Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 17 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
acetyl-CoA carboxylase (ACC)	Xenobiotic resistance (insecticide; spirotetramat)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Singh KS; Cordeiro EMG; Troczka BJ ; et al. (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...]	GP00002616	ACC Q7JV23	Physiology	a single non-synonymous mutation (gCt > gTt) resulting in an alanine to valine substitution in a highly conserved region of the ACC carboxyltransferase (CT) domain	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	acetyl-CoA carboxylase (ACC)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
Acetylcholinesterase (Ace-1)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Nabeshima T; Kozaki T; Tomita T ; et al. (2003) An amino acid substitution on the second acetylcholinesterase in the pirimicarb-resistant strains of[...]	GP00002015	Ace P07140	Physiology	Ser431Phe (position 331 in mature Torpedo protein)	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	Acetylcholinesterase (Ace-1)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
CYP6CY3	Xenobiotic resistance (insecticide; neonicotinoid; host plant)	Cis-regulatory, Insertion	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Bass C; Zimmer CT; Riveron JM ; et al. (2013) Gene amplification and microsatellite polymorphism underlie a recent insect host shift. 1 Additional References Bass C; Zimmer CT; Riveron JM (2013) Gene amplification and microsatellite polymorphism underlie a recent insect host shift.	GP00001474	CYP6CY3 V5SQ25	Physiology	Expansion of a AC dinucleotide microsatellite (from 15 to 48 repeat units) in the promoter 198 bp upstream of the start codon that enhances gene expression	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	CYP6CY3	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
CYP6CY3-CYP6CY4	Xenobiotic resistance (insecticide; neonicotinoid; host plant)	Gene Amplification, Insertion	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Bass C; Zimmer CT; Riveron JM ; et al. (2013) Gene amplification and microsatellite polymorphism underlie a recent insect host shift. 3 Additional References Puinean AM; Foster SP; Oliphant L (2010) Amplification of a cytochrome P450 gene is associated with resistance to neonicotinoid insecticides [...] Bass C; Zimmer CT; Riveron JM (2013) Gene amplification and microsatellite polymorphism underlie a recent insect host shift. Singh KS; Troczka BJ; Duarte A (2020) The genetic architecture of a host shift: An adaptive walk protected an aphid and its endosymbiont f[...]	GP00001473	CYP6CY3 V5SQ25	Physiology	gene amplification (from 2 to 14-100 copies) - CYP6CY3 and neighboring gene CYP6CY4 are duplicated in M. p. nicotianae as a large amplicon of ~325 kb creating characteristic breakpoints identifying the region. CYP6CY4 and CYP6CY3 are highly effective at metabolizing nicotine to its nontoxic metabolite cotinine.	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	CYP6CY3-CYP6CY4	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
esterase E4	Xenobiotic resistance (insecticide)	Gene Amplification, Complex Change	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Field LM; Devonshire AL; Forde BG (1988) Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results[...] 2 Additional References Field LM; Blackman RL; Tyler-Smith C (1999) Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae[...] Bass C; Puinean AM; Zimmer CT (2014) The evolution of insecticide resistance in the peach potato aphid, Myzus persicae.	GP00000293	P35501	Physiology	Whole gene amplification. Amplification of the E4 gene is closely linked to a chromosomal translocation (the autosomal 1-3 translocation event) and amplified genes are situated at a single heterozygous site on autosome 3 as a tandem array of head-to-tail amplicons.	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	esterase E4	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
esterase FE4	Xenobiotic resistance (insecticide)	Gene Amplification, Insertion	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Blackman RL; Spence JM; Field LM ; et al. (1999 ) Variation in the chromosomal distribution of amplified esterase (FE4) genes in Greek field populatio[...] 2 Additional References Field LM; Blackman RL; Tyler-Smith C (1999) Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae[...] Bass C; Puinean AM; Zimmer CT (2014) The evolution of insecticide resistance in the peach potato aphid, Myzus persicae.	GP00002642	P35502	Physiology	Gene amplification	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	esterase FE4	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Bass C; Puinean AM; Andrews M ; et al. (2011) Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotin[...] 2 Additional References Feyereisen R; Dermauw W; Van Leeuwen T (2015) Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. Singh KS; Cordeiro EMG; Troczka BJ (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...]	GP00002553	nAChRbeta1 P04755	Physiology	R81T in the loop D region of the nAChR β1 subunit of the resistant clone	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	nAChR	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
