GEPHE SUMMARY Print
Entry Status
Published
GepheID
GP00002013
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Tetranychus urticae - sensitive
Trait State in Taxon B
Tetranychus urticae - resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
two-spotted spider mite
Synonyms
two-spotted spider mite; red spider mite; twospotted mite; Tetranychus urticae Koch, 1836
Rank
species
Lineage
Show more ... ia; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Chelicerata; Arachnida; Acari; Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae; Tetranychoidea; Tetranychidae; Tetranychus
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
two-spotted spider mite
Synonyms
two-spotted spider mite; red spider mite; twospotted mite; Tetranychus urticae Koch, 1836
Rank
species
Lineage
Show more ... ia; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Chelicerata; Arachnida; Acari; Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae; Tetranychoidea; Tetranychidae; Tetranychus
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
UniProtKB
Drosophila melanogaster
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
several non-synonymous SNP - exact causing amino acid change(s) unknown
Experimental Evidence
Taxon A Taxon B Position
Codon - - -
Amino-acid - - -
Authors
Anazawa Y; Tomita T; Aiki Y; Kozaki T; Kono Y
Abstract
Acetylcholinesterase (AChE) from two-spotted spider mites, Tetranychus urticae was compared between an organophosphate susceptible (TKD) and a resistant (NCN) strain. The AChE of TKD had lower affinity to acetylthiocholine and propionylthiocholine than that of NCN, and the inhibition of AChE by DDVP, ambenonium, eserine and n-methyl-eserine showed that NCN was more insensitive than TKD. AChE cDNA sequence was determined, and the 687 amino acids of primary structure were deduced. There were six replacements of amino acid residues in TKD and two in NCN. #F331(439)C was the only substitution unique to NCN, however, this mutation existed homozygously in only two out of nine mites. This residue is one of the gorge lining components, and #F331(439)C might act an important role in the sensitivity of AChE to the inhibitors.
Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
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