Gephebase

Gephebase Search Results

This Summary Table shows only the major fields for each entry. If you are interested in other fields (gene synonyms, GO terms, molecular details of the mutation, comments, etc.), please export the .csv file, which contains the complete data for each entry. Please click on a GepheID if you want to see all information regarding a particular entry.

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Your research retrieved 331 results.

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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
18-wheeler	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00000001	18w A1ZBR2	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	18-wheeler	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
ABC transporter pvmrp1	Xenobiotic resistance (multiresistance to antimalarial drugs)	Unknown, Unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Intraspecific	Association Mapping	Pearson RD; Amato R; Auburn S ; et al. (2016) Genomic analysis of local variation and recent evolution in Plasmodium vivax.	GP00001486	PVX_097025 A5KCN4	Physiology	unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Plasmodium vivax malaria parasite P. vivax - (species)	ABC transporter pvmrp1	Plasmodium vivax malaria parasite P. vivax - (species)	Published - Accepted by Curator
ABCB1	Plant size (dwarfism)	Unknown, Unknown	Cenchrus americanus (species)	Domesticated	Linkage Mapping	Parvathaneni RK; Jakkula V; Padi FK ; et al. (2013) Fine-mapping and identification of a candidate gene underlying the d2 dwarfing phenotype in pearl mi[...]	GP00000006	ABCB1 Q9ZR72	Morphology	unknown	Cenchrus americanus (species)	Cenchrus americanus (species)	ABCB1	Cenchrus americanus (species)	Published - Accepted by Curator
ABCB7	Iron metabolism	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001379	ABCB7 O75027	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	ABCB7	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
ABCC2	Xenobiotic resistance (insecticide; Bt Cry1Ac)	Unknown, Unknown	Trichoplusia ni cabbage looper - (species) D	Intraspecific	Linkage Mapping	Baxter SW; Badenes-Pérez FR; Morrison A ; et al. (2011) Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera.	GP00000014	ABCC2 A0A0E3ZDK3	Physiology	Not identified	Trichoplusia ni cabbage looper - (species)	Trichoplusia ni cabbage looper - (species) D	ABCC2	Trichoplusia ni cabbage looper - (species)	Published - Accepted by Curator
ABCG2	Milk yield	Unknown, Unknown	Ovis aries sheep - (species)	Domesticated	Candidate Gene	García-Fernández M; Gutiérrez-Gil B; Sánchez JP ; et al. (2011) The role of bovine causal genes underlying dairy traits in Spanish Churra sheep.	GP00000016	Abcg2 Q7TMS5	Physiology	unknown	Ovis aries sheep - (species)	Ovis aries sheep - (species)	ABCG2	Ovis aries sheep - (species)	Published - Accepted by Curator
ABO histo blood group glycosyltransferase	ABO antigen blood type	Unknown, Unknown	Pan troglodytes chimpanzee - (species)	Intraspecific	Candidate Gene	Kermarrec N; Roubinet F; Apoil PA ; et al. (1999) Comparison of allele O sequences of the human and non-human primate ABO system.	GP00000024	ABO P16442	Physiology	unknown	Pan troglodytes chimpanzee - (species)	Pan troglodytes chimpanzee - (species)	ABO histo blood group glycosyltransferase	Pan troglodytes chimpanzee - (species)	Published - Accepted by Curator
ACD6 = ACCELERATED CELL DEATH 6	Plant size Pathogen resistance (plant microbes) Herbivore resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Todesco M; Balasubramanian S; Hu TT ; et al. (2010) Natural allelic variation underlying a major fitness trade-off in Arabidopsis thaliana. 1 Additional References Atwell S; Huang YS; Vilhjálmsson BJ (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines.	GP00000025	ACD6 Q8LPS2	Physiology Physiology Physiology	Various	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	ACD6 = ACCELERATED CELL DEATH 6	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ADAMTS10	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000050	ADAMTS10 Q9H324	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	ADAMTS10	Homo sapiens human - (species)	Published - Accepted by Curator
AGAMOUS-LIKE 50	Leaf number (at flowering time)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Association Mapping	Seymour DK; Chae E; Grimm DG ; et al. (2016) Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids.	GP00001450	AGAMOUS-like 50 Q9XIE7	Morphology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AGAMOUS-LIKE 50	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Agouti (ASIP)	Coloration (coat)	Cis-regulatory, Unknown	Vermivora cyanoptera blue-winged warbler - (species)	Interspecific	Association Mapping	Toews DP; Taylor SA; Vallender R ; et al. (2016) Plumage Genes and Little Else Distinguish the Genomes of Hybridizing Warblers.	GP00001331	Asip Q03288	Morphology	unknown - the divergent region falls in the 5prime region that is directly upstream of the associated coding region	Vermivora chrysoptera Golden-winged warbler - (species)	Vermivora cyanoptera blue-winged warbler - (species)	Agouti (ASIP)	Vermivora cyanoptera blue-winged warbler - (species)	Published - Accepted by Curator
agrecan	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000072	ACAN P16112	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	agrecan	Homo sapiens human - (species)	Published - Accepted by Curator
ALX1	Beak size	Unknown, Unknown	Geospiza (genus) D	Interspecific	Association Mapping	Lamichhaney S; Berglund J; Almén MS ; et al. (2015) Evolution of Darwin's finches and their beaks revealed by genome sequencing. 1 Additional References Almén MS; Lamichhaney S; Berglund J (2016) Adaptive radiation of Darwin's finches revisited using whole genome sequencing.	GP00000081	Alx1 Q8C8B0	Morphology	240kb haplotype with complex variation	Geospiza (genus)	Geospiza (genus) D	ALX1	Geospiza (genus)	Published - Accepted by Curator
ammonium transporter 2;1	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001431	AMT2 Q9M6N7	Physiology	seven aa substitutions	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	ammonium transporter 2;1	Arabidopsis arenosa (species)	Published - Accepted by Curator
AMPD1 (=CG32626)	Drug resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Kislukhin G; King EG; Walters KN ; et al. (2013) The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.	GP00000083	AMPD1 P23109	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	AMPD1 (=CG32626)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
AMPD1 [clinical; candidate gene study; added for insights on fly-human parallelism]	Drug resistance	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Wessels JA; van der Kooij SM; le Cessie S ; et al. (2007) A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset[...]	GP00000084	AMPD1 P23109	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	AMPD1 [clinical; candidate gene study; added for insights on fly-human parallelism]	Homo sapiens human - (species)	Published - Accepted by Curator
an2-like (Stan2)	Coloration (tuber skin)	Cis-regulatory, Unknown	Solanum tuberosum potato - (species)	Domesticated	Linkage Mapping	Jung CS; Griffiths HM; De Jong DM ; et al. (2009) The potato developer (D) locus encodes an R2R3 MYB transcription factor that regulates expression of[...]	GP00000088	AN2 A4GRU8	Morphology	unknown	Solanum tuberosum potato - (species)	Solanum tuberosum potato - (species)	an2-like (Stan2)	Solanum tuberosum potato - (species)	Published - Accepted by Curator
APJ1	Xenobiotic resistance (alcohol, ethanol)	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Swinnen S; Schaerlaekens K; Pais T ; et al. (2012) Identification of novel causative genes determining the complex trait of high ethanol tolerance in y[...]	GP00000097	APJ1 P53940	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	APJ1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
APL1 cluster	Pathogen resistance (Plasmodium; malaria parasite)	Unknown, Unknown	Anopheles gambiae African malaria mosquito - (species) D	Intraspecific	Linkage Mapping	Riehle MM; Markianos K; Niaré O ; et al. (2006) Natural malaria infection in Anopheles gambiae is regulated by a single genomic control region. 1 Additional References Rottschaefer SM; Riehle MM; Coulibaly B (2011) Exceptional diversity, maintenance of polymorphism, and recent directional selection on the APL1 mal[...]	GP00000098	APL1A L7RQU1	Physiology	Not identified	Anopheles gambiae African malaria mosquito - (species)	Anopheles gambiae African malaria mosquito - (species) D	APL1 cluster	Anopheles gambiae African malaria mosquito - (species)	Published - Accepted by Curator
AT5G41740/AT5G41750	Hybrid incompatibility (auto-immune necrosis)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Bomblies K; Lempe J; Epple P ; et al. (2007) Autoimmune response as a mechanism for a Dobzhansky-Muller-type incompatibility syndrome in plants.	GP00000105	MUF8.2 F4JYI4	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AT5G41740/AT5G41750	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ATP2B4	Pathogen resistance (Plasmodium; malaria parasite)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Timmann C; Thye T; Vens M ; et al. (2012) Genome-wide association study indicates two novel resistance loci for severe malaria.	GP00000127	ATP2B4 P23634	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	ATP2B4	Homo sapiens human - (species)	Published - Accepted by Curator
avpr1a	Male sexual fidelity (monogamous regime)	Cis-regulatory, Unknown	Microtus ochrogaster prairie vole - (species)	Intraspecific	Candidate Gene	Okhovat M; Berrio A; Wallace G ; et al. (2015) Sexual fidelity trade-offs promote regulatory variation in the prairie vole brain. 1 Additional References Berrio A; Guerrero RF; Aglyamova GV (2018) Complex selection on a regulator of social cognition: Evidence of balancing selection, regulatory in[...]	GP00000129	Avpr1a Q62463	Behavior	unknown	Microtus ochrogaster prairie vole - (species)	Microtus ochrogaster prairie vole - (species)	avpr1a	Microtus ochrogaster prairie vole - (species)	Published - Accepted by Curator
bab1	Coloration (abdomen)	3 Mutations: Cis-regulatory Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Kopp A; Graze RM; Xu S ; et al. (2003) Quantitative trait loci responsible for variation in sexually dimorphic traits in Drosophila melanog[...] 1 Additional References Bickel RD; Kopp A; Nuzhdin SV (2011) Composite effects of polymorphisms near multiple regulatory elements create a major-effect QTL.	GP00000130	bab1 Q9W0K7	Morphology	3 mutations	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	bab1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
bab2	Fertility (ovariole number)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Green DA; Extavour CG (2012) Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila[...] 1 Additional References Bergland AO; Genissel A; Nuzhdin SV (2008) Quantitative trait loci affecting phenotypic plasticity and the allometric relationship of ovariole [...]	GP00000132	bab2 Q9W0K4	Physiology	unknown ; loss of function reduces ovariole number	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	bab2	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
BAK1	Hematopoiesis (blood platelet count)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001616	BAK1 Q16611	Physiology	A>G at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	BAK1	Homo sapiens human - (species)	Published - Accepted by Curator
Barren inflorescence2 (BIF2)	Plant architecture Inflorescence architecture	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Pressoir G; Brown PJ; Zhu W ; et al. (2009) Natural variation in maize architecture is mediated by allelic differences at the PINOID co-ortholog[...] 1 Additional References Buckler ES; Holland JB; Bradbury PJ (2009) The genetic architecture of maize flowering time.	GP00000135	bif2 A6MW92	Morphology Morphology	unknown	Zea mays (species)	Zea mays (species)	Barren inflorescence2 (BIF2)	Zea mays (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Carotenoid content (skin ; shanks)	Cis-regulatory, Unknown	Gallus sonneratii gray junglefowl - (species) D Gallus gallus chicken - (species) D	Interspecific	Linkage Mapping	Eriksson J; Larson G; Gunnarsson U ; et al. (2008) Identification of the yellow skin gene reveals a hybrid origin of the domestic chicken. 1 Additional References Fallahshahroudi A; Sorato E; Altimiras J (2019) The Domestic BCO2 Allele Buffers Low-Carotenoid Diets in Chickens: Possible Fitness Increase Through[...]	GP00000139	BCO2 Q9BYV7	Morphology; Physiology	Not identified	Gallus gallus chicken - (species)	Gallus sonneratii gray junglefowl - (species) D Gallus gallus chicken - (species) D	BCO2 = beta-carotene oxygenase 2	Gallus sonneratii gray junglefowl - (species) Gallus gallus chicken - (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Coloration (feather)	Unknown, Unknown	Setophaga petechia yellow warbler - (species) D	Interspecific	Association Mapping	Baiz MD; Wood AW; Brelsford A ; et al. (2021) Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setop[...]	GP00002387	BCO2 Q9BYV7	Morphology		Setophaga pensylvanica Chestnut-sided warbler - (species)	Setophaga petechia yellow warbler - (species) D	BCO2 = beta-carotene oxygenase 2	Setophaga petechia yellow warbler - (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Coloration (feather)	Unknown, Unknown	Setophaga citrina hooded warbler - (species) D	Interspecific	Association Mapping	Baiz MD; Wood AW; Brelsford A ; et al. (2021) Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setop[...]	GP00002388	BCO2 Q9BYV7	Morphology		Setophaga ruticilla (species)	Setophaga citrina hooded warbler - (species) D	BCO2 = beta-carotene oxygenase 2	Setophaga citrina hooded warbler - (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula yallundae (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...]	GP00001821	TUB2 P02557	Physiology	Phe200Tyr	Oculimacula yallundae (species)	Oculimacula yallundae (species) D	beta-tubulin	Oculimacula yallundae (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula acuformis (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...]	GP00001822	TUB2 P02557	Physiology	Phe200Tyr	Oculimacula acuformis (species)	Oculimacula acuformis (species) D	beta-tubulin	Oculimacula acuformis (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula acuformis (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001823	TUB2 P02557	Physiology	E198A	Oculimacula acuformis (species)	Oculimacula acuformis (species) D	beta-tubulin	Oculimacula acuformis (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula acuformis (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001824	TUB2 P02557	Physiology	E198G	Oculimacula acuformis (species)	Oculimacula acuformis (species) D	beta-tubulin	Oculimacula acuformis (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula acuformis (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001825	TUB2 P02557	Physiology	E198K	Oculimacula acuformis (species)	Oculimacula acuformis (species) D	beta-tubulin	Oculimacula acuformis (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula yallundae (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001826	TUB2 P02557	Physiology	E198A	Oculimacula yallundae (species)	Oculimacula yallundae (species) D	beta-tubulin	Oculimacula yallundae (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula yallundae (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001827	TUB2 P02557	Physiology	E198G	Oculimacula yallundae (species)	Oculimacula yallundae (species) D	beta-tubulin	Oculimacula yallundae (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula yallundae (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001828	TUB2 P02557	Physiology	E198Q	Oculimacula yallundae (species)	Oculimacula yallundae (species) D	beta-tubulin	Oculimacula yallundae (species)	Published - Accepted by Curator
beta-tubulin	Xenobiotic resistance (benzimidazole)	Coding, SNP	Oculimacula yallundae (species) D	Intraspecific	Candidate Gene	Albertini Catherine; Gredt Michel; Leroux Pierre (1999 ) Mutations of the β-tubulin gene associated with different phenotypes of benzimidazole resistance in [...] 1 Additional References Fujimura Makoto; Kamakura Takashi; Inoue Hirokazu (1992 ) Sensitivity of Neurospora crassa to benzimidazoles and N-phenylcarbamates: effect of amino acid subs[...]	GP00001829	TUB2 P02557	Physiology	L240F	Oculimacula yallundae (species)	Oculimacula yallundae (species) D	beta-tubulin	Oculimacula yallundae (species)	Published - Accepted by Curator
BHLHE41	Hypoxia response	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Huerta-Sánchez E; Degiorgio M; Pagani L ; et al. (2013) Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations.	GP00000144	BHLHE41 Q9C0J9	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	BHLHE41	Homo sapiens human - (species)	Published - Accepted by Curator
BMP4 (uncertain)	Cranio-facial morphology	Unknown, Unknown	Maylandia zebra zebra mbuna - (species)	Interspecific	Linkage Mapping	Albertson RC; Streelman JT; Kocher TD ; et al. (2005) Integration and evolution of the cichlid mandible: the molecular basis of alternate feeding strategi[...] 2 Additional References Albertson RC; Streelman JT; Kocher TD (2005) Integration and evolution of the cichlid mandible: the molecular basis of alternate feeding strategi[...] Albertson RC; Kocher TD (2006) Genetic and developmental basis of cichlid trophic diversity.	GP00000153	bmp4 O13107	Morphology	Not identified	Labeotropheus fuelleborni blue mbuna - (species)	Maylandia zebra zebra mbuna - (species)	BMP4 (uncertain)	Maylandia zebra zebra mbuna - (species)	Published - Accepted by Curator
BOLTING TIME CONTROL 1 (BvBTC1)	Flowering time	Cis-regulatory, Unknown	Beta vulgaris (species)	Domesticated	Linkage Mapping	Pin PA; Zhang W; Vogt SH ; et al. (2012) The role of a pseudo-response regulator gene in life cycle adaptation and domestication of beet.	GP00000155	BTC1 I3NN18	Physiology	unknown	Beta vulgaris (species)	Beta vulgaris (species)	BOLTING TIME CONTROL 1 (BvBTC1)	Beta vulgaris (species)	Published - Accepted by Curator
Brassinosteroid-deficient dwarf1 (brd1)	Plant size (height)	Unknown, Unknown	Zea mays (species)	Intraspecific	Linkage Mapping	Peiffer JA; Romay MC; Gore MA ; et al. (2014) The genetic architecture of maize height.	GP00001628	ZEAMMB73_Zm00001d033180 A0A1D6KWT1	Morphology	On chromosome 1 two C>T transitions reduce plant height in 18RIL families	Zea mays (species)	Zea mays (species)	Brassinosteroid-deficient dwarf1 (brd1)	Zea mays (species)	Published - Accepted by Curator
brittle endosperm2 (Bt2) = endosperm ADP-glucose pyrophosphorylase small subunit	Sweet and brittle seed	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Preiss J; Danner S; Summers PS ; et al. (1990) Molecular Characterization of the Brittle-2 Gene Effect on Maize Endosperm ADPglucose Pyrophosphoryl[...]	GP00000158	bt2 Q84J79	Physiology	Not identified	Zea mays (species)	Zea mays (species)	brittle endosperm2 (Bt2) = endosperm ADP-glucose pyrophosphorylase small subunit	Zea mays (species)	Published - Accepted by Curator
