Gephebase

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This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 130 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
AEP2	Hybrid Incompatibility (F2 sterility)	Coding, SNP	Saccharomyces bayanus (species)	Domesticated	Linkage Mapping	Lee HY; Chou JY; Cheong L ; et al. (2008) Incompatibility of nuclear and mitochondrial genomes causes hybrid sterility between two yeast speci[...]	GP00000051	AEP2 P22136	Physiology	The region between aa 348 and aa 496 plays a critical role. When this region was further dissected in the constructs H-AEP2-bcb and H-AEP2-m3; both failed to restore respiration in the Chromosome 13 line. This result suggests that multiple critical mutations have occurred during the functional diversification of Sc-AEP2 and Sb-AEP2. Exact causing mutation(s) not determined	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces bayanus (species)	AEP2	Saccharomyces bayanus (species)	Published - Accepted by Curator
AIM22	F2 lethality	Coding, SNP	Saccharomyces bayanus (species)	Interspecific	Linkage Mapping	Chou JY; Hung YS; Lin KH ; et al. (2010) Multiple molecular mechanisms cause reproductive isolation between three yeast species.	GP00000073	AIM22 P47051	Physiology	Several candidate non-synonymous changes - exact causing mutation(s) unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces bayanus (species)	AIM22	Saccharomyces bayanus (species)	Published - Accepted by Curator
Allantoin permease DAL4	Nitrogen use (growth rate on allantoin)	Coding, Indel N	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001503	DAL4 Q04895	Physiology	c.1201delA a single nucleotide frameshifting insertion (deletion?) N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Allantoin permease DAL4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Allantoinase DAL1	Nitrogen use (growth rate on allantoin)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001502	DAL1 P32375	Physiology	c.415C>T p.P139S predicted to be strongly detrimental	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Allantoinase DAL1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
AMN1	Cell separation	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Yvert G; Brem RB; Whittle J ; et al. (2003) Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors.	GP00000082	AMN1 P38285	Physiology	D368V	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	AMN1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
APJ1	Xenobiotic resistance (alcohol, ethanol)	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Swinnen S; Schaerlaekens K; Pais T ; et al. (2012) Identification of novel causative genes determining the complex trait of high ethanol tolerance in y[...]	GP00000097	APJ1 P53940	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	APJ1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	2 Mutations: Coding SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001872	AQP1 P29972	Physiology	2 mutations	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001873	AQP1 P29972	Physiology	aquaporin yeast 1 gene on chromosome 12 - A881 deletion renders AQY1 inactive - size of the deletion not indicated in the paper - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001874	AQP1 P29972	Physiology	aquaporin yeast 1 gene on chromosome 12 - 955-bp deletion that removes the first 106 bp of AQY1 and its upstream region - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Carbrey JM; Bonhivers M; Boeke JD (2001) Aquaporins in Saccharomyces: Characterization of a second functional water channel protein.	GP00001875	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - 11-bp deletion that creates a stop codon in the middle of the AQY2 gene - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Laizé V; Tacnet F; Ripoche P (2000) Polymorphism of Saccharomyces cerevisiae aquaporins.	GP00001876	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - deletion of nucleotide G at position 25 (G25) which creates a frameshift the AQY2 gene - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...]	GP00001877	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - G528 deletion which creates a frameshift the AQY2 gene - tested in assays - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ASP1	Acetic acid production	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Marullo P; Aigle M; Bely M ; et al. (2007) Single QTL mapping and nucleotide-level resolution of a physiologic trait in wine Saccharomyces cere[...]	GP00000104	APS1 P35181	Physiology	Asp142His	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	ASP1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001488	BMH1 P29311	Physiology	C>G p.Y216* heterozygous. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001489	BMH1 P29311	Physiology	G>T p.E214*. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001490	BMH1 P29311	Physiology	A>T p.K217* (2 times independently). Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001491	BMH1 P29311	Physiology	G>A p.D101N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001492	BMH1 P29311	Physiology	T>G p.L230* heterozygous. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001493	BMH1 P29311	Physiology	C>A p.N178K located inside the groove where Bmh1p is expected to interact with other proteins as predicted by docking with arbitrary peptides and with two known Bmh1 protein partners (Serine/threonine-protein phosphatase PP1-2 and Heat shock protein Ssb1)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001494	BMH1 P29311	Physiology	G>T p.E214*. