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Your research retrieved 73 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
18-wheeler	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00000001	18w A1ZBR2	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	18-wheeler	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Cf-4/9	Pathogen resistance	Gene Loss, Complex Change	Solanum lycopersicum tomato - (species)	Domesticated	Linkage Mapping	Parniske M; Hammond-Kosack KE; Golstein C ; et al. (1997) Novel disease resistance specificities result from sequence exchange between tandemly repeated genes[...]	GP00000181	Cf-4A Q7DLS4	Physiology	partial loss of two gene coding regions located in tandem; resulting in a chimeric gene	Solanum pimpinellifolium (species)	Solanum lycopersicum tomato - (species)	Cf-4/9	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
CHKov1	Pathogen resistance Xenobiotic resistance (insecticide)	Coding, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Magwire MM; Bayer F; Webster CL ; et al. (2011) Successive increases in the resistance of Drosophila to viral infection through a transposon inserti[...] 1 Additional References Aminetzach YT; Macpherson JM; Petrov DA (2005) Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila.	GP00000182	CHKov1 Q961V7	Physiology Physiology	Insertion of a Doc TE element resulting in novel; seemingly functional short protein	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	CHKov1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
CNL9 (=Sr35)	Pathogen resistance	Coding, Complex Change	Triticum monococcum (species)	Domesticated	Linkage Mapping	Saintenac C; Zhang W; Salcedo A ; et al. (2013) Identification of wheat gene Sr35 that confers resistance to Ug99 stem rust race group.	GP00000189	Sr35 S5ABD6	Physiology	Coding variation in the LRR domain - a spontaneous gene conversion between CNL4 and CNL9 is the most parsimonious explanation for the three linked mutations in CNL9	Triticum monococcum (species)	Triticum monococcum (species)	CNL9 (=Sr35)	Triticum monococcum (species)	Published - Accepted by Curator
ds1	Pathogen resistance	Unknown, Unknown	Sorghum bicolor sorghum - (species)	Domesticated	Linkage Mapping	Kawahigashi H; Kasuga S; Ando T ; et al. (2011) Positional cloning of ds1, the target leaf spot resistance gene against Bipolaris sorghicola in sorg[...]	GP00000238	ds1 K0IXC4	Physiology	unknown	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species)	ds1	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
GNBP1	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000408	GNBP1 Q9NHB0	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	GNBP1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
GNBP2	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000409	GNBP2 Q9VVR4	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	GNBP2	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
HM1 = HC toxin reductase (HCTR)	Pathogen resistance	Unknown, Unknown	Zea mays (species)	Domesticated	Candidate Gene	Multani DS; Meeley RB; Paterson AH ; et al. (1998) Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.	GP00000480	hm1 O49163	Physiology	Not identified	Zea mays (species)	Zea mays (species)	HM1 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
HM1 = HC toxin reductase (HCTR) [possible pseudo-replicate from other Maize entry]	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Linkage Mapping	Johal GS; Briggs SP (1992) Reductase activity encoded by the HM1 disease resistance gene in maize. 1 Additional References Multani DS; Meeley RB; Paterson AH (1998) Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.	GP00000481	hm1 O49163	Physiology	256-bp transposable element insertion in exon 4 N	Zea mays (species)	Zea mays (species) D	HM1 = HC toxin reductase (HCTR) [possible pseudo-replicate from other Maize entry]	Zea mays (species)	Published - Accepted by Curator
HM2 = HC toxin reductase (HCTR)	Pathogen resistance	Coding, Deletion N	Zea mays (species) D	Domesticated	Candidate Gene	Chintamanani S; Multani DS; Ruess H ; et al. (2008) Distinct mechanisms govern the dosage-dependent and developmentally regulated resistance conferred b[...]	GP00000482	hm2 B8QWA3	Physiology	deletion from exon 2 (nucleotide 420) to beyond the confines of the hm2 gene into an unknown genomic region. N	Zea mays (species)	Zea mays (species) D	HM2 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
