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Gene	Trait	Mutation	Taxon B	Taxonomic Status	Evidence	Main Reference	Gephe ID	UniProtKB	Trait Category	Mutation Details	Taxon A	Taxon B	Edit Gene-GePhe	Taxon B	Status
ABCA1	Coloration (feathers) Cholesterol metabolism	Coding, SNP N	Gallus gallus chicken - (species) D	Domesticated	Linkage Mapping	Attie AD; Hamon Y; Brooks-Wilson AR ; et al. (2002) Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of t[...]	GP00001682	Abca1 P41233	Morphology; Physiology Morphology; Physiology	amino acid substitution at a residue that is conserved in the ABCA1 gene between human; mouse; chicken; and Takifugu rubripes. Generation of a mouse ABCA1 protein with the mutation disrupts protein function. N	Gallus gallus chicken - (species)	Gallus gallus chicken - (species) D	ABCA1	Gallus gallus chicken - (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Indel N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Linkage Mapping	Tay WT; Mahon RJ; Heckel DG ; et al. (2015) Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transpo[...]	GP00000002	ABCA2 A0A0S0G7V0	Physiology	65bp indel in exon16 inducing a frameshift N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	ABCA2	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Deletion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Tay WT; Mahon RJ; Heckel DG ; et al. (2015) Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transpo[...]	GP00000003	ABCA2 A0A0S0G7V0	Physiology	5bp deletion inducing a frameshift N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	ABCA2	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Tay WT; Mahon RJ; Heckel DG ; et al. (2015) Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transpo[...]	GP00000004	ABCA2 A0A0S0G7V0	Physiology	5bp (GAATA) nucleotide duplication inducing a frameshift N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	ABCA2	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Insertion N	Trichoplusia ni cabbage looper - (species) D	Intraspecific	Linkage Mapping	Yang X; Chen W; Song X ; et al. (2019) Mutation of ABC transporter ABCA2 confers resistance to Bt toxin Cry2Ab in Trichoplusia ni.	GP00002054	ABCA2 A0A0S0G7V0	Physiology	insertion of a transposon Tntransib (2581 bp) in ABCA2 which changes splicing sites in the transcript and lead to an indel in the coding region: change of 1551VETLAHALGFLRHLDKR1567 into 1551AHWGK- LYGSNTQN1563 N	Trichoplusia ni cabbage looper - (species)	Trichoplusia ni cabbage looper - (species) D	ABCA2	Trichoplusia ni cabbage looper - (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Deletion N	Helicoverpa punctigera (species) D	Intraspecific	Candidate Gene	Tay WT; Mahon RJ; Heckel DG ; et al. (2015) Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transpo[...]	GP00002056	ABCA2 A0A0S0G7V0	Physiology	14bp deletion resulting in missense mutations. N	Helicoverpa punctigera (species)	Helicoverpa punctigera (species) D	ABCA2	Helicoverpa punctigera (species)	Published - Accepted by Curator
ABCA2	Xenobiotic resistance (insecticide; Bt Cry2Ab toxin)	Coding, Insertion N	Pectinophora gossypiella pink bollworm - (species) D	Intraspecific	Candidate Gene	Mathew LG; Ponnuraj J; Mallappa B ; et al. (2018) ABC transporter mis-splicing associated with resistance to Bt toxin Cry2Ab in laboratory- and field-[...]	GP00002057	ABCA2 A0A0S0G7V0	Physiology	loss of exon 6 caused by alternative splicing N	Pectinophora gossypiella pink bollworm - (species)	Pectinophora gossypiella pink bollworm - (species) D	ABCA2	Pectinophora gossypiella pink bollworm - (species)	Published - Accepted by Curator
ABCB1	Plant size (dwarfism)	Coding, Insertion N	Sorghum bicolor sorghum - (species)	Domesticated	Candidate Gene	Multani DS; Briggs SP; Chamberlin MA ; et al. (2003) Loss of an MDR transporter in compact stalks of maize br2 and sorghum dw3 mutants.	GP00000007	ABCB1 Q9ZR72	Morphology	882bp direct duplication in exon 5 of the dw3 allele driving loss-of-function N	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species)	ABCB1	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
Abcb4	Biliary Phospholipid Level (low)	Coding, Unknown N	Cavia porcellus domestic guinea pig - (species)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000008	Abcb4 P21440	Physiology	pseudogenization N	Mammalia mammals - (class)	Cavia porcellus domestic guinea pig - (species)	Abcb4	Cavia porcellus domestic guinea pig - (species)	Published - Accepted by Curator
Abcb4	Biliary Phospholipid Level (low)	Coding, Unknown N	Equus caballus horse - (species)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000009	Abcb4 P21440	Physiology	pseudogenization N	Mammalia mammals - (class)	Equus caballus horse - (species)	Abcb4	Equus caballus horse - (species)	Published - Accepted by Curator
ABCC2	Xenobiotic resistance (insecticide)	Coding, Deletion N	Heliothis virescens tobacco budworm - (species) D	Intraspecific	Linkage Mapping	Gahan LJ; Pauchet Y; Vogel H ; et al. (2010) An ABC transporter mutation is correlated with insect resistance to Bacillus thuringiensis Cry1Ac to[...]	GP00000012	ABCC2 A0A0E3ZDK3	Physiology	22bp deletion N	Heliothis virescens tobacco budworm - (species)	Heliothis virescens tobacco budworm - (species) D	ABCC2	Heliothis virescens tobacco budworm - (species)	Published - Accepted by Curator
ABCC2	Xenobiotic resistance (insecticide)	Coding, Deletion N	Plutella xylostella diamondback moth - (species) D	Intraspecific	Linkage Mapping	Baxter SW; Badenes-Pérez FR; Morrison A ; et al. (2011) Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera.	GP00000013	ABCC2 A0A0E3ZDK3	Physiology	30bp deletion N	Plutella xylostella diamondback moth - (species)	Plutella xylostella diamondback moth - (species) D	ABCC2	Plutella xylostella diamondback moth - (species)	Published - Accepted by Curator
ABCC2	Xenobiotic resistance (insecticide; Bt toxins)	Coding, Deletion N	Spodoptera exigua beet armyworm - (species) D	Intraspecific	Linkage Mapping	Park Y; González-Martínez RM; Navarro-Cerrillo G ; et al. (2014) ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysi[...]	GP00001439		Physiology	About 500 nt genomic deletion over 2 exons involving 246 nt coding 82aa N	Spodoptera exigua beet armyworm - (species)	Spodoptera exigua beet armyworm - (species) D	ABCC2	Spodoptera exigua beet armyworm - (species)	Published - Accepted by Curator
ABO histo blood group glycosyltransferase	ABO antigen blood type	Coding, Deletion N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Yamamoto F; Hakomori S (1990) Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid [...] 1 Additional References Calafell F; Roubinet F; Ramírez-Soriano A (2008) Evolutionary dynamics of the human ABO gene.	GP00000019	ABO P16442	Physiology	1bp deletion (258G) resulting in frameshift N	Homo sapiens human - (species)	Homo sapiens human - (species) D	ABO histo blood group glycosyltransferase	Homo sapiens human - (species)	Published - Accepted by Curator
ABO histo blood group glycosyltransferase	ABO antigen blood type	Coding, Insertion N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Hosseini-Maaf B; Irshaid NM; Hellberg A ; et al. (2005) New and unusual O alleles at the ABO locus are implicated in unexpected blood group phenotypes. 1 Additional References Yazer MH; Hosseini-Maaf B; Olsson ML (2008) Blood grouping discrepancies between ABO genotype and phenotype caused by O alleles.	GP00000021	ABO P16442	Physiology	1bp insertion resulting in premature stop codon N	Homo sapiens human - (species)	Homo sapiens human - (species) D	ABO histo blood group glycosyltransferase	Homo sapiens human - (species)	Published - Accepted by Curator
ABO histo blood group glycosyltransferase	ABO antigen blood type	Coding, SNP N	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Hosseini-Maaf B; Irshaid NM; Hellberg A ; et al. (2005) New and unusual O alleles at the ABO locus are implicated in unexpected blood group phenotypes. 1 Additional References Yazer MH; Hosseini-Maaf B; Olsson ML (2008) Blood grouping discrepancies between ABO genotype and phenotype caused by O alleles.	GP00000022	ABO P16442	Physiology	1bp change resulting in stop codon N	Homo sapiens human - (species)	Homo sapiens human - (species)	ABO histo blood group glycosyltransferase	Homo sapiens human - (species)	Published - Accepted by Curator
Agouti	Coloration (coat; dorso-ventral)	Gene Loss, Deletion N	Peromyscus polionotus oldfield mouse - (species)	Intraspecific	Candidate Gene	Kingsley EP; Manceau M; Wiley CD ; et al. (2009) Melanism in peromyscus is caused by independent mutations in agouti.	GP00000055	Asip Q03288	Morphology	125kb deletion including 5' CDS of Agouti N	Peromyscus polionotus oldfield mouse - (species)	Peromyscus polionotus oldfield mouse - (species)	Agouti	Peromyscus polionotus oldfield mouse - (species)	Published - Accepted by Curator
Agouti	Coloration (coat; dorso-ventral)	Coding, SNP N	Peromyscus polionotus oldfield mouse - (species)	Intraspecific	Candidate Gene	Kingsley EP; Manceau M; Wiley CD ; et al. (2009) Melanism in peromyscus is caused by independent mutations in agouti.	GP00000056	Asip Q03288	Morphology	Premature stop codon at residue 65 N	Peromyscus polionotus oldfield mouse - (species)	Peromyscus polionotus oldfield mouse - (species)	Agouti	Peromyscus polionotus oldfield mouse - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, Deletion N	Equus caballus horse - (species) D	Intraspecific	Linkage Mapping	Rieder S; Taourit S; Mariat D ; et al. (2001) Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their associati[...] 1 Additional References Pruvost M; Bellone R; Benecke N (2011) Genotypes of predomestic horses match phenotypes painted in Paleolithic works of cave art.	GP00000062	Asip Q03288	Morphology	11bp deletion in exon 2: g.2174_2184del11 c.191_201del N	Equus caballus horse - (species)	Equus caballus horse - (species) D	Agouti	Equus caballus horse - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, Deletion N	Felis catus domestic cat - (species) D	Domesticated	Linkage Mapping	Eizirik E; Yuhki N; Johnson WE ; et al. (2003) Molecular genetics and evolution of melanism in the cat family.	GP00000063	Asip Q03288	Morphology	Deletion of nt 123-124 N	Felis catus domestic cat - (species)	Felis catus domestic cat - (species) D	Agouti	Felis catus domestic cat - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, SNP N	Panthera pardus leopard - (species) D	Intraspecific	Candidate Gene	Schneider A; David VA; Johnson WE ; et al. (2012) How the leopard hides its spots: ASIP mutations and melanism in wild cats.	GP00000065	Asip Q03288	Morphology	nonsense mutation located in exon 4 (C333A) predicted to introduce a stop codon at amino acid position 111 N	Panthera pardus leopard - (species)	Panthera pardus leopard - (species) D	Agouti	Panthera pardus leopard - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, Deletion N	Vulpes vulpes red fox - (species) D	Domesticated	Candidate Gene	Våge DI; Lu D; Klungland H ; et al. (1997) A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes.	GP00000067	Asip Q03288	Morphology	166 bp deletion in exon 1 N	Vulpes vulpes red fox - (species)	Vulpes vulpes red fox - (species) D	Agouti	Vulpes vulpes red fox - (species)	Published - Accepted by Curator
Agouti	Coloration (feathers)	Coding, Deletion N	Coturnix japonica Japanese quail - (species) D	Domesticated	Linkage Mapping	Hiragaki T; Inoue-Murayama M; Miwa M ; et al. (2008) Recessive black is allelic to the yellow plumage locus in Japanese quail and associated with a frame[...]	GP00000068	Asip Q03288	Morphology	8bp frameshift deletion N	Coturnix japonica Japanese quail - (species)	Coturnix japonica Japanese quail - (species) D	Agouti	Coturnix japonica Japanese quail - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, SNP N	Leopardus colocolo Colocolo - (species) D	Intraspecific	Candidate Gene	Schneider A; Henegar C; Day K ; et al. (2015) Recurrent evolution of melanism in South American felids.	GP00001731	Asip Q03288	Morphology	Arg to Cys substitution in the C-terminal region of ASIP (p.R120C) lies in the critical RFF loop (e.g. a triplet motif made of one arginine and two phenylalanine residues) required for binding to the MC1R N	Leopardus colocolo Colocolo - (species)	Leopardus colocolo Colocolo - (species) D	Agouti	Leopardus colocolo Colocolo - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, SNP N	Leopardus guigna Kodkod - (species) D	Intraspecific	Candidate Gene	Schneider A; Henegar C; Day K ; et al. (2015) Recurrent evolution of melanism in South American felids.	GP00001732	Asip Q03288	Morphology	Cys to Tyr substitution in ASIP (p.C126Y) which affects the key disulfide bond that stabilizes the RFF loop N	Leopardus guigna Kodkod - (species)	Leopardus guigna Kodkod - (species) D	Agouti	Leopardus guigna Kodkod - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Gene Loss, Deletion N	Peromyscus maniculatus North American deer mouse - (species)	Intraspecific	Candidate Gene	Kingsley EP; Manceau M; Wiley CD ; et al. (2009) Melanism in peromyscus is caused by independent mutations in agouti.	GP00001975	Asip Q03288	Morphology	125kb deletion ; recessive mutation N	Peromyscus maniculatus North American deer mouse - (species)	Peromyscus maniculatus North American deer mouse - (species)	Agouti	Peromyscus maniculatus North American deer mouse - (species)	Published - Accepted by Curator
Agouti	Coloration (coat)	Coding, SNP N	Peromyscus maniculatus North American deer mouse - (species)	Intraspecific	Association Mapping	Kingsley EP; Manceau M; Wiley CD ; et al. (2009) Melanism in peromyscus is caused by independent mutations in agouti.	GP00001976	Asip Q03288	Morphology	recessive mutation at nucleotide position 193 (in exon 3) resulting in a change from glutamine to a stop codon at amino acid position 65 (Q65term) N	Peromyscus maniculatus North American deer mouse - (species)	Peromyscus maniculatus North American deer mouse - (species)	Agouti	Peromyscus maniculatus North American deer mouse - (species)	Published - Accepted by Curator
Agouti (ASIP)	Coloration (coat) Lifespan	2 Mutations: Coding N	Ovis aries sheep - (species) D	Intraspecific	Linkage Mapping	Gratten J; Pilkington JG; Brown EA ; et al. (2010) The genetic basis of recessive self-colour pattern in a wild sheep population. 1 Additional References Gratten J; Pilkington JG; Brown EA (2012) Selection and microevolution of coat pattern are cryptic in a wild population of sheep.	GP00001356	Asip Q03288	Morphology Physiology	2 mutations	Ovis aries sheep - (species)	Ovis aries sheep - (species) D	Agouti (ASIP)	Ovis aries sheep - (species)	Published - Accepted by Curator
Agouti (ASIP)	Coloration (coat)	Coding, Insertion N	Oryctolagus cuniculus rabbit - (species) D	Domesticated	Candidate Gene	Fontanesi L; Forestier L; Allain D ; et al. (2010) Characterization of the rabbit agouti signaling protein (ASIP) gene: transcripts and phylogenetic an[...] 1 Additional References Sakuma Y; Matsunami M; Takada T (2019) Multiple Conserved Elements Structuring Inverted Repeats in the Mammalian Coat Color-Related Gene As[...]	GP00001968	Asip Q03288	Morphology	an insertion in exon 2 of the black nonagouti allele = c.5_6insA mutation which causes a frameshift and a predicted truncated protein of only 21 amino acids N	Oryctolagus cuniculus rabbit - (species)	Oryctolagus cuniculus rabbit - (species) D	Agouti (ASIP)	Oryctolagus cuniculus rabbit - (species)	Published - Accepted by Curator
Agouti (ASIP)	Coloration (coat)	Coding, Deletion N	D	Intraspecific	Candidate Gene	Miller SM; Guthrie AJ; Harper CK (2016) Single base-pair deletion in ASIP exon 3 associated with recessive black phenotype in impala (Aepyce[...]	GP00001977	Asip Q03288	Morphology	recessive c.174delA was found in all black phenotype sequences ; premature stop codon (239–241 bp) N		D	Agouti (ASIP)		Published - Accepted by Curator
Agouti (ASIP)	Coloration (coat)	Coding, Deletion N	Camelus dromedarius Arabian camel - (species) D	Domesticated	Candidate Gene	Almathen F; Elbir H; Bahbahani H ; et al. (2018) Polymorphisms in MC1R and ASIP Genes are Associated with Coat Color Variation in the Arabian Camel. 1 Additional References Alshanbari F; Castaneda C; Juras R (2019) Comparative FISH-Mapping of MC1R, ASIP, and TYRP1 in New and Old World Camelids and Association Anal[...]	GP00001978	Asip Q03288	Morphology	1-bp deletion at position 23 resulting in frameshift N	Camelus dromedarius Arabian camel - (species)	Camelus dromedarius Arabian camel - (species) D	Agouti (ASIP)	Camelus dromedarius Arabian camel - (species)	Published - Accepted by Curator
AHR	Xenobiotic resistance (TCDD)	Coding, SNP N	Rattus norvegicus Norway rat - (species) D	Intraspecific	Linkage Mapping	Tuomisto JT; Viluksela M; Pohjanvirta R ; et al. (1999) The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resista[...] 2 Additional References Moffat ID; Roblin S; Harper PA (2007) Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: tissue expression and transac[...] Pohjanvirta R; Wong JM; Li W (1998) Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon[...]	GP00001813	Ahr P30561	Physiology	point mutation in the exon/intron 10 boundary in AHR genomic structure that leads to use of 3 alternative cryptic splice sites; potentially creating 3 alternative transcripts and 2 protein products. At the protein level the mutation leads to a total loss of either 43 or 38 amino acids (with altered sequence for the last seven amino acids in the latter case) toward the carboxyl-terminal end in the trans-activation domain of the AhR. H/W rats also harbor a point mutation in exon 10 that will cause a Val-to-Ala substitution in codon 497, but this occurs in a variable region of the AhR N	Rattus norvegicus Norway rat - (species)	Rattus norvegicus Norway rat - (species) D	AHR	Rattus norvegicus Norway rat - (species)	Published - Accepted by Curator
AHR2	Xenobiotic resistance (pollution)	Gene Loss, Deletion N	Fundulus heteroclitus mummichog - (species) D	Intraspecific	Association Mapping	Reid NM; Proestou DA; Clark BW ; et al. (2016) The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. 1 Additional References Clark BW; Matson CW; Jung D (2010) AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic kill[...]	GP00001806	Ahr P30561	Physiology	70 kb deletion that removes parts of the two genes AHR1a and AHR2a N	Fundulus heteroclitus mummichog - (species)	Fundulus heteroclitus mummichog - (species) D	AHR2	Fundulus heteroclitus mummichog - (species)	Published - Accepted by Curator
AHR2	Xenobiotic resistance (pollution)	Gene Loss, Deletion N	Fundulus heteroclitus mummichog - (species) D	Intraspecific	Association Mapping	Reid NM; Proestou DA; Clark BW ; et al. (2016) The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. 1 Additional References Clark BW; Matson CW; Jung D (2010) AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic kill[...]	GP00001807	Ahr P30561	Physiology	45 kb deletion that removes parts of the two genes AHR1a and AHR2a (from exon 5 of AHR2a to exon 4 of AHR1a) N	Fundulus heteroclitus mummichog - (species)	Fundulus heteroclitus mummichog - (species) D	AHR2	Fundulus heteroclitus mummichog - (species)	Published - Accepted by Curator
AHR2	Xenobiotic resistance (pollution)	Gene Loss, Deletion N	Fundulus heteroclitus mummichog - (species) D	Intraspecific	Association Mapping	Reid NM; Proestou DA; Clark BW ; et al. (2016) The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. 1 Additional References Clark BW; Matson CW; Jung D (2010) AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic kill[...]	GP00001808	Ahr P30561	Physiology	83 kb deletion that removes parts of the two genes AHR1a and AHR2a (from exon 11 of AHR2a to exon 6 of AHR1a) N	Fundulus heteroclitus mummichog - (species)	Fundulus heteroclitus mummichog - (species) D	AHR2	Fundulus heteroclitus mummichog - (species)	Published - Accepted by Curator
AHR2	Xenobiotic resistance (pollution; polychlorinated biphenyls; PCBs)	Coding, Deletion N	Microgadus tomcod Atlantic tomcod - (species) D	Intraspecific	Candidate Gene	Wirgin I; Roy NK; Loftus M ; et al. (2011) Mechanistic basis of resistance to PCBs in Atlantic tomcod from the Hudson River.	GP00001809	Ahr P30561	Physiology	6-bp deletion - (nts 1314 to 1319 in exon 10; TTCCTC) that resulted in a two-amino acid (Phe-Leu) deletion located 43 amino acids downstream of the amino terminal of the AHR2 ligand binding domain N	Microgadus tomcod Atlantic tomcod - (species)	Microgadus tomcod Atlantic tomcod - (species) D	AHR2	Microgadus tomcod Atlantic tomcod - (species)	Published - Accepted by Curator
AIP	Xenobiotic resistance (pollution)	Unknown, Unknown N	Fundulus heteroclitus mummichog - (species) D	Intraspecific	Association Mapping	Reid NM; Proestou DA; Clark BW ; et al. (2016) The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish.	GP00001812	Aip O08915	Physiology	exact mutation(s) unknown - very good candidate gene according to association mapping and knowledge about the physiology N	Fundulus heteroclitus mummichog - (species)	Fundulus heteroclitus mummichog - (species) D	AIP	Fundulus heteroclitus mummichog - (species)	Published - Accepted by Curator
alcohol dehydrogenase (Adh)	Xenobiotic resistance (alcohol)	Coding, Insertion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Freeth AL; Gibson JB; Wilks AV (1990) Aberrant splicing of a naturally occurring alcohol dehydrogenase null activity allele in Drosophila [...] 1 Additional References Gibson JB; Wilks AV; Agrotis A (1992) Molecular relationships between alcohol dehydrogenase null-activity alleles from natural populations[...]	GP00001990	Adh P00334	Physiology	eight extra nucleotides (in two groups of four) in the second intron commencing six bases 3' from the 5' splice site. A stop codon was also found in exon 2. S1 nuclease protection experiments have shown that the insertions in intron 2 disrupt the correct splicing of intron 2. The null allele produces a transcript approximately 100 bases longer than the normal mature adult transcript, and the amount of the null allele transcript is only about 10% of the normal level. N	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	alcohol dehydrogenase (Adh)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
alcohol dehydrogenase (Adh)	Xenobiotic resistance (alcohol)	Coding, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Gibson JB; Wilks AV; Agrotis A (1992) Molecular relationships between alcohol dehydrogenase null-activity alleles from natural populations[...]	GP00001991	Adh P00334	Physiology	438-bp deletion which removes most of exon 2. Lys to Thr substitution: ACG at the sites 1489--1491 N	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	alcohol dehydrogenase (Adh)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Allantoin permease DAL4	Nitrogen use (growth rate on allantoin)	Coding, Indel N	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001503	DAL4 Q04895	Physiology	c.1201delA a single nucleotide frameshifting insertion (deletion?) N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Allantoin permease DAL4	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ameloblastin (AMBN)	Tooth absence (no enamel production)	Gene Loss, Deletion N	Gallus gallus chicken - (species) D	Intergeneric or Higher	Candidate Gene	Sire JY; Delgado SC; Girondot M (2008) Hen's teeth with enamel cap: from dream to impossibility.	GP00001934	AMBN Q9NP70	Physiology	synteny of the corresponding region - the gene has been likely deleted from the chicken genome as a consequence of intrachromosomal rearrangements which have probably occurred in the lineage that led to the last common ancestor of modern birds N	Paleosuchus palpebrosus Cuvier's dwarf caiman - (species)	Gallus gallus chicken - (species) D	ameloblastin (AMBN)	Gallus gallus chicken - (species)	Published - Accepted by Curator
ameloblastin (AMBN)	Tooth absence (no enamel production)	Coding, Unknown N	Mysticeti baleen whales - (suborder) D	Intergeneric or Higher	Candidate Gene	Deméré TA; McGowen MR; Berta A ; et al. (2008) Morphological and molecular evidence for a stepwise evolutionary transition from teeth to baleen in [...] 1 Additional References Meredith RW; Gatesy J; Cheng J (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001938	AMBN Q9NP70	Physiology	multiple frameshift mutations N	Cetacea whales - (order)	Mysticeti baleen whales - (suborder) D	ameloblastin (AMBN)	Mysticeti baleen whales - (suborder)	Published - Accepted by Curator
amelogenin (AMEL)	Tooth absence (no enamel production)	3 Mutations: Coding N	Gallus gallus chicken - (species) D	Intergeneric or Higher	Candidate Gene	Sire JY; Delgado SC; Girondot M (2008) Hen's teeth with enamel cap: from dream to impossibility.	GP00001933	Amelx P63277	Physiology	3 mutations	Paleosuchus palpebrosus Cuvier's dwarf caiman - (species)	Gallus gallus chicken - (species) D	amelogenin (AMEL)	Gallus gallus chicken - (species)	Published - Accepted by Curator
amelogenin (AMEL)	Tooth absence (no enamel production)	Coding, Unknown N	Mysticeti baleen whales - (suborder) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Cheng J ; et al. (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001937	Amelx P63277	Physiology	J. Gatesy 2010 unpublished data cited in the main reference N	Cetacea whales - (order)	Mysticeti baleen whales - (suborder) D	amelogenin (AMEL)	Mysticeti baleen whales - (suborder)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, Deletion N	Petunia axillaris (species) D	Intraspecific	Candidate Gene	Quattrocchio F; Wing J; van der Woude K ; et al. (1999) Molecular analysis of the anthocyanin2 gene of petunia and its role in the evolution of flower color[...]	GP00000089	AN2 A4GRU8	Morphology	1bp deletion at a.a. 127; premature stop N	Petunia integrifolia (species)	Petunia axillaris (species) D	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, Insertion N	Petunia axillaris (species) D	Intraspecific	Candidate Gene	Quattrocchio F; Wing J; van der Woude K ; et al. (1999) Molecular analysis of the anthocyanin2 gene of petunia and its role in the evolution of flower color[...]	GP00000090	AN2 A4GRU8	Morphology	4bp insertion at a.a. 127; premature stop N	Petunia integrifolia (species)	Petunia axillaris (species) D	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, SNP N	Petunia axillaris (species)	Intraspecific	Candidate Gene	Quattrocchio F; Wing J; van der Woude K ; et al. (1999) Molecular analysis of the anthocyanin2 gene of petunia and its role in the evolution of flower color[...]	GP00000091	AN2 A4GRU8	Morphology	W196* N	Petunia integrifolia (species)	Petunia axillaris (species)	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, Deletion N	Petunia axillaris (species) D	Intraspecific	Candidate Gene	Hoballah ME; Gübitz T; Stuurman J ; et al. (2007) Single gene-mediated shift in pollinator attraction in Petunia.	GP00000092	AN2 A4GRU8	Morphology	1bp deletion; premature stop N	Petunia integrifolia (species)	Petunia axillaris (species) D	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, SNP N	Petunia axillaris (species)	Interspecific	Candidate Gene	Hoballah ME; Gübitz T; Stuurman J ; et al. (2007) Single gene-mediated shift in pollinator attraction in Petunia.	GP00000093	AN2 A4GRU8	Morphology	1 aa substitution; premature stop N	Petunia integrifolia (species)	Petunia axillaris (species)	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
anthocyanin2 (an2)	Coloration (flowers)	Coding, SNP N	Petunia axillaris (species)	Interspecific	Candidate Gene	Hoballah ME; Gübitz T; Stuurman J ; et al. (2007) Single gene-mediated shift in pollinator attraction in Petunia.	GP00000094	AN2 A4GRU8	Morphology	1 aa substitution; premature stop N	Petunia integrifolia (species)	Petunia axillaris (species)	anthocyanin2 (an2)	Petunia axillaris (species)	Published - Accepted by Curator
AOP2	Glucosinolate content	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Kliebenstein DJ; Lambrix VM; Reichelt M ; et al. (2001) Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dio[...] 2 Additional References Chan EK; Rowe HC; Kliebenstein DJ (2010) Understanding the evolution of defense metabolites in Arabidopsis thaliana using genome-wide associa[...] Chan EK; Rowe HC; Corwin JA (2011) Combining genome-wide association mapping and transcriptional networks to identify novel genes contr[...]	GP00000095	AOP2 Q945B5	Physiology	5bp deletion resulting in frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AOP2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
