Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 26 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Mya arenaria (species) D	Intraspecific	Candidate Gene	Bricelj VM; Connell L; Konoki K ; et al. (2005) Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP.	GP00000721	SCN4A P35499	Physiology	E945D	Mya arenaria (species)	Mya arenaria (species) D	SCN4A (Nav1.4)	Mya arenaria (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Erythrolamprus epinephelus (species) D	Interspecific	Candidate Gene	McGlothlin JW; Kobiela ME; Feldman CR ; et al. (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. 1 Additional References Feldman CR; Brodie ED; Brodie ED (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes.	GP00000724	SCN4A P35499	Physiology	G1569D in DIV domain and D1568S in DIV domain with D1568S supposed to increase the resistance - exact causing mutation(s) unknown	Erythrolamprus poecilogyrus (species)	Erythrolamprus epinephelus (species) D	SCN4A (Nav1.4)	Erythrolamprus epinephelus (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Rhabdophis tigrinus Tiger keelback - (species) D	Interspecific	Candidate Gene	Feldman CR; Brodie ED; Brodie ED ; et al. (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes. 1 Additional References McGlothlin JW; Kobiela ME; Feldman CR (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance.	GP00000725	SCN4A P35499	Physiology	I1555M	Thamnophis elegans Western terrestrial garter snake - (species)	Rhabdophis tigrinus Tiger keelback - (species) D	SCN4A (Nav1.4)	Rhabdophis tigrinus Tiger keelback - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis atratus (species) D	Interspecific	Candidate Gene	McGlothlin JW; Kobiela ME; Feldman CR ; et al. (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. 1 Additional References Feldman CR; Brodie ED; Brodie ED (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes.	GP00000726	SCN4A P35499	Physiology	D1277E in DIII domain	Thamnophis couchii (species)	Thamnophis atratus (species) D	SCN4A (Nav1.4)	Thamnophis atratus (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis atratus (species) D	Interspecific	Candidate Gene	McGlothlin JW; Kobiela ME; Feldman CR ; et al. (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. 1 Additional References Feldman CR; Brodie ED; Brodie ED (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes.	GP00000727	SCN4A P35499	Physiology	D1568N in DIV domain	Thamnophis couchii (species)	Thamnophis atratus (species) D	SCN4A (Nav1.4)	Thamnophis atratus (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis couchii (species) D	Interspecific	Candidate Gene	McGlothlin JW; Kobiela ME; Feldman CR ; et al. (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. 1 Additional References Feldman CR; Brodie ED; Brodie ED (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes.	GP00000728	SCN4A P35499	Physiology	M1276T in DIII domain	Thamnophis atratus (species)	Thamnophis couchii (species) D	SCN4A (Nav1.4)	Thamnophis couchii (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Hebius pryeri Pryer's keelback - (species) D	Interspecific	Candidate Gene	Feldman CR; Brodie ED; Brodie ED ; et al. (2012) Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes. 1 Additional References McGlothlin JW; Kobiela ME; Feldman CR (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance.	GP00000729	SCN4A P35499	Physiology	D1227E = D945E in DIII domain	Hebius vibakari Japanese keelback - (species)	Hebius pryeri Pryer's keelback - (species) D	SCN4A (Nav1.4)	Hebius pryeri Pryer's keelback - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis sirtalis (species)	Intraspecific	Candidate Gene	Geffeney SL; Fujimoto E; Brodie ED ; et al. (2005) Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction. 1 Additional References McGlothlin JW; Kobiela ME; Feldman CR (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance.	GP00000730	SCN4A P35499	Physiology	G1566A in DIV domain	Thamnophis sirtalis (species)	Thamnophis sirtalis (species)	SCN4A (Nav1.4)	Thamnophis sirtalis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis sirtalis (species)	Intraspecific	Candidate Gene	Geffeney SL; Fujimoto E; Brodie ED ; et al. (2005) Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction. 1 Additional References McGlothlin JW; Kobiela ME; Feldman CR (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance.	GP00000731	SCN4A P35499	Physiology	I1561V in DIV domain	Thamnophis sirtalis (species)	Thamnophis sirtalis (species)	SCN4A (Nav1.4)	Thamnophis sirtalis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (TTX)	Coding, SNP	Thamnophis sirtalis (species)	Intraspecific	Candidate Gene	Geffeney SL; Fujimoto E; Brodie ED ; et al. (2005) Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction. 1 Additional References McGlothlin JW; Kobiela ME; Feldman CR (2016) Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance.	