GEPHE SUMMARY Print
Gephebase Gene
beta-tubulin
Entry Status
Published
GepheID
GP00001801
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (benomyl)
Trait State in Taxon A
sensitive
Trait State in Taxon B
resistant
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Penicillium digitatum
Common Name
-
Synonyms
Penicillum digitatum
Rank
species
Lineage
cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium
Parent
Penicillium () - (Rank: genus)
NCBI Taxonomy ID
36651
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Penicillium digitatum
Common Name
-
Synonyms
Penicillum digitatum
Rank
species
Lineage
cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium
Parent
Penicillium () - (Rank: genus)
NCBI Taxonomy ID
36651
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
TUB2
Synonyms
ARM10; SHE8; YFL037W
String
4932.YFL037W
Sequence Similarities
Belongs to the tubulin family.
GO - Molecular Function
GO:0005525 : GTP binding ... show more
GO - Biological Process
GO:0007010 : cytoskeleton organization ... show more
GO - Cellular Component
GO:0005737 : cytoplasm ... show more
UniProtKB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P02557
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Coding
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
Glu1198Lys
Experimental Evidence
Candidate Gene
Taxon A Taxon B Position
Codon GAG AAG -
Amino-acid Glu Lys 198
Main Reference
Characterization of mutations in the beta-tubulin gene of benomyl-resistant field strains of Venturia inaequalis and other plant pathogenic fungi. .
Authors
Koenraadt Harrie; Somerville Shauna C; Jones AL
Abstract
-
Additional References
Mechanism of action of N-phenylcarbamates in benzimidazole-resistant Neurospora strains . (1990 )
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
The amino acid change Glu198Gly was shown to confer resistance in Neurospora crassa
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