APSR	Sulfate content (shoot)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Loudet O; Saliba-Colombani V; Camilleri C ; et al. (2007) Natural variation for sulfate content in Arabidopsis thaliana is highly controlled by APR2.	GP00000100	APR2 P92981	Physiology	A399E N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	APSR	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	2 Mutations: Coding SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001872	AQP1 P29972	Physiology	2 mutations	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001873	AQP1 P29972	Physiology	aquaporin yeast 1 gene on chromosome 12 - A881 deletion renders AQY1 inactive - size of the deletion not indicated in the paper - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY1)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Bonhivers M; Carbrey JM; Gould SJ (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type st[...]	GP00001874	AQP1 P29972	Physiology	aquaporin yeast 1 gene on chromosome 12 - 955-bp deletion that removes the first 106 bp of AQY1 and its upstream region - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY1)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Linkage Mapping	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Carbrey JM; Bonhivers M; Boeke JD (2001) Aquaporins in Saccharomyces: Characterization of a second functional water channel protein.	GP00001875	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - 11-bp deletion that creates a stop codon in the middle of the AQY2 gene - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...] 1 Additional References Laizé V; Tacnet F; Ripoche P (2000) Polymorphism of Saccharomyces cerevisiae aquaporins.	GP00001876	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - deletion of nucleotide G at position 25 (G25) which creates a frameshift the AQY2 gene - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Aquaporin (AQY2)	Growth rate (environment-dependent)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Domesticated	Candidate Gene	Will JL; Kim HS; Clarke J ; et al. (2010) Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisia[...]	GP00001877	AQP1 P29972	Physiology	aquaporin yeast 2 gene on chromosome 11 - G528 deletion which creates a frameshift the AQY2 gene - tested in assays - GenBank accession numbers for AQY1 and AQY2: GQ848552-74 and GQ870433-54 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Aquaporin (AQY2)	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
arcp-1	CO2 avoidance Aggregation behavior	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Beets I; Zhang G; Fenk LA ; et al. (2019) Natural Variation in a Dendritic Scaffold Protein Remodels Experience-Dependent Plasticity by Alteri[...]	GP00002067	CELE_F34D10.6 C6KRH4	Behavior Behavior	8 bp deletion (mfP22) in the open reading frame N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	arcp-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
ARHGAP11B	Neocortex development (basal progenitor amplification)	Coding, SNP N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Florio M; Namba T; Pääbo S ; et al. (2016) A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification.	GP00001442	ARHGAP11B Q3KRB8	Morphology	c.661C>G new splice site mutation removing 55nt from exon 5 truncating a GAP domain N	Homo sapiens human - (species)	Homo sapiens human - (species) D	ARHGAP11B	Homo sapiens human - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000106	GA20OX1 Q39110	Morphology	Whole gene deletion N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000107	GA20OX1 Q39110	Morphology	-2bp at +297 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000108	GA20OX1 Q39110	Morphology	-1bp "G" at +324 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000109	GA20OX1 Q39110	Morphology	-5bp "G" at +545 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000110	GA20OX1 Q39110	Morphology	-10bp "G" at +784 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000111	GA20OX1 Q39110	Morphology	-29bp at +426 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000112	GA20OX1 Q39110	Morphology	-444bp at +985 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000113	GA20OX1 Q39110	Morphology	+1bp "G" at +256 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000114	GA20OX1 Q39110	Morphology	+7bp "G" at +961 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000115	GA20OX1 Q39110	Morphology	+1bp at +1270 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000116	GA20OX1 Q39110	Morphology	Transposon insertion at +1355 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000117	GA20OX1 Q39110	Morphology	W46* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...] 1 Additional References Xu YL; Li L; Wu K (1995) The GA5 locus of Arabidopsis thaliana encodes a multifunctional gibberellin 20-oxidase: molecular cl[...]	GP00000118	GA20OX1 Q39110	Morphology	W271* -G816A according to Fig.3 of Xu et al. 1995 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Domesticated	Linkage Mapping	Barboza L; Effgen S; Alonso-Blanco C ; et al. (2013) Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution d[...]	GP00000119	GA20OX1 Q39110	Morphology	E312* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
AtGA20ox1 (=GA5=Sd1)	Plant size (dwarfism)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Luo Y; Dong X; Yu T ; et al. (2015) A Single Nucleotide Deletion in Gibberellin20-oxidase1 Causes Alpine Dwarfism in Arabidopsis.	GP00001243	GA20OX1 Q39110	Morphology	-1bp at position 184 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	AtGA20ox1 (=GA5=Sd1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ATP4A	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001908	ATP4A P20648	Physiology	Absence of the gene in the genome sequence N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	ATP4A	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
ATP4A	Digestion (absence of stomach)	Gene Loss, Deletion N	Danio rerio zebrafish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001920	ATP4A P20648	Physiology	Absence of the gene in the genome sequence - high synteny N	Gadus morhua Atlantic cod - (species) Gasterosteus aculeatus three-spined stickleback - (species) Oreochromis niloticus Nile tilapia - (species)	Danio rerio zebrafish - (species) D	ATP4A	Danio rerio zebrafish - (species)	Published - Accepted by Curator
ATP4A	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001922	ATP4A P20648	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	ATP4A	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
ATP4A	Digestion (absence of stomach)	Gene Loss, Deletion N	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001928	ATP4A P20648	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	ATP4A	Takifugu rubripes torafugu - (species) Tetraodon nigroviridis spotted green pufferfish - (species)	Published - Accepted by Curator
ATP4B	Digestion (absence of stomach)	3 Mutations: Coding N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001909	ATP4B P51164	Physiology	3 mutations	Monodelphis domestica gray short-tailed opossum - (species) Homo sapiens human - (species)	Ornithorhynchus anatinus platypus - (species) D	ATP4B	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
ATP4B	Digestion (absence of stomach)	Gene Loss, Deletion N	Callorhinchus milii elephant shark - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001916	ATP4B P51164	Physiology	Absence of the gene in the genome sequence N	Scyliorhinus canicula smaller spotted catshark - (species)	Callorhinchus milii elephant shark - (species) D	ATP4B	Callorhinchus milii elephant shark - (species)	Published - Accepted by Curator
ATP4B	Digestion (absence of stomach)	Gene Loss, Deletion N	Danio rerio zebrafish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001921	ATP4B P51164	Physiology	Absence of the gene in the genome sequence - high synteny N	Gadus morhua Atlantic cod - (species) Gasterosteus aculeatus three-spined stickleback - (species) Oreochromis niloticus Nile tilapia - (species)	Danio rerio zebrafish - (species) D	ATP4B	Danio rerio zebrafish - (species)	Published - Accepted by Curator
ATP4B	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001923	ATP4B P51164	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	ATP4B	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
ATP4B	Digestion (absence of stomach)	Gene Loss, Deletion N	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001929	ATP4B P51164	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	ATP4B	Takifugu rubripes torafugu - (species) Tetraodon nigroviridis spotted green pufferfish - (species)	Published - Accepted by Curator
B2	Coloration (bulb)	Cis-regulatory, Insertion N	Allium cepa onion - (species) D	Domesticated	Linkage Mapping	Jo C; Kim S (2019) Transposition of a non-autonomous DNA transposon in the gene coding for a bHLH transcription factor [...]	GP00002058		Morphology	577-bp insertion of a transposable element named AcWHITE in the 5′ upstream region of the white allele of B2. A 8-bp target site duplication (GTTATA AC) and a 7-bp terminal inverted repeat (CAAGGTT) were identified at both ends of this insertion - no SNP detected in the coding region N	Allium cepa onion - (species)	Allium cepa onion - (species) D	B2	Allium cepa onion - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Deletion N	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Bradbury LM; Fitzgerald TL; Henry RJ ; et al. (2005) The gene for fragrance in rice. 1 Additional References Kovach MJ; Calingacion MN; Fitzgerald MA (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00000134	BADH2 Q84LK3	Physiology	8bp deletion resulting in premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species)	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Shi Weiwei; Yang Yi; Chen Saihua ; et al. (2008 ) Discovery of a new fragrance allele and the development of functional markers for the breeding of fr[...] 1 Additional References Kovach MJ; Calingacion MN; Fitzgerald MA (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001772	BADH2 Q84LK3	Physiology	7-bp deletion in exon 2 resulting in premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001773	BADH2 Q84LK3	Physiology	2-bp deletion in exon 1 resulting in premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Insertion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001774	BADH2 Q84LK3	Physiology	insertion of 1 bp (T) in exon 10 N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001775	BADH2 Q84LK3	Physiology	G>T substitution in exon 10 - need to check the sequence to check if this mutation is nonsense or nonsynonymous N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001776	BADH2 Q84LK3	Physiology	G>T substitution in exon 14 - need to check the sequence to check if this mutation is nonsense or nonsynonymous N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001777	BADH2 Q84LK3	Physiology	C>T substitution in exon 13 - need to check the sequence to check if this mutation is nonsense or nonsynonymous N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001778	BADH2 Q84LK3	Physiology	1-bp deletion in exon 10 - causes a frameshift N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Insertion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001779	BADH2 Q84LK3	Physiology	1-bp insertion (G) in exon 14 N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BADH2	Fragrance	Coding, Insertion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Kovach MJ; Calingacion MN; Fitzgerald MA ; et al. (2009) The origin and evolution of fragrance in rice (Oryza sativa L.).	GP00001780	BADH2 Q84LK3	Physiology	3-bp insertion (TAT) in exon 13 - causes a frameshift N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	BADH2	Oryza sativa rice - (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Carotenoid content	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Berry SD; Davis SR; Beattie EM ; et al. (2009) Mutation in bovine beta-carotene oxygenase 2 affects milk color. 1 Additional References Tian R; Pitchford WS; Morris CA (2010) Genetic variation in the beta, beta-carotene-9', 10'-dioxygenase gene and association with fat colou[...]	GP00000138	BCO2 Q9BYV7	Physiology	Substitution creating premature Stop (codon 79) N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	BCO2 = beta-carotene oxygenase 2	Bos taurus cattle - (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Carotenoid content	Coding, SNP N	Ovis aries sheep - (species)	Domesticated	Candidate Gene	Våge DI; Boman IA (2010) A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumula[...]	GP00000140	BCO2 Q9BYV7	Physiology	Substitution creating premature Stop (codon 66) N	Ovis aries sheep - (species)	Ovis aries sheep - (species)	BCO2 = beta-carotene oxygenase 2	Ovis aries sheep - (species)	Published - Accepted by Curator
BCO2 = beta-carotene oxygenase 2	Carotenoid content (bill, legs)	Coding, SNP N	Serinus canaria common canary - (species) D	Domesticated	Association Mapping	Gazda Malgorzata A.; Toomey Matthew B.; Araujo Pedro M. ; et al. (2019/01/01 ) Genetic Basis Of De Novo Appearance Of Carotenoid Ornamentation In Bare-Parts Of Canaries	GP00002039	BCO2 Q9BYV7	Morphology	point mutation at nucleotide position 837,806 that is predicted to be a nonsynonymous mutation in the exon 9 of the BCO2 gene. This variant results in the substitution of a histidine for an arginine at residue 413 of the protein (R413H) . In silico analysis suggests that the R413H could cause structural distortion of the protein and lead to a possible loss of activity. In vitro assays with the urucum BCO2 variant show that the enzyme activity is lost. N	Serinus canaria common canary - (species)	Serinus canaria common canary - (species) D	BCO2 = beta-carotene oxygenase 2	Serinus canaria common canary - (species)	Published - Accepted by Curator
Beta-glucosidase6 (BGLU6)	Resistance to UV irradiation (flavonol glycosylation)	Coding, SNP N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Ishihara H; Tohge T; Viehöver P ; et al. (2016) Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltran[...] 1 Additional References Keurentjes JJ; Fu J; de Vos CH (2006) The genetics of plant metabolism.	GP00001263	BGLU6 Q682B4	Physiology	T-> A of a splice site at position 168 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Beta-glucosidase6 (BGLU6)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Beta-glucosidase6 (BGLU6)	Resistance to UV irradiation (flavonol glycosylation)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Ishihara H; Tohge T; Viehöver P ; et al. (2016) Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltran[...] 1 Additional References Keurentjes JJ; Fu J; de Vos CH (2006) The genetics of plant metabolism.	GP00001264	BGLU6 Q682B4	Physiology	1-bp deletion of a splice site at position 395 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Beta-glucosidase6 (BGLU6)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Beta-glucosidase6 (BGLU6)	Resistance to UV irradiation (flavonol glycosylation)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Ishihara H; Tohge T; Viehöver P ; et al. (2016) Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltran[...] 1 Additional References Keurentjes JJ; Fu J; de Vos CH (2006) The genetics of plant metabolism.	GP00001265	BGLU6 Q682B4	Physiology	GAG to stop codon TAG at position 913 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Beta-glucosidase6 (BGLU6)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Beta-glucosidase6 (BGLU6)	Resistance to UV irradiation (flavonol glycosylation)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Ishihara H; Tohge T; Viehöver P ; et al. (2016) Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltran[...] 1 Additional References Keurentjes JJ; Fu J; de Vos CH (2006) The genetics of plant metabolism.	GP00001266	BGLU6 Q682B4	Physiology	A deletion of one nucleotide in the seventh exon (BGLU6 CDS position 678) results in a premature stop codon in the accessions Bor-4, Se-0, Uod-1, and Zdr-1. premature stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Beta-glucosidase6 (BGLU6)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Beta-glucosidase6 (BGLU6)	Resistance to UV irradiation (flavonol glycosylation)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Ishihara H; Tohge T; Viehöver P ; et al. (2016) Natural variation in flavonol accumulation in Arabidopsis is determined by the flavonol glucosyltran[...] 1 Additional References Keurentjes JJ; Fu J; de Vos CH (2006) The genetics of plant metabolism.	GP00001267	BGLU6 Q682B4	Physiology	GAG to stop codon TAG at position 1138 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Beta-glucosidase6 (BGLU6)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001830	TUB2 P02557	Physiology	A185P - missense_variant_c.553G>C_3539974 – A185P N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001832	TUB2 P02557	Physiology	stop_gained_HIGH_c.1267C>T_3538394 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Insertion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001833	TUB2 P02557	Physiology	Trans_3538426_3538832 – insertion of a transposable element = a cut and paste DNA transposon Tc5B - which is part of the TcMar-Tc4 transposon superfamily– 406bp of the reference sequence seem to be disrupted- Steffen Hahnel comment : Since we didn't re-amplify the insertion by PCR; we don't know its exact location; sequence and size. Its identification is only based on the illumina reads of genome sequencing of JU3125. N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001834	TUB2 P02557	Physiology	missense_variant_MODERATE_c.1210G>A_3538451 – D404N N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001835	TUB2 P02557	Physiology	Del_3539006_3539808 – 802bp deletion of coding exon 4 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001836	TUB2 P02557	Physiology	stop_gained_HIGH_c.1135A>T_3539335 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001837	TUB2 P02557	Physiology	stop_gained_HIGH_c.1112C>A_3539358 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001838	TUB2 P02557	Physiology	Del_3539375_3539378 – 3bp deletion in coding exon 4 predicted to cause a frameshift in the ben-1 open reading frame N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001839	TUB2 P02557	Physiology	Del_3539470_3539471 – 1bp deletion in coding exon 4 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001840	TUB2 P02557	Physiology	Del_3539507_3539514 – 7bp deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001841	TUB2 P02557	Physiology	Del_3539559_3539745 – 186 bp deletion in coding exon 4 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Insertion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001842	TUB2 P02557	Physiology	Ins_3539575_3539576 – Steffen Hahnel comment: 1 bp insertion in coding exon 4 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001843	TUB2 P02557	Physiology	missense_variant_MODERATE_c.771G>A_3539699 – M257I N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001844	TUB2 P02557	Physiology	Del_3539746_3539908 – 162 bp deletion in exon3-4 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001845	TUB2 P02557	Physiology	stop_gained_HIGH_c.549C>A_3539978 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001846	TUB2 P02557	Physiology	missense_variant_MODERATE_c.434C>T_3540145 – S145F N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001847	TUB2 P02557	Physiology	missense_variant_MODERATE_c.392A>T_3540187 – comment from Steffen Hahnel: The amino acid change is Q131L. This strain was excluded from the original screen because it was slow growing. We re-phenotyped it later (see Sup Fig. 9) N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001848	TUB2 P02557	Physiology	Del_3540300_3540301 – 1bp deletion in coding exon 2 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Inversion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001849	TUB2 P02557	Physiology	Inv_3540316_3543965 – 3649bp inversion – the text indicates that there is “a 1kb inversion that spans exon 1 and the promoter region” but the nucleotide numbers in the supplemental table indicates that 3.6kb are disrupted. Steffen Hahnel comment: we don't know the exact size of this large structural variation. I estimated conservatively from the BAM files that a region of 3649 bp is messed up in this strain compared to wildtype including one or more inversions. The largest inversion is around 1 kb. If one wants to be sure about size and location you would need to amplify this region by PCR N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Unknown N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001850	TUB2 P02557	Physiology	Del_3540369_3540369 and missense_variant_c.206A>G_3540373 E69G - the amino acid substitution (E69G) co-occurs with a deletion in exon 2 that is predicted to cause a frameshift in the ben-1 open reading frame – not sure which mutation or both are responsible for the phenotype N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001851	TUB2 P02557	Physiology	Del_3540407_3540408 – 1bp deletion in coding exon 2 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001852	TUB2 P02557	Physiology	Del_3540970_3544000 – 3030bp deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001853	TUB2 P02557	Physiology	Del_3541317_3541856 – 539 bp deletion in first coding exon N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001854	TUB2 P02557	Physiology	splice_donor_variant and intron_variant – first coding exon – c.166+1G>A_3541427 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001855	TUB2 P02557	Physiology	stop_gained_HIGH_c.153T>G_3541441 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001856	TUB2 P02557	Physiology	Del_3541499_3541502 – 3bp deletion in first coding exon N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
beta-tubulin (ben-1)	Xenobiotic resistance (benzimidazole)	Coding, Insertion N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Hahnel SR; Zdraljevic S; Rodriguez BC ; et al. (2018) Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resist[...]	GP00001857	TUB2 P02557	Physiology	Ins_3541547_3541548 – 1 bp insertion in first coding exon N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	beta-tubulin (ben-1)	Caenorhabditis elegans (species)	Published - Accepted by Curator
Bh4	Coloration (seed hull)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Zhu BF; Si L; Wang Z ; et al. (2011) Genetic control of a transition from black to straw-white seed hull in rice domestication. 1 Additional References Huang X; Kurata N; Wei X (2012) A map of rice genome variation reveals the origin of cultivated rice.	GP00000143	Bh4 A0A0H3ZGK8	Morphology	22-bp deletion N	Oryza rufipogon (species)	Oryza sativa rice - (species) D	Bh4	Oryza sativa rice - (species)	Published - Accepted by Curator
bHLH2	Coloration (flower; seed)	Coding, Insertion N	Ipomoea purpurea common morning-glory - (species) D	Domesticated	Candidate Gene	Park KI; Ishikawa N; Morita Y ; et al. (2007) A bHLH regulatory gene in the common morning glory, Ipomoea purpurea, controls anthocyanin biosynthe[...]	GP00002078	BHLH2 Q9CAD0	Morphology	two copies of 3.9-kb Tip100 integrated into bHLH2 exon 7 and intron 2 N	Ipomoea purpurea common morning-glory - (species)	Ipomoea purpurea common morning-glory - (species) D	bHLH2	Ipomoea purpurea common morning-glory - (species)	Published - Accepted by Curator
bHLH2	Coloration (flower; seed)	Coding, Insertion N	Ipomoea purpurea common morning-glory - (species) D	Domesticated	Candidate Gene	Park KI; Ishikawa N; Morita Y ; et al. (2007) A bHLH regulatory gene in the common morning glory, Ipomoea purpurea, controls anthocyanin biosynthe[...]	GP00002085	BHLH2 Q9CAD0	Morphology	only one copy of Tip100 in exon 7 and no apparent footprint of Tip100 in intron 2 N	Ipomoea purpurea common morning-glory - (species)	Ipomoea purpurea common morning-glory - (species) D	bHLH2	Ipomoea purpurea common morning-glory - (species)	Published - Accepted by Curator
bHLH2	Coloration (flower; seed)	Coding, Insertion N	Ipomoea purpurea common morning-glory - (species) D	Domesticated	Candidate Gene	Park KI; Ishikawa N; Morita Y ; et al. (2007) A bHLH regulatory gene in the common morning glory, Ipomoea purpurea, controls anthocyanin biosynthe[...]	GP00002086	BHLH2 Q9CAD0	Morphology	insertion of 838 bp IpMu1 in exon 2 N	Ipomoea purpurea common morning-glory - (species)	Ipomoea purpurea common morning-glory - (species) D	bHLH2	Ipomoea purpurea common morning-glory - (species)	Published - Accepted by Curator
bHLH2	Coloration (flowers; seeds)	Coding, Insertion N	Ipomoea tricolor (species) D	Domesticated	Candidate Gene	Park KI; Choi JD; Hoshino A ; et al. (2004) An intragenic tandem duplication in a transcriptional regulatory gene for anthocyanin biosynthesis c[...]	GP00002091	BHLH2 Q9CAD0	Morphology	intragenic tandem duplication of 3.3 kbp of the bHLH2 gene. Each of the tandem repeats is flanked by a 3-bp sequence AAT; indicating that the 3-bp microhomology is used to generate the tandem duplication. The transcripts in the pale-blue flower buds of the mutant contain an internal 583-bp tandem duplication that results in the production of a truncated polypeptide lacking the bHLH domain. The mRNA accumulation of most of the structural genes encoding enzymes for anthocyanin biosynthesis in the flower buds of the mutant was significantly reduced. The transcripts identical to the wild-type mRNAs for the transcriptional activator were present abundantly in blue spots of the variegated flowers whereas the transcripts containing the 583-bp tandem duplication were predominant in the pale-blue background of the same flowers. The flower and seed variegations studied here are likely to be caused by somatic homologous recombination between an intragenic tandem duplication in the gene encoding a bHLH transcriptional activator for anthocyanin biosynthesis. N	Ipomoea tricolor (species)	Ipomoea tricolor (species) D	bHLH2	Ipomoea tricolor (species)	Published - Accepted by Curator
bHLH2	Coloration (flowers)	Coding, Insertion N	Petunia axillaris (species) D	Domesticated	Candidate Gene	Spelt C; Quattrocchio F; Mol J ; et al. (2002) ANTHOCYANIN1 of petunia controls pigment synthesis, vacuolar pH, and seed coat development by geneti[...]	GP00002092	BHLH2 Q9CAD0	Morphology	insertion of a dTph1 transposon in the AN1 gene N	Petunia axillaris (species)	Petunia axillaris (species) D	bHLH2	Petunia axillaris (species)	Published - Accepted by Curator
Bm-iAANAT	Coloration (larva)	Coding, Deletion N	Bombyx mori domestic silkworm - (species) D	Domesticated	Linkage Mapping	Zhan S; Guo Q; Li M ; et al. (2010) Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. 1 Additional References Dai FY; Qiao L; Tong XL (2010) Mutations of an arylalkylamine-N-acetyltransferase, Bm-iAANAT, are responsible for silkworm melanism[...]	GP00000145	Aanat D6MKR2	Morphology	126-bp deletion overlapping with end of exon 4 and resulting in misplicing N	Bombyx mori domestic silkworm - (species)	Bombyx mori domestic silkworm - (species) D	Bm-iAANAT	Bombyx mori domestic silkworm - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001488	BMH1 P29311	Physiology	C>G p.Y216* heterozygous. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001489	BMH1 P29311	Physiology	G>T p.E214*. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001490	BMH1 P29311	Physiology	A>T p.K217* (2 times independently). Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001492	BMH1 P29311	Physiology	T>G p.L230* heterozygous. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMH1	Growth rate (time to diauxic shift)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001494	BMH1 P29311	Physiology	G>T p.E214*. Truncated protein will lack the final helix of the C-terminus as well as a glutamine repeat known to be involved in protein/protein interactions N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	BMH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
BMP15	Fertility (increased ovulation rate)	Coding, SNP N	Ovis aries sheep - (species)	Domesticated	Linkage Mapping	Galloway SM; McNatty KP; Cambridge LM ; et al. (2000) Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and inferti[...]	GP00000147	Bmp15 Q9Z0L4	Physiology	Q23*; CAG - > TAG N	Ovis aries sheep - (species)	Ovis aries sheep - (species)	BMP15	Ovis aries sheep - (species)	Published - Accepted by Curator
