GEPHE SUMMARY Print
Gephebase Gene
para (kdr)
Entry Status
Published
GepheID
GP00002523
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (insecticide)
Trait State in Taxon A
Anopheles subpictus - Sensitive to Pyrethroids
Trait State in Taxon B
Anopheles subpictus - Resistant to Pyrethroids
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Anopheles subpictus
Common Name
-
Synonyms
Anopheles subpictus Grassi, 1899
Rank
species
Lineage
Show more ... ea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Pyretophorus; subpictus species complex
Parent
subpictus species complex () - (Rank: no rank)
NCBI Taxonomy ID
59160
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Anopheles subpictus
Common Name
-
Synonyms
Anopheles subpictus Grassi, 1899
Rank
species
Lineage
Show more ... ea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Pyretophorus; subpictus species complex
Parent
subpictus species complex () - (Rank: no rank)
NCBI Taxonomy ID
59160
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
para
Synonyms
bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; sbl; sbl-1; Shu; Shudderer
String
7227.FBpp0303597
Sequence Similarities
Belongs to the sodium channel (TC 1.A.1.10) family. Para subfamily.
GO - Molecular Function
GO:0005509 : calcium ion binding ... show more
GO - Biological Process
GO:0045433 : male courtship behavior, veined wing generated song production ... show more
GO - Cellular Component
GO:0005887 : integral component of plasma membrane ... show more
UniProtKB
Drosophila melanogaster
P35500
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Coding
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
L1014F - TTA>TTT
Experimental Evidence
Candidate Gene
Taxon A Taxon B Position
Codon TTA TTT -
Amino-acid Leu Phe 1014
Main Reference
Mutated sodium channel genes and elevated monooxygenases are found in pyrethroid resistant populations of Sri Lankan malaria vectors . (2007 )
Authors
Karunaratne SHPP; Hawkes Nicola J; Perera MDB; Ranson Hilary; Hemingway Janet
Abstract
-
Additional References
Molecular biology of insect sodium channels and pyrethroid resistance. (2014)
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
@Parallelism
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