GEPHE SUMMARY
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Gephebase Gene
Entry Status
Published
GepheID
GP00002387
Main curator
Santos
PHENOTYPIC CHANGE
Trait Category
Trait
Trait State in Taxon A
less extensive carotenoid pigmentation
Trait State in Taxon B
more extensive carotenoid pigmentation
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
Chestnut-sided warbler
Synonyms
Dendroica pensylvanica; Chestnut-sided warbler; Setophaga pensylvanica (Linnaeus, 1766)
Rank
species
Lineage
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etrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Parulidae; Setophaga
Parent
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
yellow warbler
Synonyms
Dendroica petechia; yellow warbler; Setophaga petechia (Linnaeus, 1766)
Rank
species
Lineage
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etrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Parulidae; Setophaga
Parent
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
BCO2
Synonyms
BCDO2; B-DIOX-II
String
Sequence Similarities
Belongs to the carotenoid oxygenase family.
GO - Molecular Function
GO:0046872 : metal ion binding
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GO - Biological Process
GO:0055114 : oxidation-reduction process
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GO - Cellular Component
GO:0005739 : mitochondrion
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UniProtKB
Homo sapiens
Homo sapiens
Presumptive Null
Molecular Type
Aberration Type
Molecular Details of the Mutation
-
Experimental Evidence
Main Reference
Authors
Baiz MD; Wood AW; Brelsford A; Lovette IJ; Toews DPL
Abstract
Species radiations have long served as model systems in evolutionary biology. However, it has only recently become possible to study the genetic bases of the traits responsible for diversification and only in a small number of model systems. Here, we use genomes of 36 species of North, Central, and South American warblers to highlight the role of pigmentation genes-involved in melanin and carotenoid processing-in the diversification of this group. We show that agouti signaling protein (ASIP) and beta-carotene oxygenase 2 (BCO2) are predictably divergent between species that differ in the distribution of melanin and carotenoid in their plumages, respectively. Among species, sequence variation at ASIP broadly mirrors the species' phylogenetic history, consistent with repeated, independent mutations generating melanin-based variation. In contrast, BCO2 variation is highly discordant from the species tree, with evidence of cross-lineage introgression among species like the yellow warbler (Setophaga petechia) and magnolia warbler (S. magnolia) with extensive carotenoid-based coloration. We also detect introgression of a small part of the BCO2 coding region (<3 kb) in S. discolor and S. vitellina, including an amino acid substitution that is unique to warblers but otherwise highly conserved across birds. Lateral transfer of carotenoid-processing genes has been documented in arthropods, but introgression of BCO2 as demonstrated here-presumably adaptive-represents the first example of carotenoid gene transfer among vertebrates. These contrasting genomic patterns show that both independent evolution in a common set of genes and past hybridization have fueled plumage diversification in this colorful avian radiation.
Copyright © 2020 Elsevier Inc. All rights reserved.
Copyright © 2020 Elsevier Inc. All rights reserved.
Additional References
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
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