BNA1	Nicotinid acid metabolism	Gene Loss, Deletion N	[Candida] glabrata (species) D	Interspecific	Candidate Gene	Domergue R; Castaño I; De Las Peñas A ; et al. (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.	GP00001878	BNA1 P47096	Physiology	Size of the deletion not mentioned in the paper N	Candida albicans (species)	[Candida] glabrata (species) D	BNA1	[Candida] glabrata (species)	Published - Accepted by Curator
BNA2	Nicotinid acid metabolism	Gene Loss, Deletion N	[Candida] glabrata (species) D	Interspecific	Candidate Gene	Domergue R; Castaño I; De Las Peñas A ; et al. (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.	GP00001879	P47125	Physiology	Size of the deletion not mentioned in the paper N	Candida albicans (species)	[Candida] glabrata (species) D	BNA2	[Candida] glabrata (species)	Published - Accepted by Curator
BNA4	Nicotinid acid metabolism	Gene Loss, Deletion N	[Candida] glabrata (species) D	Interspecific	Candidate Gene	Domergue R; Castaño I; De Las Peñas A ; et al. (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.	GP00001880	BNA4 P38169	Physiology	Size of the deletion not mentioned in the paper N	Candida albicans (species)	[Candida] glabrata (species) D	BNA4	[Candida] glabrata (species)	Published - Accepted by Curator
BNA5	Nicotinid acid metabolism	Gene Loss, Deletion N	[Candida] glabrata (species) D	Interspecific	Candidate Gene	Domergue R; Castaño I; De Las Peñas A ; et al. (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.	GP00001881	BNA5 Q05979	Physiology	Size of the deletion not mentioned in the paper N	Candida albicans (species)	[Candida] glabrata (species) D	BNA5	[Candida] glabrata (species)	Published - Accepted by Curator
BNA6	Nicotinid acid metabolism	Gene Loss, Deletion N	[Candida] glabrata (species) D	Interspecific	Candidate Gene	Domergue R; Castaño I; De Las Peñas A ; et al. (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.	GP00001882	BNA6 P43619	Physiology	Size of the deletion not mentioned in the paper N	Candida albicans (species)	[Candida] glabrata (species) D	BNA6	[Candida] glabrata (species)	Published - Accepted by Curator
Brevis radix (BRX)	Root size (shorter)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Mouchel CF; Briggs GC; Hardtke CS (2004) Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel regulator of cell prolifer[...]	GP00000157	BRX Q17TI5	Morphology	premature stop codon in exon 4; TGG>TGA; truncated protein missing approximately two-thirds of the C terminus N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Brevis radix (BRX)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Brevis radix (BRX)	pH tolerance (acidic soil)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Gujas B; Alonso-Blanco C; Hardtke CS (2012) Natural Arabidopsis brx loss-of-function alleles confer root adaptation to acidic soil.	GP00001236	BRX Q17TI5	Physiology	K188* (stop codon) N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Brevis radix (BRX)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
btr1	Seed shattering (grain dispersal ; retention)	Coding, Deletion N	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies) D	Domesticated	Linkage Mapping	Pourkheirandish M; Hensel G; Kilian B ; et al. (2015) Evolution of the Grain Dispersal System in Barley.	GP00001445	BTR1 A0A0K1RJT0	Physiology	1bp deletion at position 202 inducing a frameshift N	Hordeum vulgare (species)	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies) D	btr1	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies)	Published - Accepted by Curator
BTR1- Cadherin-like protein	Xenobiotic resistance (insecticide; Bt Cry1Ac)	Coding, Unknown N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Linkage Mapping	Xu X; Yu L; Wu Y (2005) Disruption of a cadherin gene associated with resistance to Cry1Ac {delta}-endotoxin of Bacillus thu[...]	GP00000160	BtR Q19KJ3	Physiology	premature stop codon in exon 4; truncated protein missing approximately two-thirds of the C terminus N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	BTR1- Cadherin-like protein	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
BTR1- Cadherin-like protein	Xenobiotic resistance (insecticide)	Coding, Insertion N	Heliothis virescens tobacco budworm - (species) D	Intraspecific	Linkage Mapping	Gahan LJ; Gould F; Heckel DG (2001) Identification of a gene associated with Bt resistance in Heliothis virescens.	GP00000161	BtR Q19KJ3	Physiology	Insertion of retrotransposon N	Heliothis virescens tobacco budworm - (species)	Heliothis virescens tobacco budworm - (species) D	BTR1- Cadherin-like protein	Heliothis virescens tobacco budworm - (species)	Published - Accepted by Curator
BTR1- Cadherin-like protein	Xenobiotic resistance (insecticide)	Coding, Deletion N	Pectinophora gossypiella pink bollworm - (species) D	Intraspecific	Linkage Mapping	Morin S; Biggs RW; Sisterson MS ; et al. (2003) Three cadherin alleles associated with resistance to Bacillus thuringiensis in pink bollworm. 1 Additional References Zhang H; Tian W; Zhao J (2012) Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China.	GP00000162	BtR Q19KJ3	Physiology	126bp in-frame deletion N	Pectinophora gossypiella pink bollworm - (species)	Pectinophora gossypiella pink bollworm - (species) D	BTR1- Cadherin-like protein	Pectinophora gossypiella pink bollworm - (species)	Published - Accepted by Curator
BTR1- Cadherin-like protein	Xenobiotic resistance (insecticide)	Coding, Deletion N	Pectinophora gossypiella pink bollworm - (species) D	Intraspecific	Linkage Mapping	Morin S; Biggs RW; Sisterson MS ; et al. (2003) Three cadherin alleles associated with resistance to Bacillus thuringiensis in pink bollworm. 1 Additional References Zhang H; Tian W; Zhao J (2012) Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China.	GP00000163	BtR Q19KJ3	Physiology	202bp deletion N	Pectinophora gossypiella pink bollworm - (species)	Pectinophora gossypiella pink bollworm - (species) D	BTR1- Cadherin-like protein	Pectinophora gossypiella pink bollworm - (species)	Published - Accepted by Curator
btr2	Seed shattering (grain dispersal ; retention)	Coding, Deletion N	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies) D	Domesticated	Linkage Mapping	Pourkheirandish M; Hensel G; Kilian B ; et al. (2015) Evolution of the Grain Dispersal System in Barley.	GP00001446	BTR2 A0A0K1RKV9	Physiology	11bp deletion at position 254-264 creating a frameshift N	Hordeum vulgare (species)	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies) D	btr2	Hordeum vulgare subsp. vulgare domesticated barley - (subspecies)	Published - Accepted by Curator
BvCPSF73-Ia	Bolting time	Coding, Deletion N	Beta vulgaris (species) D	Intraspecific	Linkage Mapping	Tränkner C; Lemnian IM; Emrani N ; et al. (2016) A Detailed Analysis of the BR Locus Suggests a New Mechanism for Bolting after Winter in Sugar Beet [...]	GP00001411	CPSF73-I Q9C952	Physiology	2bp deletion causing a frameshift resulting in a two third truncated protein N	Beta vulgaris (species)	Beta vulgaris (species) D	BvCPSF73-Ia	Beta vulgaris (species)	Published - Accepted by Curator
cadherin	Xenobiotic resistance (insecticide; Bt Cry1Ac)	Coding, SNP N	Helicoverpa punctigera (species) D	Intraspecific	Candidate Gene	Walsh T; James B; Chakroun M ; et al. (2018) Isolating, characterising and identifying a Cry1Ac resistance mutation in field populations of Helic[...]	GP00002055	BtR Q19KJ3	Physiology	splice site GT mutated in GA so that splicing does not occur correctly and a 58 bp insertion is found in the cDNA sequence of the cadherin gene. This insertion disrupts the coding sequence in cadherin domain 9 causing a downstream frameshift and a premature stop codon for the rest of the protein. This would result in a truncated protein of 1243 amino acids without the putative binding domain; the membrane anchoring domain; presumably retained inside the cell and not exposed to the Cry1Ac; or alternatively; exported into the gut where it would be degraded N	Helicoverpa punctigera (species)	Helicoverpa punctigera (species) D	cadherin	Helicoverpa punctigera (species)	Published - Accepted by Curator
cathepsin E	Digestion (absence of stomach)	2 Mutations: Coding N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001910	CTSE P14091	Physiology	2 mutations	Monodelphis domestica gray short-tailed opossum - (species) Homo sapiens human - (species)	Ornithorhynchus anatinus platypus - (species) D	cathepsin E	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
Cauliflower (BoCAL)	Inflorescence morphology	Coding, SNP N	Brassica oleracea var. botrytis (varietas) D	Domesticated	Candidate Gene	Kempin SA; Savidge B; Yanofsky MF (1995) Molecular basis of the cauliflower phenotype in Arabidopsis. 1 Additional References Purugganan MD; Boyles AL; Suddith JI (2000) Variation and selection at the CAULIFLOWER floral homeotic gene accompanying the evolution of domest[...]	GP00000173	CAL Q39081	Morphology	GAG>TAG; E151*; protein truncated after only 150 of the 255 amino acids of the wild-type protein N	Brassica oleracea wild cabbage - (species)	Brassica oleracea var. botrytis (varietas) D	Cauliflower (BoCAL)	Brassica oleracea var. botrytis (varietas)	Published - Accepted by Curator
Cf-2.1 and Cf-2.2	Pathogen resistance (leaf mold fungus ; root parasitic nematode)	Gene Loss, Deletion N	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Dixon MS; Jones DA; Keddie JS ; et al. (1996) The tomato Cf-2 disease resistance locus comprises two functional genes encoding leucine-rich repeat[...] 2 Additional References Dixon MS; Hatzixanthis K; Jones DA (1998) The tomato Cf-5 disease resistance gene and six homologs show pronounced allelic variation in leucin[...] Lozano-Torres JL; Wilbers RH; Gawronski P (2012) Dual disease resistance mediated by the immune receptor Cf-2 in tomato requires a common virulence t[...]	GP00000180	Q41398	Physiology	loss of the two genes Cf-2.1 and Cf-2.2 (see Dixon et al. 1998) in cultivated tomato - resistance re-acquired from related species N	Solanum pimpinellifolium (species)	Solanum lycopersicum tomato - (species) D	Cf-2.1 and Cf-2.2	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
Cinnamate-CoA ligase 1 (CNL1)	Fragrance	3 Mutations: N	Petunia exserta (species) D	Interspecific	Linkage Mapping	Amrad A; Moser M; Mandel T ; et al. (2016) Gain and Loss of Floral Scent Production through Changes in Structural Genes during Pollinator-Media[...]	GP00001391	CNL A0A172W603	Physiology	3 mutations	Petunia axillaris (species)	Petunia exserta (species) D	Cinnamate-CoA ligase 1 (CNL1)	Petunia exserta (species)	Published - Accepted by Curator
Cinnamate-CoA ligase 1 (CNL1)	Fragrance	Coding, SNP N	Capsella rubella (species) D	Interspecific	Linkage Mapping	Sas C; Müller F; Kappel C ; et al. (2016) Repeated Inactivation of the First Committed Enzyme Underlies the Loss of Benzaldehyde Emission afte[...]	GP00001767	CNL A0A172W603	Physiology	serine-to-arginine exchange at position 453 (T-to-A nucleotide exchange at genomic position 7 539 424) - this mutation is located immediately next to highly conserved amino acids predicted to be involved in adenosine monophosphate and coenzyme A binding; it involves two biochemically very dissimilar amino acids; and the serine at this position is conserved N	Capsella grandiflora (species)	Capsella rubella (species) D	Cinnamate-CoA ligase 1 (CNL1)	Capsella rubella (species)	Published - Accepted by Curator
Cinnamate-CoA ligase 1 (CNL1)	Fragrance	Coding, Deletion N	Capsella rubella (species) D	Interspecific	Linkage Mapping	Sas C; Müller F; Kappel C ; et al. (2016) Repeated Inactivation of the First Committed Enzyme Underlies the Loss of Benzaldehyde Emission afte[...]	GP00001768	CNL A0A172W603	Physiology	a 4 bp deletion resulting in a frameshift 795 bp downstream of the start codon and causing a premature stop codon N	Capsella grandiflora (species)	Capsella rubella (species) D	Cinnamate-CoA ligase 1 (CNL1)	Capsella rubella (species)	Published - Accepted by Curator
CINNAMOYL CO-A REDUCTASE 1	Fiber content	Coding, Unknown N	Brassica napus rape - (species)	Domesticated	Linkage Mapping	Liu L; Stein A; Wittkop B ; et al. (2012) A knockout mutation in the lignin biosynthesis gene CCR1 explains a major QTL for acid detergent lig[...]	GP00000186	CCR1 Q9S9N9	Physiology	Frameshift mutation in exon1 N	Brassica napus rape - (species)	Brassica napus rape - (species)	CINNAMOYL CO-A REDUCTASE 1	Brassica napus rape - (species)	Published - Accepted by Curator
CS	Plant secondary metabolite (pungency)	Cis-regulatory, Deletion N	Capsicum annuum (species) D	Domesticated	Candidate Gene	Kim S; Park M; Yeom SI ; et al. (2014) Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum speci[...] 1 Additional References Stewart C; Kang BC; Liu K (2005) The Pun1 gene for pungency in pepper encodes a putative acyltransferase.	GP00001447	csy1 Q09UW1	Physiology	Large 2.5 kb deletion spanning 1.8 kb of the putative promoter and 0.7 kb of the first exon was observed in the C. annuum Bellpeppers N	Capsicum frutescens (species)	Capsicum annuum (species) D	CS	Capsicum annuum (species)	Published - Accepted by Curator
CYC8	Salt tolerance (experimental evolution)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Anderson JB; Funt J; Thompson DA ; et al. (2010) Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populat[...] 1 Additional References Parreiras LS; Kohn LM; Anderson JB (2011) Cellular effects and epistasis among three determinants of adaptation in experimental populations of[...]	GP00000195	CYC8 P14922	Physiology	1bp substitution resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	CYC8	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
CYP(T)	Flower morphology (style length)	Coding, Insertion N	Primula vulgaris (species) D	Intraspecific	Linkage Mapping	Li J; Cocker JM; Wright J ; et al. (2016) Genetic architecture and evolution of the S locus supergene in Primula vulgaris.	GP00001394	CYP734A1 O48786	Morphology	single base insertion in exon 2 introduces a disruptive premature stop codon N	Primula vulgaris (species)	Primula vulgaris (species) D	CYP(T)	Primula vulgaris (species)	Published - Accepted by Curator
CYP2J19	Coloration (red vs yellow beak)	Gene Loss, Deletion N	Taeniopygia guttata zebra finch - (species) D	Domesticated	Linkage Mapping	Mundy NI; Stapley J; Bennison C ; et al. (2016) Red Carotenoid Coloration in the Zebra Finch Is Controlled by a Cytochrome P450 Gene Cluster.	GP00000202	CYP2J2 P51589	Morphology	13kb deletion including complete loss of the CYP2J19A copy and cis-regulatory effects on CYP2J19B N	Taeniopygia guttata zebra finch - (species)	Taeniopygia guttata zebra finch - (species) D	CYP2J19	Taeniopygia guttata zebra finch - (species)	Published - Accepted by Curator
CYP76AD1	Coloration	Coding, Insertion N	Beta vulgaris (species) D	Domesticated	Linkage Mapping	Hatlestad GJ; Sunnadeniya RM; Akhavan NA ; et al. (2012) The beet R locus encodes a new cytochrome P450 required for red betalain production.	GP00000210	CYP76AD1 I3PFJ5	Morphology	5bp insertion resulting in frameshift N	Beta vulgaris (species)	Beta vulgaris (species) D	CYP76AD1	Beta vulgaris (species)	Published - Accepted by Curator
CYP79D15	Toxicity levels (cyanogenic glucoside)	Gene Loss, Deletion N	Trifolium repens white clover - (species) D	Intraspecific	Linkage Mapping	Olsen KM; Hsu SC; Small LL (2008) Evidence on the molecular basis of the Ac/ac adaptive cyanogenesis polymorphism in white clover (Tri[...] 1 Additional References Olsen KM; Kooyers NJ; Small LL (2013) Recurrent gene deletions and the evolution of adaptive cyanogenesis polymorphisms in white clover (T[...]	GP00000211	CYP79D15 B2Y2T9	Physiology	Gene deletion N	Trifolium repens white clover - (species)	Trifolium repens white clover - (species) D	CYP79D15	Trifolium repens white clover - (species)	Published - Accepted by Curator
DCAR-032551	Carotenoid content	Coding, Insertion N	Daucus carota carrot - (species) D	Domesticated	Linkage Mapping	Iorizzo M; Ellison S; Senalik D ; et al. (2016) A high-quality carrot genome assembly provides new insights into carotenoid accumulation and asterid[...]	GP00001568	DCAR_032551 A0A162A3G8	Morphology	A 212-nt insertion in exon 2 that creates a frameshift mutation N	Daucus carota carrot - (species)	Daucus carota carrot - (species) D	DCAR-032551	Daucus carota carrot - (species)	Published - Accepted by Curator
DEEPER ROOTING 1	Drought tolerance Root growth	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Uga Y; Sugimoto K; Ogawa S ; et al. (2013) Control of root system architecture by DEEPER ROOTING 1 increases rice yield under drought condition[...]	GP00000215	Dro1 Q69P88	Physiology Morphology	1bp deletion within exon 4 N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	DEEPER ROOTING 1	Oryza sativa rice - (species)	Published - Accepted by Curator
Delta-1-pyrroline-5-carboxylate synthase A	Drought response (drought-induced proline accumulation)	2 Mutations: Coding	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Kesari R; Lasky JR; Villamor JG ; et al. (2012) Intron-mediated alternative splicing of Arabidopsis P5CS1 and its association with natural variation[...]	GP00001280	P5CSA P54887	Physiology	2 mutations	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Delta-1-pyrroline-5-carboxylate synthase A	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
dentin sialophosphoprotein (DSPP)	Tooth absence (no enamel production)	Coding, Deletion N	Gallus gallus chicken - (species) D	Intergeneric or Higher	Candidate Gene	Sire JY; Delgado SC; Girondot M (2008) Hen's teeth with enamel cap: from dream to impossibility.	GP00001936	DSPP Q9NZW4	Physiology	synteny of the corresponding region - only the N-terminal region of DSPP is present in the genome - 1-bp deletion in exon one leading to a reading frame shift were this sequence to be translated N	Paleosuchus palpebrosus Cuvier's dwarf caiman - (species)	Gallus gallus chicken - (species) D	dentin sialophosphoprotein (DSPP)	Gallus gallus chicken - (species)	Published - Accepted by Curator
DEP1	Grain yield	Coding, Indel N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Huang X; Qian Q; Liu Z ; et al. (2009) Natural variation at the DEP1 locus enhances grain yield in rice.	GP00000218	P0046G12.12-1 Q67UU9	Morphology	replacement of a 637bp stretch of the middle of exon5 by a 12-bp sequence creating a premature stop codon and consequently a loss of 230 residues from the C-terminus N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	DEP1	Oryza sativa rice - (species)	Published - Accepted by Curator
Dihydroflavonol 4 reductase (MlDfr)	Coloration (flower)	Coding, Insertion N	Erythranthe lewisii (species) D	Intraspecific	Candidate Gene	Wu CA; Streisfeld MA; Nutter LI ; et al. (2013) The genetic basis of a rare flower color polymorphism in Mimulus lewisii provides insight into the r[...]	GP00001457	DFRA P51102	Morphology	A 2 nt (TG) insertion at position 265 causing a frameshift and a greatly truncated protein of 106 aa only about one-fourth of its functional length N	Erythranthe lewisii (species)	Erythranthe lewisii (species) D	Dihydroflavonol 4 reductase (MlDfr)	Erythranthe lewisii (species)	Published - Accepted by Curator
DMRT3	Gait (ability to pace)	Coding, SNP N	Equus caballus horse - (species)	Domesticated	Linkage Mapping	Andersson LS; Larhammar M; Memic F ; et al. (2012) Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. 1 Additional References Petersen JL; Mickelson JR; Rendahl AK (2013) Genome-wide analysis reveals selection for important traits in domestic horse breeds.	GP00000230	DMRT3 F6W2R2	Behavior	Premature stop codon (Ser301Stop) resulting in truncated protein: a single base change at nucleotide position chr23:22999655 causing a premature stop at codon 301 in DMRT3 (DMRT3_Ser301STOP). The allele is expected to encode a truncated protein lacking 1 N	Equus caballus horse - (species)	Equus caballus horse - (species)	DMRT3	Equus caballus horse - (species)	Published - Accepted by Curator
dwarf-8 (d8)	Plant size (dwarfism)	Coding, Deletion N	Zea mays (species) D	Domesticated	Linkage Mapping	Peng J; Richards DE; Hartley NM ; et al. (1999) 'Green revolution' genes encode mutant gibberellin response modulators. 2 Additional References Camus-Kulandaivelu L; Veyrieras JB; Madur D (2006) Maize adaptation to temperate climate: relationship between population structure and polymorphism in[...] Thornsberry JM; Goodman MM; Doebley J (2001) Dwarf8 polymorphisms associate with variation in flowering time.	GP00000241	D8 Q9ST48	Morphology	330bp deletion to V84 N	Zea mays (species)	Zea mays (species) D	dwarf-8 (d8)	Zea mays (species)	Published - Accepted by Curator
EARLY FLOWERING 3 (here = Mat-a)	Flowering time	Coding, Deletion N	Hordeum vulgare (species) D	Domesticated	Linkage Mapping	Zakhrabekova S; Gough SP; Braumann I ; et al. (2012) Induced mutations in circadian clock regulator Mat-a facilitated short-season adaptation and range e[...]	GP00000243	ELF3 O82804	Physiology	4bp deletion resulting in truncated protein ; this deletion seem to have evolved multiple times (fragile site?) N	Hordeum vulgare (species)	Hordeum vulgare (species) D	EARLY FLOWERING 3 (here = Mat-a)	Hordeum vulgare (species)	Published - Accepted by Curator
EARLY FLOWERING 3(ELF3)	Flowering time (latitudinal adaptation)	Coding, Deletion N	Glycine max soybean - (species) D	Domesticated	Linkage Mapping	Lu S; Zhao X; Hu Y ; et al. (2017) Natural variation at the soybean J locus improves adaptation to the tropics and enhances yield.	GP00001683	CYP75B1 Q9SD85	Physiology	recessive allele responsible for the LJ trait - 10-bp deletion predicted to cause a frameshift resulting in premature termination of translation after 195 amino acids in the 714-amino-acid protein N	Glycine max soybean - (species)	Glycine max soybean - (species) D	EARLY FLOWERING 3(ELF3)	Glycine max soybean - (species)	Published - Accepted by Curator
EARLY FLOWERING 3/ EARLY MATURITY 8	Flowering time	Coding, SNP N	Hordeum vulgare (species)	Domesticated	Linkage Mapping	Faure S; Turner AS; Gruszka D ; et al. (2012) Mutation at the circadian clock gene EARLY MATURITY 8 adapts domesticated barley (Hordeum vulgare) t[...]	GP00000245	ELF3 O82804	Physiology	Premature stop codon; C-to-T point mutation in exon 2 N	Hordeum vulgare (species)	Hordeum vulgare (species)	EARLY FLOWERING 3/ EARLY MATURITY 8	Hordeum vulgare (species)	Published - Accepted by Curator
EARLY FLOWERING 3/ EARLYMATURITY8	Flowering time	Coding, Deletion N	Hordeum vulgare (species) D	Domesticated	Linkage Mapping	Faure S; Turner AS; Gruszka D ; et al. (2012) Mutation at the circadian clock gene EARLY MATURITY 8 adapts domesticated barley (Hordeum vulgare) t[...]	GP00000246	ELF3 O82804	Physiology	4bp deletion resulting in truncated protein ; this deletion seem to have evolved multiple times (fragile site?) N	Hordeum vulgare (species)	Hordeum vulgare (species) D	EARLY FLOWERING 3/ EARLYMATURITY8	Hordeum vulgare (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth absence (no enamel production)	Gene Loss, Deletion N	Gallus gallus chicken - (species) D	Intergeneric or Higher	Candidate Gene	Sire JY; Delgado SC; Girondot M (2008) Hen's teeth with enamel cap: from dream to impossibility.	GP00001935	ENAM Q9NRM1	Physiology	synteny of the corresponding region - the gene has been likely deleted from the chicken genome as a consequence of intrachromosomal rearrangements which have probably occurred in the lineage that led to the last common ancestor of modern birds N	Paleosuchus palpebrosus Cuvier's dwarf caiman - (species)	Gallus gallus chicken - (species) D	enamelin (ENAM)	Gallus gallus chicken - (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth absence (no enamel production)	Coding, Deletion N	Eubalaena glacialis North Atlantic right whale - (species) D Megaptera novaeangliae humpback whale - (species) D Eschrichtius robustus grey whale - (species) D Caperea marginata pygmy right whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Murphy WJ ; et al. (2009) Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of[...] 1 Additional References Meredith RW; Gatesy J; Cheng J (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001939	ENAM Q9NRM1	Physiology	1-bp deletion. Various frameshift mutations were found in the distinct species. N	Cetacea whales - (order)	Eubalaena glacialis North Atlantic right whale - (species) D Megaptera novaeangliae humpback whale - (species) D Eschrichtius robustus grey whale - (species) D Caperea marginata pygmy right whale - (species) D	enamelin (ENAM)	Eubalaena glacialis North Atlantic right whale - (species) Megaptera novaeangliae humpback whale - (species) Eschrichtius robustus grey whale - (species) Caperea marginata pygmy right whale - (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth composition (no enamel production)	2 Mutations: Coding Deletion N	Kogia sima dwarf sperm whale - (species) D Kogia breviceps pygmy sperm whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Murphy WJ ; et al. (2009) Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of[...] 1 Additional References Meredith RW; Gatesy J; Cheng J (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001942	ENAM Q9NRM1	Physiology	2 mutations	Physeter catodon sperm whale - (species)	Kogia sima dwarf sperm whale - (species) D Kogia breviceps pygmy sperm whale - (species) D	enamelin (ENAM)	Kogia sima dwarf sperm whale - (species) Kogia breviceps pygmy sperm whale - (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth composition (no enamel production)	3 Mutations: Coding N	Orycteropus afer aardvark - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Murphy WJ ; et al. (2009) Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of[...]	GP00001943	ENAM Q9NRM1	Physiology	3 mutations	Elephantulus rufescens East African long-eared elephant shrew - (species)	Orycteropus afer aardvark - (species) D	enamelin (ENAM)	Orycteropus afer aardvark - (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth composition (no enamel production)	Coding, Unknown N	Manis pentadactyla Chinese pangolin - (species) D Manis tricuspis Tree pangolin - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Murphy WJ ; et al. (2009) Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of[...]	GP00001944	ENAM Q9NRM1	Physiology	multiple deletions and insertions less than 9bp causing frameshift N	Canis lupus familiaris dog - (subspecies)	Manis pentadactyla Chinese pangolin - (species) D Manis tricuspis Tree pangolin - (species) D	enamelin (ENAM)	Manis pentadactyla Chinese pangolin - (species) Manis tricuspis Tree pangolin - (species)	Published - Accepted by Curator
enamelin (ENAM)	Tooth composition (no enamel production)	Coding, Unknown N	Bradypus tridactylus Pale-throated sloth - (species) D Tamandua tetradactyla southern tamandua - (species) D Dasypus novemcinctus nine-banded armadillo - (species) D Euphractus sexcinctus (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Murphy WJ ; et al. (2009) Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of[...]	GP00001945	ENAM Q9NRM1	Physiology	multiple frameshift insertions and deletions N	Canis lupus familiaris dog - (subspecies)	Bradypus tridactylus Pale-throated sloth - (species) D Tamandua tetradactyla southern tamandua - (species) D Dasypus novemcinctus nine-banded armadillo - (species) D Euphractus sexcinctus (species) D	enamelin (ENAM)	Bradypus tridactylus Pale-throated sloth - (species) Tamandua tetradactyla southern tamandua - (species) Dasypus novemcinctus nine-banded armadillo - (species) Euphractus sexcinctus (species)	Published - Accepted by Curator
enamelysin (MMP20)	Tooth absence (no enamel production)	Coding, Insertion N	Balaenoptera physalus Fin whale - (species) D Balaena mysticetus bowhead whale - (species) D Megaptera novaeangliae humpback whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Cheng J ; et al. (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001940	MMP20 O60882	Physiology	insertion of a CHR-2 SINE retroposon in exon 2 of MMP20 which would result in premature truncation of the MMP20 protein owing to stop codons in all possible reading frames of the CHR-2 SINE. The length of the MMP20 SINE ranges from 302 bp (B. musculus) to 318 bp (B. physalus). This mutation is found in eight investigated species of baleen whales. Other inactivating mutations (nonsense and frameshift mutations) are found in various species N	Physeter catodon sperm whale - (species)	Balaenoptera physalus Fin whale - (species) D Balaena mysticetus bowhead whale - (species) D Megaptera novaeangliae humpback whale - (species) D	enamelysin (MMP20)	Balaenoptera physalus Fin whale - (species) Balaena mysticetus bowhead whale - (species) Megaptera novaeangliae humpback whale - (species)	Published - Accepted by Curator
