18-wheeler
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Lazzaro BP; Sackton TB; Clark AG (2006)
Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.
GP00000001
18w
A1ZBR2
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
18-wheeler
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
ABC transporter pvmrp1
Xenobiotic resistance (multiresistance to antimalarial drugs)
Unknown,
Unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Intraspecific
Association Mapping
Pearson RD; Amato R; Auburn S ; et al. (2016)
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
GP00001486
PVX_097025
A5KCN4
Physiology
unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Plasmodium vivax
malaria parasite P. vivax - (species)
ABC transporter pvmrp1
Plasmodium vivax
malaria parasite P. vivax - (species)
Published - Accepted by Curator
ABCB1
Plant size (dwarfism)
Unknown,
Unknown
Cenchrus americanus
(species)
Domesticated
Linkage Mapping
Parvathaneni RK; Jakkula V; Padi FK ; et al. (2013)
Fine-mapping and identification of a candidate gene underlying the d2 dwarfing phenotype in pearl mi[...]
GP00000006
ABCB1
Q9ZR72
Morphology
unknown
Cenchrus americanus
(species)
Cenchrus americanus
(species)
ABCB1
Cenchrus americanus
(species)
Published - Accepted by Curator
ABCB7
Iron metabolism
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001379
ABCB7
O75027
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
ABCB7
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
ABCC2
Xenobiotic resistance (insecticide; Bt Cry1Ac)
Unknown,
Unknown
Trichoplusia ni
cabbage looper - (species) D
Intraspecific
Linkage Mapping
Baxter SW; Badenes-Pérez FR; Morrison A ; et al. (2011)
Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera.
GP00000014
ABCC2
A0A0E3ZDK3
Physiology
Not identified
Trichoplusia ni
cabbage looper - (species)
Trichoplusia ni
cabbage looper - (species) D
ABCC2
Trichoplusia ni
cabbage looper - (species)
Published - Accepted by Curator
ABCG2
Milk yield
Unknown,
Unknown
Ovis aries
sheep - (species)
Domesticated
Candidate Gene
García-Fernández M; Gutiérrez-Gil B; Sánchez JP ; et al. (2011)
The role of bovine causal genes underlying dairy traits in Spanish Churra sheep.
GP00000016
Abcg2
Q7TMS5
Physiology
unknown
Ovis aries
sheep - (species)
Ovis aries
sheep - (species)
ABCG2
Ovis aries
sheep - (species)
Published - Accepted by Curator
Abdominal-B
Coloration (male-specific)
Unknown,
Unknown
Drosophila malerkotliana
(species)
Intraspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001548
Abd-B
P09087
Morphology
unknown
Drosophila malerkotliana
(species)
Drosophila malerkotliana
(species)
Abdominal-B
Drosophila malerkotliana
(species)
Published - Accepted by Curator
Abdominal-B
Coloration (male-specific)
Unknown,
Unknown
Drosophila merina
(species)
Interspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001549
Abd-B
P09087
Morphology
unknown
Drosophila ercepeae
(species)
Drosophila merina
(species)
Abdominal-B
Drosophila merina
(species)
Published - Accepted by Curator
ABO histo blood group glycosyltransferase
ABO antigen blood type
Unknown,
Unknown
Pan troglodytes
chimpanzee - (species)
Intraspecific
Candidate Gene
Kermarrec N; Roubinet F; Apoil PA ; et al. (1999)
Comparison of allele O sequences of the human and non-human primate ABO system.
GP00000024
ABO
P16442
Physiology
unknown
Pan troglodytes
chimpanzee - (species)
Pan troglodytes
chimpanzee - (species)
ABO histo blood group glycosyltransferase
Pan troglodytes
chimpanzee - (species)
Published - Accepted by Curator
ADAMTS10
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000050
ADAMTS10
Q9H324
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
ADAMTS10
Homo sapiens
human - (species)
Published - Accepted by Curator
AGAMOUS-LIKE 50
Leaf number (at flowering time)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Association Mapping
Seymour DK; Chae E; Grimm DG ; et al. (2016)
Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids.
GP00001450
AGAMOUS-like 50
Q9XIE7
Morphology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
AGAMOUS-LIKE 50
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
agrecan
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000072
ACAN
P16112
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
agrecan
Homo sapiens
human - (species)
Published - Accepted by Curator
AIP
Xenobiotic resistance (pollution)
Unknown,
Unknown
N
Fundulus heteroclitus
mummichog - (species) D
Intraspecific
Association Mapping
Reid NM; Proestou DA; Clark BW ; et al. (2016)
The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish.
GP00001812
Aip
O08915
Physiology
exact mutation(s) unknown - very good candidate gene according to association mapping and knowledge about the physiology N
Fundulus heteroclitus
mummichog - (species)
Fundulus heteroclitus
mummichog - (species) D
AIP
Fundulus heteroclitus
mummichog - (species)
Published - Accepted by Curator
AIP
Xenobiotic resistance (pollution)
Unknown,
Unknown
N
Fundulus grandis
Gulf killifish - (species) D
Intraspecific
Association Mapping
Oziolor EM; Reid NM; Yair S ; et al. (2019)
Adaptive introgression enables evolutionary rescue from extreme environmental pollution.
GP00002670
Aip
O08915
Physiology
exact mutation(s) unknown - very good candidate gene according to Fst and knowledge about the physiology N
Fundulus grandis
Gulf killifish - (species)
Fundulus grandis
Gulf killifish - (species) D
AIP
Fundulus grandis
Gulf killifish - (species)
Published - Accepted by Curator
ALX1
Beak size
Unknown,
Unknown
Geospiza
(genus) D
Interspecific
Association Mapping
Lamichhaney S; Berglund J; Almén MS ; et al. (2015)
Evolution of Darwin's finches and their beaks revealed by genome sequencing.
1 Additional References
GP00000081
Alx1
Q8C8B0
Morphology
240kb haplotype with complex variation
Geospiza
(genus)
Geospiza
(genus) D
ALX1
Geospiza
(genus)
Published - Accepted by Curator
ammonium transporter 2;1
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001431
AMT2
Q9M6N7
Physiology
seven aa substitutions
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
ammonium transporter 2;1
Arabidopsis arenosa
(species)
Published - Accepted by Curator
AMPD1 (=CG32626)
Drug resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Kislukhin G; King EG; Walters KN ; et al. (2013)
The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.
GP00000083
AMPD1
P23109
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
AMPD1 (=CG32626)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
AMPD1 [clinical; candidate gene study; added for insights on fly-human parallelism]
Drug resistance
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Candidate Gene
Wessels JA; van der Kooij SM; le Cessie S ; et al. (2007)
A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset[...]
GP00000084
AMPD1
P23109
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
AMPD1 [clinical; candidate gene study; added for insights on fly-human parallelism]
Homo sapiens
human - (species)
Published - Accepted by Curator
APL1 cluster
Pathogen resistance (Plasmodium; malaria parasite)
Unknown,
Unknown
Anopheles gambiae
African malaria mosquito - (species) D
Intraspecific
Linkage Mapping
Riehle MM; Markianos K; Niaré O ; et al. (2006)
Natural malaria infection in Anopheles gambiae is regulated by a single genomic control region.
1 Additional References
GP00000098
APL1A
L7RQU1
Physiology
Not identified
Anopheles gambiae
African malaria mosquito - (species)
Anopheles gambiae
African malaria mosquito - (species) D
APL1 cluster
Anopheles gambiae
African malaria mosquito - (species)
Published - Accepted by Curator
ARNT-1c
Xenobiotic resistance (pollution)
Unknown,
Unknown
N
Fundulus grandis
Gulf killifish - (species) D
Intraspecific
Association Mapping
Oziolor EM; Reid NM; Yair S ; et al. (2019)
Adaptive introgression enables evolutionary rescue from extreme environmental pollution.
GP00002672
P27540NULL
Physiology
exact mutation(s) unknown - very good candidate gene according to high differentiation region on chromosome 8 and knowledge about the physiology. ARNT1c is a nuclear dimerization partner of aryl hydrocarbon receptor (AHR) required for activation of the xenobiotic response pathway. N
Fundulus grandis
Gulf killifish - (species)
Fundulus grandis
Gulf killifish - (species) D
ARNT-1c
Fundulus grandis
Gulf killifish - (species)
Published - Accepted by Curator
ARNT-L2a
Xenobiotic resistance (pollution)
Unknown,
Unknown
N
Fundulus grandis
Gulf killifish - (species) D
Intraspecific
Association Mapping
Oziolor EM; Reid NM; Yair S ; et al. (2019)
Adaptive introgression enables evolutionary rescue from extreme environmental pollution.
GP00002671
P27540NULL
Physiology
exact mutation(s) unknown - very good candidate gene according to high differentiation region on chromosome 10 and knowledge about the physiology. ARNT-L2a is a nuclear dimerization partner of aryl hydrocarbon receptor (AHR) required for activation of the xenobiotic response pathway. N
Fundulus grandis
Gulf killifish - (species)
Fundulus grandis
Gulf killifish - (species) D
ARNT-L2a
Fundulus grandis
Gulf killifish - (species)
Published - Accepted by Curator
asparagine synthetase (AS)
Silk yield
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002404
AsnS
Q7KTW9
Physiology
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
asparagine synthetase (AS)
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
AT5G41740/AT5G41750
Hybrid incompatibility (auto-immune necrosis)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Bomblies K; Lempe J; Epple P ; et al. (2007)
Autoimmune response as a mechanism for a Dobzhansky-Muller-type incompatibility syndrome in plants.
GP00000105
MUF8.2
F4JYI4
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
AT5G41740/AT5G41750
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
ATP2B4
Pathogen resistance (Plasmodium; malaria parasite)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Timmann C; Thye T; Vens M ; et al. (2012)
Genome-wide association study indicates two novel resistance loci for severe malaria.
GP00000127
ATP2B4
P23634
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
ATP2B4
Homo sapiens
human - (species)
Published - Accepted by Curator
ATXN1
Body fat distribution (attenuation)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001552
ATXN1
P54253
Physiology
A>G in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
ATXN1
Homo sapiens
human - (species)
Published - Accepted by Curator
bab2
Fertility (ovariole number)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Green DA; Extavour CG (2012)
Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila[...]
1 Additional References
GP00000132
bab2
Q9W0K4
Physiology
unknown ; loss of function reduces ovariole number
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
bab2
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
BAK1
Hematopoiesis (blood platelet count)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001616
BAK1
Q16611
Physiology
A>G at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
BAK1
Homo sapiens
human - (species)
Published - Accepted by Curator
Barren inflorescence2 (BIF2)
Plant architecture
Inflorescence architecture
Unknown,
Unknown
Zea mays
(species)
Domesticated
Linkage Mapping
Pressoir G; Brown PJ; Zhu W ; et al. (2009)
Natural variation in maize architecture is mediated by allelic differences at the PINOID co-ortholog[...]
1 Additional References
GP00000135
bif2
A6MW92
Morphology
Morphology
unknown
Zea mays
(species)
Zea mays
(species)
Barren inflorescence2 (BIF2)
Zea mays
(species)
Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2
Carotenoid content (sexual dichromatism, male-specific)
Unknown,
Unknown
Serinus canaria
common canary - (species)
Intergeneric or Higher
Linkage Mapping
Gazda MA; Araújo PM; Lopes RJ ; et al. (2020)
A genetic mechanism for sexual dichromatism in birds.
GP00002139
BCO2
Q9BYV7
Morphology
Gene expression study suggests a cis-regulatory difference ; and coding mutations are unlikely to be causal
Spinus cucullatus
red siskin - (species)
Serinus canaria
common canary - (species)
BCO2 = beta-carotene oxygenase 2
Serinus canaria
common canary - (species)
Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2
Coloration (feather)
Unknown,
Unknown
Setophaga petechia
yellow warbler - (species) D
Interspecific
Association Mapping
Baiz MD; Wood AW; Brelsford A ; et al. (2021)
Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setop[...]
GP00002387
BCO2
Q9BYV7
Morphology
Setophaga pensylvanica
Chestnut-sided warbler - (species)
Setophaga petechia
yellow warbler - (species) D
BCO2 = beta-carotene oxygenase 2
Setophaga petechia
yellow warbler - (species)
Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2
Coloration (feather)
Unknown,
Unknown
Setophaga citrina
hooded warbler - (species) D
Interspecific
Association Mapping
Baiz MD; Wood AW; Brelsford A ; et al. (2021)
Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setop[...]
GP00002388
BCO2
Q9BYV7
Morphology
Setophaga ruticilla
(species)
Setophaga citrina
hooded warbler - (species) D
BCO2 = beta-carotene oxygenase 2
Setophaga citrina
hooded warbler - (species)
Published - Accepted by Curator
BHLHE41
Hypoxia response
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Huerta-Sánchez E; Degiorgio M; Pagani L ; et al. (2013)
Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations.