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001495	BMH1 P29311	Physiology	G>T p.G174V homozygous functionally disruptive located inside the groove where Bmh1p is expected to interact with other proteins as predicted by docking with arbitrary peptides and with two known Bmh1 protein partners (Serine/threonine-protein phosphatase	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001496	BMH1 P29311	Physiology	G>A p.G174D located inside the groove where Bmh1p is expected to interact with other proteins as predicted by docking with arbitrary peptides and with two known Bmh1 protein partners (Serine/threonine-protein phosphatase PP1-2 and Heat shock protein Ssb1)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001497	BMH1 P29311	Physiology	A>G p.N178S homozygous functionally disruptive located inside the groove where Bmh1p is expected to interact with other proteins as predicted by docking with arbitrary peptides and with two known Bmh1 protein partners (Serine/threonine-protein phosphatase	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001498	BMH1 P29311	Physiology	G>A p.G55D located inside the groove where Bmh1p is expected to interact with other proteins as predicted by docking with arbitrary peptides and with two known Bmh1 protein partners (Serine/threonine-protein phosphatase PP1-2 and Heat shock protein Ssb1)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BUL2	Telomere length Aging	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Kwan EX; Foss E; Kruglyak L ; et al. (2011) Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and tel[...]	GP00000166	BUL2 Q03758	Physiology Physiology	Leu883Phe	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	BUL2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
CIS1	Xenobiotic resistance (citrinin)	Cis-regulatory, Unknown	Saccharomyces paradoxus (species) D	Domesticated	Association Mapping	Naranjo S; Smith JD; Artieri CG ; et al. (2015) Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation.	GP00001313	ATG31 Q12421	Physiology	mutations within 1kb in promotor region	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces paradoxus (species) D	CIS1	Saccharomyces paradoxus (species)	Published - Accepted by Curator
COX18	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001708	COX18 P53239	Physiology	Leu59His (T>A at position 617107 according to Table 1) - CTY to CAY position 617107	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	COX18	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
CYC8	Salt tolerance (experimental evolution)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 1 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...]	GP00000195	CYC8 P14922	Physiology	1bp substitution resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	CYC8	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
cytochrome b	Xenobiotic resistance (fungicide; QoI; quinone outside inhibiting)	Coding, SNP	Schizosaccharomyces pombe fission yeast - (species) D	Interspecific	Candidate Gene	Kraiczy P; Haase U; Gencic S ; et al. (1996) The molecular basis for the natural resistance of the cytochrome bc1 complex from strobilurin-produc[...]	GP00002046	UQCRFS1 P47985	Physiology	N261D	Saccharomyces cerevisiae baker's yeast - (species)	Schizosaccharomyces pombe fission yeast - (species) D	cytochrome b	Schizosaccharomyces pombe fission yeast - (species)	Published - Accepted by Curator
ENA1-2-5 cluster	Salt tolerance (experimental evolution)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 1 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...]	GP00000265	ENA1 P13587	Physiology	uncharacterized expansion	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	ENA1-2-5 cluster	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ENA1-2-5 cluster	Salt tolerance (experimental evolution)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000266	ENA1 P13587	Physiology	uncharacterized expansion	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ENA1-2-5 cluster	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
END3	Temperature tolerance Virulence	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Steinmetz LM; Sinha H; Richards DR ; et al. (2002) Dissecting the architecture of a quantitative trait locus in yeast. 1 Additional References Sinha H; Nicholson BP; Steinmetz LM (2006) Complex genetic interactions in a quantitative trait locus.	GP00000267	END3 P39013	Physiology Physiology	S258N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	END3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