HM2 = HC toxin reductase (HCTR)	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Candidate Gene	Chintamanani S; Multani DS; Ruess H ; et al. (2008) Distinct mechanisms govern the dosage-dependent and developmentally regulated resistance conferred b[...]	GP00000483	hm2 B8QWA3	Physiology	8-bp insertion in exon 1 that disrupt the reading frame and introduces a stop codon shortly after the beginning of the gene N	Zea mays (species)	Zea mays (species) D	HM2 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
I cluster	Pathogen resistance	Unknown, Unknown	Phaseolus vulgaris (species) D	Domesticated	Linkage Mapping	Vallejos CE; Astua-Monge G; Jones V ; et al. (2006) Genetic and molecular characterization of the I locus of Phaseolus vulgaris.	GP00000496	U5YMY7	Physiology	unknown; maps to a cluster of R-proteins	Phaseolus vulgaris (species)	Phaseolus vulgaris (species) D	I cluster	Phaseolus vulgaris (species)	Published - Accepted by Curator
IGK	Pathogen resistance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001382	IGKV1-5 P01602	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	IGK	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
Immune deficiency	Pathogen resistance	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sceurman BK; Clark AG (2004) Genetic basis of natural variation in D. melanogaster antibacterial immunity.	GP00000499	imd Q9NHG0	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Immune deficiency	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
L6	Pathogen resistance	Coding, Insertion N	Linum usitatissimum flax - (species)	Intraspecific	Linkage Mapping	Lawrence GJ; Finnegan EJ; Ayliffe MA ; et al. (1995) The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 an[...]	GP00000528	L6 Q40253	Physiology	Truncated protein due to insertion of a transposable element. Reversion to resistance among descendants of mutant X75 was associated with excision of the newly transposable element Ac. N	Linum usitatissimum flax - (species)	Linum usitatissimum flax - (species)	L6	Linum usitatissimum flax - (species)	Published - Accepted by Curator
Lr21	Pathogen resistance	Coding, Complex Change	Triticum aestivum bread wheat - (species)	Domesticated	Linkage Mapping	Huang L; Brooks S; Li W ; et al. (2009) Evolution of new disease specificity at a simple resistance locus in a crop-weed complex: reconstitu[...]	GP00000551	C5ID17	Physiology	Novel pathogen specificity resulting from chimerism of the parental alleles after intragenic recombination	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	Lr21	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
Lysine histidine transporter 1	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Linkage Mapping	Zhao Y; Lu X; Liu C ; et al. (2012) Identification and fine mapping of rhm1 locus for resistance to Southern corn leaf blight in maize.	GP00000555	LHT1 Q9FKS8	Physiology	354bp insertioin resulting in premature stop codon N	Zea mays (species)	Zea mays (species) D	Lysine histidine transporter 1	Zea mays (species)	Published - Accepted by Curator
M	Pathogen resistance	Coding, Deletion	Linum usitatissimum flax - (species) D	Intraspecific	Linkage Mapping	Anderson PA; Lawrence GJ; Morrish BC ; et al. (1997) Inactivation of the flax rust resistance gene M associated with loss of a repeated unit within the l[...]	GP00000559	P93244	Physiology	426bp deletion, probably by unequal recombination	Linum usitatissimum flax - (species)	Linum usitatissimum flax - (species) D	M	Linum usitatissimum flax - (species)	Published - Accepted by Curator
Mla (=Sr33/AetRGA1e)	Pathogen resistance	Coding, Unknown	Aegilops tauschii (species)	Domesticated	Linkage Mapping	Periyannan S; Moore J; Ayliffe M ; et al. (2013) The gene Sr33, an ortholog of barley Mla genes, encodes resistance to wheat stem rust race Ug99.	GP00000667	Mla1 Q7EXP5	Physiology	Unknown	Triticum aestivum bread wheat - (species)	Aegilops tauschii (species)	Mla (=Sr33/AetRGA1e)	Aegilops tauschii (species)	Published - Accepted by Curator
Mla1	Pathogen resistance	Coding, SNP	Hordeum vulgare (species)	Domesticated	Linkage Mapping	Mahadevappa M; Descenzo RA; Wise RP (1994) Recombination of alleles conferring specific resistance to powdery mildew at the Mla locus in barley[...] 3 Additional References Wei F; Gobelman-Werner K; Morroll SM (1999) The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppr[...] Halterman D; Zhou F; Wei F (2001) The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria g[...] Jordan T; Seeholzer S; Schwizer S (2011) The wheat Mla homologue TmMla1 exhibits an evolutionarily conserved function against powdery mildew [...]	GP00000668	Mla1 Q7EXP5	Physiology	Coding variation in the LRR domain - exact amino acid change unknown	Hordeum vulgare (species)	Hordeum vulgare (species)	Mla1	Hordeum vulgare (species)	Published - Accepted by Curator