enamelysin (MMP20)	Tooth composition (no enamel production)	Coding, SNP N	Kogia breviceps pygmy sperm whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Cheng J ; et al. (2011) Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales[...]	GP00001941	MMP20 O60882	Physiology	opal stop codon (TGA) in the propeptide-coding region of MMP20 exon 2 in a single individual of the pygmy sperm whale Kogia breviceps N	Kogia sima dwarf sperm whale - (species)	Kogia breviceps pygmy sperm whale - (species) D	enamelysin (MMP20)	Kogia breviceps pygmy sperm whale - (species)	Published - Accepted by Curator
Epithiospecifier protein (ESP)	Plant secondary metabolite (glucosinolate) Herbivore resistance	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Lambrix V; Reichelt M; Mitchell-Olds T ; et al. (2001) The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and i[...]	GP00000279	ESP Q8RY71	Physiology Physiology	deletion of 124 bases that eliminates a splice site and 100 nucleotides of the ORF N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Epithiospecifier protein (ESP)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000286	ERG3 P32353	Physiology	Arg63Stop A187T in line 21 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001744	ERG3 P32353	Physiology	Ser76Stop C227A in line 22 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001745	ERG3 P32353	Physiology	Ser95Stop C284A in line 23 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001746	ERG3 P32353	Physiology	Trp205Stop G615A in line 24 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001747	ERG3 P32353	Physiology	Trp205Stop G615A in line 25 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001748	ERG3 P32353	Physiology	Trp205Stop G615A in line 26 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001749	ERG3 P32353	Physiology	Trp205Stop G615A in line 27 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001750	ERG3 P32353	Physiology	29-bp duplication in line 28 at nucleotide position 641 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001751	ERG3 P32353	Physiology	Trp219Stop G656A in line 29 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001752	ERG3 P32353	Physiology	Gly235Ser G703A in line 30 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001753	ERG3 P32353	Physiology	Tyr299Stop C897A in line 31 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001754	ERG3 P32353	Physiology	Gly300Arg G898C in line 32 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001755	ERG3 P32353	Physiology	Asp307Ala A920C in line 33 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001756	ERG3 P32353	Physiology	1-bp deletion in line 34 A980- N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG3	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00001757	ERG3 P32353	Physiology	60-bp deletion at position 253 in line 35 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
ERG5	Xenobiotic resistance (drug)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Lo DS; Otto SP (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of[...]	GP00000287	ERG5 P54781	Physiology	60bp deletion N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	ERG5	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
FAD2 (BnaA.FAD2.a)	Oil composition Oil yield	Coding, Insertion N	Brassica napus rape - (species) D	Domesticated	Linkage Mapping	Yang Q; Fan C; Guo Z ; et al. (2012) Identification of FAD2 and FAD3 genes in Brassica napus genome and development of allele-specific ma[...]	GP00000302	FAD2 P46313	Physiology Physiology	4bp insertion resulting in frameshift and premature stop codon N	Brassica napus rape - (species)	Brassica napus rape - (species) D	FAD2 (BnaA.FAD2.a)	Brassica napus rape - (species)	Published - Accepted by Curator
FAD2A	Oil composition (oleate levels)	Coding, SNP N	Arachis hypogaea peanut - (species) D	Domesticated	Candidate Gene	Jung S; Powell G; Moore K ; et al. (2000) The high oleate trait in the cultivated peanut [Arachis hypogaea L]. II. Molecular basis and genetic[...]	GP00002075	FAD2A E2GJC1	Physiology	D150N in a residue that is absolutely conserved among other desaturases N	Arachis hypogaea peanut - (species)	Arachis hypogaea peanut - (species) D	FAD2A	Arachis hypogaea peanut - (species)	Published - Accepted by Curator
FAD2B	Oil composition (oleate levels)	Coding, Insertion N	Arachis hypogaea peanut - (species) D	Domesticated	Candidate Gene	Patel M; Jung S; Moore K ; et al. (2004) High-oleate peanut mutants result from a MITE insertion into the FAD2 gene.	GP00002073	FAD2B Q9LKK6	Physiology	insertion of 205-bp miniature inverted-repeat transposable element (MITE) called ahMITE1 at position 665 near the center of the coding region in the case of MF; which causes a frameshift N	Arachis hypogaea peanut - (species)	Arachis hypogaea peanut - (species) D	FAD2B	Arachis hypogaea peanut - (species)	Published - Accepted by Curator
FAD2B	Oil composition (oleate levels)	Coding, Insertion N	Arachis hypogaea peanut - (species) D	Domesticated	Candidate Gene	Patel M; Jung S; Moore K ; et al. (2004) High-oleate peanut mutants result from a MITE insertion into the FAD2 gene.	GP00002074	FAD2B Q9LKK6	Physiology	insertion of 205-bp miniature inverted-repeat transposable element (MITE) called ahMITE1 at position 997 of the coding region; which causes a frameshift N	Arachis hypogaea peanut - (species)	Arachis hypogaea peanut - (species) D	FAD2B	Arachis hypogaea peanut - (species)	Published - Accepted by Curator
FGF5 (fibroblast growth factor 5)	Hair length	Coding, Deletion N	Equus asinus ass - (species) D	Intraspecific	Candidate Gene	Legrand R; Tiret L; Abitbol M (2014) Two recessive mutations in FGF5 are associated with the long-hair phenotype in donkeys.	GP00001369	Fgf5 P15656	Morphology	c.433_434delAT frameshift deletion leading to a stop codon at position 159 N	Equus asinus ass - (species)	Equus asinus ass - (species) D	FGF5 (fibroblast growth factor 5)	Equus asinus ass - (species)	Published - Accepted by Curator
FGF5 (fibroblast growth factor 5)	Hair length	Coding, SNP N	Equus asinus ass - (species) D	Intraspecific	Candidate Gene	Legrand R; Tiret L; Abitbol M (2014) Two recessive mutations in FGF5 are associated with the long-hair phenotype in donkeys.	GP00001370	Fgf5 P15656	Morphology	c.245G>A nonsense mutation leading to stop codon at position 82 N	Equus asinus ass - (species)	Equus asinus ass - (species) D	FGF5 (fibroblast growth factor 5)	Equus asinus ass - (species)	Published - Accepted by Curator
Fgfr1a1	Scales (loss)	Coding, Deletion N	Cyprinus carpio common carp - (species) D	Domesticated	Candidate Gene	Rohner N; Bercsényi M; Orbán L ; et al. (2009) Duplication of fgfr1 permits Fgf signaling to serve as a target for selection during domestication.	GP00000312	fgfr1a Q90Z00	Morphology	deletion of 310 bp N	Cyprinus carpio common carp - (species)	Cyprinus carpio common carp - (species) D	Fgfr1a1	Cyprinus carpio common carp - (species)	Published - Accepted by Curator
Flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers; pubescence; seeds)	Coding, Deletion N	Glycine soja (species) D	Intraspecific	Candidate Gene	Guo Y; Qiu LJ (2013) Allele-specific marker development and selection efficiencies for both flavonoid 3'-hydroxylase and [...]	GP00000315	CYP75B1 Q9SD85	Morphology	-1bp at +973 resulting in premature stop codon N	Glycine max soybean - (species)	Glycine soja (species) D	Flavonoid 3'-hydroxylase (F3'H)	Glycine soja (species)	Published - Accepted by Curator
Flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers; pubescence; seeds)	Coding, Deletion N	Glycine soja (species) D	Intraspecific	Candidate Gene	Guo Y; Qiu LJ (2013) Allele-specific marker development and selection efficiencies for both flavonoid 3'-hydroxylase and [...]	GP00000316	CYP75B1 Q9SD85	Morphology	-1bp at +1164 resulting in premature stop codon N	Glycine max soybean - (species)	Glycine soja (species) D	Flavonoid 3'-hydroxylase (F3'H)	Glycine soja (species)	Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers)	Coding, Insertion N	Ipomoea purpurea common morning-glory - (species) D	Domesticated	Candidate Gene	Zufall RA; Rausher MD (2003 Nov-Dec) The genetic basis of a flower color polymorphism in the common morning glory (Ipomoea purpurea). 3 Additional References Hoshino A; Morita Y; Choi JD (2003) Spontaneous mutations of the flavonoid 3'-hydroxylase gene conferring reddish flowers in the three m[...] Zufall RA; Rausher MD (2004) Genetic changes associated with floral adaptation restrict future evolutionary potential. Des Marais DL; Rausher MD (2010) Parallel evolution at multiple levels in the origin of hummingbird pollinated flowers in Ipomoea.	GP00000319	CYP75B1 Q9SD85	Morphology	insertion of the 0.55-kb DNA transposable element Tip201 belonging to the Ac/Ds superfamily. No excision of Tip201 from the F3'H gene could be detected. Both splicing and polyadenylation patterns of the F3'H transcripts were affected by the Tip201 integration. N	Ipomoea purpurea common morning-glory - (species)	Ipomoea purpurea common morning-glory - (species) D	flavonoid 3'-hydroxylase (F3'H)	Ipomoea purpurea common morning-glory - (species)	Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)	Coloration (seed; pods)	Coding, Deletion N	Glycine max soybean - (species) D	Domesticated	Linkage Mapping	Toda K; Yang D; Yamanaka N ; et al. (2002) A single-base deletion in soybean flavonoid 3'-hydroxylase gene is associated with gray pubescence c[...] 1 Additional References Zabala G; Vodkin L (2003) Cloning of the pleiotropic T locus in soybean and two recessive alleles that differentially affect s[...]	GP00000321	CYP75B1 Q9SD85	Morphology	1bp deletion resulting in frameshift N	Glycine max soybean - (species)	Glycine max soybean - (species) D	flavonoid 3'-hydroxylase (F3'H)	Glycine max soybean - (species)	Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers)	Coding, SNP N	Ipomoea nil Japanese morning glory - (species) D	Domesticated	Candidate Gene	Hoshino A; Morita Y; Choi JD ; et al. (2003) Spontaneous mutations of the flavonoid 3'-hydroxylase gene conferring reddish flowers in the three m[...]	GP00002087	CYP75B1 Q9SD85	Morphology	nonsense mutation caused by a single C to T base transition generating the stop codon TGA. N	Ipomoea nil Japanese morning glory - (species)	Ipomoea nil Japanese morning glory - (species) D	flavonoid 3'-hydroxylase (F3'H)	Ipomoea nil Japanese morning glory - (species)	Published - Accepted by Curator
flavonoid 3'-hydroxylase (F3'H)	Coloration (flowers)	Coding, Insertion N	Ipomoea tricolor (species) D	Domesticated	Candidate Gene	Hoshino A; Morita Y; Choi JD ; et al. (2003) Spontaneous mutations of the flavonoid 3'-hydroxylase gene conferring reddish flowers in the three m[...]	GP00002088	CYP75B1 Q9SD85	Morphology	a single T insertion generating the stop codon TAG. The accumulation of the F3'H transcripts is drastically reduced by the nonsense-mediated RNA decay. N	Ipomoea tricolor (species)	Ipomoea tricolor (species) D	flavonoid 3'-hydroxylase (F3'H)	Ipomoea tricolor (species)	Published - Accepted by Curator
flavonoid 3';5'-hydroxylase (F3'5'H)	Coloration (flowers; pubescence; seeds)	Coding, Insertion N	Glycine soja (species) D	Intraspecific	Candidate Gene	Guo Y; Qiu LJ (2013) Allele-specific marker development and selection efficiencies for both flavonoid 3'-hydroxylase and [...]	GP00000322	CYP75A2 P37120	Morphology	53bp insertion at +1352 N	Glycine max soybean - (species)	Glycine soja (species) D	flavonoid 3';5'-hydroxylase (F3'5'H)	Glycine soja (species)	Published - Accepted by Curator
flavonoid 3';5'-hydroxylase (F3'5'H)	Coloration (flowers)	Gene Loss, Complex Change N	Iochroma cyaneum (species)	Interspecific	Linkage Mapping	Smith SD; Rausher MD (2011) Gene loss and parallel evolution contribute to species difference in flower color.	GP00000324	CYP75A2 P37120	Morphology	Large deletion N	Iochroma cyaneum (species)	Iochroma cyaneum (species)	flavonoid 3';5'-hydroxylase (F3'5'H)	Iochroma cyaneum (species)	Published - Accepted by Curator
flavonoid 3';5'-hydroxylase (F3'5'H)	Coloration (flowers)	Coding, Deletion N	Pisum sativum pea - (species) D	Domesticated	Linkage Mapping	Moreau C; Ambrose MJ; Turner L ; et al. (2012) The B gene of pea encodes a defective flavonoid 3',5'-hydroxylase, and confers pink flower color.	GP00000327	CYP75A2 P37120	Morphology	23bp deletion reuslting in frameshift and truncated protein N	Pisum sativum pea - (species)	Pisum sativum pea - (species) D	flavonoid 3';5'-hydroxylase (F3'5'H)	Pisum sativum pea - (species)	Published - Accepted by Curator
FLC (Flowering Locus C)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Werner JD; Borevitz JO; Uhlenhaut NH ; et al. (2005) FRIGIDA-independent variation in flowering time of natural Arabidopsis thaliana accessions. 1 Additional References Ågren J; Oakley CG; Lundemo S (2017) Adaptive divergence in flowering time among natural populations of Arabidopsis thaliana: Estimates o[...]	GP00000330	FLC Q9S7Q7	Physiology	Substitution creating premature Stop (codon 158) N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	FLC (Flowering Locus C)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
FLC-2	Flowering time	Coding, Deletion N	Brassica oleracea wild cabbage - (species) D	Domesticated	Linkage Mapping	Okazaki K; Sakamoto K; Kikuchi R ; et al. (2007) Mapping and characterization of FLC homologs and QTL analysis of flowering time in Brassica oleracea[...]	GP00000339	FLC Q9S7Q7	Physiology	1bp deletion resulting in frameshift N	Brassica oleracea wild cabbage - (species)	Brassica oleracea wild cabbage - (species) D	FLC-2	Brassica oleracea wild cabbage - (species)	Published - Accepted by Curator
FLM (MAF1)	Flowering time	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Werner JD; Borevitz JO; Warthmann N ; et al. (2005) Quantitative trait locus mapping and DNA array hybridization identify an FLM deletion as a cause for[...]	GP00000341	AGL27 Q9AT76	Physiology	Deletion of entire gene N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	FLM (MAF1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Flowering locus T (FT1)	Flowering time	Coding, Deletion N	Helianthus annuus common sunflower - (species) D	Domesticated	Linkage Mapping	Blackman BK; Strasburg JL; Raduski AR ; et al. (2010) The role of recently derived FT paralogs in sunflower domestication.	GP00000346	FT Q9SXZ2	Physiology	1bp deletion; frameshift N	Helianthus annuus common sunflower - (species)	Helianthus annuus common sunflower - (species) D	Flowering locus T (FT1)	Helianthus annuus common sunflower - (species)	Published - Accepted by Curator
FOXI3	Hairless phenotype	Coding, Insertion N	Canis lupus familiaris dog - (subspecies) D	Domesticated	Association Mapping	Drögemüller C; Karlsson EK; Hytönen MK ; et al. (2008) A mutation in hairless dogs implicates FOXI3 in ectodermal development.	GP00000351	FOXI3 B5RHS5	Morphology	Frameshift; 7-bp duplication within exon 1 N	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	FOXI3	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
FPN2	Metal tolerance	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Morrissey J; Baxter IR; Lee J ; et al. (2009) The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis.	GP00000354	IREG2 F4KGN5	Physiology	1bp insertion resulting in frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	FPN2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Johanson U; West J; Lister C ; et al. (2000) Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering tim[...]	GP00000357	FRI P0DH90	Physiology	16bp deletion aa313-318 in exon 2 and premature stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Indel N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Johanson U; West J; Lister C ; et al. (2000) Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering tim[...] 1 Additional References Shindo C; Aranzana MJ; Lister C (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000358	FRI P0DH90	Physiology	376 bp deletion and 31 bp insertion that delete amino acid 1-15 and at best produce a 45-aa protein N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Indel N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...]	GP00000359	FRI P0DH90	Physiology	Del 2257-2355 in exon 3; deletion of 99 bp combined with an insertion of 61 bp N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...]	GP00000360	FRI P0DH90	Physiology	1bp deletion at 1487 in exon 1 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...]	GP00000361	FRI P0DH90	Physiology	1bp insertion at 766 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...] 1 Additional References Shindo C; Aranzana MJ; Lister C (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000362	FRI P0DH90	Physiology	Insertion 1 bp at 1454 in exon 1 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...]	GP00000363	FRI P0DH90	Physiology	Trp240* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Le Corre V; Roux F; Reboud X (2002) DNA polymorphism at the FRIGIDA gene in Arabidopsis thaliana: extensive nonsynonymous variation is c[...]	GP00000364	FRI P0DH90	Physiology	Glu361* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Gazzani S; Gendall AR; Lister C ; et al. (2003) Analysis of the molecular basis of flowering time variation in Arabidopsis accessions.	GP00000365	FRI P0DH90	Physiology	K232* in exon 1 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000366	FRI P0DH90	Physiology	deletion; E430* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000369	FRI P0DH90	Physiology	deletion resulting in S121* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000370	FRI P0DH90	Physiology	deletion; AF375-6* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000371	FRI P0DH90	Physiology	insertion; I490* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000372	FRI P0DH90	Physiology	insertion; T258* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000373	FRI P0DH90	Physiology	Y162* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida (FRI)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Shindo C; Aranzana MJ; Lister C ; et al. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis.	GP00000374	FRI P0DH90	Physiology	K170* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida (FRI)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Frigida like 1 (FRL1)	Flowering time	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Schläppi MR (2006) FRIGIDA LIKE 2 is a functional allele in Landsberg erecta and compensates for a nonsense allele of F[...]	GP00000376	FRL1 Q9FFF1	Physiology	E279* in the middle of the conceptual protein sequence N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	Frigida like 1 (FRL1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
FUT2	ABO antigen blood type	Coding, Deletion N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Kelly RJ; Rouquier S; Giorgi D ; et al. (1995) Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransfera[...] 1 Additional References Pang H; Fujitani N; Soejima M (2000) Two distinct Alu-mediated deletions of the human ABO-secretor (FUT2) locus in Samoan and Bangladeshi[...]	GP00000379	FUT2 Q10981	Physiology	9.3 kb deletion mediated by recombination between Alu sequences N	Homo sapiens human - (species)	Homo sapiens human - (species) D	FUT2	Homo sapiens human - (species)	Published - Accepted by Curator
FUT2	ABO antigen blood type	Coding, Deletion N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Kelly RJ; Rouquier S; Giorgi D ; et al. (1995) Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransfera[...] 2 Additional References Pang H; Fujitani N; Soejima M (2000) Two distinct Alu-mediated deletions of the human ABO-secretor (FUT2) locus in Samoan and Bangladeshi[...] Koda Y; Soejima M; Johnson PH (2000) An Alu-mediated large deletion of the FUT2 gene in individuals with the ABO-Bombay phenotype.	GP00000380	FUT2 Q10981	Physiology	10 kb deletion mediated by recombination between Alu sequences N	Homo sapiens human - (species)	Homo sapiens human - (species) D	FUT2	Homo sapiens human - (species)	Published - Accepted by Curator
FUT2	ABO antigen blood type	Coding, SNP N	Homo sapiens human - (species)	Intraspecific	Candidate Gene	Kelly RJ; Rouquier S; Giorgi D ; et al. (1995) Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransfera[...] 1 Additional References Ferrer-Admetlla A; Sikora M; Laayouni H (2009) A natural history of FUT2 polymorphism in humans.	GP00000381	FUT2 Q10981	Physiology	premature stop at codon 143: TGG>TGA N	Homo sapiens human - (species)	Homo sapiens human - (species)	FUT2	Homo sapiens human - (species)	Published - Accepted by Curator
gastrin	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001914	GAST P01350	Physiology	Absence of the gene in the genome sequence - high synteny N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	gastrin	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
GLABROUS1	Trichome density (leaf)	Gene Loss, Deletion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...] 1 Additional References Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...]	GP00001238	GL1 P27900	Morphology	gene loss: -4.7KB at position -948bp N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	GLABROUS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
GLABROUS1	Trichome density (leaf)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...] 1 Additional References Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...]	GP00001240	GL1 P27900	Morphology	+1bp at position 352 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	GLABROUS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
GLABROUS1	Trichome density (leaf)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...] 1 Additional References Hauser MT; Harr B; Schlötterer C (2001) Trichome distribution in Arabidopsis thaliana and its close relative Arabidopsis lyrata: molecular a[...]	GP00001241	GL1 P27900	Morphology	-1bp at position 203 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	GLABROUS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
glb-5	CO2 avoidance Aggregation behavior	Coding, Indel N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	McGrath PT; Rockman MV; Zimmer M ; et al. (2009) Quantitative mapping of a digenic behavioral trait implicates globin variation in C. elegans sensory[...] 2 Additional References Bendesky A; Pitts J; Rockman MV (2012) Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus [...] Persson A; Gross E; Laurent P (2009) Natural variation in a neural globin tunes oxygen sensing in wild Caenorhabditis elegans.	GP00000399	glb-5 A3RMS5	Behavior Behavior	765bp insertion/duplication resulting in a truncation of the last 179 amino acids of the protein and the inclusion of 40 different residues N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	glb-5	Caenorhabditis elegans (species)	Published - Accepted by Curator
GLC-1	Xenobiotic resistance (antihelmintics)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Ghosh R; Andersen EC; Shapiro JA ; et al. (2012) Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans.	GP00000400	glc-1 G5EBR3	Physiology	4aa deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	GLC-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
GLO(T)	Flower morphology (anther elevation)	Coding, Insertion N	Primula vulgaris (species) D	Intraspecific	Linkage Mapping	Li J; Cocker JM; Wright J ; et al. (2016) Genetic architecture and evolution of the S locus supergene in Primula vulgaris.	GP00001393	GLO Q03378	Morphology	A 2.5 kb retrotransposon in exon 2 severely truncates the protein N	Primula vulgaris (species)	Primula vulgaris (species) D	GLO(T)	Primula vulgaris (species)	Published - Accepted by Curator
GPRC6A	Cell signaling (membrane receptor activity)	Coding, Deletion N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Jørgensen S; Have CT; Underwood CR ; et al. (2017) Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Contr[...]	GP00001671	GPRC6A Q5T6X5	Physiology	KGRKLP>KGK--Y in the third intracellular loop (ICL3) responsible for the intracellular retention and lack of function N	Homo sapiens human - (species)	Homo sapiens human - (species) D	GPRC6A	Homo sapiens human - (species)	Published - Accepted by Curator
GPRC6A	Cell signaling (membrane receptor activity)	Coding, SNP N	Homo sapiens human - (species) D	Intraspecific	Candidate Gene	Jørgensen S; Have CT; Underwood CR ; et al. (2017) Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Contr[...]	GP00001672	GPRC6A Q5T6X5	Physiology	C>T (aa57) located in the first exon resulting in a premature Stop-codon and non-functional protein N	Homo sapiens human - (species)	Homo sapiens human - (species) D	GPRC6A	Homo sapiens human - (species)	Published - Accepted by Curator
Growth Hormone Receptor	Body size (height)	Coding, SNP N	Homo sapiens human - (species)	Intraspecific	Association Mapping	Zoledziewska M; Sidore C; Chiang CWK ; et al. (2015) Height-reducing variants and selection for short stature in Sardinia.	GP00000415	GHR P10912	Morphology	Arg61* N	Homo sapiens human - (species)	Homo sapiens human - (species)	Growth Hormone Receptor	Homo sapiens human - (species)	Published - Accepted by Curator
GS3	Grain size	Coding, SNP N	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Fan C; Xing Y; Mao H ; et al. (2006) GS3, a major QTL for grain length and weight and minor QTL for grain width and thickness in rice, en[...] 1 Additional References Huang X; Wei X; Sang T (2010) Genome-wide association studies of 14 agronomic traits in rice landraces.	GP00000417	GS3 C6L686	Morphology	C55*;TGC>TGA causing a 178-aa truncation in the C-terminus of the predicted protein N	Oryza sativa rice - (species)	Oryza sativa rice - (species)	GS3	Oryza sativa rice - (species)	Published - Accepted by Curator
Gulo	Vitamin-C synthesis (loss)	Coding, Complex Change N	Cavia porcellus domestic guinea pig - (species)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000420	Gulo P58710	Physiology	pseudogenization involving invalidating mutations at most exons N	Mammalia mammals - (class)	Cavia porcellus domestic guinea pig - (species)	Gulo	Cavia porcellus domestic guinea pig - (species)	Published - Accepted by Curator
Gulo	Vitamin-C synthesis (loss)	Coding, Complex Change N	Myotis lucifugus little brown bat - (species)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000421	Gulo P58710	Physiology	pseudogenization N	Mammalia mammals - (class)	Myotis lucifugus little brown bat - (species)	Gulo	Myotis lucifugus little brown bat - (species)	Published - Accepted by Curator
Gulo	Vitamin-C synthesis (loss)	Coding, Complex Change N	Primates (order)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000422	Gulo P58710	Physiology	pseudogenization N	Mammalia mammals - (class)	Primates (order)	Gulo	Primates (order)	Published - Accepted by Curator
Gulo	Vitamin-C synthesis (loss)	Coding, Complex Change N	Pteropus vampyrus large flying fox - (species)	Intergeneric or Higher	Association Mapping	Hiller M; Schaar BT; Indjeian VB ; et al. (2012) A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among [...]	GP00000423	Gulo P58710	Physiology	pseudogenization N	Mammalia mammals - (class)	Pteropus vampyrus large flying fox - (species)	Gulo	Pteropus vampyrus large flying fox - (species)	Published - Accepted by Curator
GW2	Grain size	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Song XJ; Huang W; Shi M ; et al. (2007) A QTL for rice grain width and weight encodes a previously unknown RING-type E3 ubiquitin ligase.	GP00000424	GW2 A4GWX9	Morphology	1bp deletion resulting in a premature stop codon in exon 4; the premature stop codon led to truncation of 310 amino acid residues N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	GW2	Oryza sativa rice - (species)	Published - Accepted by Curator