GP00000732	SCN4A P35499	Physiology	I1556L and/or D1568N and/or G1569V	Thamnophis sirtalis (species)	Thamnophis sirtalis (species)	SCN4A (Nav1.4)	Thamnophis sirtalis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Mantella aurantiaca (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001573	SCN4A P35499	Physiology	C>A p.A446D in DI-S6 domain	Anura frogs and toads - (order)	Mantella aurantiaca (species) D	SCN4A (Nav1.4)	Mantella aurantiaca (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Phyllobates terribilis (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001574	SCN4A P35499	Physiology	T>G p.S429A in DI-S6 domain	Anura frogs and toads - (order)	Phyllobates terribilis (species) D	SCN4A (Nav1.4)	Phyllobates terribilis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Phyllobates terribilis (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001575	SCN4A P35499	Physiology	A>G p.I433V in DI-S6 domain	Anura frogs and toads - (order)	Phyllobates terribilis (species) D	SCN4A (Nav1.4)	Phyllobates terribilis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Dendrobates tinctorius dyeing poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001576	SCN4A P35499	Physiology	A>G p.I433V in DI-S6 domain	Anura frogs and toads - (order)	Dendrobates tinctorius dyeing poison frog - (species) D	SCN4A (Nav1.4)	Dendrobates tinctorius dyeing poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Excidobates captivus Rio Santiago poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001577	SCN4A P35499	Physiology	A>G p.I433V in DI-S6 domain	Anura frogs and toads - (order)	Excidobates captivus Rio Santiago poison frog - (species) D	SCN4A (Nav1.4)	Excidobates captivus Rio Santiago poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Phyllobates terribilis (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001578	SCN4A P35499	Physiology	C>A p.A446D in DI-S6 domain	Anura frogs and toads - (order)	Phyllobates terribilis (species) D	SCN4A (Nav1.4)	Phyllobates terribilis (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Dendrobates tinctorius dyeing poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001579	SCN4A P35499	Physiology	C>A p.A446D in DI-S6 domain	Anura frogs and toads - (order)	Dendrobates tinctorius dyeing poison frog - (species) D	SCN4A (Nav1.4)	Dendrobates tinctorius dyeing poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Excidobates captivus Rio Santiago poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001580	SCN4A P35499	Physiology	CC>AA p.A446E in DI-S6 domain	Anura frogs and toads - (order)	Excidobates captivus Rio Santiago poison frog - (species) D	SCN4A (Nav1.4)	Excidobates captivus Rio Santiago poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Ameerega parvula ruby poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001581	SCN4A P35499	Physiology	C>A p.A446D in DI-S6 domain	Anura frogs and toads - (order)	Ameerega parvula ruby poison frog - (species) D	SCN4A (Nav1.4)	Ameerega parvula ruby poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Epipedobates phantasmal poison frogs - (genus) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001582	SCN4A P35499	Physiology	C>A p.A446D in DI-S6 domain	Anura frogs and toads - (order)	Epipedobates phantasmal poison frogs - (genus) D	SCN4A (Nav1.4)	Epipedobates phantasmal poison frogs - (genus)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Phyllobates (genus) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001583	SCN4A P35499	Physiology	G>A p.V1583I in DIV-S6 domain	Anura frogs and toads - (order)	Phyllobates (genus) D	SCN4A (Nav1.4)	Phyllobates (genus)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Dendrobates tinctorius dyeing poison frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001584	SCN4A P35499	Physiology	G>A p.V1583I in DIV-S6 domain	Anura frogs and toads - (order)	Dendrobates tinctorius dyeing poison frog - (species) D	SCN4A (Nav1.4)	Dendrobates tinctorius dyeing poison frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Hyloxalus italoi (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001585	SCN4A P35499	Physiology	G>A p.V1583I in DIV-S6 domain	Anura frogs and toads - (order)	Hyloxalus italoi (species) D	SCN4A (Nav1.4)	Hyloxalus italoi (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Ameerega (genus) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001586	SCN4A P35499	Physiology	G>A p.V1583I in DIV-S6 domain	Anura frogs and toads - (order)	Ameerega (genus) D	SCN4A (Nav1.4)	Ameerega (genus)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Silverstoneia flotator rainforest rocket frog - (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001587	SCN4A P35499	Physiology	G>A p.V1583I in DIV-S6 domain	Anura frogs and toads - (order)	Silverstoneia flotator rainforest rocket frog - (species) D	SCN4A (Nav1.4)	Silverstoneia flotator rainforest rocket frog - (species)	Published - Accepted by Curator
SCN4A (Nav1.4)	Xenobiotic resistance (poison frog alkaloids)	Coding, SNP	Phyllobates terribilis (species) D	Intergeneric or Higher	Candidate Gene	Tarvin RD; Santos JC; O'Connell LA ; et al. (2016) Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison [...]	GP00001588	SCN4A P35499	Physiology	C>A p.N1584T in DIV-S6 domain	Anura frogs and toads - (order)	Phyllobates terribilis (species) D	SCN4A (Nav1.4)	Phyllobates terribilis (species)	Published - Accepted by Curator