GP00000144
BHLHE41
Q9C0J9
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
BHLHE41
Homo sapiens
human - (species)
Published - Accepted by Curator
BMP4 (uncertain)
Cranio-facial morphology
Unknown,
Unknown
Maylandia zebra
zebra mbuna - (species)
Interspecific
Linkage Mapping
Albertson RC; Streelman JT; Kocher TD ; et al. (2005)
Integration and evolution of the cichlid mandible: the molecular basis of alternate feeding strategi[...]
2 Additional References
GP00000153
bmp4
O13107
Morphology
Not identified
Labeotropheus fuelleborni
blue mbuna - (species)
Maylandia zebra
zebra mbuna - (species)
BMP4 (uncertain)
Maylandia zebra
zebra mbuna - (species)
Published - Accepted by Curator
Brassinosteroid-deficient dwarf1 (brd1)
Plant size (height)
Unknown,
Unknown
Zea mays
(species)
Intraspecific
Linkage Mapping
Peiffer JA; Romay MC; Gore MA ; et al. (2014)
The genetic architecture of maize height.
GP00001628
ZEAMMB73_Zm00001d033180
A0A1D6KWT1
Morphology
On chromosome 1 two C>T transitions reduce plant height in 18RIL families
Zea mays
(species)
Zea mays
(species)
Brassinosteroid-deficient dwarf1 (brd1)
Zea mays
(species)
Published - Accepted by Curator
brittle endosperm2 (Bt2) = endosperm ADP-glucose pyrophosphorylase small subunit
Sweet and brittle seed
Unknown,
Unknown
Zea mays
(species)
Domesticated
Linkage Mapping
Preiss J; Danner S; Summers PS ; et al. (1990)
Molecular Characterization of the Brittle-2 Gene Effect on Maize Endosperm ADPglucose Pyrophosphoryl[...]
GP00000158
bt2
Q84J79
Physiology
Not identified
Zea mays
(species)
Zea mays
(species)
brittle endosperm2 (Bt2) = endosperm ADP-glucose pyrophosphorylase small subunit
Zea mays
(species)
Published - Accepted by Curator
Brix9-2-5/LIN5 invertase
Fruit sugar content
Unknown,
Unknown
Solanum lycopersicum
tomato - (species) D
Domesticated
Linkage Mapping
Fridman E; Carrari F; Liu YS ; et al. (2004)
Zooming in on a quantitative trait for tomato yield using interspecific introgressions.
GP00000159
LIN5
P93199
Physiology
Not identified
Solanum pennellii
(species)
Solanum lycopersicum
tomato - (species) D
Brix9-2-5/LIN5 invertase
Solanum lycopersicum
tomato - (species)
Published - Accepted by Curator
calmodulin binding hydrolase
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001438
Q9FHQ0
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
calmodulin binding hydrolase
Arabidopsis arenosa
(species)
Published - Accepted by Curator
Camta3
Plant size (height)
Unknown,
Unknown
Zea mays
(species)
Intraspecific
Association Mapping
Peiffer JA; Romay MC; Gore MA ; et al. (2014)
The genetic architecture of maize height.
GP00001629
CAMTA3
Q8GSA7
Morphology
C>T transition on chromosome 3
Zea mays
(species)
Zea mays
(species)
Camta3
Zea mays
(species)
Published - Accepted by Curator
Casparian strip membrane domain protein 1
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001432
CASP1
Q9SIH4
Physiology
five aa sustitutions
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
Casparian strip membrane domain protein 1
Arabidopsis arenosa
(species)
Published - Accepted by Curator
CBF gene cluster
Temperature tolerance (cold)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Gery C; Zuther E; Schulz E ; et al. (2011)
Natural variation in the freezing tolerance of Arabidopsis thaliana: effects of RNAi-induced CBF dep[...]
GP00000174
B1NSN2
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
CBF gene cluster
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
ccdc170
Coloration
Unknown,
Unknown
Anolis sagrei
Brown anole - (species)
Intraspecific
Association Mapping
Feiner N; Brun-Usan M; Andrade P ; et al. (2022)
A single locus regulates a female-limited color pattern polymorphism in a reptile.
GP00002363
Ccdc170
D3YXL0
Morphology
Anolis sagrei
Brown anole - (species)
Anolis sagrei
Brown anole - (species)
ccdc170
Anolis sagrei
Brown anole - (species)
Published - Accepted by Curator
CEP55
Recombination rate (female)
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001667
CEP55
E1B8M0
Physiology
Associated SNP located near the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
CEP55
Bos taurus
cattle - (species)
Published - Accepted by Curator
CG8492
Pathogen resistance (Drosophila C virus & flock house virus)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Experimental Evolution
Association Mapping
Martins NE; Faria VG; Nolte V ; et al. (2014)
Host adaptation to viruses relies on few genes with different cross-resistance properties.
GP00001481
Dmel\CG8492
Q9VSA5
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
CG8492
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Chalcone synthase D (CHS-D)
Coloration (flower)
Unknown,
Insertion
Ipomoea purpurea
common morning-glory - (species) D
Intraspecific
Candidate Gene
Habu Y; Hisatomi Y; Iida S (1998)
Molecular characterization of the mutable flaked allele for flower variegation in the common morning[...]
GP00001459
CHSD
O22045
Morphology
insertion of a 3.9kb long transposable element Tip100 in intron
Ipomoea purpurea
common morning-glory - (species)
Ipomoea purpurea
common morning-glory - (species) D
Chalcone synthase D (CHS-D)
Ipomoea purpurea
common morning-glory - (species)
Published - Accepted by Curator
Chalcone synthase D (CHS-D)
Coloration (flower)
Unknown,
Insertion
Ipomoea purpurea
common morning-glory - (species) D
Intraspecific
Candidate Gene
Habu Y; Hisatomi Y; Iida S (1998)
Molecular characterization of the mutable flaked allele for flower variegation in the common morning[...]
GP00001460
CHSD
O22045
Morphology
2 insertions of Tip100 in opposite orientation at different sites within the same intron
Ipomoea purpurea
common morning-glory - (species)
Ipomoea purpurea
common morning-glory - (species) D
Chalcone synthase D (CHS-D)
Ipomoea purpurea
common morning-glory - (species)
Published - Accepted by Curator
CHRNA3/5 nicotine receptor cluster
Aging
Smoking behavior
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Joshi PK; Fischer K; Schraut KE ; et al. (2016)
Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.
GP00000185
CHRNA3
P32297
Physiology
Physiology
unknown; complex variation with SNP association signal
Homo sapiens
human - (species)
Homo sapiens
human - (species)
CHRNA3/5 nicotine receptor cluster
Homo sapiens
human - (species)
Published - Accepted by Curator
CLH1
Xenobiotic resistance (fungicide: guazatine)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Association Mapping
Atanasov KE; Barboza-Barquero L; Tiburcio AF ; et al. (2016)
Genome Wide Association Mapping for the Tolerance to the Polyamine Oxidase Inhibitor Guazatine in Ar[...]
GP00001234
CLH1
O22527
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
CLH1
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
Clock
Circadian rhythm
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002409
Clk
O61735
Physiology
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
Clock
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
cortex
Coloration (wing ; body)
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species)
Domesticated
Linkage Mapping
Ito K; Katsuma S; Kuwazaki S ; et al. (2016)
Mapping and recombination analysis of two moth colour mutations, Black moth and Wild wing spot, in t[...]
GP00002417
cort
Q960N3
Morphology
Mapping to a 2-Mb-long region which contains the cortex gene.
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species)
cortex
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
cortex
Coloration (wing)
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species)
Domesticated
Linkage Mapping
Ito K; Katsuma S; Kuwazaki S ; et al. (2016)
Mapping and recombination analysis of two moth colour mutations, Black moth and Wild wing spot, in t[...]
GP00002418
cort
Q960N3
Morphology
Mapping to a 100-kb-long region which contains the cortex gene.
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species)
cortex
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
cortex
Coloration (wing; mimicry)
Unknown,
Unknown
Papilio clytia
common mime swallowtail - (species)
Intraspecific
Association Mapping
VanKuren NW; Massardo D; Nallu S ; et al. (2019)
Butterfly Mimicry Polymorphisms Highlight Phylogenetic Limits of Gene Reuse in the Evolution of Dive[...]
GP00002419
cort
Q960N3
Morphology
Mapping to a 500-kb region that contains the cortex gene
Papilio clytia
common mime swallowtail - (species)
Papilio clytia
common mime swallowtail - (species)
cortex
Papilio clytia
common mime swallowtail - (species)
Published - Accepted by Curator
CPLX1
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001659
CPLX1
Q0IIL7
Physiology
On chromosome 6. Associated SNP in the intron of the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
CPLX1
Bos taurus
cattle - (species)
Published - Accepted by Curator
Cryptochrome 2 (CRY2)
Circadian rhythm
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002408
cry
O77059
Physiology
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
Cryptochrome 2 (CRY2)
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
CYP2J19
Coloration (feathers)
Unknown,
Unknown
Serinus canaria
common canary - (species)
Interspecific
Linkage Mapping
Lopes RJ; Johnson JD; Toomey MB ; et al. (2016)
Genetic Basis for Red Coloration in Birds.
GP00000201
CYP2J2
P51589
Morphology
unknown
Spinus cucullatus
red siskin - (species)
Serinus canaria
common canary - (species)
CYP2J19
Serinus canaria
common canary - (species)
Published - Accepted by Curator
Darkener of apricot (Doa)
Lifespan
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Association Mapping
Hoedjes KM; Kostic H; Keller L ; et al. (2022)
Natural alleles at the Doa locus underpin evolutionary changes in Drosophila lifespan and fecundity.
GP00002662
Doa
P49762
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
Darkener of apricot (Doa)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Dat
Coloration (puparium)
Unknown,
Unknown
Drosophila virilis
(species)
Interspecific
Linkage Mapping
Ahmed-Braimah YH; Sweigart AL (2015)
A single gene causes an interspecific difference in pigmentation in Drosophila.
GP00001403
AANAT1
Q94521
Morphology
unknown
Drosophila americana
(species)
Drosophila virilis
(species)
Dat
Drosophila virilis
(species)
Published - Accepted by Curator
DC-STAMP domain containing 2 (DCST2)
Body size
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
van der Valk RJ; Kreiner-Møller E; Kooijman MN ; et al. (2015)
A novel common variant in DCST2 is associated with length in early life and height in adulthood.
GP00001509
DCST2
Q5T1A1
Morphology
SNP rs905938 C allele associated with an increase in birth length but probably not the causative mutation
Homo sapiens
human - (species)
Homo sapiens
human - (species)
DC-STAMP domain containing 2 (DCST2)
Homo sapiens
human - (species)
Published - Accepted by Curator
DCAF17
Hair Length
Unknown,
Unknown
Sus scrofa
pig - (species) D
Domesticated
Association Mapping
Ai H; Fang X; Yang B ; et al. (2015)
Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequen[...]
GP00001570
DCAF17
I3LQF0
Physiology
Sus scrofa
pig - (species)
Sus scrofa
pig - (species) D
DCAF17
Sus scrofa
pig - (species)
Published - Accepted by Curator
Dihydrofolate reductase (pvdhfr)
Xenobiotic resistance (pyrimethamine)
Unknown,
Unknown
Plasmodium vivax
malaria parasite P. vivax - (species) D
Intraspecific
Association Mapping
Pearson RD; Amato R; Auburn S ; et al. (2016)
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
GP00001484
DHFR
P00374
Physiology
unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Plasmodium vivax
malaria parasite P. vivax - (species) D
Dihydrofolate reductase (pvdhfr)
Plasmodium vivax
malaria parasite P. vivax - (species)
Published - Accepted by Curator
Dihydropteroate synthase (pvdhps)
Xenobiotic resistance (sulfadoxine)
Unknown,
Unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Intraspecific
Association Mapping
Pearson RD; Amato R; Auburn S ; et al. (2016)
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
GP00001485
DHPS
Q00LX9
Physiology
unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Plasmodium vivax
malaria parasite P. vivax - (species)
Dihydropteroate synthase (pvdhps)
Plasmodium vivax
malaria parasite P. vivax - (species)
Published - Accepted by Curator
Dopa oxidase-3 (Dox-3)
Enzymatic activity
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Intraspecific
Candidate Gene
Asada N (1997)
Genetic variants affecting phenoloxidase activity in Drosophila melanogaster.
GP00002000
Physiology
Exact causing mutation(s) unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
Dopa oxidase-3 (Dox-3)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Dopa-decarboxylase
Lifespan
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
De Luca M; Roshina NV; Geiger-Thornsberry GL ; et al. (2003)
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity.
GP00000233
Ddc
P05031
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
Dopa-decarboxylase
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Dopamine N-acetyltransferase (Dat)
Coloration (puparium)
Unknown,
Unknown
Drosophila virilis
(species) D
Interspecific
Linkage Mapping
Ahmed-Braimah YH; Sweigart AL (2015)
A single gene causes an interspecific difference in pigmentation in Drosophila.