Brix9-2-5/LIN5 invertase	Fruit sugar content	Unknown, Unknown	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Fridman E; Carrari F; Liu YS ; et al. (2004) Zooming in on a quantitative trait for tomato yield using interspecific introgressions.	GP00000159	LIN5 P93199	Physiology	Not identified	Solanum pennellii (species)	Solanum lycopersicum tomato - (species) D	Brix9-2-5/LIN5 invertase	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
cadherin	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Deletion	Ostrinia furnacalis Asian corn borer - (species) D	Intraspecific	Candidate Gene	Jin T; Chang X; Gatehouse AM ; et al. (2014) Downregulation and mutation of a Cadherin gene associated with Cry1Ac resistance in the Asian Corn B[...] 1 Additional References Jurat-Fuentes JL; Heckel DG; Ferré J (2021) Mechanisms of Resistance to Insecticidal Proteins from Bacillus thuringiensis.	GP00002464	A0A1B0RHM4	Physiology	MPR-r2 has a 26-amino acid residue deletion in the TBR which results in reduced binding of Cry1Ac compared to the MPR from the susceptible strain.	Ostrinia furnacalis Asian corn borer - (species)	Ostrinia furnacalis Asian corn borer - (species) D	cadherin	Ostrinia furnacalis Asian corn borer - (species)	Published - Accepted by Curator
cadherin	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, SNP	Ostrinia furnacalis Asian corn borer - (species) D	Intraspecific	Candidate Gene	Jin T; Chang X; Gatehouse AM ; et al. (2014) Downregulation and mutation of a Cadherin gene associated with Cry1Ac resistance in the Asian Corn B[...] 1 Additional References Jurat-Fuentes JL; Heckel DG; Ferré J (2021) Mechanisms of Resistance to Insecticidal Proteins from Bacillus thuringiensis.	GP00002465	A0A1B0RHM4	Physiology	Thr1457Ser	Ostrinia furnacalis Asian corn borer - (species)	Ostrinia furnacalis Asian corn borer - (species) D	cadherin	Ostrinia furnacalis Asian corn borer - (species)	Published - Accepted by Curator
calmodulin binding hydrolase	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001438	Q9FHQ0	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	calmodulin binding hydrolase	Arabidopsis arenosa (species)	Published - Accepted by Curator
Camta3	Plant size (height)	Unknown, Unknown	Zea mays (species)	Intraspecific	Association Mapping	Peiffer JA; Romay MC; Gore MA ; et al. (2014) The genetic architecture of maize height.	GP00001629	CAMTA3 Q8GSA7	Morphology	C>T transition on chromosome 3	Zea mays (species)	Zea mays (species)	Camta3	Zea mays (species)	Published - Accepted by Curator
Casparian strip membrane domain protein 1	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001432	CASP1 Q9SIH4	Physiology	five aa sustitutions	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	Casparian strip membrane domain protein 1	Arabidopsis arenosa (species)	Published - Accepted by Curator
CBF gene cluster	Temperature tolerance (cold)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Gery C; Zuther E; Schulz E ; et al. (2011) Natural variation in the freezing tolerance of Arabidopsis thaliana: effects of RNAi-induced CBF dep[...]	GP00000174	B1NSN2	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	CBF gene cluster	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ccdc170	Coloration	Unknown, Unknown	Anolis sagrei Brown anole - (species)	Intraspecific	Association Mapping	Feiner N; Brun-Usan M; Andrade P ; et al. (2022) A single locus regulates a female-limited color pattern polymorphism in a reptile.	GP00002363	Ccdc170 D3YXL0	Morphology		Anolis sagrei Brown anole - (species)	Anolis sagrei Brown anole - (species)	ccdc170	Anolis sagrei Brown anole - (species)	Published - Accepted by Curator
CG8492	Pathogen resistance (Drosophila C virus & flock house virus)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species) D	Experimental Evolution	Association Mapping	Martins NE; Faria VG; Nolte V ; et al. (2014) Host adaptation to viruses relies on few genes with different cross-resistance properties.	GP00001481	Dmel\CG8492 Q9VSA5	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	CG8492	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
CHRNA3/5 nicotine receptor cluster	Aging Smoking behavior	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Joshi PK; Fischer K; Schraut KE ; et al. (2016) Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.	GP00000185	CHRNA3 P32297	Physiology Physiology	unknown; complex variation with SNP association signal	Homo sapiens human - (species)	Homo sapiens human - (species)	CHRNA3/5 nicotine receptor cluster	Homo sapiens human - (species)	Published - Accepted by Curator
CLH1	Xenobiotic resistance (fungicide: guazatine)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Association Mapping	Atanasov KE; Barboza-Barquero L; Tiburcio AF ; et al. (2016) Genome Wide Association Mapping for the Tolerance to the Polyamine Oxidase Inhibitor Guazatine in Ar[...]	GP00001234	CLH1 O22527	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	CLH1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
colored plant 1	Coloration (seed)	Cis-regulatory, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Radicella JP; Brown D; Tolar LA ; et al. (1992) Allelic diversity of the maize B regulatory gene: different leader and promoter sequences of two B a[...]	GP00000190	b1 W5S3Q3	Morphology	Not identified	Zea mays (species)	Zea mays (species)	colored plant 1	Zea mays (species)	Published - Accepted by Curator
CYCD5;1	Endoreduplication	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Sterken R; Kiekens R; Boruc J ; et al. (2012) Combined linkage and association mapping reveals CYCD5;1 as a quantitative trait gene for endoredupl[...]	GP00000196	CYCD5-1 Q2V3B2	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	CYCD5;1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Cyp28d1	Xenobiotic resistance (nicotine ; larval stage)	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Chakraborty M; VanKuren NW; Zhao R ; et al. (2018) Hidden genetic variation shapes the structure of functional elements in Drosophila. 2 Additional References Marriage TN; King EG; Long AD (2014) Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation inter-cr[...] Chakraborty M; Emerson JJ; Macdonald SJ (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.	GP00001407	Cyp28d1 Q9VMT5	Physiology	insertion of a partial 1.5kb Accord transposable element and a Cyp28d1 gene tandem duplication (CNV - 3754 bp) that may play complementary role in resistance levels	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Cyp28d1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Cyp28d1	Xenobiotic resistance (nicotine ; larval stage)	Coding, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.	GP00002113	Cyp28d1 Q9VMT5	Physiology	insertion of a FW element (4720 bp) into the coding region (exon) of the second copy of the Cyp28d1 (there is still another copy of the gene left due to a duplication). Associated with a decrease in Cyp28d2 gene expression and a decrease in nicotin resistance.	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Cyp28d1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Cyp28d1-Cyp28d2	Xenobiotic resistance (nicotine ; larval stage)	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.	GP00002112	Cyp28d1 Q9VMT5	Physiology	duplication of 6063 bp which includes genes Cyp28d1; Cyp28d2 and CG7742. Associated with increased expression of Cyp28d2 and increased resistance to nicotin	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Cyp28d1-Cyp28d2	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Cyp28d1-Cyp28d2	Xenobiotic resistance (nicotine ; larval stage)	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.	GP00002114	Cyp28d1 Q9VMT5	Physiology	duplication of a 15297-bp region; which encompasses 5 genes: Msp300 Cyp28d2 Cyp28d1 CG7742 and CG14034. Associated with increased expression of Cyp28d1 gene expression and increased nicotin resistance	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Cyp28d1-Cyp28d2	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
CYP2J19	Coloration (feathers)	Unknown, Unknown	Serinus canaria common canary - (species)	Interspecific	Linkage Mapping	Lopes RJ; Johnson JD; Toomey MB ; et al. (2016) Genetic Basis for Red Coloration in Birds.	GP00000201	CYP2J2 P51589	Morphology	unknown	Spinus cucullatus red siskin - (species)	Serinus canaria common canary - (species)	CYP2J19	Serinus canaria common canary - (species)	Published - Accepted by Curator
CYP6BG1	Xenobiotic resistance (insecticide)	Cis-regulatory, Unknown	Plutella xylostella diamondback moth - (species) D	Intraspecific	Candidate Gene	Li X; Shan C; Li F ; et al. (2019) Transcription factor FTZ-F1 and cis-acting elements mediate expression of CYP6BG1 conferring resista[...] 1 Additional References Mallott M; Hamm S; Troczka BJ (2019) A flavin-dependent monooxgenase confers resistance to chlorantraniliprole in the diamondback moth, P[...]	GP00002064	CYP6BG1 A0A222NX20	Physiology	promoters tested in luciferase assays	Plutella xylostella diamondback moth - (species)	Plutella xylostella diamondback moth - (species) D	CYP6BG1	Plutella xylostella diamondback moth - (species)	Published - Accepted by Curator
CYP6P9 cluster (CYP6P9a and CYP6P9b)	Xenobiotic resistance (insecticide)	Cis-regulatory, Unknown	Anopheles funestus African malaria mosquito - (species) D	Intraspecific	Candidate Gene	Riveron JM; Irving H; Ndula M ; et al. (2013) Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in th[...] 1 Additional References Mugenzi LMJ; Menze BD; Tchouakui M (2019) Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy ag[...]	GP00000208	CYP2C9 P11712	Physiology	Cis-regulatory variation in CYP6P9b gene	Anopheles funestus African malaria mosquito - (species)	Anopheles funestus African malaria mosquito - (species) D	CYP6P9 cluster (CYP6P9a and CYP6P9b)	Anopheles funestus African malaria mosquito - (species)	Published - Accepted by Curator
CYP81F2	Glucosinolate content Herbivore resistance (aphids)	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Pfalz M; Vogel H; Kroymann J (2009) The gene controlling the indole glucosinolate modifier1 quantitative trait locus alters indole gluco[...]	GP00000212	CYP81F2 Q9LVD6	Physiology Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	CYP81F2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Darkener of apricot (Doa)	Lifespan	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	Hoedjes KM; Kostic H; Keller L ; et al. (2022) Natural alleles at the Doa locus underpin evolutionary changes in Drosophila lifespan and fecundity.	GP00002662	Doa P49762	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Darkener of apricot (Doa)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Dat	Coloration (puparium)	Unknown, Unknown	Drosophila virilis (species)	Interspecific	Linkage Mapping	Ahmed-Braimah YH; Sweigart AL (2015) A single gene causes an interspecific difference in pigmentation in Drosophila.	GP00001403	AANAT1 Q94521	Morphology	unknown	Drosophila americana (species)	Drosophila virilis (species)	Dat	Drosophila virilis (species)	Published - Accepted by Curator
DC-STAMP domain containing 2 (DCST2)	Body size	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	van der Valk RJ; Kreiner-Møller E; Kooijman MN ; et al. (2015) A novel common variant in DCST2 is associated with length in early life and height in adulthood.	GP00001509	DCST2 Q5T1A1	Morphology	SNP rs905938 C allele associated with an increase in birth length but probably not the causative mutation	Homo sapiens human - (species)	Homo sapiens human - (species)	DC-STAMP domain containing 2 (DCST2)	Homo sapiens human - (species)	Published - Accepted by Curator
Dca (=smp-30)	Wing size	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lee SF; Chen Y; Varan AK ; et al. (2011) Molecular basis of adaptive shift in body size in Drosophila melanogaster: functional and sequence a[...] 1 Additional References McKechnie SW; Blacket MJ; Song SV (2010) A clinally varying promoter polymorphism associated with adaptive variation in wing size in Drosophi[...]	GP00000214	smp-30 Q9VFG5	Morphology	Non-coding	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Dca (=smp-30)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Dihydrofolate reductase (pvdhfr)	Xenobiotic resistance (pyrimethamine)	Unknown, Unknown	Plasmodium vivax malaria parasite P. vivax - (species) D	Intraspecific	Association Mapping	Pearson RD; Amato R; Auburn S ; et al. (2016) Genomic analysis of local variation and recent evolution in Plasmodium vivax.	GP00001484	DHFR P00374	Physiology	unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Plasmodium vivax malaria parasite P. vivax - (species) D	Dihydrofolate reductase (pvdhfr)	Plasmodium vivax malaria parasite P. vivax - (species)	Published - Accepted by Curator
Dihydropteroate synthase (pvdhps)	Xenobiotic resistance (sulfadoxine)	Unknown, Unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Intraspecific	Association Mapping	Pearson RD; Amato R; Auburn S ; et al. (2016) Genomic analysis of local variation and recent evolution in Plasmodium vivax.	GP00001485	DHPS Q00LX9	Physiology	unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Plasmodium vivax malaria parasite P. vivax - (species)	Dihydropteroate synthase (pvdhps)	Plasmodium vivax malaria parasite P. vivax - (species)	Published - Accepted by Curator
Distal-less	Coloration (wing)	Cis-regulatory, Unknown	Bicyclus anynana squinting bush brown - (species)	Domesticated	Linkage Mapping	Beldade P; Brakefield PM; Long AD (2002) Contribution of Distal-less to quantitative variation in butterfly eyespots.	GP00000229	Dll P20009	Morphology	unknown	Bicyclus anynana squinting bush brown - (species)	Bicyclus anynana squinting bush brown - (species)	Distal-less	Bicyclus anynana squinting bush brown - (species)	Published - Accepted by Curator
Distorter on the X (Dox)	Sex determination (sex ratio distortion)	Coding, Deletion	Drosophila simulans (species) D	Intraspecific	Linkage Mapping	Tao Y; Araripe L; Kingan SB ; et al. (2007) A sex-ratio meiotic drive system in Drosophila simulans. II: an X-linked distorter.	GP00001969		Physiology	Deletion of 105bp, resulting in the loss of exon III, which deletes one of the 42bp elements that is tandemly repeated in wild-type Dsim\Dox.	Drosophila simulans (species)	Drosophila simulans (species) D	Distorter on the X (Dox)	Drosophila simulans (species)	Published - Accepted by Curator
Dopa-decarboxylase	Bristle number (abdomen)	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Mackay TF; Lyman RF (2005) Drosophila bristles and the nature of quantitative genetic variation.	GP00000232	Ddc P05031	Morphology	Promoter variation	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Dopa-decarboxylase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Dopa-decarboxylase	Lifespan	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	De Luca M; Roshina NV; Geiger-Thornsberry GL ; et al. (2003) Dopa decarboxylase (Ddc) affects variation in Drosophila longevity.	GP00000233	Ddc P05031	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Dopa-decarboxylase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Dopamine N-acetyltransferase (Dat)	Coloration (puparium)	Unknown, Unknown	Drosophila virilis (species) D	Interspecific	Linkage Mapping	Ahmed-Braimah YH; Sweigart AL (2015) A single gene causes an interspecific difference in pigmentation in Drosophila.	GP00000234	AANAT1 Q94521	Morphology	Not identified ; 11kb mapped interval including regulatory region and first exon	Drosophila americana (species)	Drosophila virilis (species) D	Dopamine N-acetyltransferase (Dat)	Drosophila virilis (species)	Published - Accepted by Curator
Doublesex (or neighbouring gene prospero)	Wing shape (sex-specific)	Cis-regulatory, Unknown	Nasonia giraulti (species)	Interspecific	Linkage Mapping	Loehlin DW; Oliveira DC; Edwards R ; et al. (2010) Non-coding changes cause sex-specific wing size differences between closely related species of Nason[...]	GP00000236	dsx P23023	Morphology	various	Nasonia vitripennis jewel wasp - (species)	Nasonia giraulti (species)	Doublesex (or neighbouring gene prospero)	Nasonia giraulti (species)	Published - Accepted by Curator
Drip	Fertility	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Bergland AO; Chae HS; Kim YJ ; et al. (2012) Fine-scale mapping of natural variation in fly fecundity identifies neuronal domain of expression an[...]	GP00000237	Drip Q9V5Z7	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Drip	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
ds1	Pathogen resistance	Unknown, Unknown	Sorghum bicolor sorghum - (species)	Domesticated	Linkage Mapping	Kawahigashi H; Kasuga S; Ando T ; et al. (2011) Positional cloning of ds1, the target leaf spot resistance gene against Bipolaris sorghicola in sorg[...]	GP00000238	ds1 K0IXC4	Physiology	unknown	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species)	ds1	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
DYM	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000242	DYM Q7RTS9	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	DYM	Homo sapiens human - (species)	Published - Accepted by Curator
EARLY FLOWERING 3/Hd17	Flowering time	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Matsubara K; Ogiso-Tanaka E; Hori K ; et al. (2012) Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flow[...]	GP00000247	ELF3 O82804	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	EARLY FLOWERING 3/Hd17	Oryza sativa rice - (species)	Published - Accepted by Curator
early responsive to dehydration stress protein 4	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001434	ERD4 Q9C8G5	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	early responsive to dehydration stress protein 4	Arabidopsis arenosa (species)	Published - Accepted by Curator
ebony	Coloration (abdomen)	Cis-regulatory, Unknown	Drosophila novamexicana (species) D	Intraspecific	Linkage Mapping	Wittkopp PJ; Stewart EE; Arnold LL ; et al. (2009) Intraspecific polymorphism to interspecific divergence: genetics of pigmentation in Drosophila. 1 Additional References Lamb Abigail M; Wang Zinan; Simmer Patricia (2020 ) ebony affects pigmentation divergence and cuticular hydrocarbons in Drosophila americana and D. nova[...]	GP00000248	e O76858	Morphology	Not identified	Drosophila americana (species)	Drosophila novamexicana (species) D	ebony	Drosophila novamexicana (species)	Published - Accepted by Curator