nAChR	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Xu X; Ding Q; Wang X ; et al. (2022) V101I and R81T mutations in the nicotinic acetylcholine receptor β1 subunit are associated with neon[...]	GP00002612	nAChRbeta1 P04755	Physiology	V101I	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	nAChR	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Linkage Mapping	Martinez-Torres D; Foster SP; Field LM ; et al. (1999) A sodium channel point mutation is associated with resistance to DDT and pyrethroid insecticides in [...]	GP00000844	para P35500	Physiology	L1014F	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Anstead JA; Williamson MS; Eleftherianos I ; et al. (2004) High-throughput detection of knockdown resistance in Myzus persicae using allelic discriminating qua[...]	GP00000845	para P35500	Physiology	(=M918T)	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Panini M; Anaclerio M; Puggioni V ; et al. (2015) Presence and impact of allelic variations of two alternative s-kdr mutations, M918T and M918L, in th[...] 3 Additional References Panini M; Dradi D; Marani G (2014) Detecting the presence of target-site resistance to neonicotinoids and pyrethroids in Italian popula[...] Singh KS; Cordeiro EMG; Troczka BJ (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...] Fontaine S; Caddoux L; Brazier C (2011) Uncommon associations in target resistance among French populations of Myzus persicae from oilseed r[...]	GP00001865	para P35500	Physiology	M918L	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Panini M; Anaclerio M; Puggioni V ; et al. (2015) Presence and impact of allelic variations of two alternative s-kdr mutations, M918T and M918L, in th[...] 1 Additional References Panini M; Dradi D; Marani G (2014) Detecting the presence of target-site resistance to neonicotinoids and pyrethroids in Italian popula[...]	GP00001866	para P35500	Physiology	M918L	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Cassanelli S; Cerchiari B; Giannini S ; et al. (2005) Use of the RFLP-PCR diagnostic test for characterizing MACE and kdr insecticide resistance in the pe[...] 1 Additional References Dong K; Du Y; Rinkevich F (2014) Molecular biology of insect sodium channels and pyrethroid resistance.	GP00002528	para P35500	Physiology	F979S (housefly numbering) located inside the linker segment IIS5-6	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Singh KS; Cordeiro EMG; Troczka BJ ; et al. (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...] 1 Additional References Vais H; Williamson MS; Devonshire AL (2001) The molecular interactions of pyrethroid insecticides with insect and mammalian sodium channels.	GP00002614	para P35500	Physiology	M918I ATG>ATT	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Singh KS; Cordeiro EMG; Troczka BJ ; et al. (2021) Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aph[...] 1 Additional References Vais H; Williamson MS; Devonshire AL (2001) The molecular interactions of pyrethroid insecticides with insect and mammalian sodium channels.	GP00002615	para P35500	Physiology	M918I ATG>ATA	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
para (kdr)	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Fontaine S; Caddoux L; Brazier C ; et al. (2011) Uncommon associations in target resistance among French populations of Myzus persicae from oilseed r[...] 1 Additional References Bass C; Puinean AM; Zimmer CT (2014) The evolution of insecticide resistance in the peach potato aphid, Myzus persicae.	GP00002649	para P35500	Physiology	L932F	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	para (kdr)	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator
resistance to dieldrin	Xenobiotic resistance (insecticide)	Coding, SNP	Myzus persicae green peach aphid - (species) D	Intraspecific	Candidate Gene	Anthony N; Unruh T; Ganser D ; et al. (1998) Duplication of the Rdl GABA receptor subunit gene in an insecticide-resistant aphid, Myzus persicae.	GP00000979	Rdl P25123	Physiology	Ala302Gly	Myzus persicae green peach aphid - (species)	Myzus persicae green peach aphid - (species) D	resistance to dieldrin	Myzus persicae green peach aphid - (species)	Published - Accepted by Curator