GP00000234
AANAT1
Q94521
Morphology
Not identified ; 11kb mapped interval including regulatory region and first exon
Drosophila americana
(species)
Drosophila virilis
(species) D
Dopamine N-acetyltransferase (Dat)
Drosophila virilis
(species)
Published - Accepted by Curator
Doublesex
Coloration (wing ; Batesian mimicry)
Unknown,
Unknown
Papilio polytes
common Mormon - (species)
Intraspecific
Linkage Mapping
Kunte K; Zhang W; Tenger-Trolander A ; et al. (2014)
doublesex is a mimicry supergene.
2 Additional References
GP00001966
dsx
P23023
Morphology
More than 1000 nucleotide substitutions differentiate mimetic and non-mimetic dsx alleles. The non-mimetic Cyrus Dsx protein folds much like other insects (such as Bombyx mori) whereas the mimetic polytes protein structure is highly divergent. Knockdown experiments show that female-specific dsx isoforms expressed from the inverted H allele (dsx(H)) induce mimetic coloration patterns and simultaneously repress non-mimetic patterns.
Papilio polytes
common Mormon - (species)
Papilio polytes
common Mormon - (species)
Doublesex
Papilio polytes
common Mormon - (species)
Published - Accepted by Curator
Doublesex
Coloration (wing ; Batesian mimicry)
Unknown,
Unknown
Papilio memnon
(species)
Intraspecific
Candidate Gene
Iijima T; Kajitani R; Komata S ; et al. (2018)
Parallel evolution of Batesian mimicry supergene in two Papilio butterflies, P. polytes and P. memno[...]
1 Additional References
GP00001967
dsx
P23023
Morphology
A locus containing three genes (dsx; Nach-like and UXT) displays dimorphic sequences strictly associated with the mimetic/nonmimetic phenotypes. Expression of dox; UXT but not Nach-like showed differences correlated with phenotype in female hind wings.
Papilio memnon
(species)
Papilio memnon
(species)
Doublesex
Papilio memnon
(species)
Published - Accepted by Curator
ds1
Pathogen resistance
Unknown,
Unknown
Sorghum bicolor
sorghum - (species)
Domesticated
Linkage Mapping
Kawahigashi H; Kasuga S; Ando T ; et al. (2011)
Positional cloning of ds1, the target leaf spot resistance gene against Bipolaris sorghicola in sorg[...]
GP00000238
ds1
K0IXC4
Physiology
unknown
Sorghum bicolor
sorghum - (species)
Sorghum bicolor
sorghum - (species)
ds1
Sorghum bicolor
sorghum - (species)
Published - Accepted by Curator
DYM
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000242
DYM
Q7RTS9
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
DYM
Homo sapiens
human - (species)
Published - Accepted by Curator
EARLY FLOWERING 3/Hd17
Flowering time
Unknown,
Unknown
Oryza sativa
rice - (species)
Domesticated
Linkage Mapping
Matsubara K; Ogiso-Tanaka E; Hori K ; et al. (2012)
Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flow[...]
GP00000247
ELF3
O82804
Physiology
unknown
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
EARLY FLOWERING 3/Hd17
Oryza sativa
rice - (species)
Published - Accepted by Curator
early responsive to dehydration stress protein 4
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001434
ERD4
Q9C8G5
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
early responsive to dehydration stress protein 4
Arabidopsis arenosa
(species)
Published - Accepted by Curator
EBF1
Body fat distribution (pericardial)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001554
EBF1
Q9UH73
Physiology
A>G & T>G in 2 associated SNPs
Homo sapiens
human - (species)
Homo sapiens
human - (species)
EBF1
Homo sapiens
human - (species)
Published - Accepted by Curator
ebony
Coloration (male-specific)
Unknown,
Unknown
Drosophila merina
(species)
Interspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001546
e
O76858
Morphology
unknown
Drosophila ercepeae
(species)
Drosophila merina
(species)
ebony
Drosophila merina
(species)
Published - Accepted by Curator
ebony
Coloration (male-specific)
Unknown,
Unknown
Drosophila bipectinata
(species)
Interspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001547
e
O76858
Morphology
unknown
Drosophila parabipectinata
(species)
Drosophila bipectinata
(species)
ebony
Drosophila bipectinata
(species)
Published - Accepted by Curator
EDN3
Coloration (coat)
Coloration (eyes)
Hearing (loss)
Unknown,
Unknown
Lama glama
llama - (species) D
Vicugna pacos
alpaca - (species) D
Domesticated
Candidate Gene
Fan R; Gu Z; Guang X ; et al. (2020)
Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca.
GP00002182
EDN3
P14138
Morphology
Morphology
Physiology
Introgression from alpacas to lamas and clear correlation wit phenotype but no information on the mutation(s)
Vicugna vicugna
vicugna - (species)
Lama glama
llama - (species) D
Vicugna pacos
alpaca - (species) D
EDN3
Lama glama
llama - (species)
Vicugna pacos
alpaca - (species)
Published - Accepted by Curator
EGFR
Wing shape (length)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Dworkin I; Palsson A; Gibson G (2005)
Replication of an Egfr-wing shape association in a wild-caught cohort of Drosophila melanogaster.
1 Additional References
GP00000259
Egfr
P04412
Morphology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
EGFR
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
EGFR
Coloration (skin)
Unknown,
Unknown
Homo sapiens
human - (species) D
Intraspecific
Association Mapping
Quillen EE; Bauchet M; Bigham AW ; et al. (2012)
OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and European[...]
GP00001537
EGFR
P00533
Morphology
A>T associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species) D
EGFR
Homo sapiens
human - (species)
Published - Accepted by Curator
egl-4 (Ppa-egl-4)
Insect pheromone attraction
Unknown,
Unknown
Pristionchus pacificus
(species)
Intraspecific
Association Mapping
Hong RL; Witte H; Sommer RJ (2008)
Natural variation in Pristionchus pacificus insect pheromone attraction involves the protein kinase [...]
GP00000260
egl-4
O76360
Behavior
unknown
Pristionchus pacificus
(species)
Pristionchus pacificus
(species)
egl-4 (Ppa-egl-4)
Pristionchus pacificus
(species)
Published - Accepted by Curator
EGLN1
Hypoxia response
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Bigham A; Bauchet M; Pinto D ; et al. (2010)
Identifying signatures of natural selection in Tibetan and Andean populations using dense genome sca[...]
GP00000262
EGLN1
Q9GZT9
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
EGLN1
Homo sapiens
human - (species)
Published - Accepted by Curator
EGLN1
High-altitude adaptation
Hypoxia response
Unknown,
Unknown
Anas flavirostris
Yellow-billed teal - (species) D
Intraspecific
Candidate Gene
Graham AM; McCracken KG (2019)
Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]
GP00002135
EGLN1
Q9GZT9
Physiology
Physiology
probably cis-regulatory because no nonsynonymous mutations in the coding exon with high Fst
Anas flavirostris
Yellow-billed teal - (species)
Anas flavirostris
Yellow-billed teal - (species) D
EGLN1
Anas flavirostris
Yellow-billed teal - (species)
Published - Accepted by Curator
EGLN1
High-altitude adaptation
Hypoxia response
Unknown,
Unknown
Anas georgica
yellow-billed pintail - (species) D
Intraspecific
Candidate Gene
Graham AM; McCracken KG (2019)
Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]
GP00002136
EGLN1
Q9GZT9
Physiology
Physiology
probably cis-regulatory because no nonsynonymous mutations in the coding exon with high Fst
Anas georgica
yellow-billed pintail - (species)
Anas georgica
yellow-billed pintail - (species) D
EGLN1
Anas georgica
yellow-billed pintail - (species)
Published - Accepted by Curator
EIF2AK3
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000264
EIF2AK3
Q9NZJ5
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
EIF2AK3
Homo sapiens
human - (species)
Published - Accepted by Curator
EIF2S2
Coloration (skin)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Liu F; Visser M; Duffy DL ; et al. (2015)
Genetics of skin color variation in Europeans: genome-wide association studies with functional follo[...]
GP00001359
EIF2S2
P20042
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
EIF2S2
Homo sapiens
human - (species)
Published - Accepted by Curator
ENSA
Body fat distribution (pericardial)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001558
ENSA
O43768
Physiology
A>G in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
ENSA
Homo sapiens
human - (species)
Published - Accepted by Curator
EPAS1
Hypoxia response
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Simonson TS; Yang Y; Huff CD ; et al. (2010)
Genetic evidence for high-altitude adaptation in Tibet.
1 Additional References
GP00000274
EPAS1
Q99814
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
EPAS1
Homo sapiens
human - (species)
Published - Accepted by Curator
EPAS1
High-altitude adaptation
Hypoxia response
Unknown,
Unknown
Anas cyanoptera
cinnamon teal - (species) D
Intraspecific
Candidate Gene
Graham AM; McCracken KG (2019)
Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]
GP00002131
EPAS1
Q99814
Physiology
Physiology
several candidate coding mutations
Anas cyanoptera
cinnamon teal - (species)
Anas cyanoptera
cinnamon teal - (species) D
EPAS1
Anas cyanoptera
cinnamon teal - (species)
Published - Accepted by Curator
EPAS1
High-altitude adaptation
Hypoxia response
Unknown,
Unknown
Anas flavirostris
Yellow-billed teal - (species) D
Intraspecific
Candidate Gene
Graham AM; McCracken KG (2019)
Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]
GP00002132
EPAS1
Q99814
Physiology
Physiology
several candidate coding mutations
Anas flavirostris
Yellow-billed teal - (species)
Anas flavirostris
Yellow-billed teal - (species) D
EPAS1
Anas flavirostris
Yellow-billed teal - (species)
Published - Accepted by Curator
EPAS1
High-altitude adaptation
Hypoxia response
Unknown,
Unknown
Anas georgica
yellow-billed pintail - (species) D
Intraspecific
Candidate Gene
Graham AM; McCracken KG (2019)
Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]
GP00002133
EPAS1
Q99814
Physiology
Physiology
several candidate coding mutations
Anas georgica
yellow-billed pintail - (species)
Anas georgica
yellow-billed pintail - (species) D
EPAS1
Anas georgica
yellow-billed pintail - (species)
Published - Accepted by Curator
ephrin-a4
Coloration (scales)
Unknown,
Unknown
Tropheops sp. 'red cheek'
(species)
Interspecific
Linkage Mapping
Albertson RC; Powder KE; Hu Y ; et al. (2014)
Genetic basis of continuous variation in the levels and modular inheritance of pigmentation in cichl[...]
GP00001420
EFNA4
P52798
Morphology
unknown
Labeotropheus fuelleborni
blue mbuna - (species)
Tropheops sp. 'red cheek'
(species)
ephrin-a4
Tropheops sp. 'red cheek'
(species)
Published - Accepted by Curator
ERECTA
Plant architecture
Leaf architecture
Transpiration
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Masle J; Gilmore SR; Farquhar GD (2005)
The ERECTA gene regulates plant transpiration efficiency in Arabidopsis.
2 Additional References
GP00000280
ERECTA
Q42371
Morphology
Morphology
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
ERECTA
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
ERECTA
Pathogen resistance (Cucumerina fungus)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Llorente F; Alonso-Blanco C; Sánchez-Rodriguez C ; et al. (2005)
ERECTA receptor-like kinase and heterotrimeric G protein from Arabidopsis are required for resistanc[...]
GP00001244
ERECTA
Q42371
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
ERECTA
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
F2RL2
Hematopoiesis (mean blood platelet volume)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001617
F2RL2
O00254
Physiology
A>T at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
F2RL2
Homo sapiens
human - (species)
Published - Accepted by Curator
Fas2
Pupation site choice
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Pischedda A; Shahandeh MP; Turner TL (2020)
The Loci of Behavioral Evolution: Evidence That Fas2 and tilB Underlie Differences in Pupation Site [...]
GP00002345
Fas2
P34082
Behavior
Gene identified via deficiency mapping. RNAi in D. melanogaster leads to pupae pupating closer to the food.
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
Fas2
Drosophila simulans
(species)
Published - Accepted by Curator
FASCIATED EAR2
Grain yield (kernel row number)
Unknown,
Unknown
Zea mays
(species)
Domesticated
Linkage Mapping
Bommert P; Nagasawa NS; Jackson D (2013)
Quantitative variation in maize kernel row number is controlled by the FASCIATED EAR2 locus.
GP00000306
FEA2
Q940E8
Morphology
Not identified
Zea mays
(species)
Zea mays
(species)
FASCIATED EAR2
Zea mays
(species)
Published - Accepted by Curator
fatty acyl-CoA reductase FAR2-B
Pheromone production (cuticular hydrocarbons)
Unknown,
Unknown
Drosophila serrata
(species)
Intraspecific
Linkage Mapping
Rusuwa BB; Chung H; Allen SL ; et al. (2022)
Natural variation at a single gene generates sexual antagonism across fitness components in Drosophi[...]