END3	Temperature tolerance Virulence	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Steinmetz LM; Sinha H; Richards DR ; et al. (2002) Dissecting the architecture of a quantitative trait locus in yeast. 1 Additional References Sinha H; Nicholson BP; Steinmetz LM (2006) Complex genetic interactions in a quantitative trait locus.	GP00000268	END3 P39013	Physiology Physiology	D268N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	END3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000286	ERG3 P32353	Physiology	Arg63Stop A187T in line 21 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001744	ERG3 P32353	Physiology	Ser76Stop C227A in line 22 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001745	ERG3 P32353	Physiology	Ser95Stop C284A in line 23 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001746	ERG3 P32353	Physiology	Trp205Stop G615A in line 24 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001747	ERG3 P32353	Physiology	Trp205Stop G615A in line 25 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001748	ERG3 P32353	Physiology	Trp205Stop G615A in line 26 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001749	ERG3 P32353	Physiology	Trp205Stop G615A in line 27 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001750	ERG3 P32353	Physiology	29-bp duplication in line 28 at nucleotide position 641 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001751	ERG3 P32353	Physiology	Trp219Stop G656A in line 29 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001752	ERG3 P32353	Physiology	Gly235Ser G703A in line 30 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001753	ERG3 P32353	Physiology	Tyr299Stop C897A in line 31 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001754	ERG3 P32353	Physiology	Gly300Arg G898C in line 32 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001755	ERG3 P32353	Physiology	Asp307Ala A920C in line 33 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001756	ERG3 P32353	Physiology	1-bp deletion in line 34 A980- N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001757	ERG3 P32353	Physiology	60-bp deletion at position 253 in line 35 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG5	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000287	ERG5 P54781	Physiology	60bp deletion N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG6	Xenobiotic resistance (drug)	Coding, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000288	erg6 O14321	Physiology	7 unique mutations in ERG6 within a total 19 lines ; 4 of these mutations evolved multiple times	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	ERG6	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG7	Xenobiotic resistance (drug)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000289	ERG7 P38604	Physiology	Phe699Leu	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG7	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
FLO1	Cell separation	Other, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Candidate Gene	Smukalla S; Caldara M; Pochet N ; et al. (2008) FLO1 is a variable green beard gene that drives biofilm-like cooperation in budding yeast. 1 Additional References Verstrepen KJ; Jansen A; Lewitter F (2005) Intragenic tandem repeats generate functional variability.	GP00000342	FLO1 P32768	Physiology	both coding and non-coding divergence ; polyQ variation	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	FLO1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
FRM2	Xenobiotic resistance (citrinin)	Cis-regulatory, Unknown	Saccharomyces paradoxus (species) D	Domesticated	Association Mapping	Naranjo S; Smith JD; Artieri CG ; et al. (2015) Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation.	GP00001311	FRM2 P37261	Physiology	mutations within 1kb in promotor region	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces paradoxus (species) D	FRM2	Saccharomyces paradoxus (species)	Published - Accepted by Curator
GAL1	Carbohydrate metabolism (galactose)	Cis-regulatory, Complex Change	Saccharomyces cerevisiae baker's yeast - (species)	Intergeneric or Higher	Candidate Gene	Hittinger CT; Carroll SB (2007) Gene duplication and the adaptive evolution of a classic genetic switch.	GP00000385	GAL1 P09608	Physiology	Helical phasing of GAL4 elements in promoter region following duplication	Kluyveromyces lactis (species)	Saccharomyces cerevisiae baker's yeast - (species)	GAL1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL1	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001425	GAL1 P04385	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL10	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001428	GAL10 P04397	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL10	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL3	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001426	GAL3 P13045	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL4	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001427	GAL4 P04386	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GPA1	Pheromone response Cell elongation	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Yvert G; Brem RB; Whittle J ; et al. (2003) Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. 1 Additional References Nogami S; Ohya Y; Yvert G (2007) Genetic complexity and quantitative trait loci mapping of yeast morphological traits.	GP00000410	GPA1 P08539	Physiology Physiology	Ser469Ile	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	GPA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GPX2	Xenobiotic resistance (citrinin)	Cis-regulatory, Unknown	Saccharomyces paradoxus (species) D	Interspecific	Association Mapping	Naranjo S; Smith JD; Artieri CG ; et al. (2015) Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation.	GP00001310	GPX2 P38143	Physiology	mutations within 1kb in promotor region	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces paradoxus (species) D	GPX2	Saccharomyces paradoxus (species)	Published - Accepted by Curator
