GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00002148
Main curator
Santos
PHENOTYPIC CHANGE
Trait Category
Trait
Trait State in Taxon A
All-black carrion crows
Trait State in Taxon B
Grey-coated hooded crows
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
-
Synonyms
Corvus corone corone Linnaeus, 1758
Rank
subspecies
Lineage
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orpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae; Corvus; Corvus corone
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
hooded crow
Synonyms
Corvus corone cornix; hooded crow; Nebelkraehe; hoodiecrow; Corvus cornix Linnaeus, 1758
Rank
species
Lineage
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Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae; Corvus
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
Ndp
Synonyms
ND; Ndph
String
Sequence Similarities
-
GO - Molecular Function
GO:0042803 : protein homodimerization activity
... show more
GO - Biological Process
GO - Cellular Component
GO:0062023 : collagen-containing extracellular matrix
... show more
UniProtKB
Mus musculus
Mus musculus
Presumptive Null
Molecular Type
Aberration Type
Insertion Size
1-10 kb
Molecular Details of the Mutation
2.25-kb LTR retrotransposon insertion reducing expression of the NDP gene and candidate gene LRP6 and a large LD haplotype in chr.18 also show a signal
Experimental Evidence
Main Reference
Authors
Knief U; Bossu CM; Saino N; Hansson B; Poelstra J; Vijay N; Weissensteiner M; Wolf JBW
Abstract
The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene flow.
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
@TE ; genotypes described in "Discovery and population genomics of structural variation in a songbird genus"
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