GP00002395
Dmel\CG17560
Q9VES6
Physiology
Both alleles of DsFAR2-B appear to be functional. The distinction between the two alleles iss a large number of non-synonymous substitutions.
Drosophila serrata
(species)
Drosophila serrata
(species)
fatty acyl-CoA reductase FAR2-B
Drosophila serrata
(species)
Published - Accepted by Curator
Ferroportin 2
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001437
IREG2
F4KGN5
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
Ferroportin 2
Arabidopsis arenosa
(species)
Published - Accepted by Curator
FGF4 retrogene
Limb size
Unknown,
Insertion
Canis lupus familiaris
dog - (subspecies) D
Domesticated
Association Mapping
Parker HG; VonHoldt BM; Quignon P ; et al. (2009)
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.
GP00000309
FGF4
J9P3I7
Morphology
Gene retroposition : 5kb insertion containing a FGF4 retrogene; 25Mb away from the complete (original) FGF4 gene
Canis lupus
gray wolf - (species)
Canis lupus familiaris
dog - (subspecies) D
FGF4 retrogene
Canis lupus familiaris
dog - (subspecies)
Published - Accepted by Curator
Fidgetin-like1 (Fignl1)
Testis size (testis weight ; spermatogenesis)
Unknown,
Unknown
Mus musculus
house mouse - (species)
Interspecific
Linkage Mapping
L'Hôte D; Vatin M; Auer J ; et al. (2011)
Fidgetin-like1 is a strong candidate for a dynamic impairment of male meiosis leading to reduced tes[...]
GP00001668
Fignl1
Q8BPY9
Physiology
Several non-synonymous SNPs and an alternative splicing encoding a truncated isoform that may act as a competitor of the full length protein in the degradation process
Mus spretus
western wild mouse - (species)
Mus musculus
house mouse - (species)
Fidgetin-like1 (Fignl1)
Mus musculus
house mouse - (species)
Published - Accepted by Curator
Flavonoid 3'-5'-hydroxylase (F3'5'H)
Plant secondary metabolite (catechin)
Unknown,
Unknown
Camellia sinensis
(species)
Intraspecific
Linkage Mapping
Jin JQ; Ma JQ; Yao MZ ; et al. (2017)
Functional natural allelic variants of flavonoid 3',5'-hydroxylase gene governing catechin traits in[...]
GP00001620
F3'5'H1
A3KLR7
Physiology
several candidate SNPs
Camellia sinensis
(species)
Camellia sinensis
(species)
Flavonoid 3'-5'-hydroxylase (F3'5'H)
Camellia sinensis
(species)
Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)
Coloration (flowers)
Unknown,
Unknown
Petunia x hybrida
(species)
Domesticated
Candidate Gene
Brugliera F; Barri-Rewell G; Holton TA ; et al. (1999)
Isolation and characterization of a flavonoid 3'-hydroxylase cDNA clone corresponding to the Ht1 loc[...]
GP00000320
CYP75B1
Q9SD85
Morphology
Not identified
Petunia x hybrida
(species)
Petunia x hybrida
(species)
flavonoid 3'-hydroxylase (F3'H)
Petunia x hybrida
(species)
Published - Accepted by Curator
FMN1
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001662
FMN1
Q68DA7
Physiology
On chromosome 10. Associated SNP located upstream of the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
FMN1
Bos taurus
cattle - (species)
Published - Accepted by Curator
foraging
Food-search behavior
Unknown,
Unknown
Sesamia nonagrioides
Mediterranean corn borer - (species)
Intraspecific
Candidate Gene
Chardonnet F; Capdevielle-Dulac C; Chouquet B ; et al. (2014)
Food searching behaviour of a Lepidoptera pest species is modulated by the foraging gene polymorphis[...]
GP00002619
for
Q03043
Behavior
Association between a coding SNP in foraging gene and foraging activity. But not clear whether the causal mutation is this one.
Sesamia nonagrioides
Mediterranean corn borer - (species)
Sesamia nonagrioides
Mediterranean corn borer - (species)
foraging
Sesamia nonagrioides
Mediterranean corn borer - (species)
Published - Accepted by Curator
foxo
Body size (wing)
Starvation resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Betancourt NJ; Rajpurohit S; Durmaz E ; et al. (2021)
Allelic polymorphism at foxo contributes to local adaptation in Drosophila melanogaster.
1 Additional References
GP00002661
foxo
Q95V55
Morphology
Morphology; Physiology
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
foxo
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Frigida (BnaA.FRI.a)
Flowering time
Unknown,
Unknown
Brassica napus
rape - (species)
Domesticated
Linkage Mapping
Wang N; Qian W; Suppanz I ; et al. (2011)
Flowering time variation in oilseed rape (Brassica napus L.) is associated with allelic variation in[...]
GP00000356
FRI
P0DH90
Physiology
unknown
Brassica napus
rape - (species)
Brassica napus
rape - (species)
Frigida (BnaA.FRI.a)
Brassica napus
rape - (species)
Published - Accepted by Curator
FTO
Body fat distribution (subcutaneous)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001560
FTO
Q9C0B1
Physiology
A>G in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
FTO
Homo sapiens
human - (species)
Published - Accepted by Curator
G protein-coupled receptor rhodopsin
Diapause
Unknown,
Unknown
Daphnia magna
(species)
Intraspecific
Linkage Mapping
Roulin AC; Bourgeois Y; Stiefel U ; et al. (2016)
A Photoreceptor Contributes to the Natural Variation of Diapause Induction in Daphnia magna.
GP00001539
RHO
P08100
Physiology
unknown
Daphnia magna
(species)
Daphnia magna
(species)
G protein-coupled receptor rhodopsin
Daphnia magna
(species)
Published - Accepted by Curator
GCLM
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001664
GCLM
Q2T9Y6
Physiology
On chromosome 3. Associated SNP upstream of the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
GCLM
Bos taurus
cattle - (species)
Published - Accepted by Curator
GDF5
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Sanna S; Jackson AU; Nagaraja R ; et al. (2008)
Common variants in the GDF5-UQCC region are associated with variation in human height.
1 Additional References
GP00000387
GDF5
P43026
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GDF5
Homo sapiens
human - (species)
Published - Accepted by Curator
gfzf
Hybrid incompatibility (F1 male lethality)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Phadnis N; Baker EP; Cooper JC ; et al. (2015)
An essential cell cycle regulation gene causes hybrid inviability in Drosophila.
GP00000392
gfzf
Q6NP69
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
gfzf
Drosophila simulans
(species)
Published - Accepted by Curator
Ghd7
Flowering time
Inflorescence morphology
Unknown,
Unknown
Oryza sativa
rice - (species)
Domesticated
Linkage Mapping
Xue W; Xing Y; Weng X ; et al. (2008)
Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice.
GP00000393
GHD7
E5RQA1
Physiology
Morphology
unknown
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
Ghd7
Oryza sativa
rice - (species)
Published - Accepted by Curator
GHSR
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000394
GHSR
Q92847
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GHSR
Homo sapiens
human - (species)
Published - Accepted by Curator
GIBBERELLIC ACID REQUIRING 1 (GA1)
Flower morphology
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Brock MT; Kover PX; Weinig C (2012)
Natural variation in GA1 associates with floral morphology in Arabidopsis thaliana.
GP00000395
GA1
Q38802
Morphology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
GIBBERELLIC ACID REQUIRING 1 (GA1)
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
GLABROUS1
Trichome (leaves)
Unknown,
Unknown
Arabidopsis
(genus)
Intraspecific
Candidate Gene
Hauser MT; Harr B; Schlötterer C (2001)
Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...]
1 Additional References
GP00000398
GL1
P27900
Morphology
unknown
Arabidopsis
(genus)
Arabidopsis
(genus)
GLABROUS1
Arabidopsis
(genus)
Published - Accepted by Curator
GLABROUS1
Trichome density (leaf)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Association Mapping
Hauser MT; Harr B; Schlötterer C (2001)
Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...]
1 Additional References
GP00001242
GL1
P27900
Morphology
high frequency pattern of polymorphism identified in the third exon and 3' flank
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
GLABROUS1
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
glutamate dehydrogenase (GDH)
Silk yield
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002406
bb8
Q9VCN3
Physiology
Increased expression in the domesticated strains
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
glutamate dehydrogenase (GDH)
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
glutamate synthase (GOGAT)
Silk yield
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002407
GS
M9NFH8
Physiology
Increased expression in the domesticated strains at the larval stage
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
glutamate synthase (GOGAT)
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
glutamine synthetase 2 (GS)
Silk yield
Unknown,
Unknown
Bombyx mori
domestic silkworm - (species) D
Domesticated
Association Mapping
Xiang H; Liu X; Li M ; et al. (2018)
The evolutionary road from wild moth to domestic silkworm.
1 Additional References
GP00002405
Gs2
P20478
Physiology
Bombyx mori
domestic silkworm - (species)
Bombyx mori
domestic silkworm - (species) D
glutamine synthetase 2 (GS)
Bombyx mori
domestic silkworm - (species)
Published - Accepted by Curator
Glycophorin GYPA-GYPB-GYPE cluster
Pathogen resistance (Plasmodium; malaria parasite)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
; Band G; Rockett KA ; et al. (2015)
A novel locus of resistance to severe malaria in a region of ancient balancing selection.
GP00000406
GYPA
P02724
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
Glycophorin GYPA-GYPB-GYPE cluster
Homo sapiens
human - (species)
Published - Accepted by Curator
GNBP1
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Sackton TB; Lazzaro BP; Clark AG (2010)
Genotype and gene expression associations with immune function in Drosophila.
GP00000408
GNBP1
Q9NHB0
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
GNBP1
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
GNBP2
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Sackton TB; Lazzaro BP; Clark AG (2010)
Genotype and gene expression associations with immune function in Drosophila.
GP00000409
GNBP2
Q9VVR4
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
GNBP2
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
GPR133
Body size (height; male-limited)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Tönjes A; Koriath M; Schleinitz D ; et al. (2009)
Genetic variation in GPR133 is associated with height: genome wide association study in the self-con[...]
GP00000412
ADGRD1
Q6QNK2
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GPR133
Homo sapiens
human - (species)
Published - Accepted by Curator
GRAMD3
Body fat distribution (visceral)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001557
GRAMD2B
Q96HH9
Physiology
A>C in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GRAMD3
Homo sapiens
human - (species)
Published - Accepted by Curator
GSDMB
Body fat distribution (subcutaneous)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001556
GSDMB
Q8TAX9
Physiology
T>C in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GSDMB
Homo sapiens
human - (species)
Published - Accepted by Curator
GSS (glutathione synthetase)
Coloration (skin)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Liu F; Visser M; Duffy DL ; et al. (2015)
Genetics of skin color variation in Europeans: genome-wide association studies with functional follo[...]
GP00001362
GSS
P48637
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
GSS (glutathione synthetase)
Homo sapiens
human - (species)
Published - Accepted by Curator
GSTE1-E10 cluster
Xenobiotic resistance (drug)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Kislukhin G; King EG; Walters KN ; et al. (2013)
The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.
GP00000419
GstE1
Q7KK90
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
GSTE1-E10 cluster
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
HAC1 (=ATQ1)
Xenobiotic resistance (soil contamination; arsenate)
Unknown,
Complex Change
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Sánchez-Bermejo E; Castrillo G; del Llano B ; et al. (2014)
Natural variation in arsenate tolerance identifies an arsenate reductase in Arabidopsis thaliana.
1 Additional References
GP00000434
HAC1
Q9C5X9
Physiology
Coding variation and differential gene expression in roots
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
HAC1 (=ATQ1)
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
hairy (h)
Bristle number (thorax)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Robin C; Lyman RF; Long AD ; et al. (2002)
hairy: A quantitative trait locus for drosophila sensory bristle number.
GP00000436
h
P14003
Morphology
unknown; complex promoter indel variation shows high-association
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
hairy (h)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
HBS1L-MYB
Hematopoiesis (blood platelet count)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001614
HBS1L
Q9Y450
Physiology
T>C at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
HBS1L-MYB
Homo sapiens
human - (species)
Published - Accepted by Curator
heavy metal atpase4 (HMA4)
Metal tolerance
Unknown,
Unknown
Arabidopsis halleri
(species) D
Interspecific
Linkage Mapping
Courbot M; Willems G; Motte P ; et al. (2007)
A major quantitative trait locus for cadmium tolerance in Arabidopsis halleri colocalizes with HMA4,[...]
GP00000447
HMA4
O64474
Physiology
unknown
Arabidopsis lyrata
(species)
Arabidopsis halleri
(species) D
heavy metal atpase4 (HMA4)
Arabidopsis halleri
(species)
Published - Accepted by Curator
high expression of osmotically responsive genes 2
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001435
SAL1
Q42546
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
high expression of osmotically responsive genes 2
Arabidopsis arenosa
(species)
Published - Accepted by Curator
HLA-DRB1
Pathogen resistance (typhoid fever)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Dunstan SJ; Hue NT; Han B ; et al. (2014)
Variation at HLA-DRB1 is associated with resistance to enteric fever.
