Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 5 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
Prdm9	Hybrid incompatibility (F1 male sterility) Recombination rate (use of recombination hotspots)	Unknown, Unknown	Mus musculus house mouse - (species)	Intraspecific	Linkage Mapping	Mihola O; Trachtulec Z; Vlcek C ; et al. (2009) A mouse speciation gene encodes a meiotic histone H3 methyltransferase. 2 Additional References Baudat F; Buard J; Grey C (2010) PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Flachs P; Mihola O; Simeček P (2012) Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility.	GP00000922	Prdm9 Q96EQ9	Physiology Physiology	possible dosage difference (number of gene copies) interacting with an allele that affects post-transcriptional stability	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Prdm9	Mus musculus house mouse - (species)	Published - Accepted by Curator
Prdm9	Recombination rate (use of recombination hotspots)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Berg IL; Neumann R; Sarbajna S ; et al. (2011) Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots [...]	GP00000923	Prdm9 Q96EQ9	Physiology	Various haplotypes	Homo sapiens human - (species)	Homo sapiens human - (species)	Prdm9	Homo sapiens human - (species)	Published - Accepted by Curator
PRDM9	Recombination rate (male)	Coding, Deletion	Bos taurus cattle - (species)	Domesticated	Linkage Mapping	Sandor C; Li W; Coppieters W ; et al. (2012) Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.	GP00001640	PRDM9 A6QNW2	Physiology	variation in the C-terminal tandem array of Cys2His2 zinc-finger domains: 22 domains > 20 domains decreasing 6-fold Genome wide hot window usage in Crossing Over	Bos taurus cattle - (species)	Bos taurus cattle - (species)	PRDM9	Bos taurus cattle - (species)	Published - Accepted by Curator
PRDM9	Recombination rate (male)	Coding, SNP	Bos taurus cattle - (species)	Domesticated	Linkage Mapping	Sandor C; Li W; Coppieters W ; et al. (2012) Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.	GP00001641	PRDM9 A6QNW2	Physiology	variation in the C-terminal tandem array of Cys2His2 zinc-finger domains: T68A p.I23K in domain 11 has a major effect. K allele decreasing 30-fold Genome wide hot window usage in Crossing Over compared to I allele	Bos taurus cattle - (species)	Bos taurus cattle - (species)	PRDM9	Bos taurus cattle - (species)	Published - Accepted by Curator
PRDM9	Recombination rate (male)	Coding, SNP	Bos taurus cattle - (species)	Domesticated	Linkage Mapping	Sandor C; Li W; Coppieters W ; et al. (2012) Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.	GP00001642	PRDM9 A6QNW2	Physiology	variation in the C-terminal tandem array of Cys2His2 zinc-finger domains: T20C p.A>Y sustitutions in domains 14. Y allele increasing 6-fold Genome wide hot window usage in Crossing Over	Bos taurus cattle - (species)	Bos taurus cattle - (species)	PRDM9	Bos taurus cattle - (species)	Published - Accepted by Curator