HXT6/7	Low-glucose adaptation (experimental evolution)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Brown CJ; Todd KM; Rosenzweig RF (1998) Multiple duplications of yeast hexose transport genes in response to selection in a glucose-limited [...] 4 Additional References Dunham MJ; Badrane H; Ferea T (2002) Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae. Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...] Gresham D; Desai MM; Tucker CM (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00000494	HXT6 P39003	Physiology	expansion by inequal recombination between HXT6 and HXT7 (99% nucleotide similarity) ; replicated in two independent studies and in multiple lines	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	HXT6/7	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
IME1	Sporulation efficiency	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Gerke J; Lorenz K; Cohen B (2009) Genetic interactions between transcription factors cause natural variation in yeast.	GP00000498	IME1 P21190	Physiology	L325M and/or 1bp synonymous substitution	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	IME1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
IRA1	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001709	IRA1 P18963	Physiology	Arg1583Lys (G>A at position 521875 according to Table 1) - AGR to AAR position 521875	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	IRA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
IRA2	Growth rate (environment-dependent)	Coding, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Smith EN; Kruglyak L (2008) Gene-environment interaction in yeast gene expression.	GP00000505	IRA2 P19158	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	IRA2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
LEU2	Xenobiotic resistance	Gene Loss, Complex Change N	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Perlstein EO; Ruderfer DM; Roberts DC ; et al. (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast.	GP00000542	LEU2 P04173	Physiology	Deletion N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	LEU2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MAM3	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001303	PMA1 P05030	Physiology	C>G (Gly > Arg) @ position 250	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MAM3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MAM3	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001304	PMA1 P05030	Physiology	C>T (Val > Ile) @ position 1120	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MAM3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MAM3	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001305	PMA1 P05030	Physiology	C>T (Ser > Asn) @ position 806	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MAM3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MDS3	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 1 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...]	GP00000641	MDS3 P53094	Physiology	Phe - Val substitution	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MDS3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MEP2	Salt tolerance (experimental evolution; low ammonium)	Other, Complex Change	Saccharomyces uvarum (species)	Experimental Evolution	Association Mapping	Dunn B; Paulish T; Stanbery A ; et al. (2013) Recurrent rearrangement during adaptive evolution in an interspecific yeast hybrid suggests a model [...]	GP00000651	MEP2 P41948	Physiology	Chimeric gene in diploid hybrids formed by recombination between the parental alleles	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces uvarum (species)	MEP2	Saccharomyces uvarum (species)	Published - Accepted by Curator
metallothionein CUP1	Metal tolerance (copper)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001289	CUP1-1 P0CX80	Physiology	Gene duplication	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	metallothionein CUP1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MKT1	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 1 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...]	GP00000662	MKT1 P40850	Physiology	D30G (reversion; functionally verified); evolved independently in 3 lines	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MKT1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MKT1	Temperature tolerance Virulence Sporulation efficiency Sporulation efficiency Xenobiotic resistance (alcohol; ethanol) Xenobiotic resistance (genotoxic DNA-damage agent)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Steinmetz LM; Sinha H; Richards DR ; et al. (2002) Dissecting the architecture of a quantitative trait locus in yeast. 5 Additional References Sinha H; Nicholson BP; Steinmetz LM (2006) Complex genetic interactions in a quantitative trait locus. Demogines A; Smith E; Kruglyak L (2008) Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. Swinnen S; Schaerlaekens K; Pais T (2012) Identification of novel causative genes determining the complex trait of high ethanol tolerance in y[...] Ehrenreich IM; Torabi N; Jia Y (2010) Dissection of genetically complex traits with extremely large pools of yeast segregants. Deutschbauer AM; Davis RW (2005) Quantitative trait loci mapped to single-nucleotide resolution in yeast.	