GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00000275
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Columba livia - No crest (dominant)
Trait State in Taxon B
Columba livia - Crest (recessive)
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Latin Name
Common Name
rock pigeon
Synonyms
Columba livia domestica; rock pigeon; carrier pigeon; domestic pigeon; rock dove; Columba livia Gmelin, JF, 1789
Rank
species
Lineage
Show more ... erygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Latin Name
Common Name
rock pigeon
Synonyms
Columba livia domestica; rock pigeon; carrier pigeon; domestic pigeon; rock dove; Columba livia Gmelin, JF, 1789
Rank
species
Lineage
Show more ... erygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Generic Gene Name
EPHB2
Synonyms
CEK5
Sequence Similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
UniProtKB
Gallus gallus
GenebankID or UniProtKB
Presumptive Null
No
Molecular Type
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
Arg758Cys (C>T)
Experimental Evidence
Taxon A Taxon B Position
Codon - - -
Amino-acid - - -
Authors
Shapiro MD; Kronenberg Z; Li C; Domyan ET; Pan H; Campbell M; Tan H; Huff CD; et al. ... show more
Abstract
The geographic origins of breeds and the genetic basis of variation within the widely distributed and phenotypically diverse domestic rock pigeon (Columba livia) remain largely unknown. We generated a rock pigeon reference genome and additional genome sequences representing domestic and feral populations. We found evidence for the origins of major breed groups in the Middle East and contributions from a racing breed to North American feral populations. We identified the gene EphB2 as a strong candidate for the derived head crest phenotype shared by numerous breeds, an important trait in mate selection in many avian species. We also found evidence that this trait evolved just once and spread throughout the species, and that the crest originates early in development by the localized molecular reversal of feather bud polarity.
RELATED GEPHE
Related Haplotypes
No matches found.
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