GEPHE SUMMARY Print
Gephebase Gene
para (kdr)
Entry Status
Published
GepheID
GP00002541
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (insecticide)
Trait State in Taxon A
Blatella germanica
Trait State in Taxon B
Blatella germanica - resistant
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Blattella germanica
Common Name
German cockroach
Synonyms
German cockroach; Blattella germanica (Linnaeus, 1767); Blatella germanica
Rank
species
Lineage
Show more ... ysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blaberoidea; Ectobiidae; Blattellinae; Blattella
Parent
Blattella () - (Rank: genus)
NCBI Taxonomy ID
6973
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Blattella germanica
Common Name
German cockroach
Synonyms
German cockroach; Blattella germanica (Linnaeus, 1767); Blatella germanica
Rank
species
Lineage
Show more ... ysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blaberoidea; Ectobiidae; Blattellinae; Blattella
Parent
Blattella () - (Rank: genus)
NCBI Taxonomy ID
6973
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
para
Synonyms
bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; sbl; sbl-1; Shu; Shudderer
String
7227.FBpp0303597
Sequence Similarities
Belongs to the sodium channel (TC 1.A.1.10) family. Para subfamily.
GO - Molecular Function
GO:0005509 : calcium ion binding ... show more
GO - Biological Process
GO:0045433 : male courtship behavior, veined wing generated song production ... show more
GO - Cellular Component
GO:0005887 : integral component of plasma membrane ... show more
UniProtKB
Drosophila melanogaster
P35500
GenebankID or UniProtKB
AGW43268
Presumptive Null
No
Molecular Type
Coding
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
F999S = F1020S - T to C at nt 2996 resulting in a phenylalanine999 to serine999 amino acid change
Experimental Evidence
Candidate Gene
Taxon A Taxon B Position
Codon TTY TCY -
Amino-acid Phe Ser 1020
Main Reference
Variability of resistance mechanisms in pyrethroid resistant German cockroaches (Dictyoptera: Blattellidae) . (2002 )
Authors
Pridgeon Julia W; Appel Arthur G; Moar William J; Liu Nannan
Abstract
-
Additional References
Molecular biology of insect sodium channels and pyrethroid resistance. (2014)
RELATED GEPHE
Related Genes
1 (resistance to dieldrin)
Related Haplotypes
3
EXTERNAL LINKS
COMMENTS
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