Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 9 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
Ir75a	Olfaction	Coding, SNP	Drosophila sechellia (species) D	Interspecific	Candidate Gene	Prieto-Godino LL; Rytz R; Bargeton B ; et al. (2016) Olfactory receptor pseudo-pseudogenes.	GP00001701	Ir75a Q9VVL1	Physiology	T289S and/or Q536K and/or F538L - introduction of these three amino acid changes in the D. melanogaster protein is sufficient to confer response indistinguishable from the one of D. sechellia	Drosophila melanogaster fruit fly - (species)	Drosophila sechellia (species) D	Ir75a	Drosophila sechellia (species)	Published - Accepted by Curator
Ir75b	Olfaction	Coding, SNP	Drosophila sechellia (species) D	Interspecific	Candidate Gene	Prieto-Godino LL; Rytz R; Cruchet S ; et al. (2017) Evolution of Acid-Sensing Olfactory Circuits in Drosophilids.	GP00001702	Ir75b B7Z069	Physiology	T523S in the LBD domain - caused by C1568G	Drosophila melanogaster fruit fly - (species)	Drosophila sechellia (species) D	Ir75b	Drosophila sechellia (species)	Published - Accepted by Curator
Or22a	Olfaction	Coding, SNP	Drosophila sechellia (species) D Drosophila simulans (species) D Drosophila mauritiana (species) D	Interspecific	Candidate Gene	Auer TO; Khallaf MA; Silbering AF ; et al. (2020) Olfactory receptor and circuit evolution promote host specialization.	GP00002183	Or22a P81909	Physiology	Effect of the mutation tested in a Or22a construct which rescues the Or22a knock-down mutation in D. melanogaster.There are two other amino acid changes that may have an effect as well.	Drosophila melanogaster fruit fly - (species)	Drosophila sechellia (species) D Drosophila simulans (species) D Drosophila mauritiana (species) D	Or22a	Drosophila sechellia (species) Drosophila simulans (species) Drosophila mauritiana (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Keller A; Zhuang H; Chi Q ; et al. (2007) Genetic variation in a human odorant receptor alters odour perception. 1 Additional References Zhuang H; Chien MS; Matsunami H (2009) Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates.	GP00000799	OR7D4 Q8NG98	Physiology	P79L	Homo sapiens human - (species)	Homo sapiens human - (species)	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Keller A; Zhuang H; Chi Q ; et al. (2007) Genetic variation in a human odorant receptor alters odour perception.	GP00000800	OR7D4 Q8NG98	Physiology	R227G	Homo sapiens human - (species)	Homo sapiens human - (species)	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Keller A; Zhuang H; Chi Q ; et al. (2007) Genetic variation in a human odorant receptor alters odour perception.	GP00000801	OR7D4 Q8NG98	Physiology	T133M	Homo sapiens human - (species)	Homo sapiens human - (species)	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Keller A; Zhuang H; Chi Q ; et al. (2007) Genetic variation in a human odorant receptor alters odour perception.	GP00000802	OR7D4 Q8NG98	Physiology	S84N	Homo sapiens human - (species)	Homo sapiens human - (species)	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species) D	Interspecific	Candidate Gene	Keller A; Zhuang H; Chi Q ; et al. (2007) Genetic variation in a human odorant receptor alters odour perception. 1 Additional References Zhuang H; Chien MS; Matsunami H (2009) Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates.	GP00000803	OR7D4 Q8NG98	Physiology	R227G	Homininae (subfamily)	Homo sapiens human - (species) D	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator
OR7D4	Olfaction	Coding, SNP	Homo sapiens human - (species) D	Interspecific	Candidate Gene	Zhuang H; Chien MS; Matsunami H (2009) Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates.	GP00000804	OR7D4 Q8NG98	Physiology	M273T	Homininae (subfamily)	Homo sapiens human - (species) D	OR7D4	Homo sapiens human - (species)	Published - Accepted by Curator