GEPHE SUMMARY Print
Gephebase Gene
Acetylcholinesterase (Ace-2)
Entry Status
Published
GepheID
GP00002565
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (insecticide)
Trait State in Taxon A
Bemisia tabaci - sensitive
Trait State in Taxon B
Bemisia tabaci - resistant
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Bemisia tabaci
Common Name
-
Synonyms
Aleyrodes tabaci; sweet potato whitefly; Bemisia tabaci (Gennadius, 1889)
Rank
species
Lineage
Show more ... ozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aleyrodoidea; Aleyrodidae; Aleyrodinae; Bemisia
Parent
Bemisia () - (Rank: genus)
NCBI Taxonomy ID
7038
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Bemisia tabaci
Common Name
-
Synonyms
Aleyrodes tabaci; sweet potato whitefly; Bemisia tabaci (Gennadius, 1889)
Rank
species
Lineage
Show more ... ozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aleyrodoidea; Aleyrodidae; Aleyrodinae; Bemisia
Parent
Bemisia () - (Rank: genus)
NCBI Taxonomy ID
7038
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
Ace
Synonyms
AcChE; ace; ACE; ace-2; ache; AchE; AChE; CG17907; CHE; dAChE; dmAChE; DmAChE; Dmel\CG17907; Dm_ace; FBgn0000024; l(3)26; l(3)87Ed
String
7227.FBpp0289713
Sequence Similarities
Belongs to the type-B carboxylesterase/lipase family.
GO - Molecular Function
GO:0042803 : protein homodimerization activity ... show more
GO - Biological Process
GO:0006581 : acetylcholine catabolic process ... show more
GO - Cellular Component
GO:0005886 : plasma membrane ... show more
UniProtKB
Drosophila melanogaster
P07140
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Coding
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
Phe392Trp mutation located in the acyl pocket of the active site gorge and recently shown to confer OP insensitivity in Culex tritaeniorhynchus
Experimental Evidence
Candidate Gene
Taxon A Taxon B Position
Codon - - -
Amino-acid Phe Trp 392
Main Reference
Molecular analysis of cyclodiene resistance-associated mutations among populations of the sweetpotato whitefly Bemisia tabaci . (1995 )
Authors
Anthony NM; Brown JK; Markham PG; Ffrenchconstant RH
Abstract
-
Additional References
Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. (2015)
RELATED GEPHE
Related Genes
5 (acetyl-CoA carboxylase (ACC), Acetylcholinesterase (Ace-1), CYP6CM1, para (kdr), resistance to dieldrin)
Related Haplotypes
No matches found.
EXTERNAL LINKS
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