GP00000479
HLA-DRB1
Q30167
Physiology
uncharacterized
Homo sapiens
human - (species)
Homo sapiens
human - (species)
HLA-DRB1
Homo sapiens
human - (species)
Published - Accepted by Curator
HM1 = HC toxin reductase (HCTR)
Pathogen resistance
Unknown,
Unknown
Zea mays
(species)
Domesticated
Candidate Gene
Multani DS; Meeley RB; Paterson AH ; et al. (1998)
Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.
GP00000480
hm1
O49163
Physiology
Not identified
Zea mays
(species)
Zea mays
(species)
HM1 = HC toxin reductase (HCTR)
Zea mays
(species)
Published - Accepted by Curator
HMGA2
Body size
Unknown,
Unknown
Canis lupus familiaris
dog - (subspecies) D
Domesticated
Association Mapping
Akey JM; Ruhe AL; Akey DT ; et al. (2010)
Tracking footprints of artificial selection in the dog genome.
1 Additional References
GP00000484
HMGA2
P52926
Morphology
unknown
Canis lupus
gray wolf - (species)
Canis lupus familiaris
dog - (subspecies) D
HMGA2
Canis lupus familiaris
dog - (subspecies)
Published - Accepted by Curator
HMGA2
Body size
Unknown,
Unknown
Equus caballus
horse - (species)
Domesticated
Association Mapping
Makvandi-Nejad S; Hoffman GE; Allen JJ ; et al. (2012)
Four loci explain 83% of size variation in the horse.
GP00000485
HMGA2
P52926
Morphology
unknown
Equus caballus
horse - (species)
Equus caballus
horse - (species)
HMGA2
Equus caballus
horse - (species)
Published - Accepted by Curator
HMGA2
Body size (height; bone mineral density)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Weedon MN; Lettre G; Freathy RM ; et al. (2007)
A common variant of HMGA2 is associated with adult and childhood height in the general population.
3 Additional References
GP00000486
HMGA2
P52926
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
HMGA2
Homo sapiens
human - (species)
Published - Accepted by Curator
HMGA2
Ear size
Unknown,
Unknown
Sus scrofa domesticus
domestic pig - (subspecies)
Domesticated
Linkage Mapping
Li P; Xiao S; Wei N ; et al. (2012)
Fine mapping of a QTL for ear size on porcine chromosome 5 and identification of high mobility group[...]
GP00000487
HMGA2
P52926
Morphology
unknown
Sus scrofa
pig - (species)
Sus scrofa domesticus
domestic pig - (subspecies)
HMGA2
Sus scrofa domesticus
domestic pig - (subspecies)
Published - Accepted by Curator
HSP90
Developmental time
Unknown,
Insertion
Locusta migratoria
migratory locust - (species) D
Intraspecific
Candidate Gene
Chen B; Zhang B; Xu L ; et al. (2017)
Transposable Element-Mediated Balancing Selection at Hsp90 Underlies Embryo Developmental Variation.
GP00002437
daf-21
Q18688
Physiology
an Lm1 SINE insertion in the third exon of the Hsp90 gene produces an alternative splicing form associated with faster development and higher developmental synchrony. Found by scanning Lm1 insertions in natural locust populations.
Locusta migratoria
migratory locust - (species)
Locusta migratoria
migratory locust - (species) D
HSP90
Locusta migratoria
migratory locust - (species)
Published - Accepted by Curator
HTR2C serotonin receptor
Immune response (complement activation)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Association Mapping
Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010)
Across-line SNP association study of innate and adaptive immune response in laying hens.
GP00001595
HTR2C
F1N989
Physiology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
HTR2C serotonin receptor
Gallus gallus
chicken - (species)
Published - Accepted by Curator
HTR3A serotonin receptor
Immune response (antibody titre)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Association Mapping
Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010)
Across-line SNP association study of innate and adaptive immune response in laying hens.
GP00001596
HTR3A
A0A1D5P8L2
Physiology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
HTR3A serotonin receptor
Gallus gallus
chicken - (species)
Published - Accepted by Curator
Hybrid male rescue
Hybrid incompatibility (F1 male lethality)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Brideau NJ; Flores HA; Wang J ; et al. (2006)
Two Dobzhansky-Muller genes interact to cause hybrid lethality in Drosophila.
GP00000495
Hmr
Q86CW5
Physiology
Rapid coding divergence
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
Hybrid male rescue
Drosophila simulans
(species)
Published - Accepted by Curator
I cluster
Pathogen resistance
Unknown,
Unknown
Phaseolus vulgaris
(species) D
Domesticated
Linkage Mapping
Vallejos CE; Astua-Monge G; Jones V ; et al. (2006)
Genetic and molecular characterization of the I locus of Phaseolus vulgaris.
GP00000496
U5YMY7
Physiology
unknown; maps to a cluster of R-proteins
Phaseolus vulgaris
(species)
Phaseolus vulgaris
(species) D
I cluster
Phaseolus vulgaris
(species)
Published - Accepted by Curator
I Kappa B Kinase Interacting Protein (IKBIP)
Lifespan
Unknown,
Unknown
Nothobranchius furzeri
turquoise killifish - (species)
Intraspecific
Association Mapping
Reichwald K; Petzold A; Koch P ; et al. (2015)
Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.
GP00001678
IKBIP
Q70UQ0
Physiology
Under positive selection; down regulated in aging skin
Nothobranchius furzeri
turquoise killifish - (species)
Nothobranchius furzeri
turquoise killifish - (species)
I Kappa B Kinase Interacting Protein (IKBIP)
Nothobranchius furzeri
turquoise killifish - (species)
Published - Accepted by Curator
IGK
Pathogen resistance
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001382
IGKV1-5
P01602
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
IGK
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
Inhibitor of DNA binding 3 (id3)
Lifespan
Unknown,
Unknown
Nothobranchius furzeri
turquoise killifish - (species) D
Intraspecific
Association Mapping
Reichwald K; Petzold A; Koch P ; et al. (2015)
Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.
GP00001676
ID3
Q02535
Physiology
Signature of selection for id3. upregulated during aging in brain and skin. A radical substitution of a non-polar by a charged aa (A>Q) followed by a 2-aa deletion in the C-terminus
Nothobranchius furzeri
turquoise killifish - (species)
Nothobranchius furzeri
turquoise killifish - (species) D
Inhibitor of DNA binding 3 (id3)
Nothobranchius furzeri
turquoise killifish - (species)
Published - Accepted by Curator
InR
Fertility (ovariole number)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Green DA; Extavour CG (2012)
Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila[...]
1 Additional References
GP00000500
InR
P09208
Physiology
unknown; loss of function reduces ovariole number
Drosophila sechellia
(species)
Drosophila simulans
(species)
InR
Drosophila simulans
(species)
Published - Accepted by Curator
Insulin-like growth factor receptor 1 (IGF1R)
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000503
IGF1R
P08069
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
Insulin-like growth factor receptor 1 (IGF1R)
Homo sapiens
human - (species)
Published - Accepted by Curator
Interleukin 10 (IL10)
Immune response (antibody titre and complement activation)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Association Mapping
Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010)
Across-line SNP association study of innate and adaptive immune response in laying hens.
GP00001597
IL10
Q6A2H4
Physiology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
Interleukin 10 (IL10)
Gallus gallus
chicken - (species)
Published - Accepted by Curator
Interleukin 12B (IL12B)
Immune response (antibody titre)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Association Mapping
Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010)
Across-line SNP association study of innate and adaptive immune response in laying hens.
GP00001594
IL-12B
Q6X0K9
Physiology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
Interleukin 12B (IL12B)
Gallus gallus
chicken - (species)
Published - Accepted by Curator
Interleukin 17A (IL17A)
Immune response (antibody titre and complement activation)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Association Mapping
Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010)
Across-line SNP association study of innate and adaptive immune response in laying hens.
GP00001593
IL17A
B4ER12
Physiology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
Interleukin 17A (IL17A)
Gallus gallus
chicken - (species)
Published - Accepted by Curator
JAK2
Hematopoiesis (blood platelet count)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001613
JAK2
O60674
Physiology
G>A at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
JAK2
Homo sapiens
human - (species)
Published - Accepted by Curator
JAZF1
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Johansson A; Marroni F; Hayward C ; et al. (2009)
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide assoc[...]
1 Additional References
GP00000507
JAZF1
Q86VZ6
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
JAZF1
Homo sapiens
human - (species)
Published - Accepted by Curator
JMJD1C
Hematopoiesis (mean blood platelet volume)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001606
JMJD1C
Q15652
Physiology
T>A at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
JMJD1C
Homo sapiens
human - (species)
Published - Accepted by Curator
JYalpha
Hybrid incompatibility (F2 male sterility)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Masly JP; Jones CD; Noor MA ; et al. (2006)
Gene transposition as a cause of hybrid sterility in Drosophila.
GP00000508
JYalpha
A8QI34
Physiology
Gene transposition
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
JYalpha
Drosophila simulans
(species)
Published - Accepted by Curator
K+ uptake permease 9
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001430
POT9
O49423
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
K+ uptake permease 9
Arabidopsis arenosa
(species)
Published - Accepted by Curator
KCNH4 - uncertain
Freshwater adaptation
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species) D
Intraspecific
Association Mapping
Jones FC; Grabherr MG; Chan YF ; et al. (2012)
The genomic basis of adaptive evolution in threespine sticklebacks.
GP00000510
KCNH4
Q9UQ05
Physiology
Large Inversion resulting in alternative transcripts
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species) D
KCNH4 - uncertain
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
Kcnj13
Coloration
Unknown,
Unknown
Danio aesculapii
(species) D
Interspecific
Candidate Gene
Podobnik M; Frohnhöfer HG; Dooley CM ; et al. (2020)
Evolution of the potassium channel gene Kcnj13 underlies colour pattern diversification in Danio fis[...]
GP00002364
Kcnj13
P86046
Morphology
Danio rerio
zebrafish - (species)
Danio aesculapii
(species) D
Kcnj13
Danio aesculapii
(species)
Published - Accepted by Curator
KCNQ1
Body size (height)
Unknown,
Epigenetic Change
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Zoledziewska M; Sidore C; Chiang CWK ; et al. (2015)
Height-reducing variants and selection for short stature in Sardinia.
GP00000511
KCNQ1
P51787
Morphology
unknown causative change in an imprinted region - consistent with maternal inheritance detected by the association
Homo sapiens
human - (species)
Homo sapiens
human - (species)
KCNQ1
Homo sapiens
human - (species)
Published - Accepted by Curator
kin of irre (kire)
Xenobiotic resistance (methylmercury ; development)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Association Mapping
Montgomery SL; Vorojeikina D; Huang W ; et al. (2014)
Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myo[...]
GP00001398
kirre
Q9N9Y9
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
kin of irre (kire)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase)
Coloration (coat)
Unknown,
Unknown
Vulpes vulpes
red fox - (species) D
Domesticated
Association Mapping
Kukekova AV; Johnson JL; Kharlamova AV ; et al. (2016)
Georgian white coat color of red fox (Vulpes vulpes) maps to fox chromosome 2 in the region containi[...]
GP00001328
Kit
P05532
Morphology
unknown
Vulpes vulpes
red fox - (species)
Vulpes vulpes
red fox - (species) D
Kit (type III receptor protein-tyrosine kinase)
Vulpes vulpes
red fox - (species)
Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]
Coloration (coat)
Unknown,
Complex Change
Bos grunniens
domestic yak - (species) D
Domesticated
Candidate Gene
Zhang MQ; Xu X; Luo SJ (2014)
The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens).
GP00001343
Kit
P05532
Morphology
haplotype Swf (indels and SNP)
Bos grunniens
domestic yak - (species)
Bos grunniens
domestic yak - (species) D
Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]
Bos grunniens
domestic yak - (species)
Published - Accepted by Curator
LACCASE 8
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001436
LAC8
Q9LFD2
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
LACCASE 8
Arabidopsis arenosa
(species)
Published - Accepted by Curator
LCORL
Body size
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Linkage Mapping
Lindholm-Perry AK; Sexten AK; Kuehn LA ; et al. (2011)
Association, effects and validation of polymorphisms within the NCAPG - LCORL locus located on BTA6 [...]
GP00000535
LCORL
Q8N3X6
Morphology
Not identified
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
LCORL
Bos taurus
cattle - (species)
Published - Accepted by Curator
LCORL
Body size
Unknown,
Unknown
Equus caballus
horse - (species)
Domesticated
Linkage Mapping
Makvandi-Nejad S; Hoffman GE; Allen JJ ; et al. (2012)
Four loci explain 83% of size variation in the horse.