Mla1	Pathogen resistance	Coding, Unknown	Triticum monococcum (species)	Domesticated	Candidate Gene	Halterman D; Zhou F; Wei F ; et al. (2001) The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria g[...] 1 Additional References Jordan T; Seeholzer S; Schwizer S (2011) The wheat Mla homologue TmMla1 exhibits an evolutionarily conserved function against powdery mildew [...]	GP00000669	Mla1 Q7EXP5	Physiology	Coding variation in the LRR domain	Triticum monococcum (species)	Triticum monococcum (species)	Mla1	Triticum monococcum (species)	Published - Accepted by Curator
Mla13	Pathogen resistance	Coding, SNP	Hordeum vulgare (species)	Domesticated	Linkage Mapping	Mahadevappa M; Descenzo RA; Wise RP (1994) Recombination of alleles conferring specific resistance to powdery mildew at the Mla locus in barley[...] 2 Additional References Wei F; Gobelman-Werner K; Morroll SM (1999) The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppr[...] Halterman D; Zhou F; Wei F (2001) The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria g[...]	GP00000670	Mla1 Q7EXP5	Physiology	Coding variation in the LRR domain - exact amino acid change unknown	Hordeum vulgare (species)	Hordeum vulgare (species)	Mla13	Hordeum vulgare (species)	Published - Accepted by Curator
Mla6	Pathogen resistance	Coding, SNP	Hordeum vulgare (species)	Domesticated	Linkage Mapping	Mahadevappa M; Descenzo RA; Wise RP (1994) Recombination of alleles conferring specific resistance to powdery mildew at the Mla locus in barley[...] 2 Additional References Wei F; Gobelman-Werner K; Morroll SM (1999) The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppr[...] Halterman D; Zhou F; Wei F (2001) The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria g[...]	GP00000671	Mla1 Q7EXP5	Physiology	Coding variation in the LRR domain - exact amino acid change(s) unknown	Hordeum vulgare (species)	Hordeum vulgare (species)	Mla6	Hordeum vulgare (species)	Published - Accepted by Curator
MLO	Pathogen resistance	Gene Amplification, Insertion	Hordeum vulgare (species) D	Domesticated	Linkage Mapping	Piffanelli P; Ramsay L; Waugh R ; et al. (2004) A barley cultivation-associated polymorphism conveys resistance to powdery mildew.	GP00000672	MLO P93766	Physiology	Tandem array duplication including promoter and partial CDS; resulting in loss-of-function by transcriptional interference	Hordeum vulgare (species)	Hordeum vulgare (species) D	MLO	Hordeum vulgare (species)	Published - Accepted by Curator
MLO1	Pathogen resistance	Coding, SNP N	Pisum sativum pea - (species)	Domesticated	Linkage Mapping	Pavan S; Schiavulli A; Appiano M ; et al. (2011) Pea powdery mildew er1 resistance is associated to loss-of-function mutations at a MLO homologous lo[...]	GP00000673	MLO P93766	Physiology	1bp substitution resulting in premature stop codon N	Pisum sativum pea - (species)	Pisum sativum pea - (species)	MLO1	Pisum sativum pea - (species)	Published - Accepted by Curator
MLO1	Pathogen resistance	Coding, Deletion N	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Bai Y; Pavan S; Zheng Z ; et al. (2008) Naturally occurring broad-spectrum powdery mildew resistance in a Central American tomato accession [...]	GP00000674	MLO P93766	Physiology	19bp deletion resulting in frameshift N	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species) D	MLO1	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
PGRP-LC	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000861	PGRP-LC Q9GNK5	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	PGRP-LC	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Pi-ta	Pathogen resistance	Coding, SNP	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Bryan GT; Wu KS; Farrall L ; et al. (2000) tA single amino acid difference distinguishes resistant and susceptible alleles of the rice blast re[...] 2 Additional References He Z; Zhai W; Wen H (2011) Two evolutionary histories in the genome of rice: the roles of domestication genes. Xu X; Liu X; Ge S (2011) Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically [...]	GP00000876	Pi-ta C9E6G5	Physiology	Ala918Ser	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi-ta	Oryza sativa rice - (species)	Published - Accepted by Curator
Pi2 (Nbs4-Pi2)	Pathogen resistance	Coding, SNP	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Zhou B; Qu S; Liu G ; et al. (2006) The eight amino-acid differences within three leucine-rich repeats between Pi2 and Piz-t resistance [...]	GP00000877	PI2 M1EC06	Physiology	eight amino acid changes - exact causing change(s) unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi2 (Nbs4-Pi2)	Oryza sativa rice - (species)	Published - Accepted by Curator
