GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00001819
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
sensitive
Trait State in Taxon B
resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
-
Synonyms
Ostertagia circumcincta; Teladoragia circumcincta
Rank
species
Lineage
cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Strongylida; Trichostrongyloidea; Haemonchidae; Teladorsagia
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
-
Synonyms
Ostertagia circumcincta; Teladoragia circumcincta
Rank
species
Lineage
cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Strongylida; Trichostrongyloidea; Haemonchidae; Teladorsagia
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
TUB2
Synonyms
ARM10; SHE8; YFL037W
String
Sequence Similarities
Belongs to the tubulin family.
GO - Molecular Function
GO:0005525 : GTP binding
... show more
GO - Biological Process
GO:0007010 : cytoskeleton organization
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GO - Cellular Component
GO:0005737 : cytoplasm
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UniProtKB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Presumptive Null
Molecular Type
Aberration Type
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
Phe167Tyr
Experimental Evidence
| Taxon A | Taxon B | Position | |
|---|---|---|---|
| Codon | - | - | - |
| Amino-acid | Phe | Tyr | 167 |
Main Reference
Authors
Silvestre A; Cabaret J
Abstract
-
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
EXTERNAL LINKS
COMMENTS
In vitro assays have demonstrated that Phe167Tyr in b-tubulin impeded BZ binding in S. cerevisiae
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