GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001567
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Drought-sensitive maize
Trait State in Taxon B
Drought-tolerant maize
Ancestral State
Unknown
Taxonomic Status
Taxon A
Latin Name
Common Name
-
Synonyms
Zea mays var. japonica; maize; Zea mays L.; Zea mays mays
Rank
species
Lineage
Show more ... phyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
B73 (genome) line and other drought-sensitive maize cultivars (GWAS)
Taxon B
Latin Name
Common Name
-
Synonyms
Zea mays var. japonica; maize; Zea mays L.; Zea mays mays
Rank
species
Lineage
Show more ... phyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
CIMBL55 line and other drought-tolerant maize cultivars (GWAS)
GENOTYPIC CHANGE
UniProtKB
Zea mays subsp. mays
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Insertion Size
100-999 bp
Molecular Details of the Mutation
A 366-bp insertion in the promoter containing 3 MYB cis elements confers drought-inducible expression of ZmVPP1 in drought-tolerant genotypes
Experimental Evidence
Authors
Wang X; Wang H; Liu S; Ferjani A; Li J; Yan J; Yang X; Qin F
Abstract
Maize production is threatened by drought stress worldwide. Identification of the genetic components underlying drought tolerance in maize is of great importance. Here we report a genome-wide association study (GWAS) of maize drought tolerance at the seedling stage that identified 83 genetic variants, which were resolved to 42 candidate genes. The peak GWAS signal showed that the natural variation in ZmVPP1, encoding a vacuolar-type H(+) pyrophosphatase, contributes most significantly to the trait. Further analysis showed that a 366-bp insertion in the promoter, containing three MYB cis elements, confers drought-inducible expression of ZmVPP1 in drought-tolerant genotypes. Transgenic maize with enhanced ZmVPP1 expression exhibits improved drought tolerance that is most likely due to enhanced photosynthetic efficiency and root development. Taken together, this information provides important genetic insights into the natural variation of maize drought tolerance. The identified loci or genes can serve as direct targets for both genetic engineering and selection for maize trait improvement.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
COMMENTS
Non-null mutation. The associated SNP contributes to 10% (the most significant) of the phenotypic variance
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