon B
Chinese wheat cultivar Sumai3 resistant
Ancestral State
Unknown
Taxonomic Status
Taxon A
Common Name
bread wheat
Synonyms
Triticum aestivum subsp. aestivum; Triticum vulgare; bread wheat; Canadian hard winter wheat; common wheat; wheat; Triticum aestivum L.; Triticum vulgare L.; Triticum vulgare Vill., nom. illeg.; Tricum aestivum; Triticum aestivam; Triticum aestivum8
Rank
species
Lineage
Show more ... a; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Chinese Spring (CS) wheat susceptible
Taxon B
Common Name
bread wheat
Synonyms
Triticum aestivum subsp. aestivum; Triticum vulgare; bread wheat; Canadian hard winter wheat; common wheat; wheat; Triticum aestivum L.; Triticum vulgare L.; Triticum vulgare Vill., nom. illeg.; Tricum aestivum; Triticum aestivam; Triticum aestivum8
Rank
species
Lineage
Show more ... a; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Chinese wheat cultivar Sumai3 resistant
GENOTYPIC CHANGE
Generic Gene Name
-
Synonyms
-
String
-
Sequence Similarities
-
GO - Molecular Function
-
UniProtKB
Triticum aestivum
GenebankID or UniProtKB
Presumptive Null
Yes
Molecular Type
Aberration Type
Indel Size
10-100 kb
Molecular Details of the Mutation
PFT gene is present and constitutively expressed in resistant line and absent in susceptible line
Experimental Evidence
Authors
Rawat N; Pumphrey MO; Liu S; Zhang X; Tiwari VK; Ando K; Trick HN; Bockus WW; et al. ... show more
Abstract
Fusarium head blight (FHB), caused by Fusarium graminearum, is a devastating disease of wheat and barley that leads to reduced yield and mycotoxin contamination of grain, making it unfit for human consumption. FHB is a global problem, with outbreaks in the United States, Canada, Europe, Asia and South America. In the United States alone, total direct and secondary economic losses from 1993 to 2001 owing to FHB were estimated at $7.67 billion. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding. Here we report the map-based cloning of Fhb1 from a Chinese wheat cultivar Sumai 3. By mutation analysis, gene silencing and transgenic overexpression, we show that a pore-forming toxin-like (PFT) gene at Fhb1 confers FHB resistance. PFT is predicted to encode a chimeric lectin with two agglutinin domains and an ETX/MTX2 toxin domain. Our discovery identifies a new type of durable plant resistance gene conferring quantitative disease resistance to plants against Fusarium species.
Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
COMMENTS
Considered null mutation when absent. PFT is predicted to encode a chimeric lectin with two agglutinin domains and an ETX/MTX2 toxin domain. Demonstrated by mutation analysis; gene silencing and transgenic overexpression
YOUR FEEDBACK is welcome!