Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

Advanced Search

Field

Term

Summary Table

Your research retrieved 12 results.

Summary
Others

Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Aphis gossypii cotton aphid - (species) D	Intraspecific	Candidate Gene	Wang ZJ; Liang CR; Shang ZY ; et al. (2021) Insecticide resistance and resistance mechanisms in the melon aphid, Aphis gossypii, in Shandong, Ch[...]	GP00002491	nAChRbeta1 P04755	Physiology	R81T	Aphis gossypii cotton aphid - (species)	Aphis gossypii cotton aphid - (species) D	nAChR	Aphis gossypii cotton aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Aphis gossypii cotton aphid - (species) D	Intraspecific	Candidate Gene	Wang ZJ; Liang CR; Shang ZY ; et al. (2021) Insecticide resistance and resistance mechanisms in the melon aphid, Aphis gossypii, in Shandong, Ch[...]	GP00002492	nAChRbeta1 P04755	Physiology	K264E	Aphis gossypii cotton aphid - (species)	Aphis gossypii cotton aphid - (species) D	nAChR	Aphis gossypii cotton aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Bass C; Puinean AM; Andrews M ; et al. (2011) Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotin[...] 2 Additional References Feyereisen R; Dermauw W; Van Leeuwen T (2015) Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. Singh KS; Cordeiro EMG; Troczka BJ (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...]	GP00002553	nAChRbeta1 P04755	Physiology	R81T in the loop D region of the nAChR β1 subunit of the resistant clone	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	nAChR	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad; spirotetramat)	Coding, SNP	Frankliniella occidentalis western flower thrips - (species) D	Intraspecific	Candidate Gene	Puinean AM; Lansdell SJ; Collins T ; et al. (2013) A nicotinic acetylcholine receptor transmembrane point mutation (G275E) associated with resistance t[...] 3 Additional References Feyereisen R; Dermauw W; Van Leeuwen T (2015) Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. Sun LN; Shen XJ; Cao LJ (2022) Increasing Frequency of G275E Mutation in the Nicotinic Acetylcholine Receptor α6 Subunit Conferring[...] Zimmer CT; Garrood WT; Puinean AM (2016) A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor[...]	GP00002554	nAChRbeta1 P04755	Physiology	G275E in nAchR alpha 6 due to a single nucleotide change	Frankliniella occidentalis western flower thrips - (species)	Frankliniella occidentalis western flower thrips - (species) D	nAChR	Frankliniella occidentalis western flower thrips - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Thrips palmi (species) D	Intraspecific	Candidate Gene	Bao WX; Narai Y; Nakano A ; et al. (2014) Spinosad resistance of melon thrips, Thrips palmi, is conferred by G275E mutation in α6 subunit of n[...] 1 Additional References Feyereisen R; Dermauw W; Van Leeuwen T (2015) Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods.	GP00002555	nAChRbeta1 P04755	Physiology	G275E in nAchR alpha 6 due to a single nucleotide change	Thrips palmi (species)	Thrips palmi (species) D	nAChR	Thrips palmi (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Xu X; Ding Q; Wang X ; et al. (2022) V101I and R81T mutations in the nicotinic acetylcholine receptor β1 subunit are associated with neon[...]	GP00002612	nAChRbeta1 P04755	Physiology	V101I	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	nAChR	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, SNP	Tuta absoluta (species) D	Intraspecific	Candidate Gene	Silva WM; Berger M; Bass C ; et al. (2016) Mutation (G275E) of the nicotinic acetylcholine receptor α6 subunit is associated with high levels o[...] 1 Additional References Zimmer CT; Garrood WT; Puinean AM (2016) A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor[...]	GP00002621	nAChRbeta1 P04755	Physiology	G275E in nAchR alpha 6 due to a single nucleotide change	Tuta absoluta (species)	Tuta absoluta (species) D	nAChR	Tuta absoluta (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, Unknown N	Bactrocera dorsalis oriental fruit fly - (species) D	Intraspecific	Candidate Gene	Hsu JC; Feng HT; Wu WJ ; et al. (2012) Truncated transcripts of nicotinic acetylcholine subunit gene Bdα6 are associated with spinosad resi[...]	GP00002650	CHRNA6 Q15825	Physiology	Mutation in Bdα6 intron 2 (A change to T) just before the truncated/mis-splicing region and in same location with a mutation previously reported in the Pxylα6 gene. Small deletions and insertions leading to premature stop codons in exon 7. N	Bactrocera dorsalis oriental fruit fly - (species)	Bactrocera dorsalis oriental fruit fly - (species) D	nAChR	Bactrocera dorsalis oriental fruit fly - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, SNP N	Plutella xylostella diamondback moth - (species) D	Intraspecific	Linkage Mapping	Baxter SW; Chen M; Dawson A ; et al. (2010) Mis-spliced transcripts of nicotinic acetylcholine receptor alpha6 are associated with field evolved[...]	GP00002651	CHRNA6 Q15825	Physiology	A mutation within the ninth intron splice junction of Pxalpha6 results in mis-splicing of transcripts and produce a predicted protein truncated between the third and fourth transmembrane domains. N	Plutella xylostella diamondback moth - (species)	Plutella xylostella diamondback moth - (species) D	nAChR	Plutella xylostella diamondback moth - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, Deletion N	Plutella xylostella diamondback moth - (species) D	Intraspecific	Candidate Gene	Rinkevich FD; Chen M; Shelton AM ; et al. (2010) Transcripts of the nicotinic acetylcholine receptor subunit gene Pxylα6 with premature stop codons a[...]	GP00002652	CHRNA6 Q15825	Physiology	transcripts with premature stop codons N	Plutella xylostella diamondback moth - (species)	Plutella xylostella diamondback moth - (species) D	nAChR	Plutella xylostella diamondback moth - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, Deletion N	Plutella xylostella diamondback moth - (species) D	Experimental Evolution	Candidate Gene	Wang J; Wang X; Lansdell SJ ; et al. (2016) A three amino acid deletion in the transmembrane domain of the nicotinic acetylcholine receptor α6 s[...]	GP00002653	CHRNA6 Q15825	Physiology	a three amino acid (3-aa) deletion in the fourth transmembrane domain (TM4) of the nAChR α6 subunit N	Plutella xylostella diamondback moth - (species)	Plutella xylostella diamondback moth - (species) D	nAChR	Plutella xylostella diamondback moth - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide; spinosad)	Coding, Deletion N	Rhyzopertha dominica lesser grain borer - (species) D	Intraspecific	Candidate Gene	Wang HT; Tsai CL; Chen ME (2018) Nicotinic acetylcholine receptor subunit α6 associated with spinosad resistance in Rhyzopertha domin[...]	GP00002654	CHRNA6 Q15825	Physiology	Three mutations were found in the resistant strain compared with the susceptible one: (1) a 181-bp fragment truncated at the N-terminus resulting in the appearance of a premature stop codon - (2) one missing bp at the position 997 causing a frame-shift mutation and (3) an 87-bp fragment truncated in the TM2 region. N	Rhyzopertha dominica lesser grain borer - (species)	Rhyzopertha dominica lesser grain borer - (species) D	nAChR	Rhyzopertha dominica lesser grain borer - (species)	Published - Accepted by Curator