GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00001592
Main curator
Prigent
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
nipponbare japonica (NIPB) cultivar without this resistance
Trait State in Taxon B
Chinese rice variety Gumei 4 resistant
Ancestral State
Unknown
Taxonomic Status
Taxon A
Latin Name
Common Name
rice
Synonyms
rice; red rice; Oryza sativa L.
Rank
species
Lineage
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ytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Parent
NCBI Taxonomy ID
is Taxon A an Infraspecies?
Yes
Taxon A Description
Nipponbare japonica (NIPB) cultivar without this resistance
Taxon B
Latin Name
Common Name
rice
Synonyms
rice; red rice; Oryza sativa L.
Rank
species
Lineage
Show more ...
ytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Parent
NCBI Taxonomy ID
is Taxon B an Infraspecies?
Yes
Taxon B Description
Chinese rice variety Gumei 4 resistant
GENOTYPIC CHANGE
Generic Gene Name
Pigm_GM4.7
Synonyms
-
String
-
Sequence Similarities
Belongs to the disease resistance NB-LRR family.
GO - Molecular Function
GO - Biological Process
-
GO - Cellular Component
-
UniProtKB
Oryza sativa subsp. indica
Oryza sativa subsp. indica
Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
unknown
Experimental Evidence
Main Reference
Authors
Deng Y; Zhai K; Xie Z; Yang D; Zhu X; Liu J; Wang X; Qin P; et al.
... show more
Abstract
Crop breeding aims to balance disease resistance with yield; however, single resistance (R) genes can lead to resistance breakdown, and R gene pyramiding may affect growth fitness. Here we report that the rice Pigm locus contains a cluster of genes encoding nucleotide-binding leucine-rich repeat (NLR) receptors that confer durable resistance to the fungus Magnaporthe oryzae without yield penalty. Among these NLR receptors, PigmR confers broad-spectrum resistance, whereas PigmS competitively attenuates PigmR homodimerization to suppress resistance. PigmS expression, and thus PigmR-mediated resistance, are subjected to tight epigenetic regulation. PigmS increases seed production to counteract the yield cost induced by PigmR Therefore, our study reveals a mechanism balancing high disease resistance and yield through epigenetic regulation of paired antagonistic NLR receptors, providing a tool to develop elite crop varieties.
Copyright © 2017, American Association for the Advancement of Science.
Copyright © 2017, American Association for the Advancement of Science.
Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
PigmR displayed constitutive low-level expression in all tissues and is repressed by PigmS in pollen and panicles. Susceptible varieties may not have this gene?
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