GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00001886
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Kochia scoparia - sensitive
Trait State in Taxon B
Kochia scoparia - resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
-
Synonyms
Kochia densiflora; Kochia scoparia; burning bush; summer cypress; Bassia scoparia (L.) A.J.Scott, 1978; Kochia densiflora Turcz. ex Aellen, 1954; Kochia scoparia (L.) Schrad., 1809; Bassia scorpia
Rank
species
Lineage
Show more ... bryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliopsida; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Camphorosmoideae; Camphorosmeae; Bassia
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
-
Synonyms
Kochia densiflora; Kochia scoparia; burning bush; summer cypress; Bassia scoparia (L.) A.J.Scott, 1978; Kochia densiflora Turcz. ex Aellen, 1954; Kochia scoparia (L.) Schrad., 1809; Bassia scorpia
Rank
species
Lineage
Show more ... bryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliopsida; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Camphorosmoideae; Camphorosmeae; Bassia
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
UniProtKB
Arabidopsis thaliana
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Insertion Size
10-100 kb
Molecular Details of the Mutation
15-25 copies of the EPSPS gene
Experimental Evidence
Authors
Sammons RD; Gaines TA
Abstract
Studies of mechanisms of resistance to glyphosate have increased current understanding of herbicide resistance mechanisms. Thus far, single-codon non-synonymous mutations of EPSPS (5-enolypyruvylshikimate-3-phosphate synthase) have been rare and, relative to other herbicide mode of action target-site mutations, unconventionally weak in magnitude for resistance to glyphosate. However, it is possible that weeds will emerge with non-synonymous mutations of two codons of EPSPS to produce an enzyme endowing greater resistance to glyphosate. Today, target-gene duplication is a common glyphosate resistance mechanism and could become a fundamental process for developing any resistance trait. Based on competition and substrate selectivity studies in several species, rapid vacuole sequestration of glyphosate occurs via a transporter mechanism. Conversely, as the chloroplast requires transporters for uptake of important metabolites, transporters associated with the two plastid membranes may separately, or together, successfully block glyphosate delivery. A model based on finite glyphosate dose and limiting time required for chloroplast loading sets the stage for understanding how uniquely different mechanisms can contribute to overall glyphosate resistance.

© 2014 The Authors. Pest Management Science published by JohnWiley & Sons Ltd on behalf of Society of Chemical Industry.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
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