GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00002485
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Helicoverpa zea - susceptible
Trait State in Taxon B
Helicoverpa zea - native species present in Brazil - resistant individuals
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
corn earworm
Synonyms
Heliothis zea; corn earworm; bollworm; tomato fruitworm; Helicoverpa zea (Boddie, 1850)
Rank
species
Lineage
Show more ... da; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Noctuoidea; Noctuidae; Heliothinae; Helicoverpa
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
corn earworm
Synonyms
Heliothis zea; corn earworm; bollworm; tomato fruitworm; Helicoverpa zea (Boddie, 1850)
Rank
species
Lineage
Show more ... da; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Amphiesmenoptera; Lepidoptera; Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Noctuoidea; Noctuidae; Heliothinae; Helicoverpa
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
UniProtKB
Helicoverpa armigera
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
Insertion Size
-
Molecular Details of the Mutation
Introgression of the CYP337B3v2 resistant allele from Helicoverpa armigera
Experimental Evidence
Authors
Walsh TK; Joussen N; Tian K; McGaughran A; Anderson CJ; Qiu X; Ahn SJ; Bird L; et al. ... show more
Abstract
The cotton bollworm, Helicoverpa armigera (Hübner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This species has evolved resistance to the pyrethroid insecticides across its native range and is becoming a truly global pest after establishing in South America and having been recently recorded in North America. A chimeric cytochrome P450 gene, CYP337B3, has been identified as a resistance mechanism for resistance to fenvalerate and cypermethrin. Here we show that this resistance mechanism is common around the world with at least eight different alleles. It is present in South America and has probably introgressed into its closely related native sibling species, Helicoverpa zea. The different alleles of CYP337B3 are likely to have arisen independently in different geographic locations from selection on existing diversity. The alleles found in Brazil are those most commonly found in Asia, suggesting a potential origin for the incursion of H. armigera into the Americas.
RELATED GEPHE
Related Genes
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
@Introgression - H. zea has been shown to interbreed with H. armigera in the laboratory to produce viable offspring. @SelectiveSweep
YOUR FEEDBACK is welcome!