Pi36	Pathogen resistance	Coding, SNP	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Liu X; Lin F; Wang L ; et al. (2007) The in silico map-based cloning of Pi36, a rice coiled-coil nucleotide-binding site leucine-rich rep[...]	GP00000878	Pi36 D5J6W0	Physiology	Asp590Ser	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi36	Oryza sativa rice - (species)	Published - Accepted by Curator
Pi37	Pathogen resistance	Coding, SNP	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Lin F; Chen S; Que Z ; et al. (2007) The blast resistance gene Pi37 encodes a nucleotide binding site leucine-rich repeat protein and is [...]	GP00000879	Pi37 Q06AJ9	Physiology	V239A and I247M are the only amino acid substitutions found in all tested resistant strains- the effect of each individual amino acid change has not been tested	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi37	Oryza sativa rice - (species)	Published - Accepted by Curator
Pi5-1 + Pi5-2 cluster	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Lee SK; Song MY; Seo YS ; et al. (2009) Rice Pi5-mediated resistance to Magnaporthe oryzae requires the presence of two coiled-coil-nucleoti[...]	GP00000880	Pi5-1 C3SBK3	Physiology	In genetic transformation experiments of a susceptible rice cultivar neither the Pi5-1 nor the Pi5-2 gene was found to confer resistance to M. oryzae. In contrast transgenic rice plants expressing both of these genes (generated by crossing transgenic lines carrying each gene individually) conferred Pi5-mediated resistance to M. oryzae	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi5-1 + Pi5-2 cluster	Oryza sativa rice - (species)	Published - Accepted by Curator
Pi9 (= Nbs2-Pi9)	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Qu S; Liu G; Zhou B ; et al. (2006) The broad-spectrum blast resistance gene Pi9 encodes a nucleotide-binding site-leucine-rich repeat p[...]	GP00000881	Pi9 Q1WGB0	Physiology	Coding variation; necessary for resistance in completementation assay	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pi9 (= Nbs2-Pi9)	Oryza sativa rice - (species)	Published - Accepted by Curator
Pib	Pathogen resistance	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Wang ZX; Yano M; Yamanouchi U ; et al. (1999) The Pib gene for rice blast resistance belongs to the nucleotide binding and leucine-rich repeat cla[...]	GP00000882	Pi-b Q9SSY0	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pib	Oryza sativa rice - (species)	Published - Accepted by Curator
Pid3	Pathogen resistance	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Chen J; Shi Y; Liu W ; et al. (2011) A Pid3 allele from rice cultivar Gumei2 confers resistance to Magnaporthe oryzae.	GP00000883	Pid3 C0LMX9	Physiology	1bp deletion resulting in truncated protein N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Pid3	Oryza sativa rice - (species)	Published - Accepted by Curator
Pikm1-TS + Pikm2-TS cluster	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Ashikawa I; Hayashi N; Yamane H ; et al. (2008) Two adjacent nucleotide-binding site-leucine-rich repeat class genes are required to confer Pikm-spe[...] 1 Additional References Hua L; Wu J; Chen C (2012) The isolation of Pi1, an allele at the Pik locus which confers broad spectrum resistance to rice bla[...]	GP00000884	PIKM1-TS B5UBC1	Physiology	Coding variation in both genes; with alleles of both genes necessary for resistance in completementation assays	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pikm1-TS + Pikm2-TS cluster	Oryza sativa rice - (species)	Published - Accepted by Curator
Piz-t	Pathogen resistance	Coding, SNP	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Zhou B; Qu S; Liu G ; et al. (2006) The eight amino-acid differences within three leucine-rich repeats between Pi2 and Piz-t resistance [...]	GP00000895	Piz-t Q0H213	Physiology	Coding variation in the LRR domain	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Piz-t	Oryza sativa rice - (species)	Published - Accepted by Curator
Pl6	Pathogen resistance	Coding, Unknown	Helianthus annuus common sunflower - (species) D	Domesticated	Linkage Mapping	Franchel J; Bouzidi MF; Bronner G ; et al. (2013) Positional cloning of a candidate gene for resistance to the sunflower downy mildew, Plasmopara hals[...]	GP00000896	F8R6K4	Physiology	unknown ; cluster of several R-protein coding genes; of which only one is expressed	Helianthus annuus common sunflower - (species)	Helianthus annuus common sunflower - (species) D	Pl6	Helianthus annuus common sunflower - (species)	Published - Accepted by Curator