3 Additional References
GP00000536
LCORL
Q8N3X6
Morphology
Not identified
Equus caballus
horse - (species)
Equus caballus
horse - (species)
LCORL
Equus caballus
horse - (species)
Published - Accepted by Curator
LCORL
Body size
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Horikoshi M; Yaghootkar H; Mook-Kanamori DO ; et al. (2013)
New loci associated with birth weight identify genetic links between intrauterine growth[...]
GP00000537
LCORL
Q8N3X6
Morphology
Not identified
Homo sapiens
human - (species)
Homo sapiens
human - (species)
LCORL
Homo sapiens
human - (species)
Published - Accepted by Curator
LIN28B
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000548
LIN28B
Q6ZN17
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
LIN28B
Homo sapiens
human - (species)
Published - Accepted by Curator
lncRNA:Hsr omega
Temperature tolerance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Intraspecific
Linkage Mapping
McKechnie SW; Halford MM; McColl G ; et al. (1998)
Both allelic variation and expression of nuclear and cytoplasmic transcripts of Hsr-omega are closel[...]
1 Additional References
GP00001999
Physiology
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
lncRNA:Hsr omega
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
LY86
Body fat distribution (visceral/subcutaneous ratio)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001562
LY86
O95711
Physiology
A>T in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
LY86
Homo sapiens
human - (species)
Published - Accepted by Curator
LYPLAL1
Body fat distribution (visceral/subcutaneous ratio)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001561
LYPLAL1
Q5VWZ2
Physiology
T>C in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
LYPLAL1
Homo sapiens
human - (species)
Published - Accepted by Curator
Mac1
Virulence
Unknown,
Unknown
Cryptococcus neoformans
(species)
Intraspecific
Linkage Mapping
Lin X; Huang JC; Mitchell TG ; et al. (2006)
Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha all[...]
GP00000560
CGB_D8050W
E6R4R6
Physiology
unknown
Cryptococcus neoformans
(species)
Cryptococcus neoformans
(species)
Mac1
Cryptococcus neoformans
(species)
Published - Accepted by Curator
MAP4K4
Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)
Unknown,
Unknown
Plutella xylostella
diamondback moth - (species) D
Intraspecific
Linkage Mapping
Guo Z; Kang S; Chen D ; et al. (2015)
MAPK signaling pathway alters expression of midgut ALP and ABCC genes and causes resistance to Bacil[...]
GP00001673
MAP4K4
O95819
Physiology
MAP4K4 constitutively up-regulated leading to up-regulated PxABCC1 and down-regulated PxABCC2 and PxABCC3 and reduction of membrane-bound ALP (mALP) expression responsible for reduced Cry1Ac toxin binding to midgut proteins
Plutella xylostella
diamondback moth - (species)
Plutella xylostella
diamondback moth - (species) D
MAP4K4
Plutella xylostella
diamondback moth - (species)
Published - Accepted by Curator
MARVELD3
Pathogen resistance (Plasmodium; malaria parasite)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Timmann C; Thye T; Vens M ; et al. (2012)
Genome-wide association study indicates two novel resistance loci for severe malaria.
GP00000564
MARVELD3
Q96A59
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
MARVELD3
Homo sapiens
human - (species)
Published - Accepted by Curator
MATE1/ZmMATE1
Metal tolerance
Unknown,
Unknown
Zea mays
(species)
Domesticated
Candidate Gene
Maron LG; Piñeros MA; Guimarães CT ; et al. (2010)
Two functionally distinct members of the MATE (multi-drug and toxic compound extrusion) family of tr[...]
GP00000566
Physiology
unknown
Zea mays
(species)
Zea mays
(species)
MATE1/ZmMATE1
Zea mays
(species)
Published - Accepted by Curator
Melanophilin (MLPH)
Coloration (feathers)
Unknown,
Complex Change
Coturnix japonica
Japanese quail - (species)
Domesticated
Linkage Mapping
Minvielle F; Cecchi T; Passamonti P ; et al. (2009)
Plumage colour mutations and melanins in the feathers of the Japanese quail: a first comparison.
1 Additional References
GP00000650
Mlph
Q91V27
Morphology
Large deletions and rearrangement with pseudogenization of MLPH and loss of two other genes
Coturnix japonica
Japanese quail - (species)
Coturnix japonica
Japanese quail - (species)
Melanophilin (MLPH)
Coturnix japonica
Japanese quail - (species)
Published - Accepted by Curator
Mi1.2
Pathogen resistance (parasite)
Unknown,
Unknown
Solanum lycopersicum
tomato - (species)
Intraspecific
Linkage Mapping
Rossi M; Goggin FL; Milligan SB ; et al. (1998)
The nematode resistance gene Mi of tomato confers resistance against the potato aphid.
2 Additional References
GP00000655
Mi-1.2
O81137
Physiology
Not identified
Solanum peruvianum
(species)
Solanum lycopersicum
tomato - (species)
Mi1.2
Solanum lycopersicum
tomato - (species)
Published - Accepted by Curator
Microphtalmia-associated transcription factor
Coloration (coat)
Unknown,
Unknown
Bos taurus
cattle - (species) D
Domesticated
Linkage Mapping
Fontanesi L; Scotti E; Russo V (2012)
Haplotype variability in the bovine MITF gene and association with piebaldism in Holstein and Simmen[...]
2 Additional References
GP00000656
Mitf
Q08874
Morphology
unknown but association with intronic variant
Bos taurus
cattle - (species)
Bos taurus
cattle - (species) D
Microphtalmia-associated transcription factor
Bos taurus
cattle - (species)
Published - Accepted by Curator
Microphtalmia-associated transcription factor
Coloration (coat)
Unknown,
Unknown
Bos taurus
cattle - (species) D
Domesticated
Association Mapping
Hofstetter S; Seefried F; Häfliger IM ; et al. (2019)
A non-coding regulatory variant in the 5'-region of the MITF gene is associated with white-spotted c[...]
GP00002326
Mitf
Q08874
Morphology
unknown based SNP association
Bos taurus
cattle - (species)
Bos taurus
cattle - (species) D
Microphtalmia-associated transcription factor
Bos taurus
cattle - (species)
Published - Accepted by Curator
MSH4
Recombination rate (female)
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001665
MSH4
E1BK76
Physiology
On chromosome 3. Associated SNP located in the intron of the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
MSH4
Bos taurus
cattle - (species)
Published - Accepted by Curator
Mucin gene family
Salt tolerance
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001378
MUC1
P15941
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
Mucin gene family
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
Na/K ATPase
Salt tolerance
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001377
ATP1A1
P05023
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
Na/K ATPase
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
natriuretic peptide precursor type C (NPPC)
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Estrada K; Krawczak M; Schreiber S ; et al. (2009)
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide si[...]
GP00000719
Nppc
Q61839
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
natriuretic peptide precursor type C (NPPC)
Homo sapiens
human - (species)
Published - Accepted by Curator
natriuretic peptide receptor 3 (NPR3)
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Estrada K; Krawczak M; Schreiber S ; et al. (2009)
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide si[...]
1 Additional References
GP00000720
NPR3
Q8L746
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
natriuretic peptide receptor 3 (NPR3)
Homo sapiens
human - (species)
Published - Accepted by Curator
NCED4
Seed dormancy
Unknown,
Unknown
Lactuca sativa
(species) D
Domesticated
Linkage Mapping
Argyris J; Truco MJ; Ochoa O ; et al. (2011)
A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature [...]
1 Additional References
GP00000737
CCD4
O49675
Physiology
unknown
Lactuca serriola
(species)
Lactuca sativa
(species) D
NCED4
Lactuca sativa
(species)
Published - Accepted by Curator
NEK9
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001663
NEK9
F1MM88
Physiology
On chromosome 10. Associated SNP located 10 kb dowstream
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
NEK9
Bos taurus
cattle - (species)
Published - Accepted by Curator
NV10127-NV10128-NV10129 gene cluster
Pheromone production (isomeric/chirality divergence)
Unknown,
Unknown
Nasonia giraulti
(species)
Interspecific
Linkage Mapping
Niehuis O; Buellesbach J; Gibson JD ; et al. (2013)
Behavioural and genetic analyses of Nasonia shed light on the evolution of sex pheromones.
GP00000744
NV10127
L8BRU0
Physiology
Not identified. Gene conversion between the three paralogues in tandem
Nasonia vitripennis
jewel wasp - (species)
Nasonia giraulti
(species)
NV10127-NV10128-NV10129 gene cluster
Nasonia giraulti
(species)
Published - Accepted by Curator
Odysseus-site homeobox
Hybrid incompatibility (F1 male sterility)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Bayes JJ; Malik HS (2009)
Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species.
GP00000752
OdsH
Q9VX20
Physiology
Rapid coding divergence
Drosophila mauritiana
(species)
Drosophila simulans
(species)
Odysseus-site homeobox
Drosophila simulans
(species)
Published - Accepted by Curator
OPRM1
Coloration (skin)
Unknown,
Unknown
Homo sapiens
human - (species) D
Intraspecific
Association Mapping
Quillen EE; Bauchet M; Bigham AW ; et al. (2012)
OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and European[...]
GP00001536
OPRM1
P35372
Morphology
C>T associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species) D
OPRM1
Homo sapiens
human - (species)
Published - Accepted by Curator
PABPN1
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001660
PABPN1
Q28165
Physiology
On chromosome 10. Associated SNP located dowstream of PABPN1
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
PABPN1
Bos taurus
cattle - (species)
Published - Accepted by Curator
PAP2
Coloration (anthocyanin accumulation under high-light and low-temperature stress)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Ilk N; Ding J; Ihnatowicz A ; et al. (2015)
Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attrib[...]
GP00001231
MYB90
Q9ZTC3
Physiology
one SNP in the coding region and several in the putative promoter region
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
PAP2
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
pastrel
Pathogen resistance (viruses)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Association Mapping
Magwire MM; Fabian DK; Schweyen H ; et al. (2012)
Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving [...]
GP00000854
pst
Q8IQ82
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
pastrel
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Patched1 (Ptc1)
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00000855
ptch1
Q98864
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
Patched1 (Ptc1)
Homo sapiens
human - (species)
Published - Accepted by Curator
pax3b
Coloration (scales)
Unknown,
Unknown
Tropheops sp. 'red cheek'
(species)
Interspecific
Linkage Mapping
Albertson RC; Powder KE; Hu Y ; et al. (2014)
Genetic basis of continuous variation in the levels and modular inheritance of pigmentation in cichl[...]
GP00001419
pax3-b
Q0IH87
Morphology
unknown
Labeotropheus fuelleborni
blue mbuna - (species)
Tropheops sp. 'red cheek'
(species)
pax3b
Tropheops sp. 'red cheek'
(species)
Published - Accepted by Curator
pdm3
Coloration (female abdomen)
Unknown,
Unknown
Drosophila burlai
(species)
Intraspecific
Linkage Mapping
Yassin A; Delaney EK; Reddiex AJ ; et al. (2016)
The pdm3 Locus Is a Hotspot for Recurrent Evolution of Female-Limited Color Dimorphism in Drosophila[...]
GP00001402
pdm3
A0A0B4LEG2
Morphology
unknown
Drosophila burlai
(species)
Drosophila burlai
(species)
pdm3
Drosophila burlai
(species)
Published - Accepted by Curator
Period (per)
Diapause
Unknown,
Unknown
Pieris napi
(species)
Intraspecific
Association Mapping
Pruisscher P; Nylin S; Wheat CW ; et al. (2021)
A region of the sex chromosome associated with population differences in diapause induction contains[...]
1 Additional References
GP00002427
per
P07663
Physiology
Multiple amino acid differences. Presence of five fixed SNPs between the N and S populations (one intergenic, two intronic and two exonic nonsynonymous substitutions).
Pieris napi
(species)
Pieris napi
(species)
Period (per)
Pieris napi
(species)
Published - Accepted by Curator
PGRP-LC
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Sackton TB; Lazzaro BP; Clark AG (2010)
Genotype and gene expression associations with immune function in Drosophila.
GP00000861
PGRP-LC
Q9GNK5
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
PGRP-LC
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
PHGPx
Xenobiotic resistance (gemcitabine ; female fertility)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Association Mapping
King EG; Kislukhin G; Walters KN ; et al. (2014)
Using Drosophila melanogaster to identify chemotherapy toxicity genes.
GP00001405
PHGPx
Q8IRD4
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
PHGPx
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
phytoene synthase
Carotenoid content (seed)
Unknown,
Unknown
Zea mays
(species)
Domesticated
Linkage Mapping
Palaisa KA; Morgante M; Williams M ; et al. (2003)
Contrasting effects of selection on sequence diversity and linkage disequilibrium at two phytoene sy[...]
1 Additional References
GP00000875
PSY1
P49085
Physiology
Not identified
Zea mays
(species)
Zea mays
(species)
phytoene synthase
Zea mays
(species)
Published - Accepted by Curator
Pib
Pathogen resistance
Unknown,
Unknown
Oryza sativa
rice - (species)
Domesticated
Linkage Mapping
Wang ZX; Yano M; Yamanouchi U ; et al. (1999)
The Pib gene for rice blast resistance belongs to the nucleotide binding and leucine-rich repeat cla[...]
GP00000882
Pi-b
Q9SSY0
Physiology
unknown
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
Pib
Oryza sativa
rice - (species)
Published - Accepted by Curator
PigmR
Pathogen resistance (plant fungus pathogen)
Unknown,
Unknown
Oryza sativa
rice - (species)
Intraspecific
Linkage Mapping
Deng Y; Zhai K; Xie Z ; et al. (2017)
Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance.
GP00001592
Pigm_GM4.7
A0A1P8CYR1
Physiology
unknown
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
PigmR
Oryza sativa
rice - (species)
Published - Accepted by Curator
PIK3CG
Hematopoiesis (mean blood platelet volume)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001611
PIK3CG
P48736
Physiology
C>G at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
PIK3CG
Homo sapiens
human - (species)
Published - Accepted by Curator
PPAR-alpha
Hypoxia response
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Simonson TS; Yang Y; Huff CD ; et al. (2010)
Genetic evidence for high-altitude adaptation in Tibet.
1 Additional References
GP00000917
PPARA
Q07869
Physiology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
PPAR-alpha
Homo sapiens
human - (species)
Published - Accepted by Curator
PPAR-delta
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
N'Diaye A; Chen GK; Palmer CD ; et al. (2011)
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of[...]
1 Additional References
GP00000918
PPARD
Q03181
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
PPAR-delta
Homo sapiens
human - (species)
Published - Accepted by Curator
Prdm9
Hybrid incompatibility (F1 male sterility)
Recombination rate (use of recombination hotspots)
Unknown,
Unknown
Mus musculus
house mouse - (species)
Intraspecific
Linkage Mapping
Mihola O; Trachtulec Z; Vlcek C ; et al. (2009)
A mouse speciation gene encodes a meiotic histone H3 methyltransferase.
2 Additional References
GP00000922
Prdm9
Q96EQ9
Physiology
Physiology
possible dosage difference (number of gene copies) interacting with an allele that affects post-transcriptional stability
Mus musculus
house mouse - (species)
Mus musculus
house mouse - (species)
Prdm9
Mus musculus
house mouse - (species)
Published - Accepted by Curator
Prdm9
Recombination rate (use of recombination hotspots)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Candidate Gene
Berg IL; Neumann R; Sarbajna S ; et al. (2011)
Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots [...]
GP00000923
Prdm9
Q96EQ9
Physiology
Various haplotypes
Homo sapiens
human - (species)
Homo sapiens
human - (species)
Prdm9
Homo sapiens
human - (species)
Published - Accepted by Curator
PRKCD
Pathogen resistance
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001381
PRKCD
Q05655
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
PRKCD
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
PROG1
Plant architecture
Unknown,
Unknown
Oryza sativa
rice - (species)
Domesticated
Candidate Gene
Tan L; Li X; Liu F ; et al. (2008)
Control of a key transition from prostrate to erect growth in rice domestication.
2 Additional References
GP00000925
PROG1
Q69NY0
Morphology
Various
Oryza rufipogon
(species)
Oryza sativa
rice - (species)
PROG1
Oryza sativa
rice - (species)
Published - Accepted by Curator
prophenoloxidase 1 (PPO1)
Enzymatic activity
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Intraspecific
Candidate Gene
Asada N (1997)
Genetic variants affecting phenoloxidase activity in Drosophila melanogaster.
GP00002001
Physiology
Exact causing mutation(s) unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
prophenoloxidase 1 (PPO1)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
PRR37-like Photoperiod-H1 (Ppd-H1)
Flowering time
Unknown,
Unknown
Hordeum vulgare
(species)
Domesticated
Linkage Mapping
Turner A; Beales J; Faure S ; et al. (2005)
The pseudo-response regulator Ppd-H1 provides adaptation to photoperiod in barley.
1 Additional References
GP00000933
PRR37
Q0D3B6
Physiology
unknown
Hordeum vulgare
(species)
Hordeum vulgare
(species)
PRR37-like Photoperiod-H1 (Ppd-H1)
Hordeum vulgare
(species)
Published - Accepted by Curator
PSMD13
Hematopoiesis (mean blood platelet volume)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001615
PSMD13
Q9UNM6
Physiology
A>G at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
PSMD13
Homo sapiens
human - (species)
Published - Accepted by Curator
Pto
Pathogen resistance
Unknown,
Unknown
Solanum lycopersicum
tomato - (species)
Domesticated
Linkage Mapping
Martin GB; Brommonschenkel SH; Chunwongse J ; et al. (1993)
Map-based cloning of a protein kinase gene conferring disease resistance in tomato.
GP00000937
pto
P93215
Physiology
Not identified
Solanum lycopersicum
tomato - (species)
Solanum lycopersicum
tomato - (species)
Pto
Solanum lycopersicum
tomato - (species)
Published - Accepted by Curator
PVX_084940
Xenobiotic resistance (multiresistance to antimalarial drugs)
Unknown,
Unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Intraspecific
Association Mapping
Pearson RD; Amato R; Auburn S ; et al. (2016)
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
GP00001487
PVX_084940
A5K0T0
Physiology
unknown
Plasmodium vivax
malaria parasite P. vivax - (species)
Plasmodium vivax
malaria parasite P. vivax - (species)
PVX_084940
Plasmodium vivax
malaria parasite P. vivax - (species)
Published - Accepted by Curator
r1 colored1
Coloration (seeds)
Unknown,
Insertion
Zea mays
(species) D
Domesticated
Linkage Mapping
Hanson MA; Gaut BS; Stec AO ; et al. (1996)
Evolution of anthocyanin biosynthesis in maize kernels: the role of regulatory and enzymatic loci.
1 Additional References
GP00000947
Z138B04_Z333J11.11
Q8S483
Morphology
insertion of transposable element Ac
Zea mays
(species)
Zea mays
(species) D
r1 colored1
Zea mays
(species)
Published - Accepted by Curator
R2R3 MYB transcription factor
Trichome density (leaf)
Unknown,
Unknown
Erythranthe guttata
spotted monkey flower - (species)
Domesticated
Linkage Mapping
Hendrick MF; Finseth FR; Mathiasson ME ; et al. (2016)
The genetics of extreme microgeographic adaptation: an integrated approach identifies a major gene u[...]
GP00001598
PELAN
A0A060IEP7
Morphology
Unknown ; candidate indel in first intron and a nonsynonymous substitution (glutamine>lysine) in the 3rd exon
Erythranthe guttata
spotted monkey flower - (species)
Erythranthe guttata
spotted monkey flower - (species)
R2R3 MYB transcription factor
Erythranthe guttata
spotted monkey flower - (species)
Published - Accepted by Curator
RB1
Body size (weight)
Body size (bone length)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Linkage Mapping
Zhang H; Liu SH; Zhang Q ; et al. (2011)
Fine-mapping of quantitative trait loci for body weight and bone traits and positional cloning of th[...]
GP00000957
Morphology
Morphology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
RB1
Gallus gallus
chicken - (species)
Published - Accepted by Curator
REC114
Recombination rate
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001661
REC114
Q7Z4M0
Physiology
On chromosome 10. Associated SNP located dowstream of the gene
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
REC114
Bos taurus
cattle - (species)
Published - Accepted by Curator
Regulator of G-protein signaling 2 (RGS2)
Anxiety
Unknown,
Unknown
Mus musculus
house mouse - (species)
Intraspecific
Linkage Mapping
Yalcin B; Willis-Owen SA; Fullerton J ; et al. (2004)
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mic[...]
GP00000967
Rgs2
O08849
Behavior
unknown
Mus musculus
house mouse - (species)
Mus musculus
house mouse - (species)
Regulator of G-protein signaling 2 (RGS2)
Mus musculus
house mouse - (species)
Published - Accepted by Curator
RnrS
Xenobiotic resistance (gemcitabine ; female fertility)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Association Mapping
King EG; Kislukhin G; Walters KN ; et al. (2014)
Using Drosophila melanogaster to identify chemotherapy toxicity genes.
GP00001404
RnrS
P48592
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
RnrS
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
ROSEA
Coloration (flowers)
Unknown,
Unknown
Antirrhinum majus
snapdragon - (species)
Intraspecific
Linkage Mapping
Whibley AC; Langlade NB; Andalo C ; et al. (2006)
Evolutionary paths underlying flower color variation in Antirrhinum.
GP00000997
ROS1
Q2VAZ7
Morphology
Not identified
Antirrhinum majus
snapdragon - (species)
Antirrhinum majus
snapdragon - (species)
ROSEA
Antirrhinum majus
snapdragon - (species)
Published - Accepted by Curator
Rp3 cluster
Pathogen resistance
Unknown,
Unknown
Zea mays
(species)
Domesticated
Linkage Mapping
Webb CA; Richter TE; Collins NC ; et al. (2002)
Genetic and molecular characterization of the maize rp3 rust resistance locus.
GP00000999
rp3-1
Q6PW75
Physiology
unknown
Zea mays
(species)
Zea mays
(species)
Rp3 cluster
Zea mays
(species)
Published - Accepted by Curator
RPP1
Hybrid incompatibility
Unknown,
Complex Change
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Alcázar R; von Reth M; Bautor J ; et al. (2014)
Analysis of a plant complex resistance gene locus underlying immune-related hybrid incompatibility a[...]
1 Additional References
GP00001281
RPP1
F4J339
Physiology
complex
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
RPP1
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
RPP1
Hybrid incompatibility
Unknown,
Complex Change
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Alcázar R; von Reth M; Bautor J ; et al. (2014)
Analysis of a plant complex resistance gene locus underlying immune-related hybrid incompatibility a[...]
1 Additional References
GP00001282
RPP1
F4J339
Physiology
complex
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
RPP1
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
RREB1
Body fat distribution (visceral)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001555
RREB1
Q92766
Physiology
C>G in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
RREB1
Homo sapiens
human - (species)
Published - Accepted by Curator
SaM + SaF
Hybrid incompatibility (F1 male sterility)
Unknown,
Unknown
Oryza sativa
rice - (species)
Domesticated
Linkage Mapping
Long Y; Zhao L; Niu B ; et al. (2008)
Hybrid male sterility in rice controlled by interaction between divergent alleles of two adjacent ge[...]
1 Additional References
GP00001022
SaF+
B6RRX2
Physiology
Intron structure + aa changes on two adjacent coding genes
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
SaM + SaF
Oryza sativa
rice - (species)
Published - Accepted by Curator
scabrous
Bristle number (abdomen)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Lai C; Lyman RF; Long AD ; et al. (1994)
Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Droso[...]
GP00001024
sca
P21520
Morphology
unknown; but different sites than for thorax association
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
scabrous
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
scabrous
Bristle number (thorax)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Lai C; Lyman RF; Long AD ; et al. (1994)
Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Droso[...]
GP00001025
sca
P21520
Morphology
unknown; but different sites than for abdomen association
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
scabrous
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
sdY
Sex determination
Unknown,
Unknown
Teleostei
teleost fishes - (infraclass)
Interspecific
Linkage Mapping
Yano A; Guyomard R; Nicol B ; et al. (2012)
An immune-related gene evolved into the master sex-determining gene in rainbow trout, Oncorhynchus m[...]
GP00001033
sdy
I7GVT3
Physiology
Novel gene evolution by modification of the irf9 gene; unrelated to sex determination
Oncorhynchus mykiss
rainbow trout - (species)
Teleostei
teleost fishes - (infraclass)
sdY
Teleostei
teleost fishes - (infraclass)
Published - Accepted by Curator
Shattering1 - OsSh1
Seed shattering
Unknown,
Insertion
Oryza sativa
rice - (species) D
Domesticated
Association Mapping
Lin Z; Li X; Shannon LM ; et al. (2012)
Parallel domestication of the Shattering1 genes in cereals.
2 Additional References
GP00001039
YAB2
Q10FZ7
Physiology
>4kb insertion in intron (unclear)
Oryza sativa
rice - (species)
Oryza sativa
rice - (species) D
Shattering1 - OsSh1
Oryza sativa
rice - (species)
Published - Accepted by Curator
sid-2
Immune response (RNAi efficiency)
Unknown,
Unknown
Caenorhabditis elegans
(species)
Interspecific
Candidate Gene
Winston WM; Sutherlin M; Wright AJ ; et al. (2007)
Caenorhabditis elegans SID-2 is required for environmental RNA interference.
GP00001051
sid-2
G5EEV9
Physiology
unknown
Caenorhabditis
(genus)
Caenorhabditis elegans
(species)
sid-2
Caenorhabditis elegans
(species)
Published - Accepted by Curator
SMC3
Recombination rate (female)
Unknown,
Unknown
Bos taurus
cattle - (species)
Domesticated
Association Mapping
Ma L; O'Connell JR; VanRaden PM ; et al. (2015)
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.
