GEPHE SUMMARY Print
Gephebase Gene
Acetylcholinesterase (Ace-2)
Entry Status
Published
GepheID
GP00002569
Main curator
Courtier
PHENOTYPIC CHANGE
Trait Category
Physiology
Trait
Xenobiotic resistance (insecticide)
Trait State in Taxon A
Aphis gossypii - sensitive
Trait State in Taxon B
Aphis gossypii - resistant
Ancestral State
Taxon A
Taxonomic Status
Intraspecific
Taxon A
Latin Name
Aphis gossypii
Common Name
cotton aphid
Synonyms
cotton aphid; melon aphid; Aphis gossypii Glover, 1877; Aphis gossyppi
Rank
species
Lineage
Show more ... thropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha; Aphidoidea; Aphididae; Aphidinae; Aphidini; Aphis; Aphis
Parent
Aphis () - (Rank: subgenus)
NCBI Taxonomy ID
80765
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Aphis gossypii
Common Name
cotton aphid
Synonyms
cotton aphid; melon aphid; Aphis gossypii Glover, 1877; Aphis gossyppi
Rank
species
Lineage
Show more ... thropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha; Aphidoidea; Aphididae; Aphidinae; Aphidini; Aphis; Aphis
Parent
Aphis () - (Rank: subgenus)
NCBI Taxonomy ID
80765
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
Ace
Synonyms
AcChE; ace; ACE; ace-2; ache; AchE; AChE; CG17907; CHE; dAChE; dmAChE; DmAChE; Dmel\CG17907; Dm_ace; FBgn0000024; l(3)26; l(3)87Ed
String
7227.FBpp0289713
Sequence Similarities
Belongs to the type-B carboxylesterase/lipase family.
GO - Molecular Function
GO:0042803 : protein homodimerization activity ... show more
GO - Biological Process
GO:0006581 : acetylcholine catabolic process ... show more
GO - Cellular Component
GO:0005886 : plasma membrane ... show more
UniProtKB
Drosophila melanogaster
P07140
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Coding
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
F78L
Experimental Evidence
Candidate Gene
Taxon A Taxon B Position
Codon - - -
Amino-acid Phe Leu 78
Main Reference
Mutations in acetylcholinesterase associated with insecticide resistance in the cotton aphid, Aphis gossypii Glover . (2004 )
Authors
Li Fei; Han Zhaojun
Abstract
-
Additional References
Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. (2015)
RELATED GEPHE
Related Genes
3 (Acetylcholinesterase (Ace-1), nAChR, para (kdr))
Related Haplotypes
No matches found.
EXTERNAL LINKS
COMMENTS
YOUR FEEDBACK is welcome!