Pm3	Pathogen resistance	Coding, SNP	Triticum aestivum bread wheat - (species)	Intraspecific	Linkage Mapping	Yahiaoui N; Kaur N; Keller B (2009) Independent evolution of functional Pm3 resistance genes in wild tetraploid wheat and domesticated b[...] 1 Additional References Yahiaoui N; Brunner S; Keller B (2006) Rapid generation of new powdery mildew resistance genes after wheat domestication.	GP00000899	PM3 C1K3M2	Physiology	Various substitution haplotypes - exact causing amino acid change(s) unknown - in hexaploid bread wheat one amino acid change in a solvent‐exposed residue of LRR27 (E1334 to V1334) was sufficient to convert the susceptible Pm3CS into a functional resistance allele (Yahiaoui et al., 2006).	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	Pm3	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
PRKCD	Pathogen resistance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001381	PRKCD Q05655	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	PRKCD	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
Pto	Pathogen resistance	Unknown, Unknown	Solanum lycopersicum tomato - (species)	Domesticated	Linkage Mapping	Martin GB; Brommonschenkel SH; Chunwongse J ; et al. (1993) Map-based cloning of a protein kinase gene conferring disease resistance in tomato.	GP00000937	pto P93215	Physiology	Not identified	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species)	Pto	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
RAC1	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Borhan MH; Holub EB; Beynon JL ; et al. (2004) The arabidopsis TIR-NB-LRR gene RAC1 confers resistance to Albugo candida (white rust) and is depend[...]	GP00000949	ARAC3 Q38912	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RAC1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RCR3	Pathogen resistance	Coding, SNP	Solanum peruvianum (species)	Intraspecific	Candidate Gene	Hörger AC; Ilyas M; Stephan W ; et al. (2012) Balancing selection at the tomato RCR3 Guardee gene family maintains variation in strength of pathog[...]	GP00000963	Rcr3 Q8S333	Physiology	Candidate amino acid changes are I206K and/or Q222E and/or S330A	Solanum peruvianum (species)	Solanum peruvianum (species)	RCR3	Solanum peruvianum (species)	Published - Accepted by Curator
RGC2/Dm3	Pathogen resistance	Coding, Unknown	Lactuca serriola (species)	Domesticated	Linkage Mapping	Kuang H; Ochoa OE; Nevo E ; et al. (2006) The disease resistance gene Dm3 is infrequent in natural populations of Lactuca serriola due to dele[...]	GP00000984	RGC2 Q6Y136	Physiology	Various haplotypes detected using PCR - absence of amplification could be due to deletion or to gene conversion	Lactuca serriola (species)	Lactuca serriola (species)	RGC2/Dm3	Lactuca serriola (species)	Published - Accepted by Curator
RLM1	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Bohman S ; et al. (2006) Transgressive segregation reveals two Arabidopsis TIR-NB-LRR resistance genes effective against Lept[...]	GP00000991	RLM1A F4I594	Physiology	Digenic; deletion of gene1 and premature stop codons in gene2 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RLM2 cluster	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Bohman S ; et al. (2006) Transgressive segregation reveals two Arabidopsis TIR-NB-LRR resistance genes effective against Lept[...]	GP00000992	RLM1B Q9CAK1	Physiology	the locus contains two paralogues; one of which is deleted and the other pseudogenized in Ler-0 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM2 cluster	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RLM3	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Dewaele E ; et al. (2008) RLM3, a TIR domain encoding gene involved in broad-range immunity of Arabidopsis to necrotrophic fun[...]	GP00000993	RLM3 Q9FT77	Physiology	gene deletion N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM3	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Rp1-D	Pathogen resistance	Gene Amplification, Complex Change	Zea mays (species)	Domesticated	Candidate Gene	Collins N; Drake J; Ayliffe M ; et al. (1999) Molecular characterization of the maize Rp1-D rust resistance haplotype and its mutants. 2 Additional References Sun Q; Collins NC; Ayliffe M (2001) Recombination between paralogues at the Rp1 rust resistance locus in maize. Luo S; Peng J; Li K (2011) Contrasting evolutionary patterns of the Rp1 resistance gene family in different species of Poaceae.	GP00000998	Rp1-D Q9SWU0	Physiology	Unequal crossing over between paralogues resulting in chimeric gene	Zea mays (species)	Zea mays (species)	Rp1-D	Zea mays (species)	Published - Accepted by Curator
