GEPHE SUMMARY Print
Entry Status
Published
GepheID
GP00000024
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Pan troglodytes - blood group A
Trait State in Taxon B
Pan troglodytes - allele Odel
Ancestral State
Data not curated
Taxonomic Status
Taxon A
Common Name
chimpanzee
Synonyms
chimpanzee; Chimpansee troglodytes
Rank
species
Lineage
Show more ... copterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
chimpanzee
Synonyms
chimpanzee; Chimpansee troglodytes
Rank
species
Lineage
Show more ... copterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
unknown
Experimental Evidence
Authors
Kermarrec N; Roubinet F; Apoil PA; Blancher A
Abstract
Like humans, non-human primates express the antigens A and B of the ABO histoblood group system. In chimpanzees, only A and O types are found, while the types A, B, AB, and O are found in macaques. The sequences of exons 6 and 7 of two chimpanzee O alleles (Odel and O(x), two macaque species O alleles (rhesus monkey and crab-eating macaque), and sequences of exon 7 of two major chimpanzee A alleles (A1ch and A2ch) were established. The sequences of cDNAs corresponding to the chimpanzee and rhesus monkey O alleles were characterized from exon 1 to 7 and from exon 4 to 7, respectively. A comparison of our results with ABO gene sequences already published by others demonstrates that human and non-human primate O alleles are species-specific and result from independent silencing mutations. These observations reinforce the hypothesis that the maintenance of the ABO gene polymorphism in primates reflects convergent evolution more than transpecies inheritance of ancestor alleles.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
1
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