GEPHE SUMMARY Print
Entry Status
Published
GepheID
GP00000161
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Heliothis virescens - Bt susceptible
Trait State in Taxon B
Heliothis virescens - Bt resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
tobacco budworm
Synonyms
tobacco budworm; Chloridea virescens; Helicoverpa virescens; Heliothis virescens (Fabricius, 1777)
Rank
species
Lineage
Show more ... poda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Noctuoidea; Noctuidae; Heliothinae; Heliothis
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
tobacco budworm
Synonyms
tobacco budworm; Chloridea virescens; Helicoverpa virescens; Heliothis virescens (Fabricius, 1777)
Rank
species
Lineage
Show more ... poda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Noctuoidea; Noctuidae; Heliothinae; Heliothis
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Presumptive Null
Yes
Molecular Type
Aberration Type
Insertion Size
1-10 kb
Molecular Details of the Mutation
Insertion of retrotransposon
Experimental Evidence
Authors
Gahan LJ; Gould F; Heckel DG
Abstract
Transgenic crops producing insecticidal toxins from Bacillus thuringiensis (Bt) are widely used for pest control. Bt-resistant insect strains have been studied, but the molecular basis of resistance has remained elusive. Here, we show that disruption of a cadherin-superfamily gene by retrotransposon-mediated insertion was linked to high levels of resistance to the Bt toxin Cry1Ac in the cotton pest Heliothis virescens. Monitoring the early phases of Bt resistance evolution in the field has been viewed as crucial but extremely difficult, especially when resistance is recessive. Our findings enable efficient DNA-based screening for resistant heterozygotes by directly detecting the recessive allele.
Additional References
RELATED GEPHE
Related Genes
Related Haplotypes
No matches found.
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