Rp3 cluster	Pathogen resistance	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Webb CA; Richter TE; Collins NC ; et al. (2002) Genetic and molecular characterization of the maize rp3 rust resistance locus.	GP00000999	rp3-1 Q6PW75	Physiology	unknown	Zea mays (species)	Zea mays (species)	Rp3 cluster	Zea mays (species)	Published - Accepted by Curator
RPM1	Pathogen resistance	Gene Loss, Indel N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Grant MR; McDowell JM; Sharpe AG ; et al. (1998) Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis. 2 Additional References Atwell S; Huang YS; Vilhjálmsson BJ (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Stahl EA; Dwyer G; Mauricio R (1999) Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis.	GP00001000	RPM1 Q39214	Physiology	3.7kb indel with a null-state in the sensitive strains N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPM1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPM1	Pathogen resistance	Gene Loss, Complex Change N	Brassica napus rape - (species)	Intraspecific	Linkage Mapping	Grant MR; McDowell JM; Sharpe AG ; et al. (1998) Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis.	GP00001001	RPM1 Q39214	Physiology	deletion N	Brassica napus rape - (species)	Brassica napus rape - (species)	RPM1	Brassica napus rape - (species)	Published - Accepted by Curator
RPP1-WsA	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001002	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsA	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP1-WsB	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001003	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsB	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP1-WsC	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001004	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsC	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP13	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Interspecific	Linkage Mapping	Rose LE; Bittner-Eddy PD; Langley CH ; et al. (2004) The maintenance of extreme amino acid diversity at the disease resistance gene, RPP13, in Arabidopsi[...]	GP00001005	RPP13 Q9M667	Physiology	Various haplotypes	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP13	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP2A-RPP2B	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Sinapidou E; Williams K; Nott L ; et al. (2004) Two TIR:NB:LRR genes are required to specify resistance to Peronospora parasitica isolate Cala2 in A[...]	GP00001006	RPP2A P51407	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP2A-RPP2B	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP4	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	van der Biezen EA; Freddie CT; Kahn K ; et al. (2002) Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mild[...]	GP00001007	RPP4 F4JNA9	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP5	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	van der Biezen EA; Freddie CT; Kahn K ; et al. (2002) Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mild[...] 1 Additional References Nemri A; Atwell S; Tarone AM (2010) Genome-wide survey of Arabidopsis natural variation in downy mildew resistance using combined associ[...]	GP00001008	RPP5 F4JNB7	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP5	Pathogen resistance	Gene Amplification, Complex Change	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Parker JE; Coleman MJ; Szabò V ; et al. (1997) The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the toll and interleukin-1 re[...] 1 Additional References Nemri A; Atwell S; Tarone AM (2010) Genome-wide survey of Arabidopsis natural variation in downy mildew resistance using combined associ[...]	GP00001009	RPP5 F4JNB7	Physiology	Partial duplication sufficient to increase resistance	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP8	Pathogen resistance	Coding, Complex Change	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	McDowell JM; Dhandaydham M; Long TA ; et al. (1998) Intragenic recombination and diversifying selection contribute to the evolution of downy mildew resi[...] 1 Additional References Nemri A; Atwell S; Tarone AM (2010) Genome-wide survey of Arabidopsis natural variation in downy mildew resistance using combined associ[...]	GP00001010	RPP8 Q8W4J9	Physiology	Chimeric fusion of two paralogues followed by coding divergence	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP8	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS2	Pathogen resistance	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Mindrinos M; Katagiri F; Yu GL ; et al. (1994) The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site [...]	