GW2	Grain size	Coding, Insertion N	Triticum aestivum bread wheat - (species) D	Domesticated	Linkage Mapping	Yang Z; Bai Z; Li X ; et al. (2012) SNP identification and allelic-specific PCR markers development for TaGW2, a gene linked to wheat ke[...]	GP00000425	GW2 A4GWX9	Morphology	1bp insertion resulting in premature stop codon N	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species) D	GW2	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, SNP N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Linkage Mapping	Zhao J; Jin L; Yang Y ; et al. (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] 1 Additional References Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000426	ABCA2 A0A0S0G7V0	Physiology	Pro53* (161T>A) N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Deletion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Xu X; Yu L; Wu Y (2005) Disruption of a cadherin gene associated with resistance to Cry1Ac {delta}-endotoxin of Bacillus thu[...] 2 Additional References Zhao J; Jin L; Yang Y (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000427	ABCA2 A0A0S0G7V0	Physiology	10kb deletion N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Yang Y; Chen H; Wu S ; et al. (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...] 1 Additional References Zhao J; Jin L; Yang Y (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...]	GP00000428	ABCA2 A0A0S0G7V0	Physiology	Insertion of a LTR retrotransposon N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Yang Y; Chen H; Wu S ; et al. (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...] 1 Additional References Zhao J; Jin L; Yang Y (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...]	GP00000429	ABCA2 A0A0S0G7V0	Physiology	Insertion of a LTR retrotransposon N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Zhao J; Jin L; Yang Y ; et al. (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] 1 Additional References Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000430	ABCA2 A0A0S0G7V0	Physiology	Insertion of an incomplete RNA transposon (1498bp) N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Zhao J; Jin L; Yang Y ; et al. (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] 1 Additional References Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000431	ABCA2 A0A0S0G7V0	Physiology	Insertion of a DNA transposon N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Zhao J; Jin L; Yang Y ; et al. (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] 1 Additional References Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000432	ABCA2 A0A0S0G7V0	Physiology	Insertion of a LTR retrotransposon N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
Ha_BtR	Xenobiotic resistance (insecticide; Bt Cry1Ac toxin)	Coding, Insertion N	Helicoverpa armigera cotton bollworm - (species) D	Intraspecific	Candidate Gene	Zhao J; Jin L; Yang Y ; et al. (2010) Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicover[...] 1 Additional References Yang Y; Chen H; Wu S (2006) Identification and molecular detection of a deletion mutation responsible for a truncated cadherin o[...]	GP00000433	ABCA2 A0A0S0G7V0	Physiology	Insertion of a LTR retrotransposon N	Helicoverpa armigera cotton bollworm - (species)	Helicoverpa armigera cotton bollworm - (species) D	Ha_BtR	Helicoverpa armigera cotton bollworm - (species)	Published - Accepted by Curator
HAC1 (=ATQ1)	Xenobiotic resistance (soil contamination; arsenate)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Chao DY; Chen Y; Chen J ; et al. (2014) Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting ars[...]	GP00000435	HAC1 Q9C5X9	Physiology	1bp deletion resulting in frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	HAC1 (=ATQ1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, Insertion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Doi K; Izawa T; Fuse T ; et al. (2004) Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-[...]	GP00000439	HD1 Q9FDX8	Physiology	Retro-element-like inserted in exon 2 N	Oryza glaberrima African rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Yano M; Katayose Y; Ashikari M ; et al. (2000) Hd1, a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the Ara[...] 1 Additional References Takahashi Y; Teshima KM; Yokoi S (2009) Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of fl[...]	GP00000441	HD1 Q9FDX8	Physiology	2bp deletion in the putative exon 2 N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Takahashi Y; Teshima KM; Yokoi S ; et al. (2009) Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of fl[...]	GP00001722	HD1 Q9FDX8	Physiology	1bp deletion at position 606 ; presumptive protein truncated N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Takahashi Y; Teshima KM; Yokoi S ; et al. (2009) Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of fl[...]	GP00001723	HD1 Q9FDX8	Physiology	1bp deletion at position 321 ; presumptive protein truncated N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Takahashi Y; Teshima KM; Yokoi S ; et al. (2009) Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of fl[...]	GP00001724	HD1 Q9FDX8	Physiology	4bp deletion at position 1089 ; presumptive protein truncated N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd1	Flowering time	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Candidate Gene	Takahashi Y; Teshima KM; Yokoi S ; et al. (2009) Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of fl[...]	GP00001725	HD1 Q9FDX8	Physiology	C to T – stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Hd1	Oryza sativa rice - (species)	Published - Accepted by Curator
Hd6a	Flowering time	Coding, SNP N	Oryza sativa rice - (species)	Domesticated	Linkage Mapping	Takahashi Y; Shomura A; Sasaki T ; et al. (2001) Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the alpha subunit [...]	GP00000442	HD6 Q9AR27	Physiology	K91*; AAG>TAG N	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Hd6a	Oryza sativa rice - (species)	Published - Accepted by Curator
HEADING DATE 1	Flowering time (latitudinal adaptation)	Cis-regulatory, Insertion N	Oryza sativa Japonica Group Japanese rice - (no rank) D	Domesticated	Candidate Gene	Goretti D; Martignago D; Landini M ; et al. (2017) Transcriptional and Post-transcriptional Mechanisms Limit Heading Date 1 (Hd1) Function to Adapt Ric[...]	GP00001674	HD1 Q9FDX8	Physiology	Hd1(EH) allele with a 4.4 kb mobile element inserted at position -166pb that suppressed gene transcription N	Oryza sativa rice - (species)	Oryza sativa Japonica Group Japanese rice - (no rank) D	HEADING DATE 1	Oryza sativa Japonica Group Japanese rice - (no rank)	Published - Accepted by Curator
Heading Date 1 (HD1)	Flowering time	Coding, Deletion N	Sorghum virgatum (species) D	Domesticated	Association Mapping	Liu H; Liu H; Zhou L ; et al. (2015) Parallel Domestication of the Heading Date 1 Gene in Cereals.	GP00001408	CO Q39057	Physiology	5bp deletion in the coding sequence leading to gene frameshift N	Sorghum bicolor sorghum - (species)	Sorghum virgatum (species) D	Heading Date 1 (HD1)	Sorghum virgatum (species)	Published - Accepted by Curator
Heading Date 1 (HD1)	Flowering time	Coding, Deletion N	Sorghum (genus) D	Interspecific	Association Mapping	Liu H; Liu H; Zhou L ; et al. (2015) Parallel Domestication of the Heading Date 1 Gene in Cereals.	GP00001409	CO Q39057	Physiology	80bp deletion in first exon leading to gene frameshift N	Sorghum (genus)	Sorghum (genus) D	Heading Date 1 (HD1)	Sorghum (genus)	Published - Accepted by Curator
Heading Date 1 (HD1)	Flowering time	Coding, SNP N	Setaria italica foxtail millet - (species) D	Domesticated	Association Mapping	Liu H; Liu H; Zhou L ; et al. (2015) Parallel Domestication of the Heading Date 1 Gene in Cereals.	GP00001410	CO Q39057	Physiology	splicing variant at position 787 GT>AT resulting in a splicing shift to position 754 introducing a deletion of 33 bp in the transcript and 11 aa in the protein N	Setaria italica foxtail millet - (species)	Setaria italica foxtail millet - (species) D	Heading Date 1 (HD1)	Setaria italica foxtail millet - (species)	Published - Accepted by Curator
heavy metal atpase3 (HMA3)	Metal tolerance	Coding, Deletion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Chao DY; Silva A; Baxter I ; et al. (2012) Genome-wide association studies identify heavy metal ATPase3 as the primary determinant of natural v[...]	GP00000444	HMA3 P0CW78	Physiology	1-bp deletion resulting in a premature stop codon resulting in hypofunctional transporter. This is a high-frequency allele; suggesting the hyper-functional alleles are only selected in Cd-rich soils N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	heavy metal atpase3 (HMA3)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
High mobility AT-hook 2 (HMGA2)	Body size (dwarfism) Cranio-facial morphology	Gene Loss, Deletion N	Oryctolagus cuniculus rabbit - (species) D	Domesticated	Association Mapping	Carneiro M; Hu D; Archer J ; et al. (2017) Dwarfism and Altered Craniofacial Development in Rabbits Is Caused by a 12.1 kb Deletion at the HMGA[...]	GP00001675	HMGA2 P52926	Morphology Morphology	deletion of 12.1 kb overlapping the promoter region and first three exons leading to inactivation of the gene. The 5'-end of this deletion overlaps a CSINE2 element N	Oryctolagus cuniculus rabbit - (species)	Oryctolagus cuniculus rabbit - (species) D	High mobility AT-hook 2 (HMGA2)	Oryctolagus cuniculus rabbit - (species)	Published - Accepted by Curator
HM1 = HC toxin reductase (HCTR) [possible pseudo-replicate from other Maize entry]	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Linkage Mapping	Johal GS; Briggs SP (1992) Reductase activity encoded by the HM1 disease resistance gene in maize. 1 Additional References Multani DS; Meeley RB; Paterson AH (1998) Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.	GP00000481	hm1 O49163	Physiology	256-bp transposable element insertion in exon 4 N	Zea mays (species)	Zea mays (species) D	HM1 = HC toxin reductase (HCTR) [possible pseudo-replicate from other Maize entry]	Zea mays (species)	Published - Accepted by Curator
HM2 = HC toxin reductase (HCTR)	Pathogen resistance	Coding, Deletion N	Zea mays (species) D	Domesticated	Candidate Gene	Chintamanani S; Multani DS; Ruess H ; et al. (2008) Distinct mechanisms govern the dosage-dependent and developmentally regulated resistance conferred b[...]	GP00000482	hm2 B8QWA3	Physiology	deletion from exon 2 (nucleotide 420) to beyond the confines of the hm2 gene into an unknown genomic region. N	Zea mays (species)	Zea mays (species) D	HM2 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
HM2 = HC toxin reductase (HCTR)	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Candidate Gene	Chintamanani S; Multani DS; Ruess H ; et al. (2008) Distinct mechanisms govern the dosage-dependent and developmentally regulated resistance conferred b[...]	GP00000483	hm2 B8QWA3	Physiology	8-bp insertion in exon 1 that disrupt the reading frame and introduces a stop codon shortly after the beginning of the gene N	Zea mays (species)	Zea mays (species) D	HM2 = HC toxin reductase (HCTR)	Zea mays (species)	Published - Accepted by Curator
Hox gene cluster	Body plan (number of segments)	Gene Loss, Deletion N	Hypsibius dujardini (species) D Paramacrobiotus richtersi (species) D Milnesium tardigradum (species) D	Intergeneric or Higher	Candidate Gene	Smith FW; Boothby TC; Giovannini I ; et al. (2016) The Compact Body Plan of Tardigrades Evolved by the Loss of a Large Body Region.	GP00001946	Antp P02833	Morphology	The three genes Antp Ubx AbdA are missing in the genome sequences of the three tardigrades. This loss is ancient so difficult to evaluate whether the three genes were lost due to a single mutational event or due to successive mutations. The Hox cluster is disorganized in the H. dujardini genome. N	Drosophila melanogaster fruit fly - (species)	Hypsibius dujardini (species) D Paramacrobiotus richtersi (species) D Milnesium tardigradum (species) D	Hox gene cluster	Hypsibius dujardini (species) Paramacrobiotus richtersi (species) Milnesium tardigradum (species)	Published - Accepted by Curator
HP1D2	Sex determination (sex ratio distortion)	Coding, Deletion N	Drosophila simulans (species) D	Intraspecific	Linkage Mapping	Helleu Q; Gérard PR; Dubruille R ; et al. (2016) Rapid evolution of a Y-chromosome heterochromatin protein underlies sex chromosome meiotic drive.	GP00001467	HP1D2 B4R6K0	Physiology	deletion of 371bp that removes one-half (371bp) of the HP1D2 coding sequence resulting in a frameshift that prevents the translation of the C-terminal chromo shadow domain (CSD) mediating protein N	Drosophila simulans (species)	Drosophila simulans (species) D	HP1D2	Drosophila simulans (species)	Published - Accepted by Curator
Hs1 = pro-1	Pathogen resistance (parasite, nematodes) (nematodes)	Gene Loss, Complex Change N	Beta vulgaris (species)	Domesticated	Linkage Mapping	Cai D; Kleine M; Kifle S ; et al. (1997) Positional cloning of a gene for nematode resistance in sugar beet.	GP00000490	HSPRO1 Q9LY61	Physiology	cDNA sequence lacking in genomic DNA N	Patellifolia (genus)	Beta vulgaris (species)	Hs1 = pro-1	Beta vulgaris (species)	Published - Accepted by Curator
HUA2	Flowering time Shoot morphology	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Wang Q; Sajja U; Rosloski S ; et al. (2007) HUA2 caused natural variation in shoot morphology of A. thaliana.	GP00000491	HUA2 Q9XER9	Physiology Morphology	K525E N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	HUA2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
HUA2	Flowering time Coloration (temperature-dependent)	Coding, Unknown N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Ilk N; Ding J; Ihnatowicz A ; et al. (2015) Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attrib[...] 1 Additional References Doyle MR; Bizzell CM; Keller MR (2005) HUA2 is required for the expression of floral repressors in Arabidopsis thaliana.	GP00001230	HUA2 Q9XER9	Physiology Morphology	Premature stop codon resulting in truncation of 290 C-terminal amino-acids (hua-2-5 Ler allele) N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	HUA2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
HvbHLH1	Coloration	Coding, Deletion N	Hordeum vulgare (species) D	Domesticated	Association Mapping	Cockram J; White J; Zuluaga DL ; et al. (2010) Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genom[...]	GP00000493	bHLH1 E5FCX3	Morphology	16bp deletion resulting in premature stop codon N	Hordeum vulgare (species)	Hordeum vulgare (species) D	HvbHLH1	Hordeum vulgare (species)	Published - Accepted by Curator
KCS18	Oil composition	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Jasinski S; Lécureuil A; Miquel M ; et al. (2012) Natural variation in seed very long chain fatty acid content is controlled by a new isoform of KCS18[...]	GP00000512	FAE1 Q38860	Physiology	L407V N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	KCS18	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Kit (type III receptor protein-tyrosine kinase)	Coloration (coat)	Coding, SNP N	Equus caballus horse - (species) D	Domesticated	Linkage Mapping	Haase B; Brooks SA; Schlumbaum A ; et al. (2007) Allelic heterogeneity at the equine KIT locus in dominant white (W) horses.	GP00000516	Kit P05532	Morphology	Y717* N	Equus caballus horse - (species)	Equus caballus horse - (species) D	Kit (type III receptor protein-tyrosine kinase)	Equus caballus horse - (species)	Published - Accepted by Curator
Kit ligand	Coloration (coat)	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Seitz JJ; Schmutz SM; Thue TD ; et al. (1999) A missense mutation in the bovine MGF gene is associated with the roan phenotype in Belgian Blue and[...]	GP00000101	KITLG P21583	Morphology	Ala193Asp ; missense mutation at position 654 - according to OMIA: c.572C>A p.A191N N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Kit ligand	Bos taurus cattle - (species)	Published - Accepted by Curator
KRT71	Hair type (curly and hairless)	Coding, Deletion N	Rattus norvegicus Norway rat - (species) D	Domesticated	Linkage Mapping	Kuramoto T; Hirano R; Kuwamura M ; et al. (2010) Identification of the rat Rex mutation as a 7-bp deletion at splicing acceptor site of the Krt71 gen[...]	GP00001729	Krt71 Q9R0H5	Morphology	a 7-bp deletion at the splicing acceptor site of intron 1. The deletion provoked a 6-amino acid in-frame deletion (p.Val149_Gln154del) in the alpha-helical rod domain of KRT71 protein N	Rattus norvegicus Norway rat - (species)	Rattus norvegicus Norway rat - (species) D	KRT71	Rattus norvegicus Norway rat - (species)	Published - Accepted by Curator
KRT75	Feathers	Coding, Deletion N	Gallus gallus chicken - (species) D	Domesticated	Linkage Mapping	Ng CS; Wu P; Foley J ; et al. (2012) The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis.	GP00000527	Krt75 Q8BGZ7	Morphology	84bp deletion partially overlapping with exon 5 N	Gallus gallus chicken - (species)	Gallus gallus chicken - (species) D	KRT75	Gallus gallus chicken - (species)	Published - Accepted by Curator
L6	Pathogen resistance	Coding, Insertion N	Linum usitatissimum flax - (species)	Intraspecific	Linkage Mapping	Lawrence GJ; Finnegan EJ; Ayliffe MA ; et al. (1995) The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 an[...]	GP00000528	L6 Q40253	Physiology	Truncated protein due to insertion of a transposable element. Reversion to resistance among descendants of mutant X75 was associated with excision of the newly transposable element Ac. N	Linum usitatissimum flax - (species)	Linum usitatissimum flax - (species)	L6	Linum usitatissimum flax - (species)	Published - Accepted by Curator
lanosterol c14 demethylase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Caenorhabditis elegans (species) D	Intergeneric or Higher	Candidate Gene	Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001951	CYP51A1 Q16850	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Caenorhabditis elegans (species) D	lanosterol c14 demethylase	Caenorhabditis elegans (species)	Published - Accepted by Curator
lanosterol c14 demethylase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intergeneric or Higher	Candidate Gene	Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001952	CYP51A1 Q16850	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Drosophila melanogaster fruit fly - (species) D	lanosterol c14 demethylase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
lanosterol synthase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intergeneric or Higher	Candidate Gene	Kurzchalia TV; Ward S (2003) Why do worms need cholesterol? 1 Additional References Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001949	LSS P48449	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Drosophila melanogaster fruit fly - (species) D	lanosterol synthase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
lanosterol synthase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Caenorhabditis elegans (species) D	Intergeneric or Higher	Candidate Gene	Kurzchalia TV; Ward S (2003) Why do worms need cholesterol? 1 Additional References Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001950	LSS P48449	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Caenorhabditis elegans (species) D	lanosterol synthase	Caenorhabditis elegans (species)	Published - Accepted by Curator
Ldia2 - Diaphanous-related formin	Shell chirality (coiling)	Coding, Deletion N	Lymnaea stagnalis great pond snail - (species) D	Intraspecific	Association Mapping	Davison A; McDowell GS; Holden JM ; et al. (2016) Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog.	GP00000538	DIAPH1 O60610	Morphology	1bp deletion resulting in frame-shift (pseudogenization) N	Lymnaea stagnalis great pond snail - (species)	Lymnaea stagnalis great pond snail - (species) D	Ldia2 - Diaphanous-related formin	Lymnaea stagnalis great pond snail - (species)	Published - Accepted by Curator
LEU2	Xenobiotic resistance	Gene Loss, Complex Change N	Saccharomyces cerevisiae baker's yeast - (species)	Domesticated	Linkage Mapping	Perlstein EO; Ruderfer DM; Roberts DC ; et al. (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast.	GP00000542	LEU2 P04173	Physiology	Deletion N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species)	LEU2	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
LIMONENE-MYRCENE SYNTHASE (LMS)	Fragrance (floral terpenoid volatiles; D -limonene and beta-myrcene)	Coding, SNP N	Erythranthe cardinalis (species) D	Interspecific	Linkage Mapping	Byers KJ; Vela JP; Peng F ; et al. (2014) Floral volatile alleles can contribute to pollinator-mediated reproductive isolation in monkeyflower[...]	GP00001761	LMS W6A2K5	Physiology	G66T transversion mutation in exon 3 of McLMS (KM659024) that results in a nonsense mutation in the McLMS protein (G201X) N	Erythranthe lewisii (species)	Erythranthe cardinalis (species) D	LIMONENE-MYRCENE SYNTHASE (LMS)	Erythranthe cardinalis (species)	Published - Accepted by Curator
Linamarase	Toxicity levels (cyanogenic glucoside)	Gene Loss, Deletion N	Trifolium repens white clover - (species) D	Intraspecific	Linkage Mapping	Olsen KM; Hsu SC; Small LL (2008) Evidence on the molecular basis of the Ac/ac adaptive cyanogenesis polymorphism in white clover (Tri[...] 1 Additional References Olsen KM; Kooyers NJ; Small LL (2013) Recurrent gene deletions and the evolution of adaptive cyanogenesis polymorphisms in white clover (T[...]	GP00000549	LI P26205	Physiology	Gene deletion N	Trifolium repens white clover - (species)	Trifolium repens white clover - (species) D	Linamarase	Trifolium repens white clover - (species)	Published - Accepted by Curator
Lipase Member H	Hair length	Coding, Deletion N	Oryctolagus cuniculus rabbit - (species) D	Domesticated	Linkage Mapping	Diribarne M; Mata X; Chantry-Darmon C ; et al. (2011) A deletion in exon 9 of the LIPH gene is responsible for the rex hair coat phenotype in rabbits (Ory[...]	GP00000550	Liph Q8CIV3	Morphology	1bp deletion resulting in frameshift N	Oryctolagus cuniculus rabbit - (species)	Oryctolagus cuniculus rabbit - (species) D	Lipase Member H	Oryctolagus cuniculus rabbit - (species)	Published - Accepted by Curator
Lysine histidine transporter 1	Pathogen resistance	Coding, Insertion N	Zea mays (species) D	Domesticated	Linkage Mapping	Zhao Y; Lu X; Liu C ; et al. (2012) Identification and fine mapping of rhm1 locus for resistance to Southern corn leaf blight in maize.	GP00000555	LHT1 Q9FKS8	Physiology	354bp insertioin resulting in premature stop codon N	Zea mays (species)	Zea mays (species) D	Lysine histidine transporter 1	Zea mays (species)	Published - Accepted by Curator
mab-23	Male genitalia	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Lints R; Emmons SW (2002) Regulation of sex-specific differentiation and mating behavior in C. elegans by a new member of the [...] 1 Additional References Hodgkin J; Doniach T (1997) Natural variation and copulatory plug formation in Caenorhabditis elegans.	GP00001323	mab-23 G5ECK3	Morphology	TGC>TTC - cysteine of the DM motif transformed into phenylalanine; so is likely to disrupt DNA-binding function N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	mab-23	Caenorhabditis elegans (species)	Published - Accepted by Curator
MC1R	Coloration (albinism)	Coding, Deletion N	Astyanax mexicanus Mexican tetra - (species) D	Intraspecific	Linkage Mapping	Gross JB; Borowsky R; Tabin CJ (2009) A novel role for Mc1r in the parallel evolution of depigmentation in independent populations of the [...]	GP00000567	MC1R Q01726	Morphology	2bp deletion resulting in frameshift N	Astyanax mexicanus Mexican tetra - (species)	Astyanax mexicanus Mexican tetra - (species) D	MC1R	Astyanax mexicanus Mexican tetra - (species)	Published - Accepted by Curator
MC1R	Coloration (coat)	Coding, Deletion N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Klungland H; Våge DI; Gomez-Raya L ; et al. (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. 1 Additional References Joerg H; Fries HR; Meijerink E (1996) Red coat color in Holstein cattle is associated with a deletion in the MSHR gene.	GP00000571	MC1R Q01726	Morphology	1 bp deletion at 104: frameshift and premature stop at amino acid 156 N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	MC1R	Bos taurus cattle - (species)	Published - Accepted by Curator
MC1R	Coloration (coat)	Gene Loss, Complex Change N	Cavia porcellus domestic guinea pig - (species) D	Domesticated	Candidate Gene	Cone RD; Lu D; Koppula S ; et al. (1996) The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation.	GP00000575	MC1R Q01726	Morphology	Deletion of part or all of gene N	Cavia porcellus domestic guinea pig - (species)	Cavia porcellus domestic guinea pig - (species) D	MC1R	Cavia porcellus domestic guinea pig - (species)	Published - Accepted by Curator
MC1R	Coloration (coat)	Coding, Deletion N	Mus musculus house mouse - (species) D	Domesticated	Candidate Gene	Robbins LS; Nadeau JH; Johnson KR ; et al. (1993) Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MS[...]	GP00000582	MC1R Q01726	Morphology	1bp deletion at 183; frameshift & premature stop N	Mus musculus house mouse - (species)	Mus musculus house mouse - (species) D	MC1R	Mus musculus house mouse - (species)	Published - Accepted by Curator
MC1R	Coloration (skin)	Coding, Insertion N	Sus scrofa domesticus domestic pig - (subspecies) D	Domesticated	Linkage Mapping	Kijas JM; Moller M; Plastow G ; et al. (2001) A frameshift mutation in MC1R and a high frequency of somatic reversions cause black spotting in pig[...] 1 Additional References Liu R; Jin L; Long K (2016) Detection of genetic diversity and selection at the coding region of the melanocortin receptor 1 (MC[...]	GP00000631	MC1R Q01726	Morphology	2bp insertion at 23 generates early stop @ 56 & D"121"N ? N	Sus scrofa pig - (species)	Sus scrofa domesticus domestic pig - (subspecies) D	MC1R	Sus scrofa domesticus domestic pig - (subspecies)	Published - Accepted by Curator
MC1R	Coloration (coat)	Coding, SNP N	Bos grunniens domestic yak - (species) D	Domesticated	Candidate Gene	Zhang MQ; Xu X; Luo SJ (2014) The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens).	GP00001354	Mc1r Q01727	Morphology	p.Gln34* and p.Met73Leu and p.Arg142Pro - p.Met73Leu and p.Arg142Pro were only found in heterozygous and their association with phenotype is supposed but not sure N	Bos grunniens domestic yak - (species)	Bos grunniens domestic yak - (species) D	MC1R	Bos grunniens domestic yak - (species)	Published - Accepted by Curator
Melanophilin (MLPH)	Coloration (coat)	Coding, Deletion N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Li W; Sartelet A; Tamma N ; et al. (2016) Reverse genetic screen for loss-of-function mutations uncovers a frameshifting deletion in the melan[...]	GP00000642	Mlph Q91V27	Morphology	10bp deletion in exon1 N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Melanophilin (MLPH)	Bos taurus cattle - (species)	Published - Accepted by Curator
Melanophilin (MLPH)	Coloration (coat)	Coding, Deletion N	Felis catus domestic cat - (species) D	Domesticated	Linkage Mapping	Ishida Y; David VA; Eizirik E ; et al. (2006) A homozygous single-base deletion in MLPH causes the dilute coat color phenotype in the domestic cat[...]	GP00000644	Mlph Q91V27	Morphology	1bp deletion resulting in frameshift N	Felis catus domestic cat - (species)	Felis catus domestic cat - (species) D	Melanophilin (MLPH)	Felis catus domestic cat - (species)	Published - Accepted by Curator
Melanophilin (MLPH)	Coloration (coat)	Coding, Deletion N	Neovison vison American mink - (species) D	Domesticated	Candidate Gene	Cirera S; Markakis MN; Christensen K ; et al. (2013) New insights into the melanophilin (MLPH) gene controlling coat color phenotypes in American mink.	GP00000646	Mlph Q91V27	Morphology	deletion including intron 7 and exon 8 N	Neovison vison American mink - (species)	Neovison vison American mink - (species) D	Melanophilin (MLPH)	Neovison vison American mink - (species)	Published - Accepted by Curator
Melanophilin (MLPH)	Coloration (coat)	Coding, Deletion N	Oryctolagus (genus) D	Domesticated	Candidate Gene	Fontanesi L; Scotti E; Allain D ; et al. (2014) A frameshift mutation in the melanophilin gene causes the dilute coat colour in rabbit (Oryctolagus [...]	GP00000648	Mlph Q91V27	Morphology	1bp deletion resulting in frameshift N	Oryctolagus (genus)	Oryctolagus (genus) D	Melanophilin (MLPH)	Oryctolagus (genus)	Published - Accepted by Curator
Microphtalmia-associated transcription factor	Coloration (feathers)	Coding, Deletion N	Coturnix japonica Japanese quail - (species) D	Domesticated	Candidate Gene	Minvielle F; Bed'hom B; Coville JL ; et al. (2010) The "silver" Japanese quail and the MITF gene: causal mutation, associated traits and homology with [...]	GP00000660	Mitf Q08874	Morphology	2bp deletion N	Coturnix japonica Japanese quail - (species)	Coturnix japonica Japanese quail - (species) D	Microphtalmia-associated transcription factor	Coturnix japonica Japanese quail - (species)	Published - Accepted by Curator