ebony	Coloration (thorax)	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Takahashi A; Takahashi K; Ueda R ; et al. (2007) Natural variation of ebony gene controlling thoracic pigmentation in Drosophila melanogaster. 1 Additional References Endler L; Gibert JM; Nolte V (2018) Pleiotropic effects of regulatory variation in tan result in correlation of two pigmentation traits [...]	GP00000249	e O76858	Morphology	Not identified	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	ebony	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Ectodysplasin (EDA)	Dermal bone (loss of armor plates)	Cis-regulatory, Unknown	Gasterosteus aculeatus three-spined stickleback - (species) D	Interspecific	Linkage Mapping	Colosimo PF; Hosemann KE; Balabhadra S ; et al. (2005) Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles. 2 Additional References Jones FC; Grabherr MG; Chan YF (2012) The genomic basis of adaptive evolution in threespine sticklebacks. O'Brown NM; Summers BR; Jones FC (2015) A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armo[...]	GP00000254	Eda O54693	Morphology	large haplotype- includes a T-> G regulatory change that affect expression based on differential responsiveness to Wnt signaling	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species) D	Ectodysplasin (EDA)	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
Ectodysplasin (EDA)	Scales (loss) Femoral glands (absent) Tooth number	Coding, Insertion	Pogona vitticeps central bearded dragon - (species) D	Intraspecific	Candidate Gene	Di-Poï N; Milinkovitch MC (2016) The anatomical placode in reptile scale morphogenesis indicates shared ancestry among skin appendage[...]	GP00002040	Eda O54693	Morphology Morphology Morphology	5′688–bp insertion of a transposon of the LTR-Gypsy family which generates a new splice donor site (gt) 42 bases upstream of the wild-type donor site; thus generating a 14–amino acid deletion in the corresponding transcript	Pogona vitticeps central bearded dragon - (species)	Pogona vitticeps central bearded dragon - (species) D	Ectodysplasin (EDA)	Pogona vitticeps central bearded dragon - (species)	Published - Accepted by Curator
EDN3	Coloration (coat) Coloration (eyes) Hearing (loss)	Unknown, Unknown	Lama glama llama - (species) D Vicugna pacos alpaca - (species) D	Domesticated	Candidate Gene	Fan R; Gu Z; Guang X ; et al. (2020) Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca.	GP00002182	EDN3 P14138	Morphology Morphology Physiology	Introgression from alpacas to lamas and clear correlation wit phenotype but no information on the mutation(s)	Vicugna vicugna vicugna - (species)	Lama glama llama - (species) D Vicugna pacos alpaca - (species) D	EDN3	Lama glama llama - (species) Vicugna pacos alpaca - (species)	Published - Accepted by Curator
EDN3	Coloration	Cis-regulatory, Unknown	Ambystoma mexicanum axolotl - (species) D	Domesticated	Candidate Gene	Woodcock MR; Vaughn-Wolfe J; Elias A ; et al. (2017) Identification of Mutant Genes and Introgressed Tiger Salamander DNA in the Laboratory Axolotl, Amby[...]	GP00002377	EDN3 P14138	Morphology		Ambystoma mexicanum axolotl - (species)	Ambystoma mexicanum axolotl - (species) D	EDN3	Ambystoma mexicanum axolotl - (species)	Published - Accepted by Curator
EGFR	Wing shape (length)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Dworkin I; Palsson A; Gibson G (2005) Replication of an Egfr-wing shape association in a wild-caught cohort of Drosophila melanogaster. 1 Additional References Palsson A; Dodgson J; Dworkin I (2005) Tests for the replication of an association between Egfr and natural variation in Drosophila melanog[...]	GP00000259	Egfr P04412	Morphology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	EGFR	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
EGFR	Coloration (skin)	Unknown, Unknown	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Quillen EE; Bauchet M; Bigham AW ; et al. (2012) OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and European[...]	GP00001537	EGFR P00533	Morphology	A>T associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species) D	EGFR	Homo sapiens human - (species)	Published - Accepted by Curator
egl-4 (Ppa-egl-4)	Insect pheromone attraction	Unknown, Unknown	Pristionchus pacificus (species)	Intraspecific	Association Mapping	Hong RL; Witte H; Sommer RJ (2008) Natural variation in Pristionchus pacificus insect pheromone attraction involves the protein kinase [...]	GP00000260	egl-4 O76360	Behavior	unknown	Pristionchus pacificus (species)	Pristionchus pacificus (species)	egl-4 (Ppa-egl-4)	Pristionchus pacificus (species)	Published - Accepted by Curator
EGLN1	Hypoxia response	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Bigham A; Bauchet M; Pinto D ; et al. (2010) Identifying signatures of natural selection in Tibetan and Andean populations using dense genome sca[...]	GP00000262	EGLN1 Q9GZT9	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	EGLN1	Homo sapiens human - (species)	Published - Accepted by Curator
EGLN1	High-altitude adaptation Hypoxia response	Unknown, Unknown	Anas flavirostris Yellow-billed teal - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002135	EGLN1 Q9GZT9	Physiology Physiology	probably cis-regulatory because no nonsynonymous mutations in the coding exon with high Fst	Anas flavirostris Yellow-billed teal - (species)	Anas flavirostris Yellow-billed teal - (species) D	EGLN1	Anas flavirostris Yellow-billed teal - (species)	Published - Accepted by Curator
EGLN1	High-altitude adaptation Hypoxia response	Unknown, Unknown	Anas georgica yellow-billed pintail - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002136	EGLN1 Q9GZT9	Physiology Physiology	probably cis-regulatory because no nonsynonymous mutations in the coding exon with high Fst	Anas georgica yellow-billed pintail - (species)	Anas georgica yellow-billed pintail - (species) D	EGLN1	Anas georgica yellow-billed pintail - (species)	Published - Accepted by Curator
EGNL1	High-altitude adaptation Hypoxia response	Cis-regulatory, Unknown	Anas cyanoptera cinnamon teal - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002134	EGLN1 Q9GZT9	Physiology Physiology	probably cis-regulatory because no nonsynonymous mutations in the coding exon with high Fst	Anas cyanoptera cinnamon teal - (species)	Anas cyanoptera cinnamon teal - (species) D	EGNL1	Anas cyanoptera cinnamon teal - (species)	Published - Accepted by Curator
EIF2AK3	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000264	EIF2AK3 Q9NZJ5	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	EIF2AK3	Homo sapiens human - (species)	Published - Accepted by Curator
EIF2S2	Coloration (skin)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Liu F; Visser M; Duffy DL ; et al. (2015) Genetics of skin color variation in Europeans: genome-wide association studies with functional follo[...]	GP00001359	EIF2S2 P20042	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	EIF2S2	Homo sapiens human - (species)	Published - Accepted by Curator
EPAS1	Hypoxia response	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Simonson TS; Yang Y; Huff CD ; et al. (2010) Genetic evidence for high-altitude adaptation in Tibet. 1 Additional References Xu S; Li S; Yang Y (2011) A genome-wide search for signals of high-altitude adaptation in Tibetans.	GP00000274	EPAS1 Q99814	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	EPAS1	Homo sapiens human - (species)	Published - Accepted by Curator
EPAS1	High-altitude adaptation Hypoxia response	Unknown, Unknown	Anas cyanoptera cinnamon teal - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002131	EPAS1 Q99814	Physiology Physiology	several candidate coding mutations	Anas cyanoptera cinnamon teal - (species)	Anas cyanoptera cinnamon teal - (species) D	EPAS1	Anas cyanoptera cinnamon teal - (species)	Published - Accepted by Curator
EPAS1	High-altitude adaptation Hypoxia response	Unknown, Unknown	Anas flavirostris Yellow-billed teal - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002132	EPAS1 Q99814	Physiology Physiology	several candidate coding mutations	Anas flavirostris Yellow-billed teal - (species)	Anas flavirostris Yellow-billed teal - (species) D	EPAS1	Anas flavirostris Yellow-billed teal - (species)	Published - Accepted by Curator
EPAS1	High-altitude adaptation Hypoxia response	Unknown, Unknown	Anas georgica yellow-billed pintail - (species) D	Intraspecific	Candidate Gene	Graham AM; McCracken KG (2019) Convergent evolution on the hypoxia-inducible factor (HIF) pathway genes EGLN1 and EPAS1 in high-alt[...]	GP00002133	EPAS1 Q99814	Physiology Physiology	several candidate coding mutations	Anas georgica yellow-billed pintail - (species)	Anas georgica yellow-billed pintail - (species) D	EPAS1	Anas georgica yellow-billed pintail - (species)	Published - Accepted by Curator
ephrin-a4	Coloration (scales)	Unknown, Unknown	Tropheops sp. 'red cheek' (species)	Interspecific	Linkage Mapping	Albertson RC; Powder KE; Hu Y ; et al. (2014) Genetic basis of continuous variation in the levels and modular inheritance of pigmentation in cichl[...]	GP00001420	EFNA4 P52798	Morphology	unknown	Labeotropheus fuelleborni blue mbuna - (species)	Tropheops sp. 'red cheek' (species)	ephrin-a4	Tropheops sp. 'red cheek' (species)	Published - Accepted by Curator
Epithiospecifier Modifier1 (ESM1)	Nitrile content	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Zhang Z; Ober JA; Kliebenstein DJ (2006) The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hy[...]	GP00000277	ESM1 Q9LJG3	Physiology	Not identified	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Epithiospecifier Modifier1 (ESM1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Epithiospecifier protein (ESP)	Plant secondary metabolite (glucosinolate) Herbivore resistance	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Lambrix V; Reichelt M; Mitchell-Olds T ; et al. (2001) The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and i[...]	GP00000278	ESP Q8RY71	Physiology Physiology	Not identified	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Epithiospecifier protein (ESP)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ERECTA	Plant architecture Leaf architecture Transpiration	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Masle J; Gilmore SR; Farquhar GD (2005) The ERECTA gene regulates plant transpiration efficiency in Arabidopsis. 2 Additional References El-Lithy ME; Reymond M; Stich B (2010) Relation among plant growth, carbohydrates and flowering time in the Arabidopsis Landsberg erecta x [...] Huang X; Paulo MJ; Boer M (2011) Analysis of natural allelic variation in Arabidopsis using a multiparent recombinant inbred line pop[...]	GP00000280	ERECTA Q42371	Morphology Morphology Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	ERECTA	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ERECTA	Pathogen resistance (Cucumerina fungus)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Llorente F; Alonso-Blanco C; Sánchez-Rodriguez C ; et al. (2005) ERECTA receptor-like kinase and heterotrimeric G protein from Arabidopsis are required for resistanc[...]	GP00001244	ERECTA Q42371	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	ERECTA	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ERG6	Xenobiotic resistance (drug)	Coding, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000288	erg6 O14321	Physiology	7 unique mutations in ERG6 within a total 19 lines ; 4 of these mutations evolved multiple times	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	ERG6	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
exp-1	Aggregation behavior	Cis-regulatory, Unknown	Caenorhabditis elegans (species)	Intraspecific	Linkage Mapping	Bendesky A; Pitts J; Rockman MV ; et al. (2012) Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus [...]	GP00000300	exp-1 G5ECJ0	Behavior	unidentified; 6.2kb wide genetic interval 3' of the exp-1 gene	Caenorhabditis elegans (species)	Caenorhabditis elegans (species)	exp-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
F2RL2	Hematopoiesis (mean blood platelet volume)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001617	F2RL2 O00254	Physiology	A>T at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	F2RL2	Homo sapiens human - (species)	Published - Accepted by Curator
FASCIATED EAR2	Grain yield (kernel row number)	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Bommert P; Nagasawa NS; Jackson D (2013) Quantitative variation in maize kernel row number is controlled by the FASCIATED EAR2 locus.	GP00000306	FEA2 Q940E8	Morphology	Not identified	Zea mays (species)	Zea mays (species)	FASCIATED EAR2	Zea mays (species)	Published - Accepted by Curator
Ferroportin 2	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001437	IREG2 F4KGN5	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	Ferroportin 2	Arabidopsis arenosa (species)	Published - Accepted by Curator
FGF4 retrogene	Limb size	Unknown, Insertion	Canis lupus familiaris dog - (subspecies) D	Domesticated	Association Mapping	Parker HG; VonHoldt BM; Quignon P ; et al. (2009) An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.	GP00000309	FGF4 J9P3I7	Morphology	Gene retroposition : 5kb insertion containing a FGF4 retrogene; 25Mb away from the complete (original) FGF4 gene	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	FGF4 retrogene	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
FGFR2	Hair thickness	Cis-regulatory, Unknown	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Fujimoto A; Nishida N; Kimura R ; et al. (2009) FGFR2 is associated with hair thickness in Asian populations.	GP00000314	FGFR2 P21802	Morphology	Unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	FGFR2	Homo sapiens human - (species)	Published - Accepted by Curator
fiz	Body size	3 Mutations: Cis-regulatory SNP	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Glaser-Schmitt A; Parsch J (2018) Functional characterization of adaptive variation within a cis-regulatory element influencing Drosop[...]	GP00002017	fiz Q9VY04	Morphology	3 mutations	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	fiz	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers)	Unknown, Unknown	Petunia x hybrida (species)	Domesticated	Candidate Gene	Brugliera F; Barri-Rewell G; Holton TA ; et al. (1999) Isolation and characterization of a flavonoid 3'-hydroxylase cDNA clone corresponding to the Ht1 loc[...]	GP00000320	CYP75B1 Q9SD85	Morphology	Not identified	Petunia x hybrida (species)	Petunia x hybrida (species)	flavonoid 3'-hydroxylase (F3'H)	Petunia x hybrida (species)	Published - Accepted by Curator
flavonoid 3';5'-hydroxylase (F3'5'H)	Coloration (flowers)	Cis-regulatory, Unknown	Phlox drummondii (species)	Intraspecific	Linkage Mapping	Hopkins R; Rausher MD (2011) Identification of two genes causing reinforcement in the Texas wildflower Phlox drummondii.	GP00000325	CYP75A2 P37120	Morphology	unknown	Phlox drummondii (species)	Phlox drummondii (species)	flavonoid 3';5'-hydroxylase (F3'5'H)	Phlox drummondii (species)	Published - Accepted by Curator
flavonoid 3';5'-hydroxylase (F3'5'H)	Coloration (tuber skin)	Cis-regulatory, Unknown	Solanum tuberosum potato - (species)	Domesticated	Linkage Mapping	Jung CS; Griffiths HM; De Jong DM ; et al. (2005) The potato P locus codes for flavonoid 3',5'-hydroxylase.	GP00000328	CYP75A2 P37120	Morphology	unknown	Solanum tuberosum potato - (species)	Solanum tuberosum potato - (species)	flavonoid 3';5'-hydroxylase (F3'5'H)	Solanum tuberosum potato - (species)	Published - Accepted by Curator
FLC (Flowering Locus C)	Flowering time	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Michaels SD; He Y; Scortecci KC ; et al. (2003) Attenuation of FLOWERING LOCUS C activity as a mechanism for the evolution of summer-annual flowerin[...] 1 Additional References Ågren J; Oakley CG; Lundemo S (2017) Adaptive divergence in flowering time among natural populations of Arabidopsis thaliana: Estimates o[...]	GP00000333	FLC Q9S7Q7	Physiology	Not identified	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	FLC (Flowering Locus C)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
FLC (Flowering Locus C)	Flowering time	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Werner JD; Borevitz JO; Uhlenhaut NH ; et al. (2005) FRIGIDA-independent variation in flowering time of natural Arabidopsis thaliana accessions. 1 Additional References Ågren J; Oakley CG; Lundemo S (2017) Adaptive divergence in flowering time among natural populations of Arabidopsis thaliana: Estimates o[...]	GP00000334	FLC Q9S7Q7	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	FLC (Flowering Locus C)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
FLC-2	Flowering time	Cis-regulatory, Unknown	Brassica rapa field mustard - (species)	Domesticated	Linkage Mapping	Zhao J; Kulkarni V; Liu N ; et al. (2010) BrFLC2 (FLOWERING LOCUS C) as a candidate gene for a vernalization response QTL in Brassica rapa.	GP00000340	FLC Q9S7Q7	Physiology	unknown	Brassica rapa field mustard - (species)	Brassica rapa field mustard - (species)	FLC-2	Brassica rapa field mustard - (species)	Published - Accepted by Curator
Flowering locus T (FT)	Flowering time	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Domesticated	Linkage Mapping	Kojima S; Takahashi Y; Kobayashi Y ; et al. (2002) Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1[...] 1 Additional References Schwartz C; Balasubramanian S; Warthmann N (2009) Cis-regulatory changes at FLOWERING LOCUS T mediate natural variation in flowering responses of Arab[...]	GP00000345	FT Q9SXZ2	Physiology	Promoter region	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Flowering locus T (FT)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Flowering locus T (LpFT3)	Flowering time	Cis-regulatory, Unknown	Lolium perenne (species)	Domesticated	Candidate Gene	Skøt L; Sanderson R; Thomas A ; et al. (2011) Allelic variation in the perennial ryegrass FLOWERING LOCUS T gene is associated with changes in flo[...]	GP00000347	FT Q9SXZ2	Physiology	unknown	Lolium perenne (species)	Lolium perenne (species)	Flowering locus T (LpFT3)	Lolium perenne (species)	Published - Accepted by Curator
Frigida (BnaA.FRI.a)	Flowering time	Unknown, Unknown	Brassica napus rape - (species)	Domesticated	Linkage Mapping	Wang N; Qian W; Suppanz I ; et al. (2011) Flowering time variation in oilseed rape (Brassica napus L.) is associated with allelic variation in[...]	GP00000356	FRI P0DH90	Physiology	unknown	Brassica napus rape - (species)	Brassica napus rape - (species)	Frigida (BnaA.FRI.a)	Brassica napus rape - (species)	Published - Accepted by Curator
FW2.2	Fruit size	Cis-regulatory, Unknown	Solanum lycopersicum tomato - (species)	Domesticated	Linkage Mapping	Frary A; Nesbitt TC; Grandillo S ; et al. (2000) fw2.2: a quantitative trait locus key to the evolution of tomato fruit size. 1 Additional References Nesbitt TC; Tanksley SD (2002) Comparative sequencing in the genus Lycopersicon. Implications for the evolution of fruit size in th[...]	GP00000383	ORFX Q9LKV7	Morphology	Not identified	Lycopersicon (subgenus)	Solanum lycopersicum tomato - (species)	FW2.2	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
