GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00002015
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Myzus persicae - sensitive
Trait State in Taxon B
Myzus persicae- resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
green peach aphid
Synonyms
Myzus (Nectarosiphon) persicae; green peach aphid; peach-potato aphid; Myzus persicae (Sulzer, 1776); Myzus persiceae
Rank
species
Lineage
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Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha; Aphidoidea; Aphididae; Aphidinae; Macrosiphini; Myzus
Parent
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
green peach aphid
Synonyms
Myzus (Nectarosiphon) persicae; green peach aphid; peach-potato aphid; Myzus persicae (Sulzer, 1776); Myzus persiceae
Rank
species
Lineage
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Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha; Aphidoidea; Aphididae; Aphidinae; Macrosiphini; Myzus
Parent
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
Ace
Synonyms
AcChE; ace; ACE; ace-2; ache; AchE; AChE; CG17907; CHE; dAChE; dmAChE; DmAChE; Dmel\CG17907; Dm_ace; FBgn0000024; l(3)26; l(3)87Ed
String
Sequence Similarities
Belongs to the type-B carboxylesterase/lipase family.
GO - Molecular Function
GO:0042803 : protein homodimerization activity
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GO - Biological Process
GO:0006581 : acetylcholine catabolic process
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GO - Cellular Component
GO:0005886 : plasma membrane
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UniProtKB
Drosophila melanogaster
Drosophila melanogaster
Presumptive Null
Molecular Type
Aberration Type
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
Ser431Phe (position 331 in mature Torpedo protein)
Experimental Evidence
| Taxon A | Taxon B | Position | |
|---|---|---|---|
| Codon | - | - | - |
| Amino-acid | - | - | - |
Authors
Nabeshima T; Kozaki T; Tomita T; Kono Y
Abstract
cDNAs encoding two acetylcholinesterases (AChEs) were isolated from the peach potato aphid, Myzus persicae. MpAChE1 was orthologous and MpAChE2 was paralogous with the ace of Drosophila melanogaster. The deduced amino acid sequence of MpAChE1 cDNA was identical between the pirimicarb susceptible and resistant strains. However, a single amino acid substitution of Ser431Phe on MpAchE2 was found in the pirimicarb resistant strains. This substitution was located in the acyl pocket of the enzyme and was thought to alter the ligand specificity.
Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
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