GP00000666	MKT1 P40850	Physiology Physiology Physiology Physiology Physiology Physiology	G30D (functionally verified); or haplotype including G30D (functionally verified)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	MKT1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MNN4	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001711	MNN4 P36044	Physiology	Lys924Glu (A>G at position 64698 according to Table 1) - AAR to GAR position 64698	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MNN4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MRS1	F2 lethality	3 Mutations: Coding SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Linkage Mapping	Chou JY; Hung YS; Lin KH ; et al. (2010) Multiple molecular mechanisms cause reproductive isolation between three yeast species.	GP00000678	MRS1 P07266	Physiology	3 mutations	Saccharomyces paradoxus (species) Saccharomyces bayanus (species) Saccharomyces kudriavzevii (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MRS1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MTH1	Low-glucose adaptation (experimental evolution)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00000679	CUP1-1 P0CX80	Physiology	1bp substitution resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MTH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MTH1	Low-glucose adaptation (experimental evolution)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00000680	CUP1-1 P0CX80	Physiology	Ty retrotranposition resulting in a coding frameshift N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MTH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MUK1	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001713	MUK1 Q02866	Physiology	Ser441STP(C>A at position 422266 according to Table 1) - TCR to TAR position 422266	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MUK1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PHO5	Low-phosphate adaptation (experimental evolution)	Gene Amplification, Deletion	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00000863	PHO5 P00635	Physiology	Deletion. Out of 8 lines; 2 distinct lines evolved structural variation at PHO5. (Interestingly; one was a deletion and another one was a gene amplification)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	PHO5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PHO5	Low-phosphate adaptation (experimental evolution)	Gene Amplification, Insertion	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00000864	PHO5 P00635	Physiology	Gene duplication. Out of 8 lines; 2 distinct lines evolved structural variation at PHO5. (Interestingly; one was a deletion and another one was a gene amplification)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	PHO5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PHO84	Xenobiotic resistance	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Perlstein EO; Ruderfer DM; Roberts DC ; et al. (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast.	GP00000865	PHO84 P25297	Physiology	L259P	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	PHO84	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Plasma membrane ATPase 1	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001300	PMA1 P05030	Physiology	A>T (Phe > Ile) @ position 1831	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Plasma membrane ATPase 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Plasma membrane ATPase 1	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001301	PMA1 P05030	Physiology	T>G (Thr > Pro) @ position 2197	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Plasma membrane ATPase 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Plasma membrane ATPase 1	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001302	PMA1 P05030	Physiology	G>T (Ala > Asp) @ position 2204	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Plasma membrane ATPase 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 2 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...] Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000900	PMA1 P05030	Physiology	Leu363Trp	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 2 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...] Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000901	PMA1 P05030	Physiology	Ser234Cys	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000902	PMA1 P05030	Physiology	Val127Phe	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000903	PMA1 P05030	Physiology	Val157Phe	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000904	PMA1 P05030	Physiology	Gly294Val	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000905	PMA1 P05030	Physiology	Gly337Ser	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000906	PMA1 P05030	Physiology	Met530Ile	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000907	PMA1 P05030	Physiology	Pro535Thr	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000908	PMA1 P05030	Physiology	Iso564Thr	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000909	PMA1 P05030	Physiology	Ala732Val	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMA1	Salt tolerance (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000910	PMA1 P05030	Physiology	Trp750Cys	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMA1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