G protein-coupled receptor rhodopsin	Diapause	Unknown, Unknown	Daphnia magna (species)	Intraspecific	Linkage Mapping	Roulin AC; Bourgeois Y; Stiefel U ; et al. (2016) A Photoreceptor Contributes to the Natural Variation of Diapause Induction in Daphnia magna.	GP00001539	RHO P08100	Physiology	unknown	Daphnia magna (species)	Daphnia magna (species)	G protein-coupled receptor rhodopsin	Daphnia magna (species)	Published - Accepted by Curator
GAL1	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001425	GAL1 P04385	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL10	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001428	GAL10 P04397	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL10	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL3	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001426	GAL3 P13045	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GAL4	Carbohydrate metabolism	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species) D	Interspecific	Candidate Gene	Roop JI; Chang KC; Brem RB (2016) Polygenic evolution of a sugar specialization trade-off in yeast.	GP00001427	GAL4 P04386	Physiology	unknown	Saccharomyces bayanus (species)	Saccharomyces cerevisiae baker's yeast - (species) D	GAL4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
GDF5	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Sanna S; Jackson AU; Nagaraja R ; et al. (2008) Common variants in the GDF5-UQCC region are associated with variation in human height. 1 Additional References Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000387	GDF5 P43026	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	GDF5	Homo sapiens human - (species)	Published - Accepted by Curator
gfzf	Hybrid incompatibility (F1 male lethality)	Unknown, Unknown	Drosophila simulans (species)	Interspecific	Linkage Mapping	Phadnis N; Baker EP; Cooper JC ; et al. (2015) An essential cell cycle regulation gene causes hybrid inviability in Drosophila.	GP00000392	gfzf Q6NP69	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila simulans (species)	gfzf	Drosophila simulans (species)	Published - Accepted by Curator
GH	Body size (dwarfism)	Coding, SNP	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	McCormack BL; Chase CC; Olson TA ; et al. (2009) A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the g[...]	GP00002037	GH1 P01241	Morphology	g.48768780C>T c.593C>T p.T198M	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	GH	Bos taurus cattle - (species)	Published - Accepted by Curator
Ghd7	Flowering time Inflorescence morphology	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Xue W; Xing Y; Weng X ; et al. (2008) Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice.	GP00000393	GHD7 E5RQA1	Physiology Morphology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Ghd7	Oryza sativa rice - (species)	Published - Accepted by Curator
GHSR	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000394	GHSR Q92847	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	GHSR	Homo sapiens human - (species)	Published - Accepted by Curator
GIBBERELLIC ACID REQUIRING 1 (GA1)	Flower morphology	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Brock MT; Kover PX; Weinig C (2012) Natural variation in GA1 associates with floral morphology in Arabidopsis thaliana.	GP00000395	GA1 Q38802	Morphology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	GIBBERELLIC ACID REQUIRING 1 (GA1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
GLABROUS1	Trichome (leaves)	Unknown, Unknown	Arabidopsis (genus)	Intraspecific	Candidate Gene	Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...] 1 Additional References Kivimäki M; Kärkkäinen K; Gaudeul M (2007) Gene, phenotype and function: GLABROUS1 and resistance to herbivory in natural populations of Arabid[...]	GP00000398	GL1 P27900	Morphology	unknown	Arabidopsis (genus)	Arabidopsis (genus)	GLABROUS1	Arabidopsis (genus)	Published - Accepted by Curator
Glycophorin GYPA-GYPB-GYPE cluster	Pathogen resistance (Plasmodium; malaria parasite)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	; Band G; Rockett KA ; et al. (2015) A novel locus of resistance to severe malaria in a region of ancient balancing selection.	GP00000406	GYPA P02724	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	Glycophorin GYPA-GYPB-GYPE cluster	Homo sapiens human - (species)	Published - Accepted by Curator
Glypican-3 (Gpc3)	Body size (weight)	Cis-regulatory, Unknown	Mus musculus house mouse - (species)	Domesticated	Linkage Mapping	Oliver F; Christians JK; Liu X ; et al. (2005) Regulatory variation at glypican-3 underlies a major growth QTL in mice.	GP00000407	Gpc3 Q8CFZ4	Physiology	unknown; possible 3'UTR variation	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Glypican-3 (Gpc3)	Mus musculus house mouse - (species)	Published - Accepted by Curator
GNBP1	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000408	GNBP1 Q9NHB0	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	GNBP1	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
GNBP2	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000409	GNBP2 Q9VVR4	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	GNBP2	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
GPR133	Body size (weight)	Cis-regulatory, Unknown	Mus musculus house mouse - (species)	Domesticated	Association Mapping	Chan YF; Jones FC; McConnell E ; et al. (2012) Parallel selection mapping using artificially selected mice reveals body weight control loci.	GP00000411	ADGRD1 Q6QNK2	Physiology	unknown	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	GPR133	Mus musculus house mouse - (species)	Published - Accepted by Curator
GPR133	Body size (height; male-limited)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Tönjes A; Koriath M; Schleinitz D ; et al. (2009) Genetic variation in GPR133 is associated with height: genome wide association study in the self-con[...]	GP00000412	ADGRD1 Q6QNK2	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	GPR133	Homo sapiens human - (species)	Published - Accepted by Curator
GRAIN INCOMPLETE FILLING 1	Grain weight	Cis-regulatory, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Wang E; Wang J; Zhu X ; et al. (2008) Control of rice grain-filling and yield by a gene with a potential signature of domestication.	GP00000413	CIN2 Q0JDC5	Morphology	unknown	Oryza rufipogon (species)	Oryza sativa rice - (species)	GRAIN INCOMPLETE FILLING 1	Oryza sativa rice - (species)	Published - Accepted by Curator
grassy tillers1	Plant architecture (number of ears)	Cis-regulatory, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Wills DM; Whipple CJ; Takuno S ; et al. (2013) From many, one: genetic control of prolificacy during maize domestication.	GP00000414	gt1 G1AQA5	Morphology	unknown but narrow 2.7kb interval	Zea mays (species)	Zea mays (species)	grassy tillers1	Zea mays (species)	Published - Accepted by Curator
GSS (glutathione synthetase)	Coloration (skin)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Liu F; Visser M; Duffy DL ; et al. (2015) Genetics of skin color variation in Europeans: genome-wide association studies with functional follo[...]	GP00001362	GSS P48637	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	GSS (glutathione synthetase)	Homo sapiens human - (species)	Published - Accepted by Curator
GSS (glutathione synthetase)	Xenobiotic resistance (arsenic)	Gene Amplification, Insertion	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Chakraborty M; Emerson JJ; Macdonald SJ ; et al. (2019) Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. 1 Additional References Ortiz JG; Opoka R; Kane D (2009) Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for[...]	GP00002115	Gss2 Q86B44	Physiology	tandem duplication creating the Gss1/Gss2 gene pair. Associated with increased expression of Gss1.	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	GSS (glutathione synthetase)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Anopheles funestus African malaria mosquito - (species)	Intraspecific	Candidate Gene	Riveron JM; Yunta C; Ibrahim SS ; et al. (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002455	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Anopheles funestus African malaria mosquito - (species)	Anopheles funestus African malaria mosquito - (species)	GSTe	Anopheles funestus African malaria mosquito - (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Spodoptera litura (species)	Intraspecific	Candidate Gene	Hilliou F; Chertemps T; Maïbèche M ; et al. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. 1 Additional References Riveron JM; Yunta C; Ibrahim SS (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002456	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Spodoptera litura (species)	Spodoptera litura (species)	GSTe	Spodoptera litura (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Spodoptera frugiperda fall armyworm - (species)	Intraspecific	Candidate Gene	Hilliou F; Chertemps T; Maïbèche M ; et al. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. 1 Additional References Riveron JM; Yunta C; Ibrahim SS (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002457	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Spodoptera frugiperda fall armyworm - (species)	Spodoptera frugiperda fall armyworm - (species)	GSTe	Spodoptera frugiperda fall armyworm - (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Spodoptera exigua beet armyworm - (species)	Intraspecific	Candidate Gene	Hilliou F; Chertemps T; Maïbèche M ; et al. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. 1 Additional References Riveron JM; Yunta C; Ibrahim SS (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002458	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Spodoptera exigua beet armyworm - (species)	Spodoptera exigua beet armyworm - (species)	GSTe	Spodoptera exigua beet armyworm - (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Spodoptera littoralis African cotton leafworm - (species)	Intraspecific	Candidate Gene	Hilliou F; Chertemps T; Maïbèche M ; et al. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. 1 Additional References Riveron JM; Yunta C; Ibrahim SS (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002459	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Spodoptera littoralis African cotton leafworm - (species)	Spodoptera littoralis African cotton leafworm - (species)	GSTe	Spodoptera littoralis African cotton leafworm - (species)	Published - Accepted by Curator
GSTe	Xenobiotic resistance (insecticide; DDT)	Coding, SNP	Anopheles funestus African malaria mosquito - (species)	Intraspecific	Candidate Gene	Hilliou F; Chertemps T; Maïbèche M ; et al. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. 1 Additional References Riveron JM; Yunta C; Ibrahim SS (2014) A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in[...]	GP00002460	GstE2 Q7JYZ9	Physiology	L119F. The resistant allele is more efficient at metabolizing DDT than the susceptible one.	Anopheles funestus African malaria mosquito - (species)	Anopheles funestus African malaria mosquito - (species)	GSTe	Anopheles funestus African malaria mosquito - (species)	Published - Accepted by Curator
GSTE1-E10 cluster	Xenobiotic resistance (drug)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Kislukhin G; King EG; Walters KN ; et al. (2013) The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.	GP00000419	GstE1 Q7KK90	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	GSTE1-E10 cluster	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
HAO1	Fertility (egg production) Bird head morphology (male comb)	Cis-regulatory, Unknown	Gallus gallus chicken - (species)	Domesticated	Linkage Mapping	Johnsson M; Gustafson I; Rubin CJ ; et al. (2012) A sexual ornament in chickens is affected by pleiotropic alleles at HAO1 and BMP2, selected during d[...] 1 Additional References Johnsson M; Rubin CJ; Höglund A (2014) The role of pleiotropy and linkage in genes affecting a sexual ornament and bone allocation in the c[...]	GP00000437	HAO1 E1BRR7	Physiology Morphology	unknown; but intergenic QTL peak with decomposed effects on expression of BMP2 and HAO1	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	HAO1	Gallus gallus chicken - (species)	Published - Accepted by Curator
HAS2	Wrinkled skin (Shar-Pei dogs)	Cis-regulatory, Unknown	Canis lupus familiaris dog - (subspecies) D	Domesticated	Association Mapping	Akey JM; Ruhe AL; Akey DT ; et al. (2010) Tracking footprints of artificial selection in the dog genome.	GP00000438	HAS2 J9PB16	Morphology	unknown	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	HAS2	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
HBS1L-MYB	Hematopoiesis (blood platelet count)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001614	HBS1L Q9Y450	Physiology	T>C at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	HBS1L-MYB	Homo sapiens human - (species)	Published - Accepted by Curator
heavy metal atpase4 (HMA4)	Metal tolerance	Unknown, Unknown	Arabidopsis halleri (species) D	Interspecific	Linkage Mapping	Courbot M; Willems G; Motte P ; et al. (2007) A major quantitative trait locus for cadmium tolerance in Arabidopsis halleri colocalizes with HMA4,[...]	GP00000447	HMA4 O64474	Physiology	unknown	Arabidopsis lyrata (species)	Arabidopsis halleri (species) D	heavy metal atpase4 (HMA4)	Arabidopsis halleri (species)	Published - Accepted by Curator
heavy metal atpase4 (HMA4)	Metal tolerance	Cis-regulatory, Unknown	Arabidopsis halleri (species)	Interspecific	Linkage Mapping	Hanikenne M; Talke IN; Haydon MJ ; et al. (2008) Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4. 1 Additional References Hanikenne M; Kroymann J; Trampczynska A (2013) Hard selective sweep and ectopic gene conversion in a gene cluster affording environmental adaptatio[...]	GP00000449	HMA4 O64474	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis halleri (species)	heavy metal atpase4 (HMA4)	Arabidopsis halleri (species)	Published - Accepted by Curator
high expression of osmotically responsive genes 2	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001435	SAL1 Q42546	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	high expression of osmotically responsive genes 2	Arabidopsis arenosa (species)	Published - Accepted by Curator
HLA-DQA1	Histocompatibility	Cis-regulatory, Unknown	Papio baboons - (genus)	Intraspecific	Candidate Gene	Loisel DA; Rockman MV; Wray GA ; et al. (2006) Ancient polymorphism and functional variation in the primate MHC-DQA1 5' cis-regulatory region.	GP00000478	HLA-DQA1 P01909	Physiology	Promoter variation	Papio baboons - (genus)	Papio baboons - (genus)	HLA-DQA1	Papio baboons - (genus)	Published - Accepted by Curator
HLA-DRB1	Pathogen resistance (typhoid fever)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Dunstan SJ; Hue NT; Han B ; et al. (2014) Variation at HLA-DRB1 is associated with resistance to enteric fever.	GP00000479	HLA-DRB1 Q30167	Physiology	uncharacterized	Homo sapiens human - (species)	Homo sapiens human - (species)	HLA-DRB1	Homo sapiens human - (species)	Published - Accepted by Curator
HM1 = HC toxin reductase (HCTR)	Pathogen resistance	Unknown, Unknown	Zea mays (species)	Domesticated	Candidate Gene	Multani DS; Meeley RB; Paterson AH ; et al. (1998) Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.	GP00000480	hm1 O49163	Physiology	Not identified	Zea mays (species)	Zea mays (species)	HM1 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
HMGA2	Body size	Unknown, Unknown	Canis lupus familiaris dog - (subspecies) D	Domesticated	Association Mapping	Akey JM; Ruhe AL; Akey DT ; et al. (2010) Tracking footprints of artificial selection in the dog genome. 1 Additional References Webster MT; Kamgari N; Perloski M (2015) Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds.	GP00000484	HMGA2 P52926	Morphology	unknown	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	HMGA2	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
HMGA2	Body size	Unknown, Unknown	Equus caballus horse - (species)	Domesticated	Association Mapping	Makvandi-Nejad S; Hoffman GE; Allen JJ ; et al. (2012) Four loci explain 83% of size variation in the horse.	GP00000485	HMGA2 P52926	Morphology	unknown	Equus caballus horse - (species)	Equus caballus horse - (species)	HMGA2	Equus caballus horse - (species)	Published - Accepted by Curator
HMGA2	Body size (height; bone mineral density)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Weedon MN; Lettre G; Freathy RM ; et al. (2007) A common variant of HMGA2 is associated with adult and childhood height in the general population. 3 Additional References Yang TL; Guo Y; Zhang LS (2010) HMGA2 is confirmed to be associated with human adult height. Kuipers A; Zhang Y; Cauley JA (2009) Association of a high mobility group gene (HMGA2) variant with bone mineral density. Horikoshi M; Yaghootkar H; Mook-Kanamori DO (2013) New loci associated with birth weight identify genetic links between intrauterine growth[...]	GP00000486	HMGA2 P52926	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	HMGA2	Homo sapiens human - (species)	Published - Accepted by Curator
HMGA2	Ear size	Unknown, Unknown	Sus scrofa domesticus domestic pig - (subspecies)	Domesticated	Linkage Mapping	Li P; Xiao S; Wei N ; et al. (2012) Fine mapping of a QTL for ear size on porcine chromosome 5 and identification of high mobility group[...]	GP00000487	HMGA2 P52926	Morphology	unknown	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies)	HMGA2	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
HOXC8 - uncertain	Feathers (crest morphology)	Cis-regulatory, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Wang Y; Gao Y; Imsland F ; et al. (2012) The crest phenotype in chicken is associated with ectopic expression of HOXC8 in cranial skin.	GP00000489	HOXC8 Q9YH13	Morphology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	HOXC8 - uncertain	Gallus gallus chicken - (species)	Published - Accepted by Curator
HTR2C serotonin receptor	Immune response (complement activation)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010) Across-line SNP association study of innate and adaptive immune response in laying hens.	GP00001595	HTR2C F1N989	Physiology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	HTR2C serotonin receptor	Gallus gallus chicken - (species)	Published - Accepted by Curator
HTR3A serotonin receptor	Immune response (antibody titre)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010) Across-line SNP association study of innate and adaptive immune response in laying hens.	GP00001596	HTR3A A0A1D5P8L2	Physiology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	HTR3A serotonin receptor	Gallus gallus chicken - (species)	Published - Accepted by Curator
I cluster	Pathogen resistance	Unknown, Unknown	Phaseolus vulgaris (species) D	Domesticated	Linkage Mapping	Vallejos CE; Astua-Monge G; Jones V ; et al. (2006) Genetic and molecular characterization of the I locus of Phaseolus vulgaris.	GP00000496	U5YMY7	Physiology	unknown; maps to a cluster of R-proteins	Phaseolus vulgaris (species)	Phaseolus vulgaris (species) D	I cluster	Phaseolus vulgaris (species)	Published - Accepted by Curator