GP00001666
SMC3
O97594
Physiology
On chromosome 26. Associated SNP located upstream
Bos taurus
cattle - (species)
Bos taurus
cattle - (species)
SMC3
Bos taurus
cattle - (species)
Published - Accepted by Curator
smooth
Bristle number (abdomen)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Intraspecific
Linkage Mapping
zur Lage P; Shrimpton AD; Flavell AJ ; et al. (1997)
Genetic and molecular analysis of smooth, a quantitative trait locus affecting bristle number in Dro[...]
GP00001996
Morphology
exact causing mutation(s) unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
smooth
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
SOD3
Oxidative stress resistance
Blood pressure
Unknown,
Unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Intraspecific
Association Mapping
Jones FC; Chan YF; Schmutz J ; et al. (2012)
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]
GP00001380
SOD3
P08294
Physiology
Physiology
unknown
Gasterosteus aculeatus
three-spined stickleback - (species)
Gasterosteus aculeatus
three-spined stickleback - (species)
SOD3
Gasterosteus aculeatus
three-spined stickleback - (species)
Published - Accepted by Curator
SR-CII
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Lazzaro BP; Sackton TB; Clark AG (2006)
Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.
GP00001071
Sr-CII
Q5ELW9
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
SR-CII
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
SRF3
Hybrid Incompatibility
Unknown,
Complex Change
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Alcázar R; García AV; Kronholm I ; et al. (2010)
Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between [...]
1 Additional References
GP00001072
SRF3
Q6R2K3
Physiology
Complex haplotype
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
SRF3
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
SRF3
Hybrid Incompatibility
Unknown,
Complex Change
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Alcázar R; García AV; Kronholm I ; et al. (2010)
Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between [...]
1 Additional References
GP00001073
SRF3
Q6R2K3
Physiology
Complex haplotype
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
SRF3
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
sulfate transporter 1;1
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001429
SULTR1;1
Q9SAY1
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
sulfate transporter 1;1
Arabidopsis arenosa
(species)
Published - Accepted by Curator
Tehao
Pathogen resistance
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Candidate Gene
Lazzaro BP; Sackton TB; Clark AG (2006)
Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.
GP00001115
Tehao
Q9VJX9
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
Tehao
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
TLR6-TLR1-TLR10 cluster
Immune response
Unknown,
Complex Change
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Laayouni H; Oosting M; Luisi P ; et al. (2014)
Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-li[...]
1 Additional References
GP00001130
TLR1
Q15399
Physiology
Several Complex Haplotypes under positive selection - evidence on Adaptive Introgression from Neanderthal (2 haplotypes) and Denisova (1 haplotype)
Homo sapiens
human - (species)
Homo sapiens
human - (species)
TLR6-TLR1-TLR10 cluster
Homo sapiens
human - (species)
Published - Accepted by Curator
touch insensitive larva B (tilB)
Pupation site choice
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Pischedda A; Shahandeh MP; Turner TL (2020)
The Loci of Behavioral Evolution: Evidence That Fas2 and tilB Underlie Differences in Pupation Site [...]
GP00002344
tilB
Q9VR52
Behavior
Gene identified via deficiency mapping. Gene more highly expressed in D. melanogaster than in D. simulans. RNAi in D. melanogaster leads to pupae pupating closer to the food.
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
touch insensitive larva B (tilB)
Drosophila simulans
(species)
Published - Accepted by Curator
TRIB2
Body fat distribution (pericardial)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001559
TRIB2
Q92519
Physiology
A>G in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
TRIB2
Homo sapiens
human - (species)
Published - Accepted by Curator
Trichohyalin
Hair type (straight)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Medland SE; Nyholt DR; Painter JN ; et al. (2009)
Common variants in the trichohyalin gene are associated with straight hair in Europeans.
GP00001134
TCHH
Q07283
Morphology
Not identified
Homo sapiens
human - (species)
Homo sapiens
human - (species)
Trichohyalin
Homo sapiens
human - (species)
Published - Accepted by Curator
TRIP11 (=GMAP-210)
Body size (height)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Lettre G (2011)
Recent progress in the study of the genetics of height.
GP00001138
TRIP11
Q15643
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
TRIP11 (=GMAP-210)
Homo sapiens
human - (species)
Published - Accepted by Curator
two pore channel
Xenobiotic resistance (soil contamination; serpentine)
Unknown,
Unknown
Arabidopsis arenosa
(species) D
Intraspecific
Association Mapping
Arnold BJ; Lahner B; DaCosta JM ; et al. (2016)
Borrowed alleles and convergence in serpentine adaptation.
GP00001433
TPC1
Q94KI8
Physiology
unknown
Arabidopsis arenosa
(species)
Arabidopsis arenosa
(species) D
two pore channel
Arabidopsis arenosa
(species)
Published - Accepted by Curator
Tyramine receptor 3
Exploration decision
Unknown,
Unknown
Caenorhabditis elegans
(species)
Intraspecific
Linkage Mapping
Bendesky A; Tsunozaki M; Rockman MV ; et al. (2011)
Catecholamine receptor polymorphisms affect decision-making in C. elegans.
GP00001141
tyra-3
Q7JNP9
Behavior
Non-coding
Caenorhabditis elegans
(species)
Caenorhabditis elegans
(species)
Tyramine receptor 3
Caenorhabditis elegans
(species)
Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)
Coloration (eyes; hair; skin)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Frudakis T; Thomas M; Gaskin Z ; et al. (2003)
Sequences associated with human iris pigmentation.
1 Additional References
GP00001157
Tyrp1
P07147
Morphology
unknown
Homo sapiens
human - (species)
Homo sapiens
human - (species)
tyrosinase-related protein 1 (TYRP1)
Homo sapiens
human - (species)
Published - Accepted by Curator
UBE2E2
Body fat distribution (visceral/subcutaneous ratio)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Chu AY; Deng X; Fisher VA ; et al. (2017)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyt[...]
GP00001553
UBE2E2
Q96LR5
Physiology
T>C in associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
UBE2E2
Homo sapiens
human - (species)
Published - Accepted by Curator
Ubiquitin conjugating enzyme E2H (Ubc-E2H)
Pathogen resistance (Drosophila C virus & cricket paralysis virus)
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species) D
Experimental Evolution
Association Mapping
Martins NE; Faria VG; Nolte V ; et al. (2014)
Host adaptation to viruses relies on few genes with different cross-resistance properties.
GP00001480
UbcE2H
Q7JW03
Physiology
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species) D
Ubiquitin conjugating enzyme E2H (Ubc-E2H)
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
UDP-glycosyltransferase 89A2
Plant secondary metabolites (xylosides vs. glucosides ratio)
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Li X; Svedin E; Mo H ; et al. (2014)
Exploiting natural variation of secondary metabolism identifies a gene controlling the glycosylation[...]
GP00001278
UGT89A2
Q9LZD8
Physiology
unknown
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
UDP-glycosyltransferase 89A2
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
Vanaso / disc losts
Olfactory behavior
Unknown,
Unknown
Drosophila melanogaster
fruit fly - (species)
Intraspecific
Linkage Mapping
Fanara JJ; Robinson KO; Rollmann SM ; et al. (2002)
Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior.
GP00001164
dlt
Q8T626
Behavior
unknown
Drosophila melanogaster
fruit fly - (species)
Drosophila melanogaster
fruit fly - (species)
Vanaso / disc losts
Drosophila melanogaster
fruit fly - (species)
Published - Accepted by Curator
Vertnin (VRTN) [possibly a pseudo-replicate of other Pig entry]
Vertebrae number
Unknown,
Unknown
Sus scrofa domesticus
domestic pig - (subspecies)
Domesticated
Linkage Mapping
Ren DR; Ren J; Ruan GF ; et al. (2012)
Mapping and fine mapping of quantitative trait loci for the number of vertebrae in a White Duroc × C[...]
GP00001166
Vrtn
Q3SYK4
Morphology
unknown
Sus scrofa
pig - (species)
Sus scrofa domesticus
domestic pig - (subspecies)
Vertnin (VRTN) [possibly a pseudo-replicate of other Pig entry]
Sus scrofa domesticus
domestic pig - (subspecies)
Published - Accepted by Curator
VGLL3 (vestigial-like family member 3 gene )
Age of sexual maturity
Unknown,
Unknown
Salmo salar
Atlantic salmon - (species)
Intraspecific
Association Mapping
Barson NJ; Aykanat T; Hindar K ; et al. (2015)
Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon.
1 Additional References
GP00001167
VGLL3
A8MV65
Physiology
candidate amino-acid substitutions
Salmo salar
Atlantic salmon - (species)
Salmo salar
Atlantic salmon - (species)
VGLL3 (vestigial-like family member 3 gene )
Salmo salar
Atlantic salmon - (species)
Published - Accepted by Curator
VIN3
Flowering time
Unknown,
Unknown
Arabidopsis thaliana
thale cress - (species)
Intraspecific
Linkage Mapping
Ågren J; Oakley CG; Lundemo S ; et al. (2017)
Adaptive divergence in flowering time among natural populations of Arabidopsis thaliana: Estimates o[...]
GP00001538
VIN3
Q9FIE3
Physiology
4 nonsynonymous substitutions and a 3 bp deletion
Arabidopsis thaliana
thale cress - (species)
Arabidopsis thaliana
thale cress - (species)
VIN3
Arabidopsis thaliana
thale cress - (species)
Published - Accepted by Curator
VvMYBA1
Coloration (fruit)
Unknown,
Unknown
Vitis vinifera
wine grape - (species)
Domesticated
Linkage Mapping
Fournier-Level A; Le Cunff L; Gomez C ; et al. (2009)
Quantitative genetic bases of anthocyanin variation in grape (Vitis vinifera L. ssp. sativa) berry: [...]
GP00001193
VvmybA1
Q6L973
Morphology
Gret1 insertion polymorphism + R188S + Q213P
Vitis vinifera
wine grape - (species)
Vitis vinifera
wine grape - (species)
VvMYBA1
Vitis vinifera
wine grape - (species)
Published - Accepted by Curator
WDR66
Hematopoiesis (mean blood platelet volume)
Unknown,
Unknown
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017)
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]
GP00001604
WDR66
Q8TBY9
Physiology
A>G at the associated SNP
Homo sapiens
human - (species)
Homo sapiens
human - (species)
WDR66
Homo sapiens
human - (species)
Published - Accepted by Curator
Xa1
Pathogen resistance
Unknown,
Unknown
Oryza sativa
rice - (species)
Intraspecific
Linkage Mapping
Yoshimura S; Yamanouchi U; Katayose Y ; et al. (1998)
Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation.
GP00001216
XA1
A0A0H5AGW3
Physiology
unknown
Oryza sativa
rice - (species)
Oryza sativa
rice - (species)
Xa1
Oryza sativa
rice - (species)
Published - Accepted by Curator
Xmrk
Hybrid incompatibility (melanoma)
Unknown,
Unknown
Xiphophorus hellerii
green swordtail - (species)
Interspecific
Linkage Mapping
Adam D; Dimitrijevic N; Schartl M (1993)
Tumor suppression in Xiphophorus by an accidentally acquired promoter.
1 Additional References
GP00001219
xmrk
P13388
Physiology
Various
Xiphophorus maculatus
southern platyfish - (species)
Xiphophorus hellerii
green swordtail - (species)
Xmrk
Xiphophorus hellerii
green swordtail - (species)
Published - Accepted by Curator
yellow
Coloration (male-specific)
Unknown,
Unknown
Drosophila merina
(species)
Interspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001550
y
P09957
Morphology
unknown
Drosophila ercepeae
(species)
Drosophila merina
(species)
yellow
Drosophila merina
(species)
Published - Accepted by Curator
yellow
Coloration (male-specific)
Unknown,
Unknown
Drosophila bipectinata
(species)
Interspecific
Linkage Mapping
Signor SA; Liu Y; Rebeiz M ; et al. (2016)
Genetic Convergence in the Evolution of Male-Specific Color Patterns in Drosophila.
GP00001551
y
P09957
Morphology
unknown
Drosophila malerkotliana
(species)
Drosophila bipectinata
(species)
yellow
Drosophila bipectinata
(species)
Published - Accepted by Curator
Zygotic hybrid rescue
F1 lethality (female-limited)
Unknown,
Unknown
Drosophila simulans
(species)
Interspecific
Linkage Mapping
Ferree PM; Barbash DA (2009)
Species-specific heterochromatin prevents mitotic chromosome segregation to cause hybrid lethality i[...]
GP00001228
Physiology
Heterochromatin incompatibilitity
Drosophila melanogaster
fruit fly - (species)
Drosophila simulans
(species)
Zygotic hybrid rescue
Drosophila simulans
(species)
Published - Accepted by Curator