MLO1	Pathogen resistance	Coding, SNP N	Pisum sativum pea - (species)	Domesticated	Linkage Mapping	Pavan S; Schiavulli A; Appiano M ; et al. (2011) Pea powdery mildew er1 resistance is associated to loss-of-function mutations at a MLO homologous lo[...]	GP00000673	MLO P93766	Physiology	1bp substitution resulting in premature stop codon N	Pisum sativum pea - (species)	Pisum sativum pea - (species)	MLO1	Pisum sativum pea - (species)	Published - Accepted by Curator
MLO1	Pathogen resistance	Coding, Deletion N	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Bai Y; Pavan S; Zheng Z ; et al. (2008) Naturally occurring broad-spectrum powdery mildew resistance in a Central American tomato accession [...]	GP00000674	MLO P93766	Physiology	19bp deletion resulting in frameshift N	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species) D	MLO1	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
MTH1	Low-glucose adaptation (experimental evolution)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00000679	CUP1-1 P0CX80	Physiology	1bp substitution resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MTH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
MTH1	Low-glucose adaptation (experimental evolution)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gresham D; Desai MM; Tucker CM ; et al. (2008) The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments [...]	GP00000680	CUP1-1 P0CX80	Physiology	Ty retrotranposition resulting in a coding frameshift N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	MTH1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
mucilage-modified 2 (mum2)	Mucilage (seeds)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Domesticated	Linkage Mapping	Macquet A; Ralet MC; Loudet O ; et al. (2007) A naturally occurring mutation in an Arabidopsis accession affects a beta-D-galactosidase that incre[...]	GP00000681	BGAL6 Q9FFN4	Physiology	44bp deletion in exon 15; from Leu-662 onwards. This deletion causes a frame-shift mutation changing the next 23 amino acids followed by the introduction of a stop codon. N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	mucilage-modified 2 (mum2)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
mucilage-modified 2 (mum2)	Mucilage (seeds)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Saez-Aguayo S; Rondeau-Mouro C; Macquet A ; et al. (2014) Local evolution of seed flotation in Arabidopsis.	GP00001274	BGAL6 Q9FFN4	Physiology	C->T @position 2223 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	mucilage-modified 2 (mum2)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
mucilage-modified 2 (mum2)	Mucilage (seeds)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Saez-Aguayo S; Rondeau-Mouro C; Macquet A ; et al. (2014) Local evolution of seed flotation in Arabidopsis.	GP00001275	BGAL6 Q9FFN4	Physiology	G->C @position 2240 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	mucilage-modified 2 (mum2)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
mucilage-modified 2 (mum2)	Mucilage (seeds)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Saez-Aguayo S; Rondeau-Mouro C; Macquet A ; et al. (2014) Local evolution of seed flotation in Arabidopsis.	GP00001276	BGAL6 Q9FFN4	Physiology	G->T @position 3425 causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	mucilage-modified 2 (mum2)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
mucilage-modified 2 (mum2)	Mucilage (seeds)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Candidate Gene	Saez-Aguayo S; Rondeau-Mouro C; Macquet A ; et al. (2014) Local evolution of seed flotation in Arabidopsis.	GP00001277	BGAL6 Q9FFN4	Physiology	TACA insertion @position 4906 causing frame shift + Stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	mucilage-modified 2 (mum2)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
MYB-FL	Coloration (flower ; UV absorbance)	Coding, Deletion N	Petunia exserta (species) D	Interspecific	Linkage Mapping	Sheehan H; Moser M; Klahre U ; et al. (2016) MYB-FL controls gain and loss of floral UV absorbance, a key trait affecting pollinator preference a[...]	GP00001590	MYB-FL A0A0S3CVC7	Morphology	A 1-bp deletion in exon 3 causing a frameshift resulting in a truncated protein N	Petunia axillaris (species)	Petunia exserta (species) D	MYB-FL	Petunia exserta (species)	Published - Accepted by Curator
MYB1	Coloration (flower)	Coding, Deletion N	Ipomoea purpurea common morning-glory - (species) D	Intraspecific	Candidate Gene	Chang SM; Lu Y; Rausher MD (2005) Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea.	GP00001458	myb1 Q4QS21	Morphology	2 deletions; 6-bp and 19-bp long; the larger produces a frameshift and a premature stop N	Ipomoea purpurea common morning-glory - (species)	Ipomoea purpurea common morning-glory - (species) D	MYB1	Ipomoea purpurea common morning-glory - (species)	Published - Accepted by Curator
MYB1	Coloration (flowers; seeds; stems)	Coding, Deletion N	Ipomoea nil Japanese morning glory - (species) D	Domesticated	Candidate Gene	Morita Y; Saitoh M; Hoshino A ; et al. (2006) Isolation of cDNAs for R2R3-MYB, bHLH and WDR transcriptional regulators and identification of c and[...]	GP00002089	myb1 Q4QS21	Morphology	frameshift mutation caused by a 2 bp deletion N	Ipomoea nil Japanese morning glory - (species)	Ipomoea nil Japanese morning glory - (species) D	MYB1	Ipomoea nil Japanese morning glory - (species)	Published - Accepted by Curator
myosin heavy chain 16 (MYH16)	Masticatory muscles	Coding, Deletion N	Homo sapiens human - (species) D	Intergeneric or Higher	Candidate Gene	Stedman HH; Kozyak BW; Nelson A ; et al. (2004) Myosin gene mutation correlates with anatomical changes in the human lineage.	GP00000683	MYH16 Q9H6N6	Morphology	2bp deletion at codon 660 N	Pan troglodytes chimpanzee - (species)	Homo sapiens human - (species) D	myosin heavy chain 16 (MYH16)	Homo sapiens human - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, Deletion N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Grobet L; Martin LJ; Poncelet D ; et al. (1997) A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. 2 Additional References McPherron AC; Lee SJ (1997) Double muscling in cattle due to mutations in the myostatin gene. Kambadur R; Sharma M; Smith TP (1997) Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle.	GP00000685	MSTN O14793	Morphology	nt821 11bp deletion N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Myostatin (MSTN = GDF8)	Bos taurus cattle - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, Indel N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Grobet L; Poncelet D; Royo LJ ; et al. (1998) Molecular definition of an allelic series of mutations disrupting the myostatin function and causing[...]	GP00000686	MSTN O14793	Morphology	nt419 7bp deletion and 10bp insertion; leading to a premature stop codon at position 140 N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Myostatin (MSTN = GDF8)	Bos taurus cattle - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Grobet L; Poncelet D; Royo LJ ; et al. (1998) Molecular definition of an allelic series of mutations disrupting the myostatin function and causing[...]	GP00000687	MSTN O14793	Morphology	Q204* caused by C610T N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Myostatin (MSTN = GDF8)	Bos taurus cattle - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Grobet L; Poncelet D; Royo LJ ; et al. (1998) Molecular definition of an allelic series of mutations disrupting the myostatin function and causing[...]	GP00000688	MSTN O14793	Morphology	E226* caused by G676T N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Myostatin (MSTN = GDF8)	Bos taurus cattle - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Marchitelli C; Savarese MC; Crisà A ; et al. (2003) Double muscling in Marchigiana beef breed is caused by a stop codon in the third exon of myostatin g[...]	GP00000690	MSTN O14793	Morphology	E291* caused by G>T N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Myostatin (MSTN = GDF8)	Bos taurus cattle - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, Deletion N	Ovis aries sheep - (species) D	Domesticated	Candidate Gene	Boman IA; Klemetsdal G; Blichfeldt T ; et al. (2009) A frameshift mutation in the coding region of the myostatin gene (MSTN) affects carcass conformation[...]	GP00000693	MSTN O14793	Morphology	1bp deletion resulting in a premature stop codon at position 320 N	Ovis aries sheep - (species)	Ovis aries sheep - (species) D	Myostatin (MSTN = GDF8)	Ovis aries sheep - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Muscular mass (double muscling)	Coding, Insertion N	Ovis aries sheep - (species) D	Domesticated	Candidate Gene	Boman IA; Våge DI (2009) An insertion in the coding region of the myostatin (MSTN) gene affects carcass conformation and fatn[...]	GP00000694	MSTN O14793	Morphology	1bp insertion resulting in premature stop codon at position 49 N	Ovis aries sheep - (species)	Ovis aries sheep - (species) D	Myostatin (MSTN = GDF8)	Ovis aries sheep - (species)	Published - Accepted by Curator
Myostatin (MSTN = GDF8)	Racing performance	Coding, Deletion N	Canis lupus familiaris dog - (subspecies) D	Domesticated	Candidate Gene	Mosher DS; Quignon P; Bustamante CD ; et al. (2007) A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygo[...]	GP00000697	MSTN O14793	Morphology; Physiology	2bp deletion in the third exon N	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	Myostatin (MSTN = GDF8)	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
NAM-B1 (=Gpc-B1)	Grain content Senescence (grain)	Coding, Insertion N	Triticum turgidum (species) D	Domesticated	Linkage Mapping	Uauy C; Distelfeld A; Fahima T ; et al. (2006) A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.	GP00000717	NAM-B1 A0SPJ4	Physiology Physiology	1bp insertion resulting in frameshift N	Triticum turgidum (species)	Triticum turgidum (species) D	NAM-B1 (=Gpc-B1)	Triticum turgidum (species)	Published - Accepted by Curator
neurogenin 3	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001915	NEUROG3 Q9Y4Z2	Physiology	Absence of the gene in the genome sequence - Neurogenin-3 is a transcription factor whose activity is required for the specification of gastric epithelial cell identity - Deficiency of this factor results in considerably smaller stomachs and absence of gastrin-secreting G cells: somatostatin-secreting D cells and glucagon-secreting A cells N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	neurogenin 3	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
Oca2	Coloration (albinism) Catecholamine metabolism	Coding, Deletion N	Astyanax mexicanus Mexican tetra - (species) D	Intraspecific	Linkage Mapping	Protas ME; Hersey C; Kochanek D ; et al. (2006) Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. 2 Additional References Bilandžija H; Abraham L; Ma L (2018) Behavioural changes controlled by catecholaminergic systems explain recurrent loss of pigmentation i[...] Klaassen H; Wang Y; Adamski K (2018) CRISPR mutagenesis confirms the role of oca2 in melanin pigmentation in Astyanax mexicanus.	GP00000745	Oca2 Q62052	Morphology Physiology	Deletion of exon 21 N	Astyanax mexicanus Mexican tetra - (species)	Astyanax mexicanus Mexican tetra - (species) D	Oca2	Astyanax mexicanus Mexican tetra - (species)	Published - Accepted by Curator
Oca2	Coloration (albinism) Catecholamine metabolism	Coding, Deletion N	Astyanax mexicanus Mexican tetra - (species) D	Intraspecific	Linkage Mapping	Protas ME; Hersey C; Kochanek D ; et al. (2006) Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. 2 Additional References Bilandžija H; Abraham L; Ma L (2018) Behavioural changes controlled by catecholaminergic systems explain recurrent loss of pigmentation i[...] Klaassen H; Wang Y; Adamski K (2018) CRISPR mutagenesis confirms the role of oca2 in melanin pigmentation in Astyanax mexicanus.	GP00000746	Oca2 Q62052	Morphology Physiology	Almost complete deletion of exon 24; + 2 a.a subsitutions at conserved positions - the two point mutations do not drastically affect the function of OCA2 in cell lines suggesting that the exon 24 deletion is the mutation that causes albinism in the Pachón population N	Astyanax mexicanus Mexican tetra - (species)	Astyanax mexicanus Mexican tetra - (species) D	Oca2	Astyanax mexicanus Mexican tetra - (species)	Published - Accepted by Curator
OCA2	Coloration (albinism)	Coding, Insertion N	Pantherophis guttatus (species) D	Intraspecific	Linkage Mapping	Saenko SV; Lamichhaney S; Martinez Barrio A ; et al. (2015) Amelanism in the corn snake is associated with the insertion of an LTR-retrotransposon in the OCA2 g[...]	GP00001619	OCA2 Q04671	Morphology	insertion of an LTR-retrotransposon (5832-bp) in the 11th intron resulting after splicing in an additional 397-bp fragment constituted of 3 new exons inserted between exons 11 and 12. Generates truncated protein with two stop codons N	Pantherophis guttatus (species)	Pantherophis guttatus (species) D	OCA2	Pantherophis guttatus (species)	Published - Accepted by Curator
Oca2	Coloration (albinism)	Coding, Deletion N	Melanochromis auratus (species) D	Intraspecific	Candidate Gene	Kratochwil CF; Urban S; Meyer A (2019) Genome of the Malawi golden cichlid fish (Melanochromis auratus) reveals exon loss of oca2 in an ame[...]	GP00001955		Morphology	deletion covering a total of 5.4kb including exon 2 and parts of the flanking introns 1 and 2 N	Melanochromis auratus (species)	Melanochromis auratus (species) D	Oca2	Melanochromis auratus (species)	Published - Accepted by Curator
OCYMENE SYNTHASE (OS)	Fragrance (floral terpenoid volatiles; E- beta-ocimene)	Coding, SNP N	Erythranthe cardinalis (species) D	Interspecific	Linkage Mapping	Byers KJ; Vela JP; Peng F ; et al. (2014) Floral volatile alleles can contribute to pollinator-mediated reproductive isolation in monkeyflower[...] 1 Additional References Peng F; Byers KJRP; Bradshaw HD (2017) Less is more: Independent loss-of-function OCIMENE SYNTHASE alleles parallel pollination syndrome di[...]	GP00001760	TPS02 P0CJ43	Physiology	multiple candidate coding sequence differences - together they eliminate the ability of the enzyme to produce E-beta-ocimene - effect of individual mutations not tested N	Erythranthe lewisii (species)	Erythranthe cardinalis (species) D	OCYMENE SYNTHASE (OS)	Erythranthe cardinalis (species)	Published - Accepted by Curator
OCYMENE SYNTHASE (OS)	Fragrance (floral terpenoid volatiles; E- beta-ocimene)	Coding, Deletion N	Erythranthe verbenacea (species) D	Interspecific	Candidate Gene	Peng F; Byers KJRP; Bradshaw HD (2017) Less is more: Independent loss-of-function OCIMENE SYNTHASE alleles parallel pollination syndrome di[...]	GP00001762	TPS02 P0CJ43	Physiology	large deletion from the third exon to the last exon N	Erythranthe lewisii (species)	Erythranthe verbenacea (species) D	OCYMENE SYNTHASE (OS)	Erythranthe verbenacea (species)	Published - Accepted by Curator
OCYMENE SYNTHASE (OS)	Fragrance (floral terpenoid volatiles; E- beta-ocimene)	Coding, Insertion N	Erythranthe bicolor (species) D	Interspecific	Candidate Gene	Peng F; Byers KJRP; Bradshaw HD (2017) Less is more: Independent loss-of-function OCIMENE SYNTHASE alleles parallel pollination syndrome di[...]	GP00001763	TPS02 P0CJ43	Physiology	2-bp insertion in the second exon, producing a frameshift mutation and premature termination N	Erythranthe lewisii (species)	Erythranthe bicolor (species) D	OCYMENE SYNTHASE (OS)	Erythranthe bicolor (species)	Published - Accepted by Curator
opaque2 (O2)	Lysine content (endosperm)	Coding, Deletion N	Zea mays (species) D	Domesticated	Linkage Mapping	Schmidt RJ; Burr FA; Burr B (1987) Transposon tagging and molecular analysis of the maize regulatory locus opaque-2. 1 Additional References Hartings H; Lazzaroni N; Rossi V (1995) Molecular analysis of opaque-2 alleles from Zea mays L. reveals the nature of mutational events and [...]	GP00000753	O2 P12959	Physiology	1bp deletion predicted to cause premature termination of translation N	Zea mays (species)	Zea mays (species) D	opaque2 (O2)	Zea mays (species)	Published - Accepted by Curator
opsin - (SWS1)	Color vision	Coding, Deletion N	Mysticeti baleen whales - (suborder) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Emerling CA ; et al. (2013) Rod monochromacy and the coevolution of cetacean retinal opsins.	GP00000756	OPN1SW P03999	Physiology	4bp frameshift deletion in exon 1 of SWS1 that results in a premature stop codon N	Cetacea whales - (order)	Mysticeti baleen whales - (suborder) D	opsin - (SWS1)	Mysticeti baleen whales - (suborder)	Published - Accepted by Curator
opsin - (SWS1)	Color vision (loss of violet-range sensitivity)	Coding, Deletion N	Sciurus carolinensis gray squirrel - (species) D	Intergeneric or Higher	Candidate Gene	Carvalho Ldos S; Cowing JA; Wilkie SE ; et al. (2006) Shortwave visual sensitivity in tree and flying squirrels reflects changes in lifestyle.	GP00000758	OPN1SW P03999	Physiology	6bp deletion (residues 77-78) + 1bp frameshift deletion N	Sciurus carolinensis gray squirrel - (species)	Sciurus carolinensis gray squirrel - (species) D	opsin - (SWS1)	Sciurus carolinensis gray squirrel - (species)	Published - Accepted by Curator
opsin - rhodopsin (LWS)	Color vision	Coding, Deletion N	Balaenopteridae rorquals - (family) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Emerling CA ; et al. (2013) Rod monochromacy and the coevolution of cetacean retinal opsins.	GP00000771	OPN1LW P04000	Physiology	22bp deletion including transciption start N	Cetacea whales - (order)	Balaenopteridae rorquals - (family) D	opsin - rhodopsin (LWS)	Balaenopteridae rorquals - (family)	Published - Accepted by Curator
opsin - rhodopsin (LWS)	Color vision	Coding, Deletion N	Kogia breviceps pygmy sperm whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Emerling CA ; et al. (2013) Rod monochromacy and the coevolution of cetacean retinal opsins.	GP00000772	OPN1LW P04000	Physiology	44bp frameshift deletion 9 + possibly GT to CT splice site mutation N	Cetacea whales - (order)	Kogia breviceps pygmy sperm whale - (species) D	opsin - rhodopsin (LWS)	Kogia breviceps pygmy sperm whale - (species)	Published - Accepted by Curator
opsin - rhodopsin (LWS)	Color vision	Coding, Deletion N	Physeter catodon sperm whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Emerling CA ; et al. (2013) Rod monochromacy and the coevolution of cetacean retinal opsins.	GP00000773	OPN1LW P04000	Physiology	1bp + 28bp frameshift deletions N	Cetacea whales - (order)	Physeter catodon sperm whale - (species) D	opsin - rhodopsin (LWS)	Physeter catodon sperm whale - (species)	Published - Accepted by Curator
opsin - rhodopsin (LWS)	Color vision	Coding, Insertion N	Mesoplodon bidens Sowerby's beaked whale - (species) D	Intergeneric or Higher	Candidate Gene	Meredith RW; Gatesy J; Emerling CA ; et al. (2013) Rod monochromacy and the coevolution of cetacean retinal opsins.	GP00000774	OPN1LW P04000	Physiology	4bp frameshift insertion in exon 2 of LWS N	Cetacea whales - (order)	Mesoplodon bidens Sowerby's beaked whale - (species) D	opsin - rhodopsin (LWS)	Mesoplodon bidens Sowerby's beaked whale - (species)	Published - Accepted by Curator
Os07g0603400	Grain size Grain quality	2 Mutations: Coding SNP N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Wang Y; Xiong G; Hu J ; et al. (2015) Copy number variation at the GL7 locus contributes to grain size diversity in rice.	GP00001542	Os07g0603400 A3BLY4	Morphology Physiology	2 mutations	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Os07g0603400	Oryza sativa rice - (species)	Published - Accepted by Curator
OsC1	Coloration (loss of apiculus color)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Saitoh K; Onishi K; Mikami I ; et al. (2004) Allelic diversification at the C (OsC1) locus of wild and cultivated rice: nucleotide changes associ[...] 2 Additional References Huang X; Wei X; Sang T (2010) Genome-wide association studies of 14 agronomic traits in rice landraces. Huang X; Kurata N; Wei X (2012) A map of rice genome variation reveals the origin of cultivated rice.	GP00000805	C Q76B79	Morphology	10bp deletion N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	OsC1	Oryza sativa rice - (species)	Published - Accepted by Curator
OsC1	Coloration (loss of apiculus color)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Saitoh K; Onishi K; Mikami I ; et al. (2004) Allelic diversification at the C (OsC1) locus of wild and cultivated rice: nucleotide changes associ[...] 2 Additional References Huang X; Wei X; Sang T (2010) Genome-wide association studies of 14 agronomic traits in rice landraces. Huang X; Kurata N; Wei X (2012) A map of rice genome variation reveals the origin of cultivated rice.	GP00000806	C Q76B79	Morphology	2bp deletion N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	OsC1	Oryza sativa rice - (species)	Published - Accepted by Curator
OsCKX2=Gn1a	Grain yield	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Ashikari M; Sakakibara H; Lin S ; et al. (2005) Cytokinin oxidase regulates rice grain production.	GP00000807	CKX2 Q4ADV8	Morphology	11bp deletion causing premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	OsCKX2=Gn1a	Oryza sativa rice - (species)	Published - Accepted by Curator
OVATE	Fruit shape	Coding, SNP N	Solanum lycopersicum tomato - (species)	Domesticated	Linkage Mapping	Liu J; Van Eck J; Cong B ; et al. (2002) A new class of regulatory genes underlying the cause of pear-shaped tomato fruit.	GP00000815	Q8GSM4	Morphology	V164* caused by G>T; which leads to a 75-aa truncation in the C terminus of the predicted protein N	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species)	OVATE	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
P2RY5	Hair type (woolly)	Coding, Insertion N	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Shimomura Y; Wajid M; Ishii Y ; et al. (2008) Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair[...]	GP00000817	LPAR6 P43657	Morphology	at position 69 insertion of 4bp CATG - causes frameshift at codon 24 (PTC +29) N	Homo sapiens human - (species)	Homo sapiens human - (species) D	P2RY5	Homo sapiens human - (species)	Published - Accepted by Curator
P2RY5	Hair type (woolly)	Coding, Deletion N	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Shimomura Y; Wajid M; Ishii Y ; et al. (2008) Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair[...]	GP00001734	LPAR6 P43657	Morphology	2 deletions - one at position 172-175 delAACT and one at position 177 delG - cause frameshift at codon 58 (PTC +31) N	Homo sapiens human - (species)	Homo sapiens human - (species) D	P2RY5	Homo sapiens human - (species)	Published - Accepted by Curator
P2RY5	Hair type (woolly)	Coding, SNP N	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Shimomura Y; Wajid M; Ishii Y ; et al. (2008) Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair[...]	GP00001735	LPAR6 P43657	Morphology	188A>T which causes D63V N	Homo sapiens human - (species)	Homo sapiens human - (species) D	P2RY5	Homo sapiens human - (species)	Published - Accepted by Curator
P2RY5	Hair type (woolly)	Coding, SNP N	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Shimomura Y; Wajid M; Ishii Y ; et al. (2008) Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair[...]	GP00001736	LPAR6 P43657	Morphology	562A>T which causes I188F N	Homo sapiens human - (species)	Homo sapiens human - (species) D	P2RY5	Homo sapiens human - (species)	Published - Accepted by Curator
P2RY5	Hair type (woolly)	Coding, SNP N	Homo sapiens human - (species) D	Intraspecific	Association Mapping	Shimomura Y; Wajid M; Ishii Y ; et al. (2008) Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair[...]	GP00001737	LPAR6 P43657	Morphology	565G>A which causes E189K N	Homo sapiens human - (species)	Homo sapiens human - (species) D	P2RY5	Homo sapiens human - (species)	Published - Accepted by Curator
PAP1	Coloration (anthocyanin accumulation under high-light and low-temperature stress)	Gene Loss, Deletion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Ilk N; Ding J; Ihnatowicz A ; et al. (2015) Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attrib[...] 1 Additional References Teng S; Keurentjes J; Bentsink L (2005) Sucrose-specific induction of anthocyanin biosynthesis in Arabidopsis requires the MYB75/PAP1 gene.	GP00001232	MYB75 Q9FE25	Physiology	several deletions in the promoter; first intron; second exon and 3' UTR region (putative loss of function) N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	PAP1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
peel-1	Hybrid incompatibility	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Seidel HS; Ailion M; Li J ; et al. (2011) A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion i[...] 1 Additional References Seidel HS; Rockman MV; Kruglyak L (2008) Widespread genetic incompatibility in C. elegans maintained by balancing selection.	GP00001321	peel-1 G5EGC6	Physiology	1bp deletion creating a frameshift starting at amino acid position 43. Total length of wild-type protein is 174 amino acids. N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	peel-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
peel-1	Hybrid incompatibility	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Seidel HS; Ailion M; Li J ; et al. (2011) A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion i[...] 1 Additional References Seidel HS; Rockman MV; Kruglyak L (2008) Widespread genetic incompatibility in C. elegans maintained by balancing selection.	GP00001322	peel-1 G5EGC6	Physiology	G>T - glycine to stop codon at position 57. Total length of wild-type protein is 174 amino acids. N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	peel-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
peel-1/zeel-1	Hybrid incompatibility	Gene Loss, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Seidel HS; Rockman MV; Kruglyak L (2008) Widespread genetic incompatibility in C. elegans maintained by balancing selection. 1 Additional References Seidel HS; Ailion M; Li J (2011) A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion i[...]	GP00001320	peel-1 G5EGC6	Physiology	19kb deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	peel-1/zeel-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
pepsinogen A	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001911	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	pepsinogen A	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
pepsinogen A1	Digestion (absence of stomach)	Gene Loss, Deletion N	Danio rerio zebrafish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001917	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Gadus morhua Atlantic cod - (species) Gasterosteus aculeatus three-spined stickleback - (species) Oreochromis niloticus Nile tilapia - (species)	Danio rerio zebrafish - (species) D	pepsinogen A1	Danio rerio zebrafish - (species)	Published - Accepted by Curator
pepsinogen A1	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001924	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	pepsinogen A1	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
pepsinogen A1	Digestion (absence of stomach)	Gene Loss, Deletion N	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001930	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	pepsinogen A1	Takifugu rubripes torafugu - (species) Tetraodon nigroviridis spotted green pufferfish - (species)	Published - Accepted by Curator
pepsinogen A2	Digestion (absence of stomach)	Gene Loss, Deletion N	Danio rerio zebrafish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001918	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Gadus morhua Atlantic cod - (species) Gasterosteus aculeatus three-spined stickleback - (species) Oreochromis niloticus Nile tilapia - (species)	Danio rerio zebrafish - (species) D	pepsinogen A2	Danio rerio zebrafish - (species)	Published - Accepted by Curator
pepsinogen A2	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001925	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	pepsinogen A2	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