IGK	Pathogen resistance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001382	IGKV1-5 P01602	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	IGK	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
Immune deficiency	Pathogen resistance	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sceurman BK; Clark AG (2004) Genetic basis of natural variation in D. melanogaster antibacterial immunity.	GP00000499	imd Q9NHG0	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Immune deficiency	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Inhibitor of DNA binding 3 (id3)	Lifespan	Unknown, Unknown	Nothobranchius furzeri turquoise killifish - (species) D	Intraspecific	Association Mapping	Reichwald K; Petzold A; Koch P ; et al. (2015) Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.	GP00001676	ID3 Q02535	Physiology	Signature of selection for id3. upregulated during aging in brain and skin. A radical substitution of a non-polar by a charged aa (A>Q) followed by a 2-aa deletion in the C-terminus	Nothobranchius furzeri turquoise killifish - (species)	Nothobranchius furzeri turquoise killifish - (species) D	Inhibitor of DNA binding 3 (id3)	Nothobranchius furzeri turquoise killifish - (species)	Published - Accepted by Curator
InR	Fertility (ovariole number)	Unknown, Unknown	Drosophila simulans (species)	Interspecific	Linkage Mapping	Green DA; Extavour CG (2012) Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila[...] 1 Additional References Orgogozo V; Broman KW; Stern DL (2006) High-resolution quantitative trait locus mapping reveals sign epistasis controlling ovariole number [...]	GP00000500	InR P09208	Physiology	unknown; loss of function reduces ovariole number	Drosophila sechellia (species)	Drosophila simulans (species)	InR	Drosophila simulans (species)	Published - Accepted by Curator
Insulin-like growth factor 1 (IGF1)	Body size	Cis-regulatory, Unknown	Canis lupus familiaris dog - (subspecies)	Domesticated	Association Mapping	Sutter NB; Bustamante CD; Chase K ; et al. (2007) A single IGF1 allele is a major determinant of small size in dogs. 1 Additional References Rimbault M; Beale HC; Schoenebeck JJ (2013) Derived variants at six genes explain nearly half of size reduction in dog breeds.	GP00000501	Igf1 P05017	Morphology	Not identified / several haplotypes	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies)	Insulin-like growth factor 1 (IGF1)	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
Insulin-like growth factor receptor 1 (IGF1R)	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000503	IGF1R P08069	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	Insulin-like growth factor receptor 1 (IGF1R)	Homo sapiens human - (species)	Published - Accepted by Curator
Interleukin 10 (IL10)	Immune response (antibody titre and complement activation)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010) Across-line SNP association study of innate and adaptive immune response in laying hens.	GP00001597	IL10 Q6A2H4	Physiology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	Interleukin 10 (IL10)	Gallus gallus chicken - (species)	Published - Accepted by Curator
Interleukin 12B (IL12B)	Immune response (antibody titre)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010) Across-line SNP association study of innate and adaptive immune response in laying hens.	GP00001594	IL-12B Q6X0K9	Physiology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	Interleukin 12B (IL12B)	Gallus gallus chicken - (species)	Published - Accepted by Curator
Interleukin 17A (IL17A)	Immune response (antibody titre and complement activation)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Association Mapping	Biscarini F; Bovenhuis H; van Arendonk JA ; et al. (2010) Across-line SNP association study of innate and adaptive immune response in laying hens.	GP00001593	IL17A B4ER12	Physiology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	Interleukin 17A (IL17A)	Gallus gallus chicken - (species)	Published - Accepted by Curator
IRA2	Growth rate (environment-dependent)	Coding, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Smith EN; Kruglyak L (2008) Gene-environment interaction in yeast gene expression.	GP00000505	IRA2 P19158	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	IRA2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
JAK2	Hematopoiesis (blood platelet count)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001613	JAK2 O60674	Physiology	G>A at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	JAK2	Homo sapiens human - (species)	Published - Accepted by Curator
JAZF1	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Johansson A; Marroni F; Hayward C ; et al. (2009) Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide assoc[...] 1 Additional References Soranzo N; Rivadeneira F; Chinappen-Horsley U (2009) Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations wi[...]	GP00000507	JAZF1 Q86VZ6	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	JAZF1	Homo sapiens human - (species)	Published - Accepted by Curator
JMJD1C	Hematopoiesis (mean blood platelet volume)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001606	JMJD1C Q15652	Physiology	T>A at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	JMJD1C	Homo sapiens human - (species)	Published - Accepted by Curator
JYalpha	Hybrid incompatibility (F2 male sterility)	Unknown, Unknown	Drosophila simulans (species)	Interspecific	Linkage Mapping	Masly JP; Jones CD; Noor MA ; et al. (2006) Gene transposition as a cause of hybrid sterility in Drosophila.	GP00000508	JYalpha A8QI34	Physiology	Gene transposition	Drosophila melanogaster fruit fly - (species)	Drosophila simulans (species)	JYalpha	Drosophila simulans (species)	Published - Accepted by Curator
K+ uptake permease 9	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001430	POT9 O49423	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	K+ uptake permease 9	Arabidopsis arenosa (species)	Published - Accepted by Curator
KCNH4 - uncertain	Freshwater adaptation	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species) D	Intraspecific	Association Mapping	Jones FC; Grabherr MG; Chan YF ; et al. (2012) The genomic basis of adaptive evolution in threespine sticklebacks.	GP00000510	KCNH4 Q9UQ05	Physiology	Large Inversion resulting in alternative transcripts	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species) D	KCNH4 - uncertain	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
kin of irre (kire)	Xenobiotic resistance (methylmercury ; development)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	Montgomery SL; Vorojeikina D; Huang W ; et al. (2014) Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myo[...]	GP00001398	kirre Q9N9Y9	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	kin of irre (kire)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase)	Coloration (coat)	Unknown, Unknown	Vulpes vulpes red fox - (species) D	Domesticated	Association Mapping	Kukekova AV; Johnson JL; Kharlamova AV ; et al. (2016) Georgian white coat color of red fox (Vulpes vulpes) maps to fox chromosome 2 in the region containi[...]	GP00001328	Kit P05532	Morphology	unknown	Vulpes vulpes red fox - (species)	Vulpes vulpes red fox - (species) D	Kit (type III receptor protein-tyrosine kinase)	Vulpes vulpes red fox - (species)	Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]	Coloration (coat)	Gene Amplification, Complex Change	Bos grunniens domestic yak - (species) D	Domesticated	Candidate Gene	Zhang MQ; Xu X; Luo SJ (2014) The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens).	GP00001342	Kit P05532	Morphology	serial translocations Cs6 and Cs29	Bos grunniens domestic yak - (species)	Bos grunniens domestic yak - (species) D	Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]	Bos grunniens domestic yak - (species)	Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]	Coloration (coat)	Unknown, Complex Change	Bos grunniens domestic yak - (species) D	Domesticated	Candidate Gene	Zhang MQ; Xu X; Luo SJ (2014) The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens).	GP00001343	Kit P05532	Morphology	haplotype Swf (indels and SNP)	Bos grunniens domestic yak - (species)	Bos grunniens domestic yak - (species) D	Kit (type III receptor protein-tyrosine kinase) [pseudoreplicate with two Bos taurus KIT entries]	Bos grunniens domestic yak - (species)	Published - Accepted by Curator
Kit ligand	Coloration (coat)	Cis-regulatory, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Miller CT; Beleza S; Pollen AA ; et al. (2007) cis-Regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebac[...] 1 Additional References Sulem P; Gudbjartsson DF; Stacey SN (2007) Genetic determinants of hair, eye and skin pigmentation in Europeans.	GP00000522	KITLG P21583	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	Kit ligand	Homo sapiens human - (species)	Published - Accepted by Curator
Kit ligand	Coloration (gills; ventrum)	Cis-regulatory, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Linkage Mapping	Miller CT; Beleza S; Pollen AA ; et al. (2007) cis-Regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebac[...]	GP00000523	KITLG P21583	Morphology	Not identified	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	Kit ligand	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
KRT27	Hair type (curly)	Coding, SNP	Bos taurus cattle - (species) D	Domesticated	Association Mapping	Daetwyler HD; Capitan A; Pausch H ; et al. (2014) Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle.	GP00002026	KRT27 Q0P5J6	Morphology	g.41636961C>G c.276C>G p.Asn92Lys	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	KRT27	Bos taurus cattle - (species)	Published - Accepted by Curator
LACCASE 8	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001436	LAC8 Q9LFD2	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	LACCASE 8	Arabidopsis arenosa (species)	Published - Accepted by Curator
Latexin (Lxn)	Stem cell number (hematopoietic precursors)	Cis-regulatory, Unknown	Mus musculus house mouse - (species)	Intraspecific	Linkage Mapping	Liang Y; Jansen M; Aronow B ; et al. (2007) The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in[...]	GP00000534	Lxn P70202	Morphology	Not identified	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Latexin (Lxn)	Mus musculus house mouse - (species)	Published - Accepted by Curator
LCORL	Body size	Unknown, Unknown	Bos taurus cattle - (species)	Domesticated	Linkage Mapping	Lindholm-Perry AK; Sexten AK; Kuehn LA ; et al. (2011) Association, effects and validation of polymorphisms within the NCAPG - LCORL locus located on BTA6 [...]	GP00000535	LCORL Q8N3X6	Morphology	Not identified	Bos taurus cattle - (species)	Bos taurus cattle - (species)	LCORL	Bos taurus cattle - (species)	Published - Accepted by Curator
LCORL	Body size	Unknown, Unknown	Equus caballus horse - (species)	Domesticated	Linkage Mapping	Makvandi-Nejad S; Hoffman GE; Allen JJ ; et al. (2012) Four loci explain 83% of size variation in the horse. 3 Additional References Metzger J; Schrimpf R; Philipp U (2013) Expression levels of LCORL are associated with body size in horses. Tetens J; Widmann P; Kühn C (2013) A genome-wide association study indicates LCORL/NCAPG as a candidate locus for withers height in Ger[...] Signer-Hasler H; Flury C; Haase B (2012) A genome-wide association study reveals loci influencing height and other conformation traits in hor[...]	GP00000536	LCORL Q8N3X6	Morphology	Not identified	Equus caballus horse - (species)	Equus caballus horse - (species)	LCORL	Equus caballus horse - (species)	Published - Accepted by Curator
LCORL	Body size	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Horikoshi M; Yaghootkar H; Mook-Kanamori DO ; et al. (2013) New loci associated with birth weight identify genetic links between intrauterine growth[...]	GP00000537	LCORL Q8N3X6	Morphology	Not identified	Homo sapiens human - (species)	Homo sapiens human - (species)	LCORL	Homo sapiens human - (species)	Published - Accepted by Curator
LIN28B	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000548	LIN28B Q6ZN17	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	LIN28B	Homo sapiens human - (species)	Published - Accepted by Curator
Mac1	Virulence	Unknown, Unknown	Cryptococcus neoformans (species)	Intraspecific	Linkage Mapping	Lin X; Huang JC; Mitchell TG ; et al. (2006) Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha all[...]	GP00000560	CGB_D8050W E6R4R6	Physiology	unknown	Cryptococcus neoformans (species)	Cryptococcus neoformans (species)	Mac1	Cryptococcus neoformans (species)	Published - Accepted by Curator
MAM1	Glucosinolate content	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Kroymann J; Textor S; Tokuhisa JG ; et al. (2001) A gene controlling variation in Arabidopsis glucosinolate composition is part of the methionine chai[...] 3 Additional References Chan EK; Rowe HC; Kliebenstein DJ (2010) Understanding the evolution of defense metabolites in Arabidopsis thaliana using genome-wide associa[...] Chan EK; Rowe HC; Corwin JA (2011) Combining genome-wide association mapping and transcriptional networks to identify novel genes contr[...] Züst T; Heichinger C; Grossniklaus U (2012) Natural enemies drive geographic variation in plant defenses.	GP00000562	MAM1 Q9FG67	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	MAM1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
MaMyb2	Coloration (flowers)	Cis-regulatory, Unknown	Diplacus aurantiacus (species)	Intraspecific	Linkage Mapping	Streisfeld MA; Young WN; Sobel JM (2013) Divergent selection drives genetic differentiation in an R2R3-MYB transcription factor that contribu[...]	GP00000563	Myb2 M9QXG2	Morphology	unknown expression-phenotype co-vary	Diplacus aurantiacus (species)	Diplacus aurantiacus (species)	MaMyb2	Diplacus aurantiacus (species)	Published - Accepted by Curator
MARVELD3	Pathogen resistance (Plasmodium; malaria parasite)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Timmann C; Thye T; Vens M ; et al. (2012) Genome-wide association study indicates two novel resistance loci for severe malaria.	GP00000564	MARVELD3 Q96A59	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	MARVELD3	Homo sapiens human - (species)	Published - Accepted by Curator
MATE1/AltSB/SbMATE	Metal tolerance	Cis-regulatory, Unknown	Sorghum bicolor sorghum - (species)	Domesticated	Linkage Mapping	Magalhaes JV; Liu J; Guimarães CT ; et al. (2007) A gene in the multidrug and toxic compound extrusion (MATE) family confers aluminum tolerance in sor[...]	GP00000565		Physiology	unknown	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species)	MATE1/AltSB/SbMATE	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
MATE1/ZmMATE1	Metal tolerance	Unknown, Unknown	Zea mays (species)	Domesticated	Candidate Gene	Maron LG; Piñeros MA; Guimarães CT ; et al. (2010) Two functionally distinct members of the MATE (multi-drug and toxic compound extrusion) family of tr[...]	GP00000566		Physiology	unknown	Zea mays (species)	Zea mays (species)	MATE1/ZmMATE1	Zea mays (species)	Published - Accepted by Curator
MdMYB10	Coloration (fruit flesh; foliage)	Cis-regulatory, Unknown	Malus domestica apple - (species)	Domesticated	Linkage Mapping	Chagné D; Carlisle CM; Blond C ; et al. (2007) Mapping a candidate gene (MdMYB10) for red flesh and foliage colour in apple. 1 Additional References Chagné D; Lin-Wang K; Espley RV (2013) An ancient duplication of apple MYB transcription factors is responsible for novel red fruit-flesh p[...]	GP00000639	MYB1 A0SQ35	Morphology	unknown	Malus domestica apple - (species)	Malus domestica apple - (species)	MdMYB10	Malus domestica apple - (species)	Published - Accepted by Curator
MdMYB110a	Coloration (fruit flesh)	Cis-regulatory, Unknown	Malus domestica apple - (species)	Domesticated	Linkage Mapping	Chagné D; Lin-Wang K; Espley RV ; et al. (2013) An ancient duplication of apple MYB transcription factors is responsible for novel red fruit-flesh p[...]	GP00000640	K4FA06	Morphology	unknown	Malus domestica apple - (species)	Malus domestica apple - (species)	MdMYB110a	Malus domestica apple - (species)	Published - Accepted by Curator
Melanophilin (MLPH)	Coloration (feathers)	Unknown, Complex Change	Coturnix japonica Japanese quail - (species)	Domesticated	Linkage Mapping	Minvielle F; Cecchi T; Passamonti P ; et al. (2009) Plumage colour mutations and melanins in the feathers of the Japanese quail: a first comparison. 1 Additional References Bed'hom B; Vaez M; Coville JL (2012) The lavender plumage colour in Japanese quail is associated with a complex mutation in the region of[...]	GP00000650	Mlph Q91V27	Morphology	Large deletions and rearrangement with pseudogenization of MLPH and loss of two other genes	Coturnix japonica Japanese quail - (species)	Coturnix japonica Japanese quail - (species)	Melanophilin (MLPH)	Coturnix japonica Japanese quail - (species)	Published - Accepted by Curator
MGAM	Starch processing	Cis-regulatory, Unknown	Canis lupus familiaris dog - (subspecies)	Domesticated	Association Mapping	Axelsson E; Ratnakumar A; Arendt ML ; et al. (2013) The genomic signature of dog domestication reveals adaptation to a starch-rich diet.	GP00000654	MGAM O43451	Physiology	unknown	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies)	MGAM	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
Mi1.2	Pathogen resistance (parasite)	Unknown, Unknown	Solanum lycopersicum tomato - (species)	Intraspecific	Linkage Mapping	Rossi M; Goggin FL; Milligan SB ; et al. (1998) The nematode resistance gene Mi of tomato confers resistance against the potato aphid. 2 Additional References Seah S; Yaghoobi J; Rossi M (2004) The nematode-resistance gene, Mi-1, is associated with an inverted chromosomal segment in susceptibl[...] Vos P; Simons G; Jesse T (1998) The tomato Mi-1 gene confers resistance to both root-knot nematodes and potato aphids.	GP00000655	Mi-1.2 O81137	Physiology	Not identified	Solanum peruvianum (species)	Solanum lycopersicum tomato - (species)	Mi1.2	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
Microphtalmia-associated transcription factor	Coloration (coat)	Unknown, Unknown	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Fontanesi L; Scotti E; Russo V (2012) Haplotype variability in the bovine MITF gene and association with piebaldism in Holstein and Simmen[...] 2 Additional References Hayes BJ; Pryce J; Chamberlain AJ (2010) Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat per[...] Jivanji S; Worth G; Lopdell TJ (2019) Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in c[...]	GP00000656	Mitf Q08874	Morphology	unknown but association with intronic variant	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Microphtalmia-associated transcription factor	Bos taurus cattle - (species)	Published - Accepted by Curator
