GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00002525
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Haematobia irritans exigua
Trait State in Taxon B
Haematobia irritans exigua - resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
-
Common Name
-
Synonyms
-
Rank
-
Lineage
-
Parent
-
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
-
Common Name
-
Synonyms
-
Rank
-
Lineage
-
Parent
-
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Presumptive Null
No
Molecular Type
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
L1014F
Experimental Evidence
Taxon A Taxon B Position
Codon - - -
Amino-acid - - -
Authors
Rothwell JT; Morgan JA; James PJ; Brown GW; Guerrero FD; Jorgensen WK
Abstract
Resistance to synthetic pyrethroids (SP) was first recorded in buffalo flies in Australia in 1980, associated with previous use of DDT and fenvalerate. By the 1990s, resistance was widespread. Resistance to SP in the related horn fly of the Americas is associated with kdr and super-kdr mutations in a gene encoding for a voltage-gated sodium channel. We describe 7-20-fold resistance to SP in buffalo flies from south-east Queensland, present evidence of flies that are heterozygous resistant at the kdr locus and show an increase in the frequency of the resistant allele 1 month after treatment of cattle with SP.

© 2011 The Authors. Australian Veterinary Journal © 2011 Australian Veterinary Association.
RELATED GEPHE
Related Genes
No matches found.
Related Haplotypes
No matches found.
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