GEPHE SUMMARY Print
Entry Status
Published
GepheID
GP00000236
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Nasonia vitripennis
Trait State in Taxon B
Nasonia giraulti
Ancestral State
Data not curated
Taxonomic Status
Taxon A
Common Name
jewel wasp
Synonyms
jewel wasp; Nasonia vitripennis (Walker, 1836)
Rank
species
Lineage
Show more ... thropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Parasitoida; Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
-
Synonyms
Nasonia giraulti Darling, 1990
Rank
species
Lineage
Show more ... thropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Parasitoida; Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
dsx
Synonyms
CG11094; Dmdsx; Dmel\CG11094; Dsx; DSX; dsxF; dsxM; Hr; ix-62c
Sequence Similarities
-
GO - Cellular Component
UniProtKB
Drosophila melanogaster
GenebankID or UniProtKB
Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
various
Experimental Evidence
Authors
Loehlin DW; Oliveira DC; Edwards R; Giebel JD; Clark ME; Cattani MV; van de Zande L; Verhulst EC; et al. ... show more
Abstract
The genetic basis of morphological differences among species is still poorly understood. We investigated the genetic basis of sex-specific differences in wing size between two closely related species of Nasonia by positional cloning a major male-specific locus, wing-size1 (ws1). Male wing size increases by 45% through cell size and cell number changes when the ws1 allele from N. giraulti is backcrossed into a N. vitripennis genetic background. A positional cloning approach was used to fine-scale map the ws1 locus to a 13.5 kilobase region. This region falls between prospero (a transcription factor involved in neurogenesis) and the master sex-determining gene doublesex. It contains the 5'-UTR and cis-regulatory domain of doublesex, and no coding sequence. Wing size reduction correlates with an increase in doublesex expression level that is specific to developing male wings. Our results indicate that non-coding changes are responsible for recent divergence in sex-specific morphology between two closely related species. We have not yet resolved whether wing size evolution at the ws1 locus is caused by regulatory alterations of dsx or prospero, or by another mechanism. This study demonstrates the feasibility of efficient positional cloning of quantitative trait loci (QTL) involved in a broad array of phenotypic differences among Nasonia species.
Additional References
RELATED GEPHE
Related Genes
Related Haplotypes
No matches found.
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