Microphtalmia-associated transcription factor	Coloration (coat)	Unknown, Unknown	Bos taurus cattle - (species) D	Domesticated	Association Mapping	Hofstetter S; Seefried F; Häfliger IM ; et al. (2019) A non-coding regulatory variant in the 5'-region of the MITF gene is associated with white-spotted c[...]	GP00002326	Mitf Q08874	Morphology	unknown based SNP association	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Microphtalmia-associated transcription factor	Bos taurus cattle - (species)	Published - Accepted by Curator
mir-92a	Trichome pattern (leg)	Cis-regulatory, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Arif S; Murat S; Almudi I ; et al. (2013) Evolution of mir-92a underlies natural morphological variation in Drosophila melanogaster.	GP00000661		Morphology	Not identified	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	mir-92a	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Mla (=Sr33/AetRGA1e)	Pathogen resistance	Coding, Unknown	Aegilops tauschii (species)	Domesticated	Linkage Mapping	Periyannan S; Moore J; Ayliffe M ; et al. (2013) The gene Sr33, an ortholog of barley Mla genes, encodes resistance to wheat stem rust race Ug99.	GP00000667	Mla1 Q7EXP5	Physiology	Unknown	Triticum aestivum bread wheat - (species)	Aegilops tauschii (species)	Mla (=Sr33/AetRGA1e)	Aegilops tauschii (species)	Published - Accepted by Curator
Mucin gene family	Salt tolerance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001378	MUC1 P15941	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	Mucin gene family	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Cis-regulatory, SNP	Sus scrofa domesticus domestic pig - (subspecies)	Domesticated	Candidate Gene	Stinckens A; Luyten T; Bijttebier J ; et al. (2008) Characterization of the complete porcine MSTN gene and expression levels in pig breeds differing in [...]	GP00000696	MSTN O14793	Morphology	Possible promoter disruption ; changes the G nucleotide at position 8 of the MEF3 binding site into an A nucleotide, thus disrupting the MEF3 binding site	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies)	Myostatin (MSTN = GDF8)	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Racing performance	Cis-regulatory, Insertion	Equus caballus horse - (species) D	Domesticated	Candidate Gene	Binns MM; Boehler DA; Lambert DH (2010) Identification of the myostatin locus (MSTN) as having a major effect on optimum racing distance in [...] 3 Additional References Petersen JL; Mickelson JR; Rendahl AK (2013) Genome-wide analysis reveals selection for important traits in domestic horse breeds. Tozaki T; Hill EW; Hirota K (2012) A cohort study of racing performance in Japanese Thoroughbred racehorses using genome information on[...] Rooney MF; Hill EW; Kelly VP (2018) The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE i[...]	GP00000698	MSTN O14793	Morphology; Physiology	227-bp SINE insertion in promoter	Equus caballus horse - (species)	Equus caballus horse - (species) D	Myostatin (MSTN = GDF8)	Equus caballus horse - (species)	Published - Accepted by Curator
Na/K ATPase	Salt tolerance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001377	ATP1A1 P05023	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	Na/K ATPase	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
natriuretic peptide precursor type C (NPPC)	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Estrada K; Krawczak M; Schreiber S ; et al. (2009) A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide si[...]	GP00000719	Nppc Q61839	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	natriuretic peptide precursor type C (NPPC)	Homo sapiens human - (species)	Published - Accepted by Curator
natriuretic peptide receptor 3 (NPR3)	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Estrada K; Krawczak M; Schreiber S ; et al. (2009) A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide si[...] 1 Additional References Soranzo N; Rivadeneira F; Chinappen-Horsley U (2009) Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations wi[...]	GP00000720	NPR3 Q8L746	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	natriuretic peptide receptor 3 (NPR3)	Homo sapiens human - (species)	Published - Accepted by Curator
NCED4	Seed dormancy	Unknown, Unknown	Lactuca sativa (species) D	Domesticated	Linkage Mapping	Argyris J; Truco MJ; Ochoa O ; et al. (2011) A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature [...] 1 Additional References Huo H; Dahal P; Kunusoth K (2013) Expression of 9-cis-EPOXYCAROTENOID DIOXYGENASE4 is essential for thermoinhibition of lettuce seed g[...]	GP00000737	CCD4 O49675	Physiology	unknown	Lactuca serriola (species)	Lactuca sativa (species) D	NCED4	Lactuca sativa (species)	Published - Accepted by Curator
Not much yang (Nmy)	Sex determination (sex ratio distortion)	Coding, Deletion	Drosophila simulans (species) D	Intraspecific	Candidate Gene	Tao Y; Masly JP; Araripe L ; et al. (2007) A sex-ratio meiotic drive system in Drosophila simulans. I: an autosomal suppressor. 1 Additional References Tao Y; Araripe L; Kingan SB (2007) A sex-ratio meiotic drive system in Drosophila simulans. II: an X-linked distorter.	GP00001970		Physiology	Loss of one of the inverted repeats that is present in the wild-type Dsim\Nmy locus and loss of most of the sequence located between the inverted repeats (except for a 93bp element in reverse orientation).	Drosophila simulans (species)	Drosophila simulans (species) D	Not much yang (Nmy)	Drosophila simulans (species)	Published - Accepted by Curator
NUDT7	Meat color	Cis-regulatory, Unknown	Sus scrofa domesticus domestic pig - (subspecies)	Domesticated	Linkage Mapping	Taniguchi M; Hayashi T; Nii M ; et al. (2010) Fine mapping of quantitative trait loci for meat color on Sus scrofa chromosome 6: analysis of the s[...] 1 Additional References Taniguchi M; Hayashi T; Nii M (2010) Overexpression of NUDT7, a candidate quantitative trait locus for pork color, downregulates heme bio[...]	GP00000741	Nudt7 Q99P30	Physiology	unknown	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies)	NUDT7	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
NV10127-NV10128-NV10129 gene cluster	Pheromone production (isomeric/chirality divergence)	Unknown, Unknown	Nasonia giraulti (species)	Interspecific	Linkage Mapping	Niehuis O; Buellesbach J; Gibson JD ; et al. (2013) Behavioural and genetic analyses of Nasonia shed light on the evolution of sex pheromones.	GP00000744	NV10127 L8BRU0	Physiology	Not identified. Gene conversion between the three paralogues in tandem	Nasonia vitripennis jewel wasp - (species)	Nasonia giraulti (species)	NV10127-NV10128-NV10129 gene cluster	Nasonia giraulti (species)	Published - Accepted by Curator
ODORANT1 [pseudo-replication between 2 ODO1 entries due to possible homology between alleles]	Fragrance	Cis-regulatory, Unknown	Petunia exserta (species)	Interspecific	Linkage Mapping	Klahre U; Gurba A; Hermann K ; et al. (2011) Pollinator choice in Petunia depends on two major genetic Loci for floral scent production.	GP00000750	ODO1 Q50EX6	Physiology	Not identified; but probably homologous to P. hybrida Mitchell x R27 promoter variation since these P. hybrida accessions are derived from a P. axillaris x P. integrifolia cross	Petunia axillaris (species)	Petunia exserta (species)	ODORANT1 [pseudo-replication between 2 ODO1 entries due to possible homology between alleles]	Petunia exserta (species)	Published - Accepted by Curator
Odysseus-site homeobox	Hybrid incompatibility (F1 male sterility)	Unknown, Unknown	Drosophila simulans (species)	Interspecific	Linkage Mapping	Bayes JJ; Malik HS (2009) Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species.	GP00000752	OdsH Q9VX20	Physiology	Rapid coding divergence	Drosophila mauritiana (species)	Drosophila simulans (species)	Odysseus-site homeobox	Drosophila simulans (species)	Published - Accepted by Curator
OPRM1	Coloration (skin)	Unknown, Unknown	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Quillen EE; Bauchet M; Bigham AW ; et al. (2012) OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and European[...]	GP00001536	OPRM1 P35372	Morphology	C>T associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species) D	OPRM1	Homo sapiens human - (species)	Published - Accepted by Curator
Optix	Coloration (wing, Mullerian mimicry)	Cis-regulatory, Unknown	Heliconius pachinus (species)	Intraspecific	Linkage Mapping	Reed RD; Papa R; Martin A ; et al. (2011) optix drives the repeated convergent evolution of butterfly wing pattern mimicry. 1 Additional References Hines HM; Counterman BA; Papa R (2011) Wing patterning gene redefines the mimetic history of Heliconius butterflies.	GP00000795	Optix Q95RW8	Morphology	Not identified	Heliconius cydno (species)	Heliconius pachinus (species)	Optix	Heliconius pachinus (species)	Published - Accepted by Curator
Optix	Coloration (wing, Mullerian mimicry)	Cis-regulatory, Unknown	Heliconius himera (species)	Intraspecific	Linkage Mapping	Reed RD; Papa R; Martin A ; et al. (2011) optix drives the repeated convergent evolution of butterfly wing pattern mimicry. 1 Additional References Hines HM; Counterman BA; Papa R (2011) Wing patterning gene redefines the mimetic history of Heliconius butterflies.	GP00000796	Optix Q95RW8	Morphology	Not identified	Heliconius erato crimson-patched longwing - (species)	Heliconius himera (species)	Optix	Heliconius himera (species)	Published - Accepted by Curator
Optix	Coloration (wing, Mullerian mimicry)	Cis-regulatory, Unknown	Heliconius erato crimson-patched longwing - (species)	Intraspecific	Linkage Mapping	Reed RD; Papa R; Martin A ; et al. (2011) optix drives the repeated convergent evolution of butterfly wing pattern mimicry. 1 Additional References Hines HM; Counterman BA; Papa R (2011) Wing patterning gene redefines the mimetic history of Heliconius butterflies.	GP00000797	Optix Q95RW8	Morphology	Not identified	Heliconius erato crimson-patched longwing - (species)	Heliconius erato crimson-patched longwing - (species)	Optix	Heliconius erato crimson-patched longwing - (species)	Published - Accepted by Curator
Optix	Coloration (wing, Mullerian mimicry)	Cis-regulatory, Unknown	Heliconius melpomene postman butterfly - (species)	Intraspecific	Linkage Mapping	Reed RD; Papa R; Martin A ; et al. (2011) optix drives the repeated convergent evolution of butterfly wing pattern mimicry. 1 Additional References Hines HM; Counterman BA; Papa R (2011) Wing patterning gene redefines the mimetic history of Heliconius butterflies.	GP00000798	Optix Q95RW8	Morphology	Not identified	Heliconius melpomene postman butterfly - (species)	Heliconius melpomene postman butterfly - (species)	Optix	Heliconius melpomene postman butterfly - (species)	Published - Accepted by Curator
ORGANIC CATION TRANSPORTER 1	Root growth (root length response to exogenous cadaverine)	Cis-regulatory, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Strohm AK; Vaughn LM; Masson PH (2015) Natural variation in the expression of ORGANIC CATION TRANSPORTER 1 affects root length responses to[...]	GP00001279	OCT1 Q9CAT6	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	ORGANIC CATION TRANSPORTER 1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
OsCKX2=Gn1a	Grain yield	Cis-regulatory, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Ashikari M; Sakakibara H; Lin S ; et al. (2005) Cytokinin oxidase regulates rice grain production.	GP00000808	CKX2 Q4ADV8	Morphology	Not identified	Oryza sativa rice - (species)	Oryza sativa rice - (species)	OsCKX2=Gn1a	Oryza sativa rice - (species)	Published - Accepted by Curator
OsCKX2=Gn1a	Grain yield	Cis-regulatory, Unknown	Triticum aestivum bread wheat - (species)	Domesticated	Linkage Mapping	Zhang L; Zhao YL; Gao LF ; et al. (2012) TaCKX6-D1, the ortholog of rice OsCKX2, is associated with grain weight in hexaploid wheat.	GP00000809	CKX2 Q4ADV8	Morphology	unknown	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	OsCKX2=Gn1a	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
OsGA20ox1	Seedling vigor	Cis-regulatory, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Abe A; Takagi H; Fujibe T ; et al. (2012) OsGA20ox1, a candidate gene for a major QTL controlling seedling vigor in rice.	GP00000810	GA20OX1 P93771	Physiology	unknown ; no coding variation	Oryza sativa rice - (species)	Oryza sativa rice - (species)	OsGA20ox1	Oryza sativa rice - (species)	Published - Accepted by Curator
OsLG1	Seed shattering (panicle shape)	Cis-regulatory, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Ishii T; Numaguchi K; Miura K ; et al. (2013) OsLG1 regulates a closed panicle trait in domesticated rice.	GP00000811	SPL8 Q7XPY1	Morphology	unknown but fine-mapped 9.3kb region	Oryza rufipogon (species)	Oryza sativa rice - (species)	OsLG1	Oryza sativa rice - (species)	Published - Accepted by Curator
OsSPL16	Grain size Grain shape	Cis-regulatory, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Wang S; Wu K; Yuan Q ; et al. (2012) Control of grain size, shape and quality by OsSPL16 in rice. 1 Additional References Wang S; Li S; Liu Q (2015) The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and [...]	GP00000814	SPL16 L0AP48	Morphology Morphology	Promoter variation	Oryza sativa rice - (species)	Oryza sativa rice - (species)	OsSPL16	Oryza sativa rice - (species)	Published - Accepted by Curator
PAP2	Coloration (anthocyanin accumulation under high-light and low-temperature stress)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Ilk N; Ding J; Ihnatowicz A ; et al. (2015) Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attrib[...]	GP00001231	MYB90 Q9ZTC3	Physiology	one SNP in the coding region and several in the putative promoter region	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	PAP2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
pastrel	Pathogen resistance (viruses)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	Magwire MM; Fabian DK; Schweyen H ; et al. (2012) Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving [...]	GP00000854	pst Q8IQ82	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	pastrel	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Patched1 (Ptc1)	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00000855	ptch1 Q98864	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	Patched1 (Ptc1)	Homo sapiens human - (species)	Published - Accepted by Curator
Patched1 (Ptc1)	Cranio-facial morphology	Cis-regulatory, Unknown	Maylandia mbenjii (species) D	Interspecific	Linkage Mapping	Roberts RB; Hu Y; Albertson RC ; et al. (2011) Craniofacial divergence and ongoing adaptation via the hedgehog pathway. 1 Additional References Hu Y; Albertson RC (2014) Hedgehog signaling mediates adaptive variation in a dynamic functional system in the cichlid feeding[...]	GP00000856	ptch1 Q98864	Morphology	Uncharacterized cis-regulatory change - with ancestral Labeotropheus (LF) allele exhibiting relatively higher levels of expression	Labeotropheus fuelleborni blue mbuna - (species)	Maylandia mbenjii (species) D	Patched1 (Ptc1)	Maylandia mbenjii (species)	Published - Accepted by Curator
Pax7	Coloration (scales)	Cis-regulatory, Unknown	Maylandia zebra zebra mbuna - (species)	Interspecific	Linkage Mapping	Roberts RB; Ser JR; Kocher TD (2009) Sexual conflict resolved by invasion of a novel sex determiner in Lake Malawi cichlid fishes.	GP00000857	Pax7 P47239	Morphology	Not identified	Labeotropheus fuelleborni blue mbuna - (species)	Maylandia zebra zebra mbuna - (species)	Pax7	Maylandia zebra zebra mbuna - (species)	Published - Accepted by Curator
PGRP-LC	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Sackton TB; Lazzaro BP; Clark AG (2010) Genotype and gene expression associations with immune function in Drosophila.	GP00000861	PGRP-LC Q9GNK5	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	PGRP-LC	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
PHGPx	Xenobiotic resistance (gemcitabine ; female fertility)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	King EG; Kislukhin G; Walters KN ; et al. (2014) Using Drosophila melanogaster to identify chemotherapy toxicity genes.	GP00001405	PHGPx Q8IRD4	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	PHGPx	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
phytoene synthase	Carotenoid content (seed)	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Palaisa KA; Morgante M; Williams M ; et al. (2003) Contrasting effects of selection on sequence diversity and linkage disequilibrium at two phytoene sy[...] 1 Additional References Buckner B; Miguel PS; Janick-Buckner D (1996) The y1 gene of maize codes for phytoene synthase.	GP00000875	PSY1 P49085	Physiology	Not identified	Zea mays (species)	Zea mays (species)	phytoene synthase	Zea mays (species)	Published - Accepted by Curator
Pib	Pathogen resistance	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Wang ZX; Yano M; Yamanouchi U ; et al. (1999) The Pib gene for rice blast resistance belongs to the nucleotide binding and leucine-rich repeat cla[...]	GP00000882	Pi-b Q9SSY0	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Pib	Oryza sativa rice - (species)	Published - Accepted by Curator
PigmR	Pathogen resistance (plant fungus pathogen)	Unknown, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Deng Y; Zhai K; Xie Z ; et al. (2017) Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance.	GP00001592	Pigm_GM4.7 A0A1P8CYR1	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	PigmR	Oryza sativa rice - (species)	Published - Accepted by Curator
PIK3CG	Hematopoiesis (mean blood platelet volume)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001611	PIK3CG P48736	Physiology	C>G at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	PIK3CG	Homo sapiens human - (species)	Published - Accepted by Curator
Pl6	Pathogen resistance	Coding, Unknown	Helianthus annuus common sunflower - (species) D	Domesticated	Linkage Mapping	Franchel J; Bouzidi MF; Bronner G ; et al. (2013) Positional cloning of a candidate gene for resistance to the sunflower downy mildew, Plasmopara hals[...]	GP00000896	F8R6K4	Physiology	unknown ; cluster of several R-protein coding genes; of which only one is expressed	Helianthus annuus common sunflower - (species)	Helianthus annuus common sunflower - (species) D	Pl6	Helianthus annuus common sunflower - (species)	Published - Accepted by Curator
PPAR-alpha	Hypoxia response	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Simonson TS; Yang Y; Huff CD ; et al. (2010) Genetic evidence for high-altitude adaptation in Tibet. 1 Additional References Bigham A; Bauchet M; Pinto D (2010) Identifying signatures of natural selection in Tibetan and Andean populations using dense genome sca[...]	GP00000917	PPARA Q07869	Physiology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	PPAR-alpha	Homo sapiens human - (species)	Published - Accepted by Curator
PPAR-delta	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	N'Diaye A; Chen GK; Palmer CD ; et al. (2011) Identification, replication, and fine-mapping of Loci associated with adult height in individuals of[...] 1 Additional References Lango Allen H; Estrada K; Lettre G (2010) Hundreds of variants clustered in genomic loci and biological pathways affect human height.	GP00000918	PPARD Q03181	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	PPAR-delta	Homo sapiens human - (species)	Published - Accepted by Curator