pepsinogen A2	Digestion (absence of stomach)	Gene Loss, Deletion N	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001931	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	pepsinogen A2	Takifugu rubripes torafugu - (species) Tetraodon nigroviridis spotted green pufferfish - (species)	Published - Accepted by Curator
pepsinogen A3	Digestion (absence of stomach)	Gene Loss, Deletion N	Danio rerio zebrafish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001919	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Gadus morhua Atlantic cod - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Danio rerio zebrafish - (species) D	pepsinogen A3	Danio rerio zebrafish - (species)	Published - Accepted by Curator
pepsinogen A3	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001926	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	pepsinogen A3	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
pepsinogen A3	Digestion (absence of stomach)	Gene Loss, Deletion N	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001927	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species)	Oryzias latipes Japanese medaka - (species) D Xiphophorus maculatus southern platyfish - (species) D	pepsinogen A3	Oryzias latipes Japanese medaka - (species) Xiphophorus maculatus southern platyfish - (species)	Published - Accepted by Curator
pepsinogen A3	Digestion (absence of stomach)	Gene Loss, Deletion N	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	Intergeneric or Higher	Candidate Gene	Castro LF; Gonçalves O; Mazan S ; et al. (2014) Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.	GP00001932	PGA4 P0DJD7	Physiology	Absence of the gene in the genome sequence - high synteny N	Oreochromis niloticus Nile tilapia - (species) Gasterosteus aculeatus three-spined stickleback - (species)	Takifugu rubripes torafugu - (species) D Tetraodon nigroviridis spotted green pufferfish - (species) D	pepsinogen A3	Takifugu rubripes torafugu - (species) Tetraodon nigroviridis spotted green pufferfish - (species)	Published - Accepted by Curator
pepsinogen B	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001913	PGB Q8SQ41	Physiology	Absence of the gene in the genome sequence - high synteny N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	pepsinogen B	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
pepsinogen C	Digestion (absence of stomach)	Gene Loss, Deletion N	Ornithorhynchus anatinus platypus - (species) D	Intergeneric or Higher	Candidate Gene	Ordoñez GR; Hillier LW; Warren WC ; et al. (2008) Loss of genes implicated in gastric function during platypus evolution.	GP00001912	PGC P20142	Physiology	Absence of the gene in the genome sequence - high synteny N	Monodelphis domestica gray short-tailed opossum - (species)	Ornithorhynchus anatinus platypus - (species) D	pepsinogen C	Ornithorhynchus anatinus platypus - (species)	Published - Accepted by Curator
PER36	Mucilage (seeds)	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Macquet A; Ralet MC; Loudet O ; et al. (2007) A naturally occurring mutation in an Arabidopsis accession affects a beta-D-galactosidase that incre[...] 1 Additional References Kunieda T; Shimada T; Kondo M (2013) Spatiotemporal secretion of PEROXIDASE36 is required for seed coat mucilage extrusion in Arabidopsis[...]	GP00001273	PER36 Q9SD46	Physiology	Tyrosine @position 262bp to a stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	PER36	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
PG	Fruit ripening	Coding, Deletion N	Capsicum annuum (species) D	Domesticated	Candidate Gene	Kim S; Park M; Yeom SI ; et al. (2014) Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum speci[...]	GP00001448	PG B9VRK6	Physiology	a partial deletion of about 90aa in the C-terminal region N	Solanum lycopersicum tomato - (species)	Capsicum annuum (species) D	PG	Capsicum annuum (species)	Published - Accepted by Curator
PG	Fruit ripening	Coding, SNP N	Capsicum chinense (species) D	Domesticated	Candidate Gene	Kim S; Park M; Yeom SI ; et al. (2014) Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum speci[...]	GP00001449	PG B9VRK6	Physiology	a point mutation in the 3' splice acceptor site of intron VIII generates a premature stop codon N	Solanum lycopersicum tomato - (species)	Capsicum chinense (species) D	PG	Capsicum chinense (species)	Published - Accepted by Curator
PH4/GmMYB-G20-1	Coloration (flowers)	Coding, SNP N	Glycine max soybean - (species)	Domesticated	Linkage Mapping	Takahashi R; Benitez ER; Oyoo ME ; et al. (2011 Jul-Aug) Nonsense mutation of an MYB transcription factor is associated with purple-blue flower color in soyb[...]	GP00000862	PH4 Q2TCH0	Morphology	Substitution creating premature Stop (codon 158) N	Glycine max soybean - (species)	Glycine max soybean - (species)	PH4/GmMYB-G20-1	Glycine max soybean - (species)	Published - Accepted by Curator
phosphoenolpyruvate carboxylase (PEPC)	C3-C4 photosynthesis (enzymatic properties)	2 Mutations: Coding SNP N	Flaveria trinervia (species)	Interspecific	Candidate Gene	Bläsing OE; Westhoff P; Svensson P (2000) Evolution of C4 phosphoenolpyruvate carboxylase in Flaveria, a conserved serine residue in the carbo[...] 1 Additional References Engelmann S; Bläsing OE; Gowik U (2003) Molecular evolution of C4 phosphoenolpyruvate carboxylase in the genus Flaveria--a gradual increase [...]	GP00000867	PPCA P30694	Physiology	2 mutations	Flaveria pringlei (species)	Flaveria trinervia (species)	phosphoenolpyruvate carboxylase (PEPC)	Flaveria trinervia (species)	Published - Accepted by Curator
phytochrome C (PHYC)	Light sensitivity	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Balasubramanian S; Sureshkumar S; Agrawal M ; et al. (2006) The PHYTOCHROME C photoreceptor gene mediates natural variation in flowering and growth responses of[...]	GP00000873	PHYC P14714	Physiology	K299*; the predicted Fr-2 PHYC protein therefore lacks half of the GAF domain; and the entire PHY; PAS and histidine kinase domains; all of which are typically required for phytochrome function N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	phytochrome C (PHYC)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
phytochrome D (PHYD)	Leaf morphology (increased petiole length) Cotyledon morphology (reduced cotyledon area) Coloration (anthocyanin accumulation in seedling stems) Plant size (diminished effect of end-of-day pulse of far red light on hypocotyl elongation) Plant architecture (decrease in number of rosette leaves at onset of flowering)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Aukerman MJ; Hirschfeld M; Wester L ; et al. (1997) A deletion in the PHYD gene of the Arabidopsis Wassilewskija ecotype defines a role for phytochrome [...]	GP00000874	PHYD P42497	Morphology Morphology Morphology Physiology Morphology	14bp deletion causing premature stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	phytochrome D (PHYD)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
phytoene synthase	Carotenoid content (fruit)	Coding, Insertion N	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Fray RG; Grierson D (1993) Identification and genetic analysis of normal and mutant phytoene synthase genes of tomato by sequen[...] 1 Additional References Gilbert C; Feschotte C (2018) Horizontal acquisition of transposable elements and viral sequences: patterns and consequences.	GP00001718	PSY1 P49085	Physiology	insertion of a Rider transposable element within the coding region N	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species) D	phytoene synthase	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
phytoene synthase	Carotenoid content (fruit)	Coding, Indel N	Solanum lycopersicum tomato - (species) D	Domesticated	Linkage Mapping	Fray RG; Grierson D (1993) Identification and genetic analysis of normal and mutant phytoene synthase genes of tomato by sequen[...] 1 Additional References Gilbert C; Feschotte C (2018) Horizontal acquisition of transposable elements and viral sequences: patterns and consequences.	GP00001719	PSY1 P49085	Physiology	r y cDNA was found to be mutated at its 3' end, lacking the last 237 bases of PSY1 coding sequence and containing 185 nucleotides of an unrelated sequence in its place N	Solanum lycopersicum tomato - (species)	Solanum lycopersicum tomato - (species) D	phytoene synthase	Solanum lycopersicum tomato - (species)	Published - Accepted by Curator
Pid3	Pathogen resistance	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Chen J; Shi Y; Liu W ; et al. (2011) A Pid3 allele from rice cultivar Gumei2 confers resistance to Magnaporthe oryzae.	GP00000883	Pid3 C0LMX9	Physiology	1bp deletion resulting in truncated protein N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Pid3	Oryza sativa rice - (species)	Published - Accepted by Curator
plg-1	Copulatory plug	Coding, Insertion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Palopoli MF; Rockman MV; TinMaung A ; et al. (2008) Molecular basis of the copulatory plug polymorphism in Caenorhabditis elegans.	GP00000898		Physiology	insertion of transposable element in an exon N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	plg-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
PMEI6	Mucilage (seeds)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Saez-Aguayo S; Rondeau-Mouro C; Macquet A ; et al. (2014) Local evolution of seed flotation in Arabidopsis. 1 Additional References Saez-Aguayo S; Ralet MC; Berger A (2013) PECTIN METHYLESTERASE INHIBITOR6 promotes Arabidopsis mucilage release by limiting methylesterificat[...]	GP00001272	AXX17_At2g45450 A0A178VVA1	Physiology	frameshift mutation due to a 1-bp insertion 581 bp after the ATG codon that changed amino acids 194 to 205 followed by the introduction of a stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	PMEI6	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
PMEL17	Coloration (coat)	Coding, SNP N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Gutiérrez-Gil B; Wiener P; Williams JL (2007) Genetic effects on coat colour in cattle: dilution of eumelanin and phaeomelanin pigments in an F2-B[...]	GP00002027	PMEL Q06154	Morphology	g.57669926G>A c.64G>A p.Gly22Arg N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	PMEL17	Bos taurus cattle - (species)	Published - Accepted by Curator
PMEL17	Coloration (coat)	Coding, Deletion N	Bos taurus cattle - (species) D	Domesticated	Candidate Gene	Jolly RD; Wills JL; Kenny JE ; et al. (2008) Coat-colour dilution and hypotrichosis in Hereford crossbred calves.	GP00002028	PMEL Q06154	Morphology	3bp deletion - g.57669913_57669915delTTC - c.50_52delTTC - p.Leu19del N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	PMEL17	Bos taurus cattle - (species)	Published - Accepted by Curator
poils au dos (pad)	Bristle number (thorax)	Coding, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Linkage Mapping	Gibert JM; Marcellini S; David JR ; et al. (2005) A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription [...]	GP00000915	pad Q9VEW6	Morphology	29bp deletion N	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	poils au dos (pad)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Pore-forming toxin-like (PFT)	Pathogen resistance (Fusarium)	Gene Loss, Indel N	Triticum aestivum bread wheat - (species)	Intraspecific	Linkage Mapping	Rawat N; Pumphrey MO; Liu S ; et al. (2016) Wheat Fhb1 encodes a chimeric lectin with agglutinin domains and a pore-forming toxin-like domain co[...]	GP00001563	Q4JEV5	Physiology	PFT gene is present and constitutively expressed in resistant line and absent in susceptible line N	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	Pore-forming toxin-like (PFT)	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
pot-2	Telomere length	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Association Mapping	Cook DE; Zdraljevic S; Tanny RE ; et al. (2016) The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.	GP00001317	pot-2 O45595	Physiology	Phenylalanine-to-isoleucine (F68I) N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	pot-2	Caenorhabditis elegans (species)	Published - Accepted by Curator
PpeGID1c	Plant size (dwarfism)	Coding, SNP N	Prunus persica peach - (species) D	Domesticated	Linkage Mapping	Hollender CA; Hadiarto T; Srinivasan C ; et al. (2016) A brachytic dwarfism trait (dw) in peach trees is caused by a nonsense mutation within the gibberell[...]	GP00000920	GID1C Q940G6	Morphology	Trp162* (TGG>TAG) N	Prunus persica peach - (species)	Prunus persica peach - (species) D	PpeGID1c	Prunus persica peach - (species)	Published - Accepted by Curator
ppw-1	Resistance to dsRNA	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Linkage Mapping	Tijsterman M; Okihara KL; Thijssen K ; et al. (2002) PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of[...]	GP00000921		Physiology	1bp deletion resulting in stop codon N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	ppw-1	Caenorhabditis elegans (species)	Published - Accepted by Curator
Prolactin	Hair length (short)	Coding, Deletion N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Littlejohn MD; Henty KM; Tiplady K ; et al. (2014) Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.	GP00002033	PRL P01239	Morphology	1-bp deletion in exon 10 that introduces a premature stop codon (p.Leu462*) and loss of 120 C-terminal amino acids from the long isoform of the receptor (ss1067289408; chr20:39136558GC>G) N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Prolactin	Bos taurus cattle - (species)	Published - Accepted by Curator
prophenoloxidase 3 (PPO3)	Immune response (melanotic encapsulation by lamellocytes)	Coding, SNP N	Drosophila sechellia (species) D	Interspecific	Candidate Gene	Dudzic JP; Kondo S; Ueda R ; et al. (2015) Drosophila innate immunity: regional and functional specialization of prophenoloxidases.	GP00001781	PPO3 Q9W1V6	Physiology	amino acid change at position 48 which converts the terminal glutamine residue of the propeptide region to a stop codon, and is predicted to generate a truncated version of the PPO3 protein N	Drosophila simulans (species) Drosophila mauritiana (species)	Drosophila sechellia (species) D	prophenoloxidase 3 (PPO3)	Drosophila sechellia (species)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time	Coding, Deletion N	Sorghum bicolor sorghum - (species) D	Domesticated	Linkage Mapping	Murphy RL; Klein RR; Morishige DT ; et al. (2011) Coincident light and clock regulation of pseudoresponse regulator protein 37 (PRR37) controls photop[...]	GP00000930	PRR37 Q0D3B6	Physiology	1bp deletion resulting in frameshift N	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species) D	PRR37 pseudoresponse regulator protein 37	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time	2 Mutations: Coding SNP N	Sorghum bicolor sorghum - (species)	Domesticated	Linkage Mapping	Murphy RL; Klein RR; Morishige DT ; et al. (2011) Coincident light and clock regulation of pseudoresponse regulator protein 37 (PRR37) controls photop[...]	GP00000931	PRR37 Q0D3B6	Physiology	2 mutations	Sorghum bicolor sorghum - (species)	Sorghum bicolor sorghum - (species)	PRR37 pseudoresponse regulator protein 37	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time (heading date)	Coding, SNP N	Oryza sativa Japonica Group Japanese rice - (no rank) D	Domesticated	Linkage Mapping	Koo BH; Yoo SC; Park JW ; et al. (2013) Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide ra[...]	GP00001632	PRR37 Q0D3B6	Physiology	Nonfunctional allele PRR37-2a: L710P missense mutation in the CONSTANS-Co-like and TOC1 domain of the protein N	Oryza sativa rice - (species)	Oryza sativa Japonica Group Japanese rice - (no rank) D	PRR37 pseudoresponse regulator protein 37	Oryza sativa Japonica Group Japanese rice - (no rank)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time (heading date)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Koo BH; Yoo SC; Park JW ; et al. (2013) Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide ra[...]	GP00001633	PRR37 Q0D3B6	Physiology	Nonfunctional allele PRR37-1a: a 8-bp deletion at position 1515 leading to frameshift N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	PRR37 pseudoresponse regulator protein 37	Oryza sativa rice - (species)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time (heading date)	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Koo BH; Yoo SC; Park JW ; et al. (2013) Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide ra[...]	GP00001634	PRR37 Q0D3B6	Physiology	Nonfunctional allele PRR37-1b: Y704H N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	PRR37 pseudoresponse regulator protein 37	Oryza sativa rice - (species)	Published - Accepted by Curator
PRR37 pseudoresponse regulator protein 37	Flowering time (heading date)	Coding, SNP N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Koo BH; Yoo SC; Park JW ; et al. (2013) Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide ra[...]	GP00001635	PRR37 Q0D3B6	Physiology	Nonfunctional allele PRR37-1c: a premature stop Q705* N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	PRR37 pseudoresponse regulator protein 37	Oryza sativa rice - (species)	Published - Accepted by Curator
PsbHLH = A	Coloration (flowers)	Coding, SNP N	Pisum sativum pea - (species)	Domesticated	Linkage Mapping	Hellens RP; Moreau C; Lin-Wang K ; et al. (2010) Identification of Mendel's white flower character.	GP00000935	BHLH E3SXU4	Morphology	Splice site mutation: a simple G to A transition in a splice donor site that leads to a mis-spliced mRNA with a premature stop codon N	Pisum sativum pea - (species)	Pisum sativum pea - (species)	PsbHLH = A	Pisum sativum pea - (species)	Published - Accepted by Curator
qPE9-1	Plant architecture Inflorescence architecture	Coding, Indel N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Zhou Y; Zhu J; Li Z ; et al. (2009) Deletion in a quantitative trait gene qPE9-1 associated with panicle erectness improves plant archit[...]	GP00000941	PAY1 B8Y995	Morphology Morphology	637-bp deletion and 12-bp insertion resulting in truncated protein N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	qPE9-1	Oryza sativa rice - (species)	Published - Accepted by Curator
qSW5	Grain size	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Shomura A; Izawa T; Ebana K ; et al. (2008) Deletion in a gene associated with grain size increased yields during rice domestication. 1 Additional References Huang X; Wei X; Sang T (2010) Genome-wide association studies of 14 agronomic traits in rice landraces.	GP00000944	qSW5 F8SPD1	Morphology	1212bp deletion N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	qSW5	Oryza sativa rice - (species)	Published - Accepted by Curator
R/glyma09g36983	Coloration (seeds)	Coding, SNP N	Glycine max soybean - (species)	Domesticated	Linkage Mapping	Gillman JD; Tetlow A; Lee JD ; et al. (2011) Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in [...] 1 Additional References Zabala G; Vodkin LO (2014) Methylation affects transposition and splicing of a large CACTA transposon from a MYB transcription [...]	GP00000946	100780023 K7LFP2	Morphology	C377- creating premature Stop N	Glycine max soybean - (species)	Glycine max soybean - (species)	R/glyma09g36983	Glycine max soybean - (species)	Published - Accepted by Curator
RAS1	Salt tolerance Abscisic acid sensitivity	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Ren Z; Zheng Z; Chinnusamy V ; et al. (2010) RAS1, a quantitative trait locus for salt tolerance and ABA sensitivity in Arabidopsis.	GP00000953	RAS1 O04515	Physiology Physiology	Premature stop codon; Lys>STOP N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RAS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Rc	Coloration (seed)	Coding, SNP N	Oryza glaberrima African rice - (species)	Domesticated	Candidate Gene	Gross BL; Steffen FT; Olsen KM (2010) The molecular basis of white pericarps in African domesticated rice: novel mutations at the Rc gene.	GP00000958	Rc A7J5U6	Morphology	Premature stop codon in exon 7; Lys>* N	Oryza glaberrima African rice - (species)	Oryza glaberrima African rice - (species)	Rc	Oryza glaberrima African rice - (species)	Published - Accepted by Curator
Rc	Coloration (seed)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Sweeney MT; Thomson MJ; Cho YG ; et al. (2007) Global dissemination of a single mutation conferring white pericarp in rice.	GP00000959	Rc A7J5U6	Morphology	14bp deletion N	Oryza rufipogon (species)	Oryza sativa rice - (species) D	Rc	Oryza sativa rice - (species)	Published - Accepted by Curator
Rc	Coloration (seed)	Coding, SNP N	Oryza sativa rice - (species)	Domesticated	Candidate Gene	Sweeney MT; Thomson MJ; Cho YG ; et al. (2007) Global dissemination of a single mutation conferring white pericarp in rice. 2 Additional References Huang X; Wei X; Sang T (2010) Genome-wide association studies of 14 agronomic traits in rice landraces. Sweeney MT; Thomson MJ; Pfeil BE (2006) Caught red-handed: Rc encodes a basic helix-loop-helix protein conditioning red pericarp in rice.	GP00000960	Rc A7J5U6	Morphology	substitution; C->A in exon 6; introduces a premature stop codon (Cys>*) that truncates the protein before the bHLH domain N	Oryza sativa rice - (species)	Oryza sativa rice - (species)	Rc	Oryza sativa rice - (species)	Published - Accepted by Curator
RCO-A/B (Reduced Complexity)	Leaf shape (simplification)	Gene Loss, Deletion N	Arabidopsis thaliana thale cress - (species) D	Interspecific	Candidate Gene	Vlad D; Kierzkowski D; Rast MI ; et al. (2014) Leaf shape evolution through duplication, regulatory diversification, and loss of a homeobox gene.	GP00000962	RCO A0A023NDU4	Morphology	Gene deletion N	Arabidopsis (genus)	Arabidopsis thaliana thale cress - (species) D	RCO-A/B (Reduced Complexity)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Gene Loss, Deletion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001247	At4g11040 Q9T010	Physiology	gene loss: -5.7KB at position -4.38KB N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001248	At4g11040 Q9T010	Physiology	-23bp at position 1371 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001249	At4g11040 Q9T010	Physiology	-25bp at position 25 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001250	At4g11040 Q9T010	Physiology	-50bp at position 50; -390bp at position 504 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001251	At4g11040 Q9T010	Physiology	-13bp at position 1440 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001252	At4g11040 Q9T010	Physiology	-2bp at position 1456 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001253	At4g11040 Q9T010	Physiology	-4bp at position 1391 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001254	At4g11040 Q9T010	Physiology	-16bp at position 1054 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001255	At4g11040 Q9T010	Physiology	-19bp at position 594 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001256	At4g11040 Q9T010	Physiology	-2bp at position 606 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001257	At4g11040 Q9T010	Physiology	-4bp at position 11 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001258	At4g11040 Q9T010	Physiology	C684A which causes C135* N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001259	At4g11040 Q9T010	Physiology	4 amino acid changes: N45K; G54R; T55K; E208A - the effect of each single amino acid change has not been tested N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001260	At4g11040 Q9T010	Physiology	-1bp at position 498 causing premature STOP N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RDO5 REDUCED DORMANCY5	Seed dormancy	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Xiang Y; Song B; Née G ; et al. (2016) Sequence Polymorphisms at the REDUCED DORMANCY5 Pseudophosphatase Underlie Natural Variation in Arab[...] 1 Additional References Bentsink L; Hanson J; Hanhart CJ (2010) Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pa[...]	GP00001261	At4g11040 Q9T010	Physiology	-1bp at position 498 causing premature STOP N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RDO5 REDUCED DORMANCY5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Reduced height-1 (Rht1)	Plant size (dwarfism)	Coding, SNP N	Helianthus annuus common sunflower - (species) D	Domesticated	Linkage Mapping	Ramos ML; Altieri E; Bulos M ; et al. (2013) Phenotypic characterization, genetic mapping and candidate gene analysis of a source conferring redu[...]	GP00001728	D8 Q9ST48	Morphology	T-to-C transition corresponding to nucleotide positions 143 - the SNP at position 143 converts a leucine residue in a proline within the conserved DELLA motif—This amino acid position corresponds to amino acid position 57 in the full-length amino acid sequence encoded by the L. sativa DELLA1 nucleotide sequence of GenBank Accession No. BAG71200.1 N	Helianthus annuus common sunflower - (species)	Helianthus annuus common sunflower - (species) D	Reduced height-1 (Rht1)	Helianthus annuus common sunflower - (species)	Published - Accepted by Curator
Reduced height-B1 (RhtB1)	Plant size (dwarfism)	Coding, SNP N	Triticum aestivum bread wheat - (species)	Domesticated	Linkage Mapping	Peng J; Richards DE; Hartley NM ; et al. (1999) 'Green revolution' genes encode mutant gibberellin response modulators.	GP00000965	D8 Q9ST48	Morphology	Q64*; TGA>CGA N	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	Reduced height-B1 (RhtB1)	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
Reduced height-D1 (RhtD1)	Plant size (dwarfism)	Coding, SNP N	Triticum aestivum bread wheat - (species)	Domesticated	Linkage Mapping	Peng J; Richards DE; Hartley NM ; et al. (1999) 'Green revolution' genes encode mutant gibberellin response modulators.	GP00000966	D8 Q9ST48	Morphology	E61*; GGA>TGA N	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	Reduced height-D1 (RhtD1)	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
resistant to methyl viologen 1 (RMV1)	Polyamine uptake	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Fujita M; Fujita Y; Iuchi S ; et al. (2012) Natural variation in a polyamine transporter determines paraquat tolerance in Arabidopsis.	GP00000982	RMV1 Q9FFL1	Physiology	Ile377Phe N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	resistant to methyl viologen 1 (RMV1)	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RIM15	Low-glucose adaptation (experimental evolution)	Coding, Deletion N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Kao KC; Sherlock G (2008) Molecular characterization of clonal interference during adaptive evolution in asexual populations o[...] 1 Additional References Kvitek DJ; Sherlock G (2011) Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugg[...]	GP00000989	RIM15 P43565	Physiology	1bp deletion resulting in premature stop codon N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	RIM15	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
RLM1	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Bohman S ; et al. (2006) Transgressive segregation reveals two Arabidopsis TIR-NB-LRR resistance genes effective against Lept[...]	GP00000991	RLM1A F4I594	Physiology	Digenic; deletion of gene1 and premature stop codons in gene2 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RLM2 cluster	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Bohman S ; et al. (2006) Transgressive segregation reveals two Arabidopsis TIR-NB-LRR resistance genes effective against Lept[...]	GP00000992	RLM1B Q9CAK1	Physiology	the locus contains two paralogues; one of which is deleted and the other pseudogenized in Ler-0 N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM2 cluster	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RLM3	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Staal J; Kaliff M; Dewaele E ; et al. (2008) RLM3, a TIR domain encoding gene involved in broad-range immunity of Arabidopsis to necrotrophic fun[...]	GP00000993	RLM3 Q9FT77	Physiology	gene deletion N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RLM3	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPM1	Pathogen resistance	Gene Loss, Indel N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Grant MR; McDowell JM; Sharpe AG ; et al. (1998) Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis. 2 Additional References Atwell S; Huang YS; Vilhjálmsson BJ (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Stahl EA; Dwyer G; Mauricio R (1999) Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis.	GP00001000	RPM1 Q39214	Physiology	3.7kb indel with a null-state in the sensitive strains N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPM1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPM1	Pathogen resistance	Gene Loss, Complex Change N	Brassica napus rape - (species)	Intraspecific	Linkage Mapping	Grant MR; McDowell JM; Sharpe AG ; et al. (1998) Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis.	GP00001001	RPM1 Q39214	Physiology	deletion N	Brassica napus rape - (species)	Brassica napus rape - (species)	RPM1	Brassica napus rape - (species)	Published - Accepted by Curator