GP00001011	RPS2 Q42484	Physiology	10bp insertion close to the 5' end causing a frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RPS2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS2	Pathogen resistance	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Caicedo AL; Schaal BA; Kunkel BN (1999) Diversity and molecular evolution of the RPS2 resistance gene in Arabidopsis thaliana.	GP00001012	RPS2 Q42484	Physiology	W235* due to G704A N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPS2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS4	Pathogen resistance	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Narusaka M; Shirasu K; Noutoshi Y ; et al. (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens. 1 Additional References Narusaka M; Shirasu K; Noutoshi Y (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens.	GP00001013	RPS4 Q9XGM3	Physiology	5bp deletion resulting in frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RPS4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS5	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Henk AD; Warren RF; Innes RW (1999) A new Ac-like transposon of Arabidopsis is associated with a deletion of the RPS5 disease resistance[...] 1 Additional References Atwell S; Huang YS; Vilhjálmsson BJ (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines.	GP00001014	RPS5 O64973	Physiology	Deletion N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPS5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RRS1	Pathogen resistance	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Narusaka M; Shirasu K; Noutoshi Y ; et al. (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens. 1 Additional References Birker D; Heidrich K; Takahara H (2009) A locus conferring resistance to Colletotrichum higginsianum is shared by four geographically distin[...]	GP00001015	RRS1 P0DKH5	Physiology	Premature stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RRS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
SIGLEC13	Pathogen resistance	Gene Loss, Complex Change N	Homo sapiens human - (species)	Interspecific	Candidate Gene	Wang X; Mitra N; Secundino I ; et al. (2012) Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.	GP00001052	SIGLEC13 Q64JA4	Physiology	Gene deletion by Alu-mediated recombination N	Primates (order)	Homo sapiens human - (species)	SIGLEC13	Homo sapiens human - (species)	Published - Accepted by Curator
SIGLEC17P (pseudogene)	Pathogen resistance	Coding, Deletion N	Homo sapiens human - (species) D	Interspecific	Candidate Gene	Wang X; Mitra N; Secundino I ; et al. (2012) Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.	GP00001053	SIGLEC13 Q64JA4	Physiology	1bp deletion resulting in frame-shift (pseudogenization) N	Primates (order)	Homo sapiens human - (species) D	SIGLEC17P (pseudogene)	Homo sapiens human - (species)	Published - Accepted by Curator
SR-CII	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00001071	Sr-CII Q5ELW9	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	SR-CII	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Tehao	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00001115	Tehao Q9VJX9	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Tehao	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
WRR4	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Borhan MH; Gunn N; Cooper A ; et al. (2008) WRR4 encodes a TIR-NB-LRR protein that confers broad-spectrum white rust resistance in Arabidopsis t[...]	GP00001215	ADR2 Q9C7X0	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	WRR4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Xa1	Pathogen resistance	Unknown, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Yoshimura S; Yamanouchi U; Katayose Y ; et al. (1998) Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation.	GP00001216	XA1 A0A0H5AGW3	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa1	Oryza sativa rice - (species)	Published - Accepted by Curator
Xa21	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Song WY; Wang GL; Chen LL ; et al. (1995) A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21.	GP00001217	Xa21 A0PIA3	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa21	Oryza sativa rice - (species)	Published - Accepted by Curator
Xa26	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Sun X; Cao Y; Yang Z ; et al. (2004) Xa26, a gene conferring resistance to Xanthomonas oryzae pv. oryzae in rice, encodes an LRR receptor[...]	GP00001218	Xa26 Q00KZ8	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa26	Oryza sativa rice - (species)	Published - Accepted by Curator