Prdm9	Hybrid incompatibility (F1 male sterility) Recombination rate (use of recombination hotspots)	Unknown, Unknown	Mus musculus house mouse - (species)	Intraspecific	Linkage Mapping	Mihola O; Trachtulec Z; Vlcek C ; et al. (2009) A mouse speciation gene encodes a meiotic histone H3 methyltransferase. 2 Additional References Baudat F; Buard J; Grey C (2010) PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Flachs P; Mihola O; Simeček P (2012) Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility.	GP00000922	Prdm9 Q96EQ9	Physiology Physiology	possible dosage difference (number of gene copies) interacting with an allele that affects post-transcriptional stability	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Prdm9	Mus musculus house mouse - (species)	Published - Accepted by Curator
Prdm9	Recombination rate (use of recombination hotspots)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Berg IL; Neumann R; Sarbajna S ; et al. (2011) Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots [...]	GP00000923	Prdm9 Q96EQ9	Physiology	Various haplotypes	Homo sapiens human - (species)	Homo sapiens human - (species)	Prdm9	Homo sapiens human - (species)	Published - Accepted by Curator
PRKCD	Pathogen resistance	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001381	PRKCD Q05655	Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	PRKCD	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
PROG1	Plant architecture	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Candidate Gene	Tan L; Li X; Liu F ; et al. (2008) Control of a key transition from prostrate to erect growth in rice domestication. 2 Additional References Huang X; Kurata N; Wei X (2012) A map of rice genome variation reveals the origin of cultivated rice. Jin J; Huang W; Gao JP (2008) Genetic control of rice plant architecture under domestication.	GP00000925	PROG1 Q69NY0	Morphology	Various	Oryza rufipogon (species)	Oryza sativa rice - (species)	PROG1	Oryza sativa rice - (species)	Published - Accepted by Curator
Prolactin releasing hormone receptor (Prlhr/GPR10)	Body size (weight)	Cis-regulatory, Unknown	Mus musculus house mouse - (species)	Domesticated	Association Mapping	Chan YF; Jones FC; McConnell E ; et al. (2012) Parallel selection mapping using artificially selected mice reveals body weight control loci.	GP00000928	PRLHR P49683	Physiology	unknown	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Prolactin releasing hormone receptor (Prlhr/GPR10)	Mus musculus house mouse - (species)	Published - Accepted by Curator
PRR37-like Photoperiod-H1 (Ppd-H1)	Flowering time	Unknown, Unknown	Hordeum vulgare (species)	Domesticated	Linkage Mapping	Turner A; Beales J; Faure S ; et al. (2005) The pseudo-response regulator Ppd-H1 provides adaptation to photoperiod in barley. 1 Additional References Campoli C; Shtaya M; Davis SJ (2012) Expression conservation within the circadian clock of a monocot: natural variation at barley Ppd-H1 [...]	GP00000933	PRR37 Q0D3B6	Physiology	unknown	Hordeum vulgare (species)	Hordeum vulgare (species)	PRR37-like Photoperiod-H1 (Ppd-H1)	Hordeum vulgare (species)	Published - Accepted by Curator
Prx1 = Mhox = Prrx1	Limb length	Cis-regulatory, Unknown	Carollia perspicillata Seba's short-tailed bat - (species)	Intergeneric or Higher	Candidate Gene	Cretekos CJ; Wang Y; Green ED ; et al. (2008) Regulatory divergence modifies limb length between mammals.	GP00000934	Prrx1 P63013	Morphology	Not identified	Mus musculus house mouse - (species)	Carollia perspicillata Seba's short-tailed bat - (species)	Prx1 = Mhox = Prrx1	Carollia perspicillata Seba's short-tailed bat - (species)	Published - Accepted by Curator
PSMD13	Hematopoiesis (mean blood platelet volume)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001615	PSMD13 Q9UNM6	Physiology	A>G at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	PSMD13	Homo sapiens human - (species)	Published - Accepted by Curator
Pto	Pathogen resistance	Unknown, Unknown	Solanum lycopersicum tomato - (species)	Domesticated	Linkage Mapping	Martin GB; Brommonschenkel SH; Chunwongse J ; et al. (1993) Map-based cloning of a protein kinase gene conferring disease resistance in tomato.	GP00000937	pto P93215	Physiology	Not identified	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species)	Pto	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
Purple (Pr)	Plant color	Cis-regulatory, Unknown	Brassica oleracea var. botrytis (varietas)	Domesticated	Linkage Mapping	Chiu LW; Zhou X; Burke S ; et al. (2010) The purple cauliflower arises from activation of a MYB transcription factor.	GP00000939	MYB2 E5D8F5	Morphology	unknown	Brassica oleracea wild cabbage - (species)	Brassica oleracea var. botrytis (varietas)	Purple (Pr)	Brassica oleracea var. botrytis (varietas)	Published - Accepted by Curator
PVX_084940	Xenobiotic resistance (multiresistance to antimalarial drugs)	Unknown, Unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Intraspecific	Association Mapping	Pearson RD; Amato R; Auburn S ; et al. (2016) Genomic analysis of local variation and recent evolution in Plasmodium vivax.	GP00001487	PVX_084940 A5K0T0	Physiology	unknown	Plasmodium vivax malaria parasite P. vivax - (species)	Plasmodium vivax malaria parasite P. vivax - (species)	PVX_084940	Plasmodium vivax malaria parasite P. vivax - (species)	Published - Accepted by Curator
R-spondin-2 (RSPO2)	Hair length (moustache / eyebrows)	Cis-regulatory, Insertion	Canis lupus familiaris dog - (subspecies) D	Domesticated	Association Mapping	Cadieu E; Neff MW; Quignon P ; et al. (2009) Coat variation in the domestic dog is governed by variants in three genes.	GP00000945	Rspo2 Q8BFU0	Morphology	a 167bp insertion within the 3'UTR at position which leads to a threefold increase in transcription of RSPO2 in muzzle skin of dogs with furnishings	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	R-spondin-2 (RSPO2)	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
R2R3 MYB transcription factor	Trichome density (leaf)	Unknown, Unknown	Erythranthe guttata spotted monkey flower - (species)	Domesticated	Linkage Mapping	Hendrick MF; Finseth FR; Mathiasson ME ; et al. (2016) The genetics of extreme microgeographic adaptation: an integrated approach identifies a major gene u[...]	GP00001598	PELAN A0A060IEP7	Morphology	Unknown ; candidate indel in first intron and a nonsynonymous substitution (glutamine>lysine) in the 3rd exon	Erythranthe guttata spotted monkey flower - (species)	Erythranthe guttata spotted monkey flower - (species)	R2R3 MYB transcription factor	Erythranthe guttata spotted monkey flower - (species)	Published - Accepted by Curator
R2R3-Myb	Coloration (flowers)	Cis-regulatory, Unknown	Phlox drummondii (species)	Intraspecific	Linkage Mapping	Hopkins R; Rausher MD (2011) Identification of two genes causing reinforcement in the Texas wildflower Phlox drummondii.	GP00000948	H8ZS70	Morphology	unknown	Phlox drummondii (species)	Phlox drummondii (species)	R2R3-Myb	Phlox drummondii (species)	Published - Accepted by Curator
RAC1	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Borhan MH; Holub EB; Beynon JL ; et al. (2004) The arabidopsis TIR-NB-LRR gene RAC1 confers resistance to Albugo candida (white rust) and is depend[...]	GP00000949	ARAC3 Q38912	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RAC1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Rap2.7 (vgt1)	Flowering time	Cis-regulatory, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Salvi S; Sponza G; Morgante M ; et al. (2007) Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in m[...] 1 Additional References Buckler ES; Holland JB; Bradbury PJ (2009) The genetic architecture of maize flowering time.	GP00000951	RAP2-7 Q9SK03	Physiology	2kb-sequence located 70kb upstream of the Vg1 transcription start site - insertion of a miniature transposon (MITE) belonging to the Tourist family	Zea mays (species)	Zea mays (species)	Rap2.7 (vgt1)	Zea mays (species)	Published - Accepted by Curator
RB1	Body size (weight) Body size (bone length)	Unknown, Unknown	Gallus gallus chicken - (species)	Domesticated	Linkage Mapping	Zhang H; Liu SH; Zhang Q ; et al. (2011) Fine-mapping of quantitative trait loci for body weight and bone traits and positional cloning of th[...]	GP00000957		Morphology Morphology	unknown	Gallus gallus chicken - (species)	Gallus gallus chicken - (species)	RB1	Gallus gallus chicken - (species)	Published - Accepted by Curator
RCO-A	Leaf shape (simplification)	Cis-regulatory, Unknown	Capsella grandiflora (species)	Interspecific	Linkage Mapping	Sicard A; Thamm A; Marona C ; et al. (2014) Repeated evolutionary changes of leaf morphology caused by mutations to a homeobox gene.	GP00000961	RCO A0A023NDU4	Morphology	Complex haplotype	Capsella rubella (species)	Capsella grandiflora (species)	RCO-A	Capsella grandiflora (species)	Published - Accepted by Curator
Regulator of G-protein signaling 2 (RGS2)	Anxiety	Unknown, Unknown	Mus musculus house mouse - (species)	Intraspecific	Linkage Mapping	Yalcin B; Willis-Owen SA; Fullerton J ; et al. (2004) Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mic[...]	GP00000967	Rgs2 O08849	Behavior	unknown	Mus musculus house mouse - (species)	Mus musculus house mouse - (species)	Regulator of G-protein signaling 2 (RGS2)	Mus musculus house mouse - (species)	Published - Accepted by Curator
RHO2	Temperature tolerance / virulence	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Intraspecific	Linkage Mapping	Steinmetz LM; Sinha H; Richards DR ; et al. (2002) Dissecting the architecture of a quantitative trait locus in yeast. 1 Additional References Sinha H; Nicholson BP; Steinmetz LM (2006) Complex genetic interactions in a quantitative trait locus.	GP00000986	RHO2 P06781	Physiology	3'UTR polymorphism	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	RHO2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RnrS	Xenobiotic resistance (gemcitabine ; female fertility)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Association Mapping	King EG; Kislukhin G; Walters KN ; et al. (2014) Using Drosophila melanogaster to identify chemotherapy toxicity genes.	GP00001404	RnrS P48592	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	RnrS	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
RORB	gait (saltatorial locomotion)	Coding, SNP	Oryctolagus cuniculus rabbit - (species) D	Domesticated	Association Mapping	Carneiro M; Vieillard J; Andrade P ; et al. (2021) A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits.	GP00002343	RORB F1PET8	Behavior	a change from GT to AT in the 5’ donor site of intron 9 (chr1: 61,103,503bp). The mutation disrupts the normal splicing of RORB.	Oryctolagus cuniculus rabbit - (species)	Oryctolagus cuniculus rabbit - (species) D	RORB	Oryctolagus cuniculus rabbit - (species)	Published - Accepted by Curator
ROSE INTENSITY1 (ROI1)	Coloration (flowers)	Cis-regulatory, Unknown	Erythranthe lewisii (species)	Interspecific	Linkage Mapping	Yuan YW; Sagawa JM; Young RC ; et al. (2013) Genetic dissection of a major anthocyanin QTL contributing to pollinator-mediated reproductive isola[...]	GP00000996	ROI1 L7VK04	Morphology	unknown but coding variation was ruled out	Erythranthe lewisii (species)	Erythranthe lewisii (species)	ROSE INTENSITY1 (ROI1)	Erythranthe lewisii (species)	Published - Accepted by Curator
ROSEA	Coloration (flowers)	Unknown, Unknown	Antirrhinum majus snapdragon - (species)	Intraspecific	Linkage Mapping	Whibley AC; Langlade NB; Andalo C ; et al. (2006) Evolutionary paths underlying flower color variation in Antirrhinum.	GP00000997	ROS1 Q2VAZ7	Morphology	Not identified	Antirrhinum majus snapdragon - (species)	Antirrhinum majus snapdragon - (species)	ROSEA	Antirrhinum majus snapdragon - (species)	Published - Accepted by Curator
Rp3 cluster	Pathogen resistance	Unknown, Unknown	Zea mays (species)	Domesticated	Linkage Mapping	Webb CA; Richter TE; Collins NC ; et al. (2002) Genetic and molecular characterization of the maize rp3 rust resistance locus.	GP00000999	rp3-1 Q6PW75	Physiology	unknown	Zea mays (species)	Zea mays (species)	Rp3 cluster	Zea mays (species)	Published - Accepted by Curator
RPP1-WsA	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001002	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsA	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP1-WsB	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001003	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsB	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP1-WsC	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Botella MA; Parker JE; Frost LN ; et al. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasiti[...]	GP00001004	RPP1 F4J339	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP1-WsC	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP13	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Interspecific	Linkage Mapping	Rose LE; Bittner-Eddy PD; Langley CH ; et al. (2004) The maintenance of extreme amino acid diversity at the disease resistance gene, RPP13, in Arabidopsi[...]	GP00001005	RPP13 Q9M667	Physiology	Various haplotypes	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP13	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP2A-RPP2B	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Sinapidou E; Williams K; Nott L ; et al. (2004) Two TIR:NB:LRR genes are required to specify resistance to Peronospora parasitica isolate Cala2 in A[...]	GP00001006	RPP2A P51407	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP2A-RPP2B	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP4	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	van der Biezen EA; Freddie CT; Kahn K ; et al. (2002) Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mild[...]	GP00001007	RPP4 F4JNA9	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPP5	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	van der Biezen EA; Freddie CT; Kahn K ; et al. (2002) Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mild[...] 1 Additional References Nemri A; Atwell S; Tarone AM (2010) Genome-wide survey of Arabidopsis natural variation in downy mildew resistance using combined associ[...]	GP00001008	RPP5 F4JNB7	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPP5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
SaM + SaF	Hybrid incompatibility (F1 male sterility)	Unknown, Unknown	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Long Y; Zhao L; Niu B ; et al. (2008) Hybrid male sterility in rice controlled by interaction between divergent alleles of two adjacent ge[...] 1 Additional References Craig SM; Reagon M; Resnick LE (2014) Allele distributions at hybrid incompatibility loci facilitate the potential for gene flow between c[...]	GP00001022	SaF+ B6RRX2	Physiology	Intron structure + aa changes on two adjacent coding genes	Oryza sativa rice - (species)	Oryza sativa rice - (species)	SaM + SaF	Oryza sativa rice - (species)	Published - Accepted by Curator
scabrous	Bristle number (abdomen)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Lai C; Lyman RF; Long AD ; et al. (1994) Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Droso[...]	GP00001024	sca P21520	Morphology	unknown; but different sites than for thorax association	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	scabrous	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
scabrous	Bristle number (thorax)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Lai C; Lyman RF; Long AD ; et al. (1994) Naturally occurring variation in bristle number and DNA polymorphisms at the scabrous locus of Droso[...]	GP00001025	sca P21520	Morphology	unknown; but different sites than for abdomen association	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	scabrous	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
sdY	Sex determination	Unknown, Unknown	Teleostei teleost fishes - (infraclass)	Interspecific	Linkage Mapping	Yano A; Guyomard R; Nicol B ; et al. (2012) An immune-related gene evolved into the master sex-determining gene in rainbow trout, Oncorhynchus m[...]	GP00001033	sdy I7GVT3	Physiology	Novel gene evolution by modification of the irf9 gene; unrelated to sex determination	Oncorhynchus mykiss rainbow trout - (species)	Teleostei teleost fishes - (infraclass)	sdY	Teleostei teleost fishes - (infraclass)	Published - Accepted by Curator
SGLT1	Starch processing	Coding, Unknown	Canis lupus familiaris dog - (subspecies)	Domesticated	Association Mapping	Axelsson E; Ratnakumar A; Arendt ML ; et al. (2013) The genomic signature of dog domestication reveals adaptation to a starch-rich diet.	GP00001037	Slc5a1 Q9QXI6	Physiology	unknown	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies)	SGLT1	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
sid-2	Immune response (RNAi efficiency)	Unknown, Unknown	Caenorhabditis elegans (species)	Interspecific	Candidate Gene	Winston WM; Sutherlin M; Wright AJ ; et al. (2007) Caenorhabditis elegans SID-2 is required for environmental RNA interference.	GP00001051	sid-2 G5EEV9	Physiology	unknown	Caenorhabditis (genus)	Caenorhabditis elegans (species)	sid-2	Caenorhabditis elegans (species)	Published - Accepted by Curator
smooth	Bristle number (abdomen)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	zur Lage P; Shrimpton AD; Flavell AJ ; et al. (1997) Genetic and molecular analysis of smooth, a quantitative trait locus affecting bristle number in Dro[...]	GP00001996		Morphology	exact causing mutation(s) unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	smooth	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
SOD3	Oxidative stress resistance Blood pressure	Unknown, Unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Intraspecific	Association Mapping	Jones FC; Chan YF; Schmutz J ; et al. (2012) A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence i[...]	GP00001380	SOD3 P08294	Physiology Physiology	unknown	Gasterosteus aculeatus three-spined stickleback - (species)	Gasterosteus aculeatus three-spined stickleback - (species)	SOD3	Gasterosteus aculeatus three-spined stickleback - (species)	Published - Accepted by Curator
SR-CII	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00001071	Sr-CII Q5ELW9	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	SR-CII	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
srx-43	Pheromone response (ascaroside)	Cis-regulatory, Unknown	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Greene JS; Brown M; Dobosiewicz M ; et al. (2016) Balancing selection shapes density-dependent foraging behaviour. 1 Additional References Greene JS; Dobosiewicz M; Butcher RA (2016) Regulatory changes in two chemoreceptor genes contribute to a Caenorhabditis elegans QTL for foragin[...]	GP00001319	srx-43 O45767	Physiology	unknown	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	srx-43	Caenorhabditis elegans (species)	Published - Accepted by Curator
Style2.1	Flower morphology (style length) Autogamy	Cis-regulatory, Unknown	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Chen KY; Cong B; Wing R ; et al. (2007) Changes in regulation of a transcription factor lead to autogamy in cultivated tomatoes.	GP00001081	100301942 B6CG44	Morphology Physiology	Not identified	Solanum pennellii (species)	Solanum lycopersicum tomato - (species) D	Style2.1	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
sulfate transporter 1;1	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001429	SULTR1;1 Q9SAY1	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	sulfate transporter 1;1	Arabidopsis arenosa (species)	Published - Accepted by Curator
Svb/ovo	Trichome pattern (larva)	Cis-regulatory, Unknown	Drosophila ezoana (species)	Interspecific	Candidate Gene	Frankel N; Wang S; Stern DL (2012) Conserved regulatory architecture underlies parallel genetic changes and convergent phenotypic evolu[...] 1 Additional References Sucena E; Delon I; Jones I (2003) Regulatory evolution of shavenbaby/ovo underlies multiple cases of morphological parallelism.	GP00001086	ovo P51521	Morphology	unknown	virilis group (species group)	Drosophila ezoana (species)	Svb/ovo	Drosophila ezoana (species)	Published - Accepted by Curator
SWS2	Xenobiotic resistance (alcohol, ethanol)	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Swinnen S; Schaerlaekens K; Pais T ; et al. (2012) Identification of novel causative genes determining the complex trait of high ethanol tolerance in y[...]	GP00001088	SWS2 P53937	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SWS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SWS2	Sporulation efficiency	Cis-regulatory, Unknown	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Ben-Ari G; Zenvirth D; Sherman A ; et al. (2006) Four linked genes participate in controlling sporulation efficiency in budding yeast.	GP00001089	SWS2 P53937	Physiology	unknown	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	SWS2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
tan	Coloration (abdomen)	Cis-regulatory, Unknown	Drosophila novamexicana (species) D	Intraspecific	Linkage Mapping	Wittkopp PJ; Stewart EE; Arnold LL ; et al. (2009) Intraspecific polymorphism to interspecific divergence: genetics of pigmentation in Drosophila.	GP00001098	t Q9W369	Morphology	2.7kb non-coding interval; 13 SNPs + 2 indels differing between species	Drosophila americana (species)	Drosophila novamexicana (species) D	tan	Drosophila novamexicana (species)	Published - Accepted by Curator
TAS1R1	Taste sensitivity (sugar)	Coding, Unknown	Calypte anna Anna's hummingbird - (species) D	Interspecific	Candidate Gene	Baldwin MW; Toda Y; Nakagita T ; et al. (2014) Sensory biology. Evolution of sweet taste perception in hummingbirds by transformation of the ancest[...]	GP00001307	T1R1 A0A088DBT6	Physiology	unknown	Gallus gallus chicken - (species)	Calypte anna Anna's hummingbird - (species) D	TAS1R1	Calypte anna Anna's hummingbird - (species)	Published - Accepted by Curator
Tbx5	Limb Identity (feathered feet)	Cis-regulatory, Unknown	Columba livia rock pigeon - (species) D	Domesticated	Linkage Mapping	Domyan ET; Kronenberg Z; Infante CR ; et al. (2016) Molecular shifts in limb identity underlie development of feathered feet in two domestic avian speci[...]	GP00001114	TBX5 Q9PWE8	Morphology	unknown	Columba livia rock pigeon - (species)	Columba livia rock pigeon - (species) D	Tbx5	Columba livia rock pigeon - (species)	Published - Accepted by Curator
Tehao	Pathogen resistance	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Candidate Gene	Lazzaro BP; Sackton TB; Clark AG (2006) Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria.	GP00001115	Tehao Q9VJX9	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Tehao	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
teosinte branched 1 (tb1) = IntC	Plant architecture Inflorescence architecture	Coding, Unknown	Hordeum vulgare (species)	Domesticated	Association Mapping	Ramsay L; Comadran J; Druka A ; et al. (2011) INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domes[...]	GP00001117	TB1 Q93WI2	Morphology Morphology	Large haplotypes; unknown	Hordeum vulgare (species)	Hordeum vulgare (species)	teosinte branched 1 (tb1) = IntC	Hordeum vulgare (species)	Published - Accepted by Curator
TFL1/FvTFL1	Flowering time Seasonal growth	Cis-regulatory, Unknown	Fragaria vesca wild strawberry - (species)	Intraspecific	Linkage Mapping	Koskela EA; Mouhu K; Albani MC ; et al. (2012) Mutation in TERMINAL FLOWER1 reverses the photoperiodic requirement for flowering in the wild strawb[...]	GP00001120	TFL1 P93003	Physiology Physiology	unknown	Fragaria vesca wild strawberry - (species)	Fragaria vesca wild strawberry - (species)	TFL1/FvTFL1	Fragaria vesca wild strawberry - (species)	Published - Accepted by Curator
TICAM1	Pathogen resistance (Trypanosoma)	Coding, Unknown	Bos taurus cattle - (species)	Domesticated	Linkage Mapping	Noyes H; Brass A; Obara I ; et al. (2011) Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypa[...]	GP00001128	TICAM1 Q8IUC6	Physiology	unknown	Bos oxen, cattle - (genus)	Bos taurus cattle - (species)	TICAM1	Bos taurus cattle - (species)	Published - Accepted by Curator
tra-2	Fertility (self-fertility; hermaphrodite spermatogenesis)	Cis-regulatory, Insertion	Caenorhabditis elegans (species)	Interspecific	Candidate Gene	Kuwabara PE (1996) Interspecies comparison reveals evolution of control regions in the nematode sex-determining gene tr[...] 2 Additional References Haag ES; Kimble J (2000) Regulatory elements required for development of caenorhabditis elegans hermaphrodites are conserved [...] Beadell AV; Liu Q; Johnson DM (2011) Independent recruitments of a translational regulator in the evolution of self-fertile nematodes.	GP00001132	tra-2 P34709	Physiology	Tandem duplication of GLD-1 binding sites in 3'UTR; see also fog-2 entry	Caenorhabditis briggsae (species)	Caenorhabditis elegans (species)	tra-2	Caenorhabditis elegans (species)	Published - Accepted by Curator
Trichohyalin	Hair type (straight)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Medland SE; Nyholt DR; Painter JN ; et al. (2009) Common variants in the trichohyalin gene are associated with straight hair in Europeans.	GP00001134	TCHH Q07283	Morphology	Not identified	Homo sapiens human - (species)	Homo sapiens human - (species)	Trichohyalin	Homo sapiens human - (species)	Published - Accepted by Curator
TRIP11 (=GMAP-210)	Body size (height)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Lettre G (2011) Recent progress in the study of the genetics of height.	GP00001138	TRIP11 Q15643	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	TRIP11 (=GMAP-210)	Homo sapiens human - (species)	Published - Accepted by Curator
TRPM1	Coloration (coat)	Cis-regulatory, Insertion	Equus caballus horse - (species) D	Intraspecific	Linkage Mapping	Bellone RR; Forsyth G; Leeb T ; et al. (2010) Fine-mapping and mutation analysis of TRPM1: a candidate gene for leopard complex (LP) spotting and [...] 3 Additional References Pruvost M; Bellone R; Benecke N (2011) Genotypes of predomestic horses match phenotypes painted in Paleolithic works of cave art. Bellone RR; Holl H; Setaluri V (2013) Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness a[...] Druml T; Grilz-Seger G; Neuditschko M (2017) Phenotypic and Genetic Analysis of the Leopard Complex Spotting in Noriker Horses.	GP00001140	TRPM1 Q7Z4N2	Morphology	a 1378 bp retroviral LTR insertion in intron 1 of TRPM1	Equus caballus horse - (species)	Equus caballus horse - (species) D	TRPM1	Equus caballus horse - (species)	Published - Accepted by Curator
two pore channel	Xenobiotic resistance (soil contamination; serpentine)	Unknown, Unknown	Arabidopsis arenosa (species) D	Intraspecific	Association Mapping	Arnold BJ; Lahner B; DaCosta JM ; et al. (2016) Borrowed alleles and convergence in serpentine adaptation.	GP00001433	TPC1 Q94KI8	Physiology	unknown	Arabidopsis arenosa (species)	Arabidopsis arenosa (species) D	two pore channel	Arabidopsis arenosa (species)	Published - Accepted by Curator
Tyramine receptor 3	Exploration decision	Unknown, Unknown	Caenorhabditis elegans (species)	Intraspecific	Linkage Mapping	Bendesky A; Tsunozaki M; Rockman MV ; et al. (2011) Catecholamine receptor polymorphisms affect decision-making in C. elegans.	GP00001141	tyra-3 Q7JNP9	Behavior	Non-coding	Caenorhabditis elegans (species)	Caenorhabditis elegans (species)	Tyramine receptor 3	Caenorhabditis elegans (species)	Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)	Coloration (eyes; hair; skin)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Frudakis T; Thomas M; Gaskin Z ; et al. (2003) Sequences associated with human iris pigmentation. 1 Additional References Sulem P; Gudbjartsson DF; Stacey SN (2008) Two newly identified genetic determinants of pigmentation in Europeans.	GP00001157	Tyrp1 P07147	Morphology	unknown	Homo sapiens human - (species)	Homo sapiens human - (species)	tyrosinase-related protein 1 (TYRP1)	Homo sapiens human - (species)	Published - Accepted by Curator
Ubiquitin conjugating enzyme E2H (Ubc-E2H)	Pathogen resistance (Drosophila C virus & cricket paralysis virus)	Unknown, Unknown	Drosophila melanogaster fruit fly - (species) D	Experimental Evolution	Association Mapping	Martins NE; Faria VG; Nolte V ; et al. (2014) Host adaptation to viruses relies on few genes with different cross-resistance properties.	GP00001480	UbcE2H Q7JW03	Physiology	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Ubiquitin conjugating enzyme E2H (Ubc-E2H)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
UDP-glycosyltransferase 89A2	Plant secondary metabolites (xylosides vs. glucosides ratio)	Unknown, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Li X; Svedin E; Mo H ; et al. (2014) Exploiting natural variation of secondary metabolism identifies a gene controlling the glycosylation[...]	GP00001278	UGT89A2 Q9LZD8	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	UDP-glycosyltransferase 89A2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Ultrabithorax (Ubx)	Trichome pattern (leg)	Cis-regulatory, Unknown	Drosophila simulans (species)	Interspecific	Candidate Gene	Stern DL (1998) A role of Ultrabithorax in morphological differences between Drosophila species.	GP00001161	Ubx P83949	Morphology	Not identified	Drosophila melanogaster fruit fly - (species)	Drosophila simulans (species)	Ultrabithorax (Ubx)	Drosophila simulans (species)	Published - Accepted by Curator
Unpaired-like	Wing shape (sex-specific) Wing size	Cis-regulatory, Unknown	Nasonia giraulti (species)	Interspecific	Linkage Mapping	Loehlin DW; Werren JH (2012) Evolution of shape by multiple regulatory changes to a growth gene.	GP00001163	upd1 O96525	Morphology Morphology	three regions	Nasonia vitripennis jewel wasp - (species)	Nasonia giraulti (species)	Unpaired-like	Nasonia giraulti (species)	Published - Accepted by Curator
Vanaso / disc losts	Olfactory behavior	Unknown, Unknown	Drosophila melanogaster fruit fly - (species)	Intraspecific	Linkage Mapping	Fanara JJ; Robinson KO; Rollmann SM ; et al. (2002) Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior.	GP00001164	dlt Q8T626	Behavior	unknown	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species)	Vanaso / disc losts	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Vertnin (VRTN)	Vertebrae number	Cis-regulatory, Unknown	Sus scrofa domesticus domestic pig - (subspecies)	Domesticated	Linkage Mapping	Mikawa S; Sato S; Nii M ; et al. (2011) Identification of a second gene associated with variation in vertebral number in domestic pigs.	GP00001165	Vrtn Q3SYK4	Morphology	unknown ; observed transposon insertion in intron and promoter variation	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies)	Vertnin (VRTN)	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
Vertnin (VRTN) [possibly a pseudo-replicate of other Pig entry]	Vertebrae number	Unknown, Unknown	Sus scrofa domesticus domestic pig - (subspecies)	Domesticated	Linkage Mapping	Ren DR; Ren J; Ruan GF ; et al. (2012) Mapping and fine mapping of quantitative trait loci for the number of vertebrae in a White Duroc × C[...]	GP00001166	Vrtn Q3SYK4	Morphology	unknown	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies)	Vertnin (VRTN) [possibly a pseudo-replicate of other Pig entry]	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
VGLL3 (vestigial-like family member 3 gene )	Age of sexual maturity	Unknown, Unknown	Salmo salar Atlantic salmon - (species)	Intraspecific	Association Mapping	Barson NJ; Aykanat T; Hindar K ; et al. (2015) Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon. 1 Additional References Ayllon F; Kjærner-Semb E; Furmanek T (2015) The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) M[...]	GP00001167	VGLL3 A8MV65	Physiology	candidate amino-acid substitutions	Salmo salar Atlantic salmon - (species)	Salmo salar Atlantic salmon - (species)	VGLL3 (vestigial-like family member 3 gene )	Salmo salar Atlantic salmon - (species)	Published - Accepted by Curator
VRN1	Flowering time	Cis-regulatory, Unknown	Triticum monococcum (species)	Domesticated	Linkage Mapping	Yan L; Loukoianov A; Tranquilli G ; et al. (2003) Positional cloning of the wheat vernalization gene VRN1.	GP00001185	VRN1 Q8L3W1	Physiology	Not identified	Triticum monococcum (species)	Triticum monococcum (species)	VRN1	Triticum monococcum (species)	Published - Accepted by Curator
VvMYBA1	Coloration (fruit)	Unknown, Unknown	Vitis vinifera wine grape - (species)	Domesticated	Linkage Mapping	Fournier-Level A; Le Cunff L; Gomez C ; et al. (2009) Quantitative genetic bases of anthocyanin variation in grape (Vitis vinifera L. ssp. sativa) berry: [...]	GP00001193	VvmybA1 Q6L973	Morphology	Gret1 insertion polymorphism + R188S + Q213P	Vitis vinifera wine grape - (species)	Vitis vinifera wine grape - (species)	VvMYBA1	Vitis vinifera wine grape - (species)	Published - Accepted by Curator
Waxy /GBSS	Amylose content	Cis-regulatory, Deletion	Hordeum vulgare (species) D	Domesticated	Linkage Mapping	Domon E; Fuijita M; Ishikawa N (2002) The insertion/deletion polymorphisms in the waxy gene of barley genetic resources from East Asia.	GP00001197	waxy Q8L699	Physiology	403-bp deletion spanning from position –129 bp to position +274 relative to the deduced starting point of transcription in the barley waxy gene and	Hordeum vulgare (species)	Hordeum vulgare (species) D	Waxy /GBSS	Hordeum vulgare (species)	Published - Accepted by Curator
WDR66	Hematopoiesis (mean blood platelet volume)	Unknown, Unknown	Homo sapiens human - (species)	Intraspecific	Association Mapping	Guo MH; Nandakumar SK; Ulirsch JC ; et al. (2017) Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mech[...]	GP00001604	WDR66 Q8TBY9	Physiology	A>G at the associated SNP	Homo sapiens human - (species)	Homo sapiens human - (species)	WDR66	Homo sapiens human - (species)	Published - Accepted by Curator
WRR4	Pathogen resistance	Coding, Unknown	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Borhan MH; Gunn N; Cooper A ; et al. (2008) WRR4 encodes a TIR-NB-LRR protein that confers broad-spectrum white rust resistance in Arabidopsis t[...]	GP00001215	ADR2 Q9C7X0	Physiology	unknown	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	WRR4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Xa1	Pathogen resistance	Unknown, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Yoshimura S; Yamanouchi U; Katayose Y ; et al. (1998) Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation.	GP00001216	XA1 A0A0H5AGW3	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa1	Oryza sativa rice - (species)	Published - Accepted by Curator
Xa21	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Song WY; Wang GL; Chen LL ; et al. (1995) A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21.	GP00001217	Xa21 A0PIA3	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa21	Oryza sativa rice - (species)	Published - Accepted by Curator
Xa26	Pathogen resistance	Coding, Unknown	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Sun X; Cao Y; Yang Z ; et al. (2004) Xa26, a gene conferring resistance to Xanthomonas oryzae pv. oryzae in rice, encodes an LRR receptor[...]	GP00001218	Xa26 Q00KZ8	Physiology	unknown	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Xa26	Oryza sativa rice - (species)	Published - Accepted by Curator
Xmrk	Hybrid incompatibility (melanoma)	Unknown, Unknown	Xiphophorus hellerii green swordtail - (species)	Interspecific	Linkage Mapping	Adam D; Dimitrijevic N; Schartl M (1993) Tumor suppression in Xiphophorus by an accidentally acquired promoter. 1 Additional References Schartl M (2008) Evolution of Xmrk: an oncogene, but also a speciation gene?	GP00001219	xmrk P13388	Physiology	Various	Xiphophorus maculatus southern platyfish - (species)	Xiphophorus hellerii green swordtail - (species)	Xmrk	Xiphophorus hellerii green swordtail - (species)	Published - Accepted by Curator
Y	Coloration (fruit)	Coding, Insertion	Sorghum bicolor sorghum - (species) D	Domesticated	Candidate Gene	Chopra S; Brendel V; Zhang J ; et al. (1999) Molecular characterization of a mutable pigmentation phenotype and isolation of the first active tra[...]	GP00002068	P1 O24579	Morphology	insertion of a transposable element named Candystripe1 (Cs1) in the second intron of the Y gene - Cs1 is 23,018 bp in size and is bordered by 20-bp terminal inverted repeat sequences. It generated a 3-bp target site duplication upon insertion within the Y gene. Cs1 shares features of the CACTA superfamily of transposons.	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species) D	Y	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
ZmCCT	Flowering time	Cis-regulatory, Insertion	Zea mays (species) D	Domesticated	Linkage Mapping	Ducrocq S; Giauffret C; Madur D ; et al. (2009) Fine mapping and haplotype structure analysis of a major flowering time quantitative trait locus on [...] 2 Additional References Hung HY; Shannon LM; Tian F (2012) ZmCCT and the genetic basis of day-length adaptation underlying the postdomestication spread of maiz[...] Yang Q; Li Z; Li W (2013) CACTA-like transposable element in ZmCCT attenuated photoperiod sensitivity and accelerated the post[...]	GP00001227	GHD7 E5RQA1	Physiology	insertion of a CACTA-like transposon into the promoter of ZmCCT. This insertion suppresses ZmCCT expression through methylation and reduces maize sensitivity to photoperiod.	Zea mays (species)	Zea mays (species) D	ZmCCT	Zea mays (species)	Published - Accepted by Curator
Zygotic hybrid rescue	F1 lethality (female-limited)	Unknown, Unknown	Drosophila simulans (species)	Interspecific	Linkage Mapping	Ferree PM; Barbash DA (2009) Species-specific heterochromatin prevents mitotic chromosome segregation to cause hybrid lethality i[...]	GP00001228		Physiology	Heterochromatin incompatibilitity	Drosophila melanogaster fruit fly - (species)	Drosophila simulans (species)	Zygotic hybrid rescue	Drosophila simulans (species)	Published - Accepted by Curator