RPS2	Pathogen resistance	Coding, Insertion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Mindrinos M; Katagiri F; Yu GL ; et al. (1994) The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site [...]	GP00001011	RPS2 Q42484	Physiology	10bp insertion close to the 5' end causing a frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RPS2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS2	Pathogen resistance	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Caicedo AL; Schaal BA; Kunkel BN (1999) Diversity and molecular evolution of the RPS2 resistance gene in Arabidopsis thaliana.	GP00001012	RPS2 Q42484	Physiology	W235* due to G704A N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPS2	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS4	Pathogen resistance	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Narusaka M; Shirasu K; Noutoshi Y ; et al. (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens. 1 Additional References Narusaka M; Shirasu K; Noutoshi Y (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens.	GP00001013	RPS4 Q9XGM3	Physiology	5bp deletion resulting in frameshift N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	RPS4	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RPS5	Pathogen resistance	Gene Loss, Complex Change N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Henk AD; Warren RF; Innes RW (1999) A new Ac-like transposon of Arabidopsis is associated with a deletion of the RPS5 disease resistance[...] 1 Additional References Atwell S; Huang YS; Vilhjálmsson BJ (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines.	GP00001014	RPS5 O64973	Physiology	Deletion N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RPS5	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
RRS1	Pathogen resistance	Coding, SNP N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Narusaka M; Shirasu K; Noutoshi Y ; et al. (2009) RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens. 1 Additional References Birker D; Heidrich K; Takahara H (2009) A locus conferring resistance to Colletotrichum higginsianum is shared by four geographically distin[...]	GP00001015	RRS1 P0DKH5	Physiology	Premature stop codon N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	RRS1	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
SCARB1	Carotenoid content	Coding, SNP N	Serinus canaria common canary - (species) D	Intraspecific	Linkage Mapping	Toomey MB; Lopes RJ; Araújo PM ; et al. (2017) High-density lipoprotein receptor SCARB1 is required for carotenoid coloration in birds.	GP00001681	Scarb1 Q61009	Morphology	T>G nucleotide substitution in the splice-donor site immediately downstream of exon 4 of the SCARB1 gene. This mutation results in abnormal splicing; with the most abundant transcript lacking exon 4. Isoform 4 of SCARB1; the most abundant transcript isoform in the white recessive canary; is predicted to lack 68 amino acids; a deficiency which disrupts SCARB1 protein function. N	Serinus canaria common canary - (species)	Serinus canaria common canary - (species) D	SCARB1	Serinus canaria common canary - (species)	Published - Accepted by Curator
SCR	Self-incompatibility (loss)	Coding, Inversion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Candidate Gene	Tsuchimatsu T; Suwabe K; Shimizu-Inatsugi R ; et al. (2010) Evolution of self-compatibility in Arabidopsis by a mutation in the male specificity gene. 1 Additional References Shimizu KK; Shimizu-Inatsugi R; Tsuchimatsu T (2008) Independent origins of self-compatibility in Arabidopsis thaliana.	GP00001271	SCRA P0CG07	Physiology	213 bp inversion causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	SCR	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
SCRB15	Coloration (silk; carotenoids)	Coding, Insertion N	Bombyx mori domestic silkworm - (species) D	Domesticated	Linkage Mapping	Sakudoh T; Kuwazaki S; Iizuka T ; et al. (2013) CD36 homolog divergence is responsible for the selectivity of carotenoid species migration to the si[...]	GP00001904	SCRB15 K7ZRZ1	Morphology	In the F mutant SCRB15 mRNA structure was severely disrupted due to a 1.4 kb genomic insertion in a coding exon N	Bombyx mori domestic silkworm - (species)	Bombyx mori domestic silkworm - (species) D	SCRB15	Bombyx mori domestic silkworm - (species)	Published - Accepted by Curator
Sd1 (=GA20ox-2)	Plant size (dwarfism)	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Sasaki A; Ashikari M; Ueguchi-Tanaka M ; et al. (2002) Green revolution: a mutant gibberellin-synthesis gene in rice. 3 Additional References Ashikari M; Sakakibara H; Lin S (2005) Cytokinin oxidase regulates rice grain production. Monna L; Kitazawa N; Yoshino R (2002) Positional cloning of rice semidwarfing gene, sd-1: rice "green revolution gene" encodes a mutant en[...] Spielmeyer W; Ellis MH; Chandler PM (2002) Semidwarf (sd-1), "green revolution" rice, contains a defective gibberellin 20-oxidase gene.	GP00001028	GA20OX2 Q0JH50	Morphology	383bp deletion introducing premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	Sd1 (=GA20ox-2)	Oryza sativa rice - (species)	Published - Accepted by Curator
se5	Flowering time	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Izawa T; Oikawa T; Tokutomi S ; et al. (2000) Phytochromes confer the photoperiodic control of flowering in rice (a short-day plant).	GP00001034	HO1 Q69XJ4	Physiology	1bp deletion in exon 1; causes a frameshift and a premature stop codon N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	se5	Oryza sativa rice - (species)	Published - Accepted by Curator
Serine/threonine protein kinase RIM15	Nitrogen use (growth efficiency)	Coding, Insertion N	Saccharomyces cerevisiae baker's yeast - (species) D	Intraspecific	Linkage Mapping	Ibstedt S; Stenberg S; Bagés S ; et al. (2015) Concerted evolution of life stage performances signals recent selection on yeast nitrogen use.	GP00001500	RIM15 P43565	Physiology	2 bp insertion 459_460insCA shifting the reading frame to cause an early stop codon (null allele) N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Serine/threonine protein kinase RIM15	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
SG3/At4g30720	Growth (shoots)	Coding, Deletion N	Arabidopsis thaliana thale cress - (species) D	Intraspecific	Linkage Mapping	Vlad D; Rappaport F; Simon M ; et al. (2010) Gene transposition causing natural variation for growth in Arabidopsis thaliana.	GP00001036	PDE327 F4JQE2	Physiology	Premature stop codon at the SG3 locus in Bur-0 (a 1bp deletion in exon four of At4g30720 results in a frame shift; predicting a premature stop codon which terminates the ORF after 5 amino acids); but in this accession this gene has a functional copy at a N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species) D	SG3/At4g30720	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
Shattering1 - OsSh1	Seed shattering	Gene Loss, Deletion N	Oryza glaberrima African rice - (species) D	Domesticated	Association Mapping	Wang M; Yu Y; Haberer G ; et al. (2014) The genome sequence of African rice (Oryza glaberrima) and evidence for independent domestication.	GP00001038	YAB2 Q10FZ7	Physiology	45kb deletion resulting in complete removal of OsSh1 in O. glaberrima; resulting in seed abscission phenotype N	Oryza barthii (species)	Oryza glaberrima African rice - (species) D	Shattering1 - OsSh1	Oryza glaberrima African rice - (species)	Published - Accepted by Curator
Shattering1 - Sh1	Seed shattering	Coding, Deletion N	Sorghum bicolor sorghum - (species) D	Domesticated	Linkage Mapping	Lin Z; Li X; Shannon LM ; et al. (2012) Parallel domestication of the Shattering1 genes in cereals.	GP00001040	YAB2 Q10FZ7	Physiology	2.2kb deletion at the location of exons 2 and 3 N	Sorghum virgatum (species)	Sorghum bicolor sorghum - (species) D	Shattering1 - Sh1	Sorghum bicolor sorghum - (species)	Published - Accepted by Curator
SIGLEC13	Pathogen resistance	Gene Loss, Complex Change N	Homo sapiens human - (species)	Interspecific	Candidate Gene	Wang X; Mitra N; Secundino I ; et al. (2012) Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.	GP00001052	SIGLEC13 Q64JA4	Physiology	Gene deletion by Alu-mediated recombination N	Primates (order)	Homo sapiens human - (species)	SIGLEC13	Homo sapiens human - (species)	Published - Accepted by Curator
SIGLEC17P (pseudogene)	Pathogen resistance	Coding, Deletion N	Homo sapiens human - (species) D	Interspecific	Candidate Gene	Wang X; Mitra N; Secundino I ; et al. (2012) Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.	GP00001053	SIGLEC13 Q64JA4	Physiology	1bp deletion resulting in frame-shift (pseudogenization) N	Primates (order)	Homo sapiens human - (species) D	SIGLEC17P (pseudogene)	Homo sapiens human - (species)	Published - Accepted by Curator
SLB1/2	Pathogen resistance (Root parasitic plant) (root parasitic plant)	Gene Loss, Deletion N	Oryza sativa rice - (species)	Intraspecific	Linkage Mapping	Cardoso C; Zhang Y; Jamil M ; et al. (2014) Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 ort[...]	GP00001631	Os01g0700900 M9R6D3	Physiology	deletion of 2 cytochrome P450 genes (Os010700900 & Os01g0701400) N	Oryza sativa rice - (species)	Oryza sativa rice - (species)	SLB1/2	Oryza sativa rice - (species)	Published - Accepted by Curator
SLC45A2=MATP	Coloration (eyes; fur)	Coding, Deletion N	Gallus gallus chicken - (species) D	Domesticated	Linkage Mapping	Gunnarsson U; Hellström AR; Tixier-Boichard M ; et al. (2007) Mutations in SLC45A2 cause plumage color variation in chicken and Japanese quail.	GP00001059	SLC45A2 Q9UMX9	Morphology	1bp deletion at codon 36; resulting in frameshift and a premature stop codon in exon 1; the corresponding mRNA appears to be degraded by Nonsense-mediated mRNA decay. N	Gallus gallus chicken - (species)	Gallus gallus chicken - (species) D	SLC45A2=MATP	Gallus gallus chicken - (species)	Published - Accepted by Curator
SlMYBATV	Coloration (anthocyanin accumulation in fruits)	Coding, Insertion N	Solanum cheesmaniae (species) D	Intraspecific	Linkage Mapping	Cao X; Qiu Z; Wang X ; et al. (2017) A putative R3 MYB repressor is the candidate gene underlying atroviolacium, a locus for anthocyanin [...]	GP00001906	CPC O22059	Morphology; Physiology	SlMYBATV encodes a R3 MYB transcription factor. 4-bp insertion predicted to result in a frame-shift that would alter the protein sequence from amino-acid position 20 onwards by inducing premature termination of translation including the R3/bHLH-binding domain N	Solanum lycopersicum tomato - (species)	Solanum cheesmaniae (species) D	SlMYBATV	Solanum cheesmaniae (species)	Published - Accepted by Curator
squalene synthase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Caenorhabditis elegans (species) D	Intergeneric or Higher	Candidate Gene	Kurzchalia TV; Ward S (2003) Why do worms need cholesterol? 1 Additional References Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001947	FDFT1 P37268	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Caenorhabditis elegans (species) D	squalene synthase	Caenorhabditis elegans (species)	Published - Accepted by Curator
squalene synthase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intergeneric or Higher	Candidate Gene	Kurzchalia TV; Ward S (2003) Why do worms need cholesterol? 1 Additional References Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001948	FDFT1 P37268	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Drosophila melanogaster fruit fly - (species) D	squalene synthase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
srg-34	Diapause (resistance to dauer-inducing pheromone)	Gene Loss, Deletion N	Caenorhabditis briggsae (species)	Domesticated	Linkage Mapping	McGrath PT; Xu Y; Ailion M ; et al. (2011) Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes.	GP00001074	srg-34 Q9XXQ5	Physiology	33kb deletion N	Caenorhabditis briggsae (species)	Caenorhabditis briggsae (species)	srg-34	Caenorhabditis briggsae (species)	Published - Accepted by Curator
srg-36/37	Diapause (resistance to dauer-inducing pheromone)	Gene Loss, Deletion N	Caenorhabditis elegans (species)	Domesticated	Linkage Mapping	McGrath PT; Xu Y; Ailion M ; et al. (2011) Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes.	GP00001075	srg-34 Q9XXQ5	Physiology	6795bp deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species)	srg-36/37	Caenorhabditis elegans (species)	Published - Accepted by Curator
srg-36/37	Diapause (resistance to dauer-inducing pheromone)	Gene Loss, Deletion N	Caenorhabditis elegans (species)	Domesticated	Linkage Mapping	McGrath PT; Xu Y; Ailion M ; et al. (2011) Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes.	GP00001076	srg-34 Q9XXQ5	Physiology	4906bp deletion N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species)	srg-36/37	Caenorhabditis elegans (species)	Published - Accepted by Curator
Starch branching enzyme (SBEI) = rugosus (R)	Starch structure Seed aspect	Coding, Insertion N	Pisum sativum pea - (species) D	Domesticated	Linkage Mapping	Bhattacharyya MK; Smith AM; Ellis TH ; et al. (1990) The wrinkled-seed character of pea described by Mendel is caused by a transposon-like insertion in a[...]	GP00001078	SBEI Q41058	Physiology Morphology	800 bp TE insertion; probably disrupts the last 61 amino acids of the SBEI protein N	Pisum sativum pea - (species)	Pisum sativum pea - (species) D	Starch branching enzyme (SBEI) = rugosus (R)	Pisum sativum pea - (species)	Published - Accepted by Curator
StCDF1	Latitudinal adaptation	Coding, Insertion N	Solanum tuberosum potato - (species) D	Domesticated	Linkage Mapping	Kloosterman B; Abelenda JA; Gomez Mdel M ; et al. (2013) Naturally occurring allele diversity allows potato cultivation in northern latitudes.	GP00001079	CDF1 Q8W1E3	Physiology	+7bp insertion resulting in frameshift and truncated protein N	Solanum tuberosum potato - (species)	Solanum tuberosum potato - (species) D	StCDF1	Solanum tuberosum potato - (species)	Published - Accepted by Curator
sterol C5 desaturase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intergeneric or Higher	Candidate Gene	Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001953	ERG3 P32353	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Drosophila melanogaster fruit fly - (species) D	sterol C5 desaturase	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
sterol C5 desaturase	Cholesterol metabolism (cholesterol biosynthesis)	Gene Loss, Deletion N	Caenorhabditis elegans (species) D	Intergeneric or Higher	Candidate Gene	Vinci G; Xia X; Veitia RA (2008) Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.	GP00001954	ERG3 P32353	Physiology	gene absent in the genome N	Homo sapiens human - (species)	Caenorhabditis elegans (species) D	sterol C5 desaturase	Caenorhabditis elegans (species)	Published - Accepted by Curator
str-217	Xenobiotic resistance (insecticide; DEET)	Coding, Deletion N	Caenorhabditis elegans (species) D	Intraspecific	Candidate Gene	Dennis EJ; Dobosiewicz M; Jin X ; et al. (2018) A natural variant and engineered mutation in a GPCR promote DEET resistance in C. elegans.	GP00001783	str-217 Q9XX85	Physiology	deletion that leads to a predicted frame shift and early stop codon - the predicted resulting protein has only one transmembrane domain instead of the 7 transmembrane domains - 138-bp deletion in exon 2 and 3 and intervening intron according to https://www.wormbase.org/species/c_elegans/variation/WBVar02076179#02-45-3 and email from Emily Dennis from 9 March 2019 N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	str-217	Caenorhabditis elegans (species)	Published - Accepted by Curator
str-217	Xenobiotic resistance (insecticide; DEET)	Coding, SNP N	Caenorhabditis elegans (species) D	Intraspecific	Candidate Gene	Dennis EJ; Dobosiewicz M; Jin X ; et al. (2018) A natural variant and engineered mutation in a GPCR promote DEET resistance in C. elegans.	GP00001784	str-217 Q9XX85	Physiology	on chromosome V position 17000292 G>A stop_gained 13C>T - Gln5* N	Caenorhabditis elegans (species)	Caenorhabditis elegans (species) D	str-217	Caenorhabditis elegans (species)	Published - Accepted by Curator
TaPHS1	Seed dormancy	Coding, SNP N	Triticum aestivum bread wheat - (species)	Domesticated	Linkage Mapping	Liu S; Sehgal SK; Li J ; et al. (2013) Cloning and characterization of a critical regulator for preharvest sprouting in wheat.	GP00001104	PHS1 D2J2Y0	Physiology	GT-to-AT transition at the 5_ donor splice site (position +646) of intron 3 AND Premature Stop Codon (position +666) N	Triticum aestivum bread wheat - (species)	Triticum aestivum bread wheat - (species)	TaPHS1	Triticum aestivum bread wheat - (species)	Published - Accepted by Curator
Taqpep	Coloration (coat)	Coding, Insertion N	Acinonyx jubatus cheetah - (species) D	Intraspecific	Candidate Gene	Kaelin CB; Xu X; Hong LZ ; et al. (2012) Specifying and sustaining pigmentation patterns in domestic and wild cats.	GP00001105	Lvrn Q2KHK3	Morphology	1bp insertion resulting in frameshift N	Acinonyx jubatus cheetah - (species)	Acinonyx jubatus cheetah - (species) D	Taqpep	Acinonyx jubatus cheetah - (species)	Published - Accepted by Curator
Taqpep	Coloration (coat)	Coding, SNP N	Felis catus domestic cat - (species)	Intraspecific	Candidate Gene	Kaelin CB; Xu X; Hong LZ ; et al. (2012) Specifying and sustaining pigmentation patterns in domestic and wild cats.	GP00001107	Lvrn Q2KHK3	Morphology	S59stop N	Felis catus domestic cat - (species)	Felis catus domestic cat - (species)	Taqpep	Felis catus domestic cat - (species)	Published - Accepted by Curator
Taqpep	Coloration (coat)	Coding, SNP N	Felis catus domestic cat - (species)	Intraspecific	Linkage Mapping	Kaelin CB; Xu X; Hong LZ ; et al. (2012) Specifying and sustaining pigmentation patterns in domestic and wild cats.	GP00001108	Lvrn Q2KHK3	Morphology	W841stop N	Felis catus domestic cat - (species)	Felis catus domestic cat - (species)	Taqpep	Felis catus domestic cat - (species)	Published - Accepted by Curator
TAS1R1	Taste sensitivity (umami)	Coding, Deletion N	Ailurus fulgens lesser panda - (species) D	Interspecific	Candidate Gene	Hu Y; Wu Q; Ma S ; et al. (2017) Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas.	GP00001415	Tas1r1 Q99PG6	Physiology	1bp deletion (deletion of a C) in the sixth exon; N	Ursus maritimus polar bear - (species)	Ailurus fulgens lesser panda - (species) D	TAS1R1	Ailurus fulgens lesser panda - (species)	Published - Accepted by Curator
TAS1R1	Taste sensitivity (umami)	Coding, Deletion N	Ailuropoda melanoleuca giant panda - (species) D	Interspecific	Candidate Gene	Li R; Fan W; Tian G ; et al. (2010) The sequence and de novo assembly of the giant panda genome. 2 Additional References Hu Y; Wu Q; Ma S (2017) Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas. Zhao H; Yang JR; Xu H (2010) Pseudogenization of the umami taste receptor gene Tas1r1 in the giant panda coincided with its dieta[...]	GP00001416	Tas1r1 Q99PG6	Physiology	pseudogene due to three indel mutations in the third and sixth exons. The giant panda has one 2-bp insertion on the third exon and two deletions (6-bp and 4-bp) on the sixth exon, N	Ursus maritimus polar bear - (species)	Ailuropoda melanoleuca giant panda - (species) D	TAS1R1	Ailuropoda melanoleuca giant panda - (species)	Published - Accepted by Curator
TAS1R2	Taste sensitivity (sugar)	Coding, Deletion N	Felidae cat family - (family) D	Intergeneric or Higher	Candidate Gene	Li X; Li W; Wang H ; et al. (2005) Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.	GP00001109	TAS1R2 Q8TE23	Physiology	247bp deletion in exon 3 and stop codons in exons 4 and 6. N	Mammalia mammals - (class)	Felidae cat family - (family) D	TAS1R2	Felidae cat family - (family)	Published - Accepted by Curator
THOUSAND-GRAIN WEIGHT 6 (TGW6)	Grain yield	Coding, Deletion N	Oryza sativa rice - (species) D	Domesticated	Linkage Mapping	Ishimaru K; Hirotsu N; Madoka Y ; et al. (2013) Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yie[...]	GP00001126	TGW6 Q69U01	Morphology	-1bp at +313 resulting in truncated protein N	Oryza sativa rice - (species)	Oryza sativa rice - (species) D	THOUSAND-GRAIN WEIGHT 6 (TGW6)	Oryza sativa rice - (species)	Published - Accepted by Curator
timeless (tim)	Diapause Locomotor activity	Coding, Insertion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Candidate Gene	Tauber E; Zordan M; Sandrelli F ; et al. (2007) Natural selection favors a newly derived timeless allele in Drosophila melanogaster. 1 Additional References Sandrelli F; Tauber E; Pegoraro M (2007) A molecular basis for natural selection at the timeless locus in Drosophila melanogaster.	GP00001129	TIMELESS Q9UNS1	Physiology Behavior; Physiology	1bp insertion; allows production of longer protein from upstream start codon N	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	timeless (tim)	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
TPD3	Cell size	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Spor A; Kvitek DJ; Nidelet T ; et al. (2014) Phenotypic and genotypic convergences are influenced by historical contingency and environment in ye[...]	GP00001499	TPD3 P31383	Physiology	C>T p.Q557* heterozygous nonsense mutation which may cause the larger cell size N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	TPD3	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
TT8	Coloration (seed)	Coding, Insertion N	Brassica rapa field mustard - (species) D	Domesticated	Linkage Mapping	Li X; Chen L; Hong M ; et al. (2012) A large insertion in bHLH transcription factor BrTT8 resulting in yellow seed coat in Brassica rapa.	GP00002077	TT8 Q9FT81	Morphology	insertion of a Helitron transposon of 4320 bp in intron 2 starting with 5' TC and ending with 3'CTAG containing a 17 bp palindromic region forming a hairpin - prevents transcription N	Brassica rapa field mustard - (species)	Brassica rapa field mustard - (species) D	TT8	Brassica rapa field mustard - (species)	Published - Accepted by Curator
Twist1	Horn shape (scurs)	Coding, Insertion N	Bos taurus cattle - (species) D	Domesticated	Linkage Mapping	Capitan A; Grohs C; Weiss B ; et al. (2011) A newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1.	GP00002034	Twist1 P26687	Morphology; Physiology	small duplication (c.148_157dup (p.A56RfsX87)) that causes a frameshift and inactivates the gene. N	Bos taurus cattle - (species)	Bos taurus cattle - (species) D	Twist1	Bos taurus cattle - (species)	Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)	Coloration (coat)	Coding, SNP N	Canis lupus familiaris dog - (subspecies) D	Domesticated	Candidate Gene	Schmutz SM; Berryere TG; Goldfinch AD (2002) TYRP1 and MC1R genotypes and their effects on coat color in dogs.	GP00001147	Tyrp1 P07147	Morphology	premature stop codon in exon 5 (Q331ter) N	Canis lupus gray wolf - (species)	Canis lupus familiaris dog - (subspecies) D	tyrosinase-related protein 1 (TYRP1)	Canis lupus familiaris dog - (subspecies)	Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)	Coloration (coat)	Coding, SNP N	Columba livia rock pigeon - (species) D	Domesticated	Linkage Mapping	Domyan ET; Guernsey MW; Kronenberg Z ; et al. (2014) Epistatic and combinatorial effects of pigmentary gene mutations in the domestic pigeon.	GP00001150	Tyrp1 P07147	Morphology	Arg72* N	Columba livia rock pigeon - (species)	Columba livia rock pigeon - (species) D	tyrosinase-related protein 1 (TYRP1)	Columba livia rock pigeon - (species)	Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)	Coloration (coat)	Coding, Deletion N	Columba livia rock pigeon - (species) D	Domesticated	Linkage Mapping	Domyan ET; Guernsey MW; Kronenberg Z ; et al. (2014) Epistatic and combinatorial effects of pigmentary gene mutations in the domestic pigeon.	GP00001151	Tyrp1 P07147	Morphology	7-bp deletion 411-418del resulting in null allele N	Columba livia rock pigeon - (species)	Columba livia rock pigeon - (species) D	tyrosinase-related protein 1 (TYRP1)	Columba livia rock pigeon - (species)	Published - Accepted by Curator
tyrosinase-related protein 1 (TYRP1)	Coloration (coat)	Coding, SNP N	Felis catus domestic cat - (species) D	Domesticated	Linkage Mapping	Schmidt-Küntzel A; Eizirik E; O'Brien SJ ; et al. (2005 Jul-Aug) Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of th[...] 1 Additional References Lyons LA; Foe IT; Rah HC (2005) Chocolate coated cats: TYRP1 mutations for brown color in domestic cats.	GP00001153	Tyrp1 P07147	Morphology	premature UAG stop codon at position 100 of TYRP1; AAG>TAG N	Felis catus domestic cat - (species)	Felis catus domestic cat - (species) D	tyrosinase-related protein 1 (TYRP1)	Felis catus domestic cat - (species)	Published - Accepted by Curator
TZP	Plant growth (hypocotyl growth - light and temperature dependant)	Coding, Insertion N	Arabidopsis thaliana thale cress - (species)	Intraspecific	Linkage Mapping	Loudet O; Michael TP; Burger BT ; et al. (2008) A zinc knuckle protein that negatively controls morning-specific growth in Arabidopsis thaliana.	GP00001269	TZP Q9FIX7	Morphology	8bp insertion causing premature stop N	Arabidopsis thaliana thale cress - (species)	Arabidopsis thaliana thale cress - (species)	TZP	Arabidopsis thaliana thale cress - (species)	Published - Accepted by Curator
UGT86 (Bm-UGT10286)	Coloration (cocoon)	Gene Loss, Deletion N	Bombyx mori domestic silkworm - (species) D	Domesticated	Linkage Mapping	Daimon T; Hirayama C; Kanai M ; et al. (2010) The silkworm Green b locus encodes a quercetin 5-O-glucosyltransferase that produces green cocoons w[...] 1 Additional References Xu X; Wang M; Wang Y (2013) Green cocoons in silkworm Bombyx mori resulting from the quercetin 5-O-glucosyltransferase of UGT86,[...]	GP00001160	Bm-UGT10286 D6RUU6	Physiology	38kb gene deletion N	Bombyx (genus)	Bombyx mori domestic silkworm - (species) D	UGT86 (Bm-UGT10286)	Bombyx mori domestic silkworm - (species)	Published - Accepted by Curator
Ugt86Dd	Xenobiotic resistance (nicotine ; larval stage)	Coding, Deletion N	Drosophila melanogaster fruit fly - (species) D	Intraspecific	Association Mapping	Marriage TN; King EG; Long AD ; et al. (2014) Fine-mapping nicotine resistance loci in Drosophila using a multiparent advanced generation inter-cr[...] 1 Additional References Highfill CA; Tran JH; Nguyen SKT (2017) Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanoga[...]	GP00001406	Ugt86Dd Q9VGT8	Physiology	22-bp frameshift deletion in Ugt86Dd - CRISPR-induced deletions in Ugt86Dd lead to a large reduction in resistance N	Drosophila melanogaster fruit fly - (species)	Drosophila melanogaster fruit fly - (species) D	Ugt86Dd	Drosophila melanogaster fruit fly - (species)	Published - Accepted by Curator
Uncoupling protein 1 (UCP1)	Thermoregulation (brown adipose tissue)	Coding, Deletion N	Sus (genus) D	Intergeneric or Higher	Candidate Gene	Berg F; Gustafson U; Andersson L (2006) The uncoupling protein 1 gene (UCP1) is disrupted in the pig lineage: a genetic explanation for poor[...]	GP00001162	Ucp1 P12242	Physiology	deletion of exons 3 to 5 N	Mammalia mammals - (class)	Sus (genus) D	Uncoupling protein 1 (UCP1)	Sus (genus)	Published - Accepted by Curator
Vacuolar transporter chaperone 1	Metal tolerance (copper)	Coding, Indel N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001291	VTC1 P40046	Physiology	Pro > His+frameshift @ position 13 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 1	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D	Experimental Evolution	Association Mapping	Gerstein AC; Ono J; Lo DS ; et al. (2015) Too much of a good thing: the unique and repeated paths toward copper adaptation.	GP00001292	VTC1 P40046	Physiology	C>A (Ser > Stop) @ position 104 N	Saccharomyces cerevisiae baker's yeast - (species)	Saccharomyces cerevisiae baker's yeast - (species) D	Vacuolar transporter chaperone 1	Saccharomyces cerevisiae baker's yeast - (species)	Published - Accepted by Curator
Vacuolar transporter chaperone 4	Metal tolerance (copper)	Coding, SNP N	Saccharomyces cerevisiae baker's yeast - (species) D