GEPHE SUMMARY Print
Gephebase Gene
Entry Status
Published
GepheID
GP00000841
Main curator
Martin
PHENOTYPIC CHANGE
Trait Category
Trait State in Taxon A
Leptinotarsa decemlineata
Trait State in Taxon B
Leptinotarsa decemlineata - resistant
Ancestral State
Taxon A
Taxonomic Status
Taxon A
Common Name
Colorado potato beetle
Synonyms
Leptinotarsa decimlineata; Stilodes decemlineata; Colorado potato beetle; Leptinotarsa decemlineata (Say, 1824)
Rank
species
Lineage
Show more ... andibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Chrysomeloidea; Chrysomelidae; Chrysomelinae; Doryphorini; Leptinotarsa
NCBI Taxonomy ID
is Taxon A an Infraspecies?
No
Taxon B
Common Name
Colorado potato beetle
Synonyms
Leptinotarsa decimlineata; Stilodes decemlineata; Colorado potato beetle; Leptinotarsa decemlineata (Say, 1824)
Rank
species
Lineage
Show more ... andibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Chrysomeloidea; Chrysomelidae; Chrysomelinae; Doryphorini; Leptinotarsa
NCBI Taxonomy ID
is Taxon B an Infraspecies?
No
GENOTYPIC CHANGE
Presumptive Null
No
Molecular Type
Aberration Type
SNP
SNP Coding Change
Nonsynonymous
Molecular Details of the Mutation
L1014H
Experimental Evidence
Taxon A Taxon B Position
Codon - - -
Amino-acid - - -
Authors
Rinkevich FD; Du Y; Dong K
Abstract
Pyrethroid insecticides target voltage-gated sodium channels, which are critical for electrical signaling in the nervous system. The intensive use of pyrethroids in controlling arthropod pests and disease vectors has led to many instances of pyrethroid resistance around the globe. In the past two decades, studies have identified a large number of sodium channel mutations that are associated with resistance to pyrethroids. The purpose of this review is to summarize both common and unique sodium channel mutations that have been identified in arthropod pests of importance to agriculture or human health. Identification of these mutations provides valuable molecular markers for resistance monitoring in the field and helped the discovery of the elusive pyrethroid receptor site(s) on the sodium channel.
Additional References
RELATED GEPHE
Related Haplotypes
No matches found.
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