PMR1	Metal tolerance (manganese)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Sadhu MJ; Bloom JS; Day L ; et al. (2016) CRISPR-directed mitotic recombination enables genetic mapping without crosses.	GP00000914	PMR1 P13586	Physiology	Leu548Phe	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	PMR1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Proline specific permease PUT4	Nitrogen use (growth rate on proline)	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001501	PUT4 P15380	Physiology	several synonymous and promoter mutations	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Proline specific permease PUT4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RAD5	Xenobiotic resistance	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Demogines A; Smith E; Kruglyak L ; et al. (2008) Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. 1 Additional References Ehrenreich IM; Torabi N; Jia Y (2010) Dissection of genetically complex traits with extremely large pools of yeast segregants.	GP00000950	RAD5 P32849	Physiology	I791S	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	RAD5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RAS1	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000952	RAS2 P01120	Physiology	Glu>Ala (A>C mutation)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RAS1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RAS2	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000954	RAS2 P01120	Physiology	Gly>Ser (C>T mutation)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RAS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RAS2	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kohn LM; Anderson JB (2014) The underlying structure of adaptation under strong selection in 12 experimental yeast populations.	GP00000955	RAS2 P01120	Physiology	Glu>Gln (C>G mutation)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RAS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RAS2	Sporulation efficiency	Cis-regulatory, Insertion	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Ben-Ari G; Zenvirth D; Sherman A ; et al. (2006) Four linked genes participate in controlling sporulation efficiency in budding yeast.	GP00000956	RAS2 P01120	Physiology	1bp insertion in promoter	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RAS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Rds2	Oxidative stress resistance	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Diezmann S; Dietrich FS (2011) Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major qu[...]	GP00000964	RDS2 P19541	Physiology	H251D	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	Rds2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RHO2	Temperature tolerance / virulence	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Steinmetz LM; Sinha H; Richards DR ; et al. (2002) Dissecting the architecture of a quantitative trait locus in yeast. 1 Additional References Sinha H; Nicholson BP; Steinmetz LM (2006) Complex genetic interactions in a quantitative trait locus.	GP00000986	RHO2 P06781	Physiology	3'UTR polymorphism	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	RHO2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RIM15	Low-glucose adaptation (experimental evolution)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00000989	RIM15 P43565	Physiology	1bp deletion resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RIM15	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RME1	Sporulation efficiency	Cis-regulatory, Deletion	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Deutschbauer AM; Davis RW (2005) Quantitative trait loci mapped to single-nucleotide resolution in yeast.	GP00000994	RME1 P32338	Physiology	single nucleotide deletion in promoter region	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RME1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RME1 [possible pseudo-replicate of laboratory strain entry]	Sporulation efficiency	Cis-regulatory, Deletion	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Gerke J; Lorenz K; Cohen B (2009) Genetic interactions between transcription factors cause natural variation in yeast.	GP00000995	RME1 P32338	Physiology	single nucleotide deletion in promoter region	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RME1 [possible pseudo-replicate of laboratory strain entry]	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RSF1	Sporulation efficiency	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Gerke J; Lorenz K; Cohen B (2009) Genetic interactions between transcription factors cause natural variation in yeast.	GP00001016	HFR1 Q9FE22	Physiology	D181G	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	RSF1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RTA1	Xenobiotic resistance (citrinin)	Cis-regulatory, Unknown	Saccharomyces paradoxus (species) D	Domesticated	Association Mapping	Naranjo S; Smith JD; Artieri CG ; et al. (2015) Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation.	GP00001312	RTA1 P53047	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces paradoxus (species) D	RTA1	Saccharomyces paradoxus (species)	Published - Accepted by Curator
Serine/threonine protein kinase RIM15	Nitrogen use (growth efficiency)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001500	RIM15 P43565	Physiology	2 bp insertion 459_460insCA shifting the reading frame to cause an early stop codon (null allele) N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Serine/threonine protein kinase RIM15	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SIR2	Longevity	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00001054	SIR2 P06700	Physiology	1 to 5 amino-acid substitutions	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SIR2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SLY41	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001712	SLY41 P22215	Physiology	Trp253Leu (G>T at position 893332 according to Table 1)	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	SLY41	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SUL1	Low-sulfate adaptation (experimental evolution)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...] 1 Additional References Araya CL; Payen C; Dunham MJ (2010) Whole-genome sequencing of a laboratory-evolved yeast strain.	GP00001083	SUL1 P38359	Physiology	out of 16 lines; 15 distinct SUL1 amplification alleles evolved. Copy number ranged from 2 to 16 ; Amplicon size ranged from 2.5kb to 40kb	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SUL1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SWS2	Xenobiotic resistance (alcohol, ethanol)	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Swinnen S; Schaerlaekens K; Pais T ; et al. (2012) Identification of novel causative genes determining the complex trait of high ethanol tolerance in y[...]	GP00001088	SWS2 P53937	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SWS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SWS2	Sporulation efficiency	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Ben-Ari G; Zenvirth D; Sherman A ; et al. (2006) Four linked genes participate in controlling sporulation efficiency in budding yeast.	GP00001089	SWS2 P53937	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SWS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TAF5	Low-glucose adaptation (experimental evolution)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00001710	TAF5 P38129	Physiology	Gly693Val (G>T at position 616441 according to Table 1) - GGN to GTN position 616441	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	TAF5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TAO3	Sporulation efficiency	Cis-regulatory, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Deutschbauer AM; Davis RW (2005) Quantitative trait loci mapped to single-nucleotide resolution in yeast.	GP00001103	TAO3 P40468	Physiology	E1493Q	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	TAO3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TPD3	Cell size	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001499	TPD3 P31383	Physiology	C>T p.Q557* heterozygous nonsense mutation which may cause the larger cell size N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	TPD3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TRK1	Salt tolerance (ammonium)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Reisser C; Dick C; Kruglyak L ; et al. (2013) Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case.	GP00001139	NTRK1 P04629	Physiology	Candidate a.a substitutions in K12 : C1143S; H551P; E1190G; Q1227K	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	TRK1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TSA2	Xenobiotic resistance (hydrogen peroxide)	Gene Amplification, Complex Change	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Linkage Mapping	Linder RA; Greco JP; Seidl F ; et al. (2017) The Stress-Inducible Peroxidase TSA2 Underlies a Conditionally Beneficial Chromosomal Duplication in[...]	GP00001831	TSA2 Q04120	Physiology	Chromosome 4 whole duplication. Using a genetic mapping strategy that involves systematically deleting segments of a duplicated chromosome; the authors show that the chromosome IV’s duplication effect is largely due to the generation of a second copy of the stress-inducible cytoplasmic thioredoxin peroxidase TSA2.	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	TSA2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 1	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001290	VTC1 P40046	Physiology	G>T (Asp > Tyr) @ position 289	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 1	Metal tolerance (copper)	Coding, Indel N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001291	VTC1 P40046	Physiology	Pro > His+frameshift @ position 13 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 1	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001292	VTC1 P40046	Physiology	C>A (Ser > Stop) @ position 104 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001293	VTC4 P47075	Physiology	C>T (Trp > Stop) @ position 800 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001294	VTC4 P47075	Physiology	C>A (Glu > Stop) @ position 226 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, Indel N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001295	VTC4 P47075	Physiology	Phe > Ser+frameshift @ position 380 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001296	VTC4 P47075	Physiology	A>G (Tyr > His) @ position 1075	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001297	VTC4 P47075	Physiology	C>T (Trp > Stop) @ position 1320 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001298	VTC4 P47075	Physiology	T>A (Arg > Stop) @ position 757 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001299	VTC4 P47075	Physiology	C>A (Glu > Stop) @ position 1153 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator