GEPHE SUMMARY Print
Entry Status
Published
GepheID
GP00002404
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait
Trait State in Taxon A
Bombyx mori - local strains
Trait State in Taxon B
Bombyx mori - domesticated strains
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
domestic silkworm
Synonyms
domestic silkworm; silk moth; silkworm; Bombyx mori Linnaeus, 1758
Rank
species
Lineage
Show more ... xapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Bombycoidea; Bombycidae; Bombycinae; Bombyx
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
domestic silkworm
Synonyms
domestic silkworm; silk moth; silkworm; Bombyx mori Linnaeus, 1758
Rank
species
Lineage
Show more ... xapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Bombycoidea; Bombycidae; Bombycinae; Bombyx
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
AsnS
Synonyms
AS; asparagine-synthetase; CG33486; Dmel\CG33486; CG33486-RA; Dmel_CG33486
Sequence Similarities
-
GO - Cellular Component
UniProtKB
Drosophila melanogaster
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Molecular Details of the Mutation
-
Experimental Evidence
Authors
Xiang H; Liu X; Li M; Zhu Y; Wang L; Cui Y; Liu L; Fang G; et al. ... show more
Abstract
The Silk Road, which derives its name from the trade of silk produced by the domestic silkworm Bombyx mori, was an important episode in the development and interaction of human civilizations. However, the detailed history behind silkworm domestication remains ambiguous, and little is known about the underlying genetics with respect to important aspects of its domestication. Here, we reconstruct the domestication processes and identify selective sweeps by sequencing 137 representative silkworm strains. The results present an evolutionary scenario in which silkworms may have been initially domesticated in China as trimoulting lines, then subjected to independent spreads along the Silk Road that gave rise to the development of most local strains, and further improved for modern silk production in Japan and China, having descended from diverse ancestral sources. We find that genes with key roles in nitrogen and amino acid metabolism may have contributed to the promotion of silk production, and that circadian-related genes are generally selected for their adaptation. We additionally identify associations between several candidate genes and important breeding traits, thereby advancing the applicable value of our resources.
EXTERNAL LINKS
COMMENTS